STRINGSTRING
LEPR LEPR THPO THPO IL20RA IL20RA G3QDY6_GORGO G3QDY6_GORGO IL6R IL6R LEP LEP CSF2 CSF2 IL3 IL3 PRL PRL STAT6 STAT6 IL23A IL23A IL2RB IL2RB IL12RB1 IL12RB1 IL4R IL4R IL6ST IL6ST IL19 IL19 IL12B IL12B IL22RA1 IL22RA1 IL13 IL13 CSF3 CSF3 IL31 IL31 IL4 IL4 G3QSH5_GORGO G3QSH5_GORGO TYK2 TYK2 IFNG IFNG G3QTI0_GORGO G3QTI0_GORGO IL12RB2 IL12RB2 G3QUF1_GORGO G3QUF1_GORGO CNTFR CNTFR IL23R IL23R IL12A IL12A IL20RB IL20RB OSM OSM IFNL2 IFNL2 IL21 IL21 CLCF1 CLCF1 IFNGR1 IFNGR1 IL22 IL22 SOCS2 SOCS2 G3R446_GORGO G3R446_GORGO MPL MPL IL26 IL26 IL5 IL5 G3R8Q7_GORGO G3R8Q7_GORGO IL13RA2 IL13RA2 IL10RB IL10RB IL20 IL20 IL9 IL9 IL10 IL10 GH2 GH2 OSMR OSMR IL13RA1 IL13RA1 G3RFF0_GORGO G3RFF0_GORGO SOCS1 SOCS1 LIFR LIFR G3RH36_GORGO G3RH36_GORGO IFNE IFNE IRF9 IRF9 JAK1 JAK1 G3RLN8_GORGO G3RLN8_GORGO IFNB1 IFNB1 G3RRI7_GORGO G3RRI7_GORGO IL6 IL6 EPOR EPOR G3RVS4_GORGO G3RVS4_GORGO STAT3 STAT3 IL10RA IL10RA IFNA2 IFNA2 CSF3R CSF3R IL2 IL2 CNTF CNTF IL2RA IL2RA PTPN2 PTPN2 SOCS6 SOCS6 G3S9S6_GORGO G3S9S6_GORGO SOCS5 SOCS5 IL11 IL11 STAT1 STAT1 GH1 GH1 LIF LIF G3SKC4_GORGO G3SKC4_GORGO IL24 IL24 IL7R IL7R ENSGGOP00000030478 ENSGGOP00000030478 IL5RA IL5RA IL15RA IL15RA ENSGGOP00000032551 ENSGGOP00000032551 SOCS3 SOCS3 IFNAR1 IFNAR1 ENSGGOP00000035522 ENSGGOP00000035522 SOCS4 SOCS4 PRLR PRLR TSLP TSLP IL15 IL15 IRS4 IRS4 STAT4 STAT4 CSF2RB CSF2RB IFNA13 IFNA13 IL21R IL21R IFNLR1 IFNLR1 CISH CISH EPO EPO IL11RA IL11RA ENSGGOP00000049995 ENSGGOP00000049995 IFNAR2 IFNAR2 GHR GHR ENSGGOP00000051931 ENSGGOP00000051931
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LEPRLeptin receptor. (1154 aa)
THPOThrombopoietin. (353 aa)
IL20RAInterleukin 20 receptor subunit alpha. (553 aa)
G3QDY6_GORGOInterleukin 7. (179 aa)
IL6RInterleukin 6 receptor. (468 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (167 aa)
CSF2Colony stimulating factor 2. (144 aa)
IL3Interleukin-3; Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. Belongs to the IL-3 family. (152 aa)
PRLProlactin. (227 aa)
STAT6Signal transducer and activator of transcription. (847 aa)
IL23AInterleukin 23 subunit alpha. (189 aa)
IL2RBInterleukin 2 receptor subunit beta. (551 aa)
IL12RB1Interleukin 12 receptor subunit beta 1. (662 aa)
IL4RInterleukin 4 receptor. (825 aa)
IL6STFibronectin type-III domain-containing protein. (329 aa)
IL19Interleukin 19. (215 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (328 aa)
IL22RA1Interleukin 22 receptor subunit alpha 1. (574 aa)
IL13Interleukin 13. (170 aa)
CSF3Colony stimulating factor 3. (207 aa)
IL31Interleukin 31. (164 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (153 aa)
G3QSH5_GORGOTyrosine-protein kinase. (1124 aa)
TYK2Tyrosine-protein kinase. (1188 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
G3QTI0_GORGOSignal transducer and activator of transcription. (853 aa)
IL12RB2Interleukin 12 receptor subunit beta 2. (862 aa)
G3QUF1_GORGOColony stimulating factor 2 receptor alpha subunit. (433 aa)
CNTFRCiliary neurotrophic factor receptor. (372 aa)
IL23RInterleukin 23 receptor. (629 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa)
IL20RBInterleukin 20 receptor subunit beta. (311 aa)
OSMOncostatin M. (252 aa)
IFNL2Interferon lambda 2. (200 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
CLCF1Uncharacterized protein. (322 aa)
IFNGR1Interferon gamma receptor 1. (489 aa)
IL22Interleukin 22. (179 aa)
SOCS2Suppressor of cytokine signaling 2. (198 aa)
G3R446_GORGOInterleukin 22 receptor subunit alpha 2. (263 aa)
MPLMPL proto-oncogene, thrombopoietin receptor. (646 aa)
IL26Interleukin 26. (171 aa)
IL5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (134 aa)
G3R8Q7_GORGOInterferon omega 1. (195 aa)
IL13RA2Interleukin 13 receptor subunit alpha 2. (380 aa)
IL10RBInterleukin 10 receptor subunit beta. (325 aa)
IL20Interleukin 20. (176 aa)
IL9Interleukin 9. (144 aa)
IL10Interleukin 10. (178 aa)
GH2Uncharacterized protein. (244 aa)
OSMROncostatin M receptor. (981 aa)
IL13RA1Interleukin 13 receptor subunit alpha 1. (427 aa)
G3RFF0_GORGOFibronectin type-III domain-containing protein. (369 aa)
SOCS1Suppressor of cytokine signaling 1. (211 aa)
LIFRLIF receptor subunit alpha. (1097 aa)
G3RH36_GORGOInterferon lambda 1. (200 aa)
IFNEInterferon epsilon. (208 aa)
IRF9Interferon regulatory factor 9. (392 aa)
JAK1Tyrosine-protein kinase. (1154 aa)
G3RLN8_GORGOSignal transducer and activator of transcription. (652 aa)
IFNB1Interferon beta 1. (187 aa)
G3RRI7_GORGOUncharacterized protein. (102 aa)
IL6Interleukin 6. (234 aa)
EPORErythropoietin receptor; Receptor for erythropoietin. (508 aa)
G3RVS4_GORGOSignal transducer and activator of transcription. (787 aa)
STAT3Signal transducer and activator of transcription. (781 aa)
IL10RAInterleukin 10 receptor subunit alpha. (578 aa)
IFNA2Interferon alpha 2. (170 aa)
CSF3RColony stimulating factor 3 receptor. (836 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (153 aa)
CNTFCiliary neurotrophic factor. (200 aa)
IL2RAInterleukin 2 receptor subunit alpha. (272 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (387 aa)
SOCS6Suppressor of cytokine signaling 6. (535 aa)
G3S9S6_GORGOUncharacterized protein. (333 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
IL11Interleukin 11. (199 aa)
STAT1Signal transducer and activator of transcription. (777 aa)
GH1Uncharacterized protein. (263 aa)
LIFLIF interleukin 6 family cytokine. (202 aa)
G3SKC4_GORGOUncharacterized protein. (256 aa)
IL24Interleukin 24. (202 aa)
IL7RInterleukin 7 receptor. (458 aa)
ENSGGOP00000030478Tyrosine-protein kinase. (1151 aa)
IL5RAInterleukin 5 receptor subunit alpha. (423 aa)
IL15RASushi domain-containing protein. (323 aa)
ENSGGOP00000032551Uncharacterized protein. (210 aa)
SOCS3Suppressor of cytokine signaling 3. (225 aa)
IFNAR1Interferon alpha and beta receptor subunit 1. (558 aa)
ENSGGOP00000035522Interferon alpha 1. (198 aa)
SOCS4Suppressor of cytokine signaling 4. (440 aa)
PRLRProlactin receptor; This is a receptor for the anterior pituitary hormone prolactin. (622 aa)
TSLPThymic stromal lymphopoietin. (159 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
IRS4Insulin receptor substrate 4. (1254 aa)
STAT4Signal transducer and activator of transcription. (748 aa)
CSF2RBColony stimulating factor 2 receptor beta common subunit. (904 aa)
IFNA13Interferon alpha 13. (195 aa)
IL21RInterleukin 21 receptor. (496 aa)
IFNLR1Interferon lambda receptor 1. (520 aa)
CISHCytokine inducible SH2 containing protein. (275 aa)
EPOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (193 aa)
IL11RAGalactose-1-phosphate uridylyltransferase; Belongs to the galactose-1-phosphate uridylyltransferase type 1 family. (783 aa)
ENSGGOP00000049995Interleukin 3 receptor subunit alpha. (339 aa)
IFNAR2Uncharacterized protein. (519 aa)
GHRGrowth hormone receptor. (656 aa)
ENSGGOP00000051931Interferon gamma receptor 2. (356 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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