(7 nodes) cAMP response element binding, and Histone kinase activity (H3-S28 specific) network (Gorilla gorilla)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RPS6KA5	Ribosomal protein S6 kinase. (802 aa)
	CREB3L4	cAMP responsive element binding protein 3 like 4. (395 aa)
	CREB3L1	cAMP responsive element binding protein 3 like 1. (519 aa)
	ATF2	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
	ENSGGOP00000034747	Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa)
	ATF6B	Activating transcription factor 6 beta. (703 aa)
	RPS6KA4	Non-specific serine/threonine protein kinase. (511 aa)

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATF2	ATF6B	ENSGGOP00000031405	ENSGGOP00000038216	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	Activating transcription factor 6 beta.	0.916
ATF2	CREB3L1	ENSGGOP00000031405	ENSGGOP00000014811	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	cAMP responsive element binding protein 3 like 1.	0.901
ATF2	CREB3L4	ENSGGOP00000031405	ENSGGOP00000005486	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	cAMP responsive element binding protein 3 like 4.	0.904
ATF2	ENSGGOP00000034747	ENSGGOP00000031405	ENSGGOP00000034747	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription.	0.986
ATF2	RPS6KA4	ENSGGOP00000031405	ENSGGOP00000040600	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	Non-specific serine/threonine protein kinase.	0.923
ATF2	RPS6KA5	ENSGGOP00000031405	ENSGGOP00000004179	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	Ribosomal protein S6 kinase.	0.926
ATF6B	ATF2	ENSGGOP00000038216	ENSGGOP00000031405	Activating transcription factor 6 beta.	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	0.916
ATF6B	CREB3L1	ENSGGOP00000038216	ENSGGOP00000014811	Activating transcription factor 6 beta.	cAMP responsive element binding protein 3 like 1.	0.926
ATF6B	CREB3L4	ENSGGOP00000038216	ENSGGOP00000005486	Activating transcription factor 6 beta.	cAMP responsive element binding protein 3 like 4.	0.915
ATF6B	ENSGGOP00000034747	ENSGGOP00000038216	ENSGGOP00000034747	Activating transcription factor 6 beta.	Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription.	0.908
ATF6B	RPS6KA4	ENSGGOP00000038216	ENSGGOP00000040600	Activating transcription factor 6 beta.	Non-specific serine/threonine protein kinase.	0.913
ATF6B	RPS6KA5	ENSGGOP00000038216	ENSGGOP00000004179	Activating transcription factor 6 beta.	Ribosomal protein S6 kinase.	0.913
CREB3L1	ATF2	ENSGGOP00000014811	ENSGGOP00000031405	cAMP responsive element binding protein 3 like 1.	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	0.901
CREB3L1	ATF6B	ENSGGOP00000014811	ENSGGOP00000038216	cAMP responsive element binding protein 3 like 1.	Activating transcription factor 6 beta.	0.926
CREB3L1	CREB3L4	ENSGGOP00000014811	ENSGGOP00000005486	cAMP responsive element binding protein 3 like 1.	cAMP responsive element binding protein 3 like 4.	0.914
CREB3L1	ENSGGOP00000034747	ENSGGOP00000014811	ENSGGOP00000034747	cAMP responsive element binding protein 3 like 1.	Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription.	0.908
CREB3L1	RPS6KA4	ENSGGOP00000014811	ENSGGOP00000040600	cAMP responsive element binding protein 3 like 1.	Non-specific serine/threonine protein kinase.	0.900
CREB3L1	RPS6KA5	ENSGGOP00000014811	ENSGGOP00000004179	cAMP responsive element binding protein 3 like 1.	Ribosomal protein S6 kinase.	0.900
CREB3L4	ATF2	ENSGGOP00000005486	ENSGGOP00000031405	cAMP responsive element binding protein 3 like 4.	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	0.904
CREB3L4	ATF6B	ENSGGOP00000005486	ENSGGOP00000038216	cAMP responsive element binding protein 3 like 4.	Activating transcription factor 6 beta.	0.915