(53 nodes) Mixed, incl. VxPx cargo-targeting to cilium, and FIP domain network (Gorilla gorilla)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RAB11FIP4	RAB11 family interacting protein 4. (626 aa)
	ASAP3	ArfGAP with SH3 domain, ankyrin repeat and PH domain 3. (903 aa)
	SH3BP5	SH3 domain binding protein 5. (407 aa)
	LNPEP	Leucyl and cystinyl aminopeptidase. (1027 aa)
	CTTN	Cortactin. (634 aa)
	G3QLM0_GORGO	RAB interacting factor. (123 aa)
	G3QM81_GORGO	Uncharacterized protein. (99 aa)
	EXOC4	Exocyst complex component 4. (974 aa)
	EXOC2	Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (908 aa)
	RAB25	RAB25, member RAS oncogene family. (213 aa)
	RAB11FIP1	RAB11 family interacting protein 1. (1159 aa)
	TBC1D1	Uncharacterized protein. (1168 aa)
	RAB11FIP2	RAB11 family interacting protein 2. (532 aa)
	SLC2A4	Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
	MYO5B	Myosin VB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1848 aa)
	ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1. (1129 aa)
	RAB8B	RAB8B, member RAS oncogene family. (207 aa)
	FAM189B	Family with sequence similarity 189 member B. (668 aa)
	G3R580_GORGO	Uncharacterized protein. (701 aa)
	EXOC3	Exocyst complex component 3. (754 aa)
	RAB11A	RAB11A, member RAS oncogene family. (216 aa)
	RAB8A	RAB8A, member RAS oncogene family. (207 aa)
	MICALL2	MICAL like 2. (897 aa)
	TBC1D4	TBC1 domain family member 4. (1298 aa)
	EXOC3L4	Exocyst complex component 3 like 4. (722 aa)
	RAB11FIP5	Uncharacterized protein. (1320 aa)
	EXOC1	Exocyst complex component 1. (894 aa)
	EXOC6	Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (804 aa)
	EXOC5	Uncharacterized protein. (518 aa)
	RAB10	RAB10, member RAS oncogene family. (200 aa)
	EXOC7	Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (707 aa)
	TNFAIP2	Uncharacterized protein. (423 aa)
	RAB14	RAB14, member RAS oncogene family. (215 aa)
	EXOC8	Exocyst complex component 8. (725 aa)
	EXOC3L1	Exocyst complex component 3 like 1. (746 aa)
	RILPL2	Rab interacting lysosomal protein like 2. (211 aa)
	CEP19	Centrosomal protein 19. (167 aa)
	RAB13	Uncharacterized protein. (203 aa)
	G3SAM6_GORGO	Uncharacterized protein. (618 aa)
	RABL2B	Uncharacterized protein. (148 aa)
	RAB11B	Uncharacterized protein. (221 aa)
	EXOC1L	Exocyst complex component 1 like. (172 aa)
	ENSGGOP00000031306	Uncharacterized protein. (92 aa)
	ENSGGOP00000031837	Uncharacterized protein. (510 aa)
	GAREM1	GRB2 associated regulator of MAPK1 subtype 1. (875 aa)
	RAB3IP	RAB3A interacting protein. (479 aa)
	ENSGGOP00000034961	annotation not available (92 aa)
	ENSGGOP00000035699	GRB2 associated regulator of MAPK1 subtype 2. (779 aa)
	EXOC6B	Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (815 aa)
	ENSGGOP00000039243	annotation not available (265 aa)
	RAB11FIP3	RAB11 family interacting protein 3. (665 aa)
	ASAP2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2. (1006 aa)
	ENSGGOP00000047492	Uncharacterized protein. (451 aa)

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASAP1	ASAP2	ENSGGOP00000008533	ENSGGOP00000042263	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1.	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2.	0.901
ASAP1	ASAP3	ENSGGOP00000008533	ENSGGOP00000001141	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1.	ArfGAP with SH3 domain, ankyrin repeat and PH domain 3.	0.943
ASAP1	CTTN	ENSGGOP00000008533	ENSGGOP00000002964	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1.	Cortactin.	0.682
ASAP1	ENSGGOP00000031306	ENSGGOP00000008533	ENSGGOP00000031306	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1.	Uncharacterized protein.	0.682
ASAP1	ENSGGOP00000034961	ENSGGOP00000008533	ENSGGOP00000034961	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1.	annotation not available	0.682
ASAP1	ENSGGOP00000047492	ENSGGOP00000008533	ENSGGOP00000047492	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1.	Uncharacterized protein.	0.446
ASAP1	EXOC1	ENSGGOP00000008533	ENSGGOP00000017341	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1.	Exocyst complex component 1.	0.506
ASAP1	EXOC2	ENSGGOP00000008533	ENSGGOP00000005315	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1.	Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family.	0.521
ASAP1	EXOC4	ENSGGOP00000008533	ENSGGOP00000003879	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1.	Exocyst complex component 4.	0.492
ASAP1	EXOC5	ENSGGOP00000008533	ENSGGOP00000018952	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1.	Uncharacterized protein.	0.453
ASAP1	EXOC6	ENSGGOP00000008533	ENSGGOP00000018447	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1.	Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.	0.461
ASAP1	EXOC7	ENSGGOP00000008533	ENSGGOP00000019553	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1.	Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.	0.631
ASAP1	G3SAM6_GORGO	ENSGGOP00000008533	ENSGGOP00000025149	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1.	Uncharacterized protein.	0.453
ASAP1	RAB11A	ENSGGOP00000008533	ENSGGOP00000013901	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1.	RAB11A, member RAS oncogene family.	0.782
ASAP1	RAB11B	ENSGGOP00000008533	ENSGGOP00000028164	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1.	Uncharacterized protein.	0.465
ASAP1	RAB11FIP3	ENSGGOP00000008533	ENSGGOP00000040154	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1.	RAB11 family interacting protein 3.	0.813
ASAP1	RAB11FIP4	ENSGGOP00000008533	ENSGGOP00000001056	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1.	RAB11 family interacting protein 4.	0.501
ASAP1	RAB3IP	ENSGGOP00000008533	ENSGGOP00000034420	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1.	RAB3A interacting protein.	0.609
ASAP1	RAB8A	ENSGGOP00000008533	ENSGGOP00000014865	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1.	RAB8A, member RAS oncogene family.	0.533
ASAP1	RAB8B	ENSGGOP00000008533	ENSGGOP00000008601	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1.	RAB8B, member RAS oncogene family.	0.403