(31 nodes) Mixed, incl. Protein folding in endoplasmic reticulum, and ER degradation-enhancing alpha-mannosidase-like protein 1/2/3 network (Gorilla gorilla)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DNAJC3	DnaJ heat shock protein family (Hsp40) member C3. (504 aa)
	EDEM1	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (657 aa)
	EDEM3	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (932 aa)
	G3QL18_GORGO	Uncharacterized protein. (453 aa)
	ERN1	Endoplasmic reticulum to nucleus signaling 1. (977 aa)
	HYOU1	Hypoxia up-regulated 1. (999 aa)
	CANX	Calnexin. (592 aa)
	TXNDC11	Thioredoxin domain containing 11. (985 aa)
	DNAJB9	DnaJ heat shock protein family (Hsp40) member B9. (223 aa)
	EIF2AK3	Eukaryotic translation initiation factor 2 alpha kinase 3. (1116 aa)
	EDEM2	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (505 aa)
	ATF6	Activating transcription factor 6. (670 aa)
	ERO1B	Endoplasmic reticulum oxidoreductase 1 beta. (467 aa)
	G3RPU5_GORGO	Uncharacterized protein; Belongs to the heat shock protein 70 family. (613 aa)
	ERO1A	Endoplasmic reticulum oxidoreductase 1 alpha. (468 aa)
	PRDX4	Peroxiredoxin 4. (271 aa)
	PDIA4	Protein disulfide-isomerase A4. (645 aa)
	G3S6E4_GORGO	Calmegin. (596 aa)
	HSPA5	Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa)
	ANKRD45	ANK_REP_REGION domain-containing protein. (265 aa)
	HSP90B1	Heat shock protein 90 beta family member 1. (814 aa)
	P4HB	Protein disulfide-isomerase. (508 aa)
	G3SHK6_GORGO	Uncharacterized protein. (508 aa)
	CALR3	Calreticulin. (384 aa)
	ENSGGOP00000034350	Uncharacterized protein. (492 aa)
	XBP1	BZIP domain-containing protein. (380 aa)
	DNAJC10	DnaJ heat shock protein family (Hsp40) member C10. (810 aa)
	ERP29	Endoplasmic reticulum protein 29. (302 aa)
	SIL1	SIL1 nucleotide exchange factor. (468 aa)
	PDIA6	Protein disulfide isomerase family A member 6; Belongs to the protein disulfide isomerase family. (461 aa)
	TXNDC5	Uncharacterized protein; Belongs to the protein disulfide isomerase family. (361 aa)

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKRD45	ATF6	ENSGGOP00000024446	ENSGGOP00000013473	ANK_REP_REGION domain-containing protein.	Activating transcription factor 6.	0.524
ANKRD45	CALR3	ENSGGOP00000024446	ENSGGOP00000027900	ANK_REP_REGION domain-containing protein.	Calreticulin.	0.768
ANKRD45	CANX	ENSGGOP00000024446	ENSGGOP00000008258	ANK_REP_REGION domain-containing protein.	Calnexin.	0.766
ANKRD45	DNAJB9	ENSGGOP00000024446	ENSGGOP00000010487	ANK_REP_REGION domain-containing protein.	DnaJ heat shock protein family (Hsp40) member B9.	0.488
ANKRD45	DNAJC10	ENSGGOP00000024446	ENSGGOP00000042098	ANK_REP_REGION domain-containing protein.	DnaJ heat shock protein family (Hsp40) member C10.	0.926
ANKRD45	DNAJC3	ENSGGOP00000024446	ENSGGOP00000001299	ANK_REP_REGION domain-containing protein.	DnaJ heat shock protein family (Hsp40) member C3.	0.627
ANKRD45	EIF2AK3	ENSGGOP00000024446	ENSGGOP00000011491	ANK_REP_REGION domain-containing protein.	Eukaryotic translation initiation factor 2 alpha kinase 3.	0.597
ANKRD45	ENSGGOP00000034350	ENSGGOP00000024446	ENSGGOP00000034350	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.718
ANKRD45	ERN1	ENSGGOP00000024446	ENSGGOP00000006398	ANK_REP_REGION domain-containing protein.	Endoplasmic reticulum to nucleus signaling 1.	0.688
ANKRD45	ERO1A	ENSGGOP00000024446	ENSGGOP00000019259	ANK_REP_REGION domain-containing protein.	Endoplasmic reticulum oxidoreductase 1 alpha.	0.497
ANKRD45	ERO1B	ENSGGOP00000024446	ENSGGOP00000017196	ANK_REP_REGION domain-containing protein.	Endoplasmic reticulum oxidoreductase 1 beta.	0.497
ANKRD45	G3QL18_GORGO	ENSGGOP00000024446	ENSGGOP00000003159	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.787
ANKRD45	G3S6E4_GORGO	ENSGGOP00000024446	ENSGGOP00000023651	ANK_REP_REGION domain-containing protein.	Calmegin.	0.766
ANKRD45	G3SHK6_GORGO	ENSGGOP00000024446	ENSGGOP00000027595	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.787
ANKRD45	HSP90B1	ENSGGOP00000024446	ENSGGOP00000025114	ANK_REP_REGION domain-containing protein.	Heat shock protein 90 beta family member 1.	0.787
ANKRD45	HYOU1	ENSGGOP00000024446	ENSGGOP00000007855	ANK_REP_REGION domain-containing protein.	Hypoxia up-regulated 1.	0.914
ANKRD45	P4HB	ENSGGOP00000024446	ENSGGOP00000025425	ANK_REP_REGION domain-containing protein.	Protein disulfide-isomerase.	0.718
ANKRD45	PDIA4	ENSGGOP00000024446	ENSGGOP00000020717	ANK_REP_REGION domain-containing protein.	Protein disulfide-isomerase A4.	0.718
ANKRD45	PDIA6	ENSGGOP00000024446	ENSGGOP00000051032	ANK_REP_REGION domain-containing protein.	Protein disulfide isomerase family A member 6; Belongs to the protein disulfide isomerase family.	0.448
ANKRD45	SIL1	ENSGGOP00000024446	ENSGGOP00000048328	ANK_REP_REGION domain-containing protein.	SIL1 nucleotide exchange factor.	0.676