STRINGSTRING
BIK BIK CARD8 CARD8 BCL2 BCL2 CASP9 CASP9 CARD16 CARD16 NLRC4 NLRC4 CARD18 CARD18 BCL2L10 BCL2L10 CASP2 CASP2 GSDMC GSDMC RIPK3 RIPK3 NLRP3 NLRP3 DIABLO DIABLO AIM2 AIM2 HRK HRK G3QV30_GORGO G3QV30_GORGO BIRC8 BIRC8 NLRP2 NLRP2 G3QYB0_GORGO G3QYB0_GORGO BIRC7 BIRC7 NLRP12 NLRP12 BAX BAX NLRP7 NLRP7 BID BID CFLAR CFLAR TNFRSF10B TNFRSF10B NLRP1 NLRP1 G3R8R1_GORGO G3R8R1_GORGO CASP10 CASP10 RIPK1 RIPK1 DFFA DFFA DFFB DFFB GLMP GLMP G3RI71_GORGO G3RI71_GORGO CASP5 CASP5 MEFV MEFV MCL1 MCL1 PYCARD PYCARD DPP9 DPP9 G3RQE7_GORGO G3RQE7_GORGO BAK1 BAK1 FADD FADD BCL2L1 BCL2L1 CRADD CRADD FASLG FASLG G3SE49_GORGO G3SE49_GORGO FAS FAS CYCS CYCS CASP6 CASP6 ENSGGOP00000029367 ENSGGOP00000029367 PIDD1 PIDD1 PEA15 PEA15 ENSGGOP00000031130 ENSGGOP00000031130 ENSGGOP00000032091 ENSGGOP00000032091 ENSGGOP00000033404 ENSGGOP00000033404 GSDMB GSDMB MLKL MLKL BCL2A1 BCL2A1 APAF1 APAF1 BAD BAD BMF BMF CASP7 CASP7 ENSGGOP00000045267 ENSGGOP00000045267 NLRP6 NLRP6 BOK BOK ENSGGOP00000046758 ENSGGOP00000046758 TNFRSF10A TNFRSF10A G3RF33_GORGO G3RF33_GORGO RTL10 RTL10 BCL2L11 BCL2L11 BIRC6 BIRC6 ENSGGOP00000049412 ENSGGOP00000049412 BBC3 BBC3 TNFRSF10C TNFRSF10C
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BIKBCL2 interacting killer. (160 aa)
CARD8Caspase recruitment domain family member 8. (522 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (446 aa)
CARD16Caspase recruitment domain family member 16. (197 aa)
NLRC4NLR family CARD domain containing 4. (1024 aa)
CARD18Caspase recruitment domain family member 18. (90 aa)
BCL2L10Uncharacterized protein. (204 aa)
CASP2Caspase 2; Belongs to the peptidase C14A family. (452 aa)
GSDMCGasdermin C. (507 aa)
RIPK3Receptor interacting serine/threonine kinase 3. (518 aa)
NLRP3NLR family pyrin domain containing 3. (1028 aa)
DIABLOUncharacterized protein. (166 aa)
AIM2Absent in melanoma 2. (343 aa)
HRKActivator of apoptosis harakiri; Promotes apoptosis. (91 aa)
G3QV30_GORGOGasdermin D. (532 aa)
BIRC8Baculoviral IAP repeat-containing protein 8; Protects against apoptosis mediated by BAX. (236 aa)
NLRP2NLR family pyrin domain containing 2. (1040 aa)
G3QYB0_GORGOTNF receptor superfamily member 10d. (386 aa)
BIRC7Baculoviral IAP repeat containing 7. (298 aa)
NLRP12NLR family pyrin domain containing 12. (1065 aa)
BAXBCL2 associated X, apoptosis regulator. (217 aa)
NLRP7NLR family pyrin domain containing 7. (1037 aa)
BIDBH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (195 aa)
CFLARCASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (480 aa)
TNFRSF10BTNF receptor superfamily member 10b. (440 aa)
NLRP1NLR family pyrin domain containing 1. (1471 aa)
G3R8R1_GORGOCaspase 12 (gene/pseudogene); Belongs to the peptidase C14A family. (341 aa)
CASP10Caspase 10; Belongs to the peptidase C14A family. (523 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (671 aa)
DFFADNA fragmentation factor subunit alpha. (331 aa)
DFFBDNA fragmentation factor subunit beta. (338 aa)
GLMPGlycosylated lysosomal membrane protein. (406 aa)
G3RI71_GORGONACHT domain-containing protein. (1127 aa)
CASP5Caspase 5; Belongs to the peptidase C14A family. (447 aa)
MEFVMEFV innate immuity regulator, pyrin. (781 aa)
MCL1MCL1 apoptosis regulator, BCL2 family member. (350 aa)
PYCARDPYD and CARD domain containing. (195 aa)
DPP9Dipeptidyl peptidase 9; Belongs to the peptidase S9B family. (892 aa)
G3RQE7_GORGOCytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
BCL2L1BCL2 like 1. (233 aa)
CRADDCASP2 and RIPK1 domain containing adaptor with death domain. (199 aa)
FASLGFas ligand; Belongs to the tumor necrosis factor family. (280 aa)
G3SE49_GORGONLR family pyrin domain containing 9. (934 aa)
FASFas cell surface death receptor. (340 aa)
CYCSCytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity). (105 aa)
CASP6Caspase 6; Belongs to the peptidase C14A family. (293 aa)
ENSGGOP00000029367Pyrin domain-containing protein. (110 aa)
PIDD1P53-induced death domain protein 1. (910 aa)
PEA15Proliferation and apoptosis adaptor protein 15. (151 aa)
ENSGGOP00000031130Uncharacterized protein. (189 aa)
ENSGGOP00000032091Caspase 4; Belongs to the peptidase C14A family. (377 aa)
ENSGGOP00000033404Caspase 8; Belongs to the peptidase C14A family. (496 aa)
GSDMBGasdermin B. (416 aa)
MLKLUncharacterized protein. (178 aa)
BCL2A1BCL2 related protein A1. (196 aa)
APAF1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa)
BADBCL2 associated agonist of cell death. (168 aa)
BMFBcl2 modifying factor. (184 aa)
CASP7Caspase 7; Belongs to the peptidase C14A family. (388 aa)
ENSGGOP00000045267Uncharacterized protein; Belongs to the peptidase C14A family. (342 aa)
NLRP6Uncharacterized protein. (912 aa)
BOKBCL2 family apoptosis regulator BOK. (212 aa)
ENSGGOP00000046758Caspase 1; Belongs to the peptidase C14A family. (404 aa)
TNFRSF10ATNF receptor superfamily member 10a. (468 aa)
G3RF33_GORGOTumor necrosis factor ligand superfamily member. (281 aa)
RTL10Retrotransposon Gag like 10. (361 aa)
BCL2L11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (198 aa)
BIRC6Baculoviral IAP repeat containing 6. (4883 aa)
ENSGGOP00000049412Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (117 aa)
BBC3Uncharacterized protein. (101 aa)
TNFRSF10CTNF receptor superfamily member 10c. (284 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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