(164 nodes) U2-type spliceosomal complex, and mRNA Splicing network (Gorilla gorilla)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CWF19L2	CWF19 like cell cycle control factor 2. (894 aa)
	BUD13	BUD13 homolog. (601 aa)
	G3QEP5_GORGO	Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (61 aa)
	PHF5A	PHD finger protein 5A. (110 aa)
	SNRPF	Sm domain-containing protein. (86 aa)
	G3QFU4_GORGO	Small nuclear ribonucleoprotein polypeptide A. (282 aa)
	USP39	Ubiquitin specific peptidase 39. (565 aa)
	SF3B5	Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa)
	RNF113A	Ring finger protein 113A. (343 aa)
	SNRPD2	Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (118 aa)
	XAB2	XPA binding protein 2. (839 aa)
	CDC40	Cell division cycle 40. (579 aa)
	SF3B3	Splicing factor 3b subunit 3. (1217 aa)
	SCNM1	Sodium channel modifier 1. (195 aa)
	G3QMA7_GORGO	ISY1 splicing factor homolog. (307 aa)
	ZMAT5	Zinc finger matrin-type 5. (170 aa)
	SNRPB2	Small nuclear ribonucleoprotein polypeptide B2. (225 aa)
	PRPF38A	Pre-mRNA processing factor 38A. (312 aa)
	SNRPN	Small nuclear ribonucleoprotein-associated protein. (244 aa)
	G3QPY1_GORGO	Armadillo repeat containing 7. (198 aa)
	SF3B4	Splicing factor 3b subunit 4. (424 aa)
	TFIP11	Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...] (837 aa)
	ZMAT2	Zinc finger matrin-type 2. (199 aa)
	SNRNP200	Uncharacterized protein. (2136 aa)
	TXNL4A	Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (142 aa)
	G3QRI9_GORGO	SNRNP27 domain-containing protein. (158 aa)
	PRPF8	Pre-mRNA processing factor 8. (2335 aa)
	SLU7	SLU7 homolog, splicing factor. (586 aa)
	PDCD7	Programmed cell death 7. (485 aa)
	SF3A2	Splicing factor 3a subunit 2. (464 aa)
	CDC5L	Cell division cycle 5 like. (805 aa)
	CWC25	CWC25 spliceosome associated protein homolog. (425 aa)
	PRKRIP1	PRKR interacting protein 1. (184 aa)
	SNRNP25	Ubiquitin-like domain-containing protein. (132 aa)
	G3R0W4_GORGO	Coiled-coil domain containing 12. (179 aa)
	ZCCHC17	Zinc finger CCHC-type containing 17. (263 aa)
	SART1	Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (800 aa)
	SDE2	SDE2 telomere maintenance homolog. (451 aa)
	LSM3	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa)
	LSM7	LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. (103 aa)
	WDR25	WD_REPEATS_REGION domain-containing protein. (544 aa)
	PQBP1	Polyglutamine-binding protein 1; Intrinsically disordered protein that acts as a scaffold, and which is involved in different processes, such as pre-mRNA splicing, transcription regulation, innate immunity and neuron development. Interacts with splicing-related factors via the intrinsically disordered region and regulates alternative splicing of target pre-mRNA species. May suppress the ability of POU3F2 to transactivate the DRD1 gene in a POU3F2 dependent manner. Can activate transcription directly or via association with the transcription machinery. May be involved in ATXN1 mutant-in [...] (265 aa)
	CWC15	CWC15 spliceosome associated protein homolog. (229 aa)
	TCERG1L	Transcription elongation regulator 1 like. (491 aa)
	SNRPC	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (159 aa)
	CACTIN	Cactin, spliceosome C complex subunit. (759 aa)
	SF3A1	Splicing factor 3a subunit 1. (793 aa)
	RBM22	RNA binding motif protein 22. (420 aa)
	EFTUD2	Elongation factor Tu GTP binding domain containing 2. (972 aa)
	G3RBJ7_GORGO	Pre-mRNA processing factor 3. (580 aa)
	SNRNP48	Small nuclear ribonucleoprotein U11/U12 subunit 48. (339 aa)
	NKAP	NFKB activating protein. (416 aa)
	IK	IK cytokine. (557 aa)
	GPKOW	G-patch domain and KOW motifs. (476 aa)
	AQR	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. (1466 aa)
	CRNKL1	Crooked neck pre-mRNA splicing factor 1. (848 aa)
	SMU1	SMU1 DNA replication regulator and spliceosomal factor. (513 aa)
	CRIPT	CXXC repeat containing interactor of PDZ3 domain. (101 aa)
	DDX23	DEAD-box helicase 23. (820 aa)
	SNRPD3	Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (126 aa)
	G3RIA3_GORGO	Peptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (313 aa)
	G3RIN4_GORGO	Small nuclear ribonucleoprotein U11/U12 subunit 35. (251 aa)
	G3RJ69_GORGO	RRM domain-containing protein. (312 aa)
	G3RK55_GORGO	Pre-mRNA processing factor 31. (499 aa)
	PRPF6	Pre-mRNA processing factor 6. (941 aa)
	SNRPG	Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (96 aa)
	SNRNP40	Small nuclear ribonucleoprotein U5 subunit 40. (357 aa)
	G3RSE9_GORGO	C3H1-type domain-containing protein. (246 aa)
	G3RT30_GORGO	Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (85 aa)
	DHX16	DEAH-box helicase 16. (1050 aa)
	RBM42	RNA binding motif protein 42. (480 aa)
	G3RW70_GORGO	Sperm acrosome associated 6. (324 aa)
	BCAS2	Uncharacterized protein. (66 aa)
	G3RWU8_GORGO	Uncharacterized protein. (428 aa)
	RBMX2	RNA binding motif protein X-linked 2. (322 aa)
	SNRPA1	Small nuclear ribonucleoprotein polypeptide A. (255 aa)
	PLRG1	Pleiotropic regulator 1. (514 aa)
	GCFC2	GC-rich sequence DNA-binding factor 2. (738 aa)
	FAM32A	Family with sequence similarity 32 member A. (112 aa)
	SNW1	SNW domain containing 1. (571 aa)
	G3S6R0_GORGO	Uncharacterized protein. (297 aa)
	G3S6R2_GORGO	Uncharacterized protein. (278 aa)
	G3SA52_GORGO	RRM domain-containing protein. (290 aa)
	CWC22	CWC22 spliceosome associated protein homolog. (908 aa)
	PPIL1	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (166 aa)
	HTATSF1	HIV-1 Tat specific factor 1. (755 aa)
	YJU2	YJU2 splicing factor homolog. (323 aa)
	DAW1	Dynein assembly factor with WD repeats 1. (415 aa)
	SF3B2	Splicing factor 3b subunit 2. (895 aa)
	DHX8	DEAH-box helicase 8. (1220 aa)
	SNRNP70	Small nuclear ribonucleoprotein U1 subunit 70. (437 aa)
	WBP4	WW domain binding protein 4. (376 aa)
	G3SIL7_GORGO	Uncharacterized protein. (352 aa)
	G3SIP8_GORGO	Uncharacterized protein. (208 aa)
	ENSGGOP00000028103	annotation not available (132 aa)
	SNIP1	Smad nuclear interacting protein 1. (396 aa)
	UBL5	Ubiquitin-like domain-containing protein. (73 aa)
	SNRPD1	Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (120 aa)
	ENSGGOP00000030007	Uncharacterized protein. (57 aa)
	LSM6	LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated. (80 aa)
	RBM48	RNA binding motif protein 48. (367 aa)
	SF3B6	Splicing factor 3b subunit 6. (125 aa)
	ENSGGOP00000030598	Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (62 aa)
	ENSGGOP00000031230	Uncharacterized protein. (379 aa)
	TXNL4B	Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (149 aa)
	SRRM3	Cwf21 domain-containing protein. (558 aa)
	ENSGGOP00000031775	RRM domain-containing protein. (202 aa)
	DDX46	DEAD-box helicase 46. (1031 aa)
	SF3A3	Splicing factor 3a subunit 3. (501 aa)
	SNRPD1-2	Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (119 aa)
	ENSGGOP00000032634	SEC63 domain-containing protein. (279 aa)
	ENSGGOP00000033609	Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (64 aa)
	LSM8	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (96 aa)
	ENSGGOP00000034390	CCHC-type domain-containing protein. (200 aa)
	MFAP1	Microfibril associated protein 1. (439 aa)
	ENSGGOP00000035072	WD_REPEATS_REGION domain-containing protein. (345 aa)
	ENSGGOP00000035472	Uncharacterized protein. (59 aa)
	ENSGGOP00000035553	Sm domain-containing protein. (73 aa)
	PPIH	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (177 aa)
	ENSGGOP00000035693	Pre-mRNA processing factor 19. (524 aa)
	ENSGGOP00000036541	Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (71 aa)
	WBP11	WW domain binding protein 11. (668 aa)
	ENSGGOP00000037236	DUF1716 domain-containing protein. (456 aa)
	ENSGGOP00000037336	Small nuclear ribonucleoprotein-associated protein. (199 aa)
	ENSGGOP00000037523	Uncharacterized protein. (181 aa)
	ZCRB1	Zinc finger CCHC-type and RNA binding motif containing 1. (217 aa)
	DDX42	DEAD-box helicase 42. (938 aa)
	ENSGGOP00000039627	Uncharacterized protein. (556 aa)
	ENSGGOP00000039742	Uncharacterized protein. (489 aa)
	SYF2	SYF2 pre-mRNA splicing factor. (243 aa)
	ENSGGOP00000040319	Sm domain-containing protein. (78 aa)
	ENSGGOP00000041108	PRP38_assoc domain-containing protein. (269 aa)
	ENSGGOP00000041134	RNA binding motif protein 41. (413 aa)
	ENSGGOP00000041470	Splicing factor 3b subunit 1. (1268 aa)
	ENSGGOP00000041513	Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (70 aa)
	ENSGGOP00000042199	Uncharacterized protein. (539 aa)
	DHX38	DEAH-box helicase 38. (1234 aa)
	ENSGGOP00000042442	Uncharacterized protein. (137 aa)
	BUD31	BUD31 homolog. (144 aa)
	PPIL3	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (180 aa)
	TMIGD2	Transmembrane and immunoglobulin domain containing 2. (281 aa)
	ENSGGOP00000045291	LRRcap domain-containing protein. (255 aa)
	ENSGGOP00000045397	RRM domain-containing protein. (415 aa)
	PPIL2	Peptidylprolyl isomerase like 2. (527 aa)
	ENSGGOP00000045752	RRM domain-containing protein. (470 aa)
	PRPF4	Pre-mRNA processing factor 4. (539 aa)
	LSM5	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (91 aa)
	LSM4	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (238 aa)
	SNRPE	Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (92 aa)
	ENSGGOP00000048443	Helicase C-terminal domain-containing protein. (558 aa)
	PRPF18	SFM domain-containing protein. (337 aa)
	CWC27	CWC27 spliceosome associated cyclophilin. (472 aa)
	PPWD1	Peptidylprolyl isomerase domain and WD repeat containing 1. (646 aa)
	CTNNBL1	Catenin beta like 1. (568 aa)
	ENSGGOP00000050193	Sm domain-containing protein. (65 aa)
	PPIG	Peptidylprolyl isomerase G. (752 aa)
	ENSGGOP00000050803	Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (87 aa)
	ENSGGOP00000050913	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (156 aa)
	ENSGGOP00000050996	Uncharacterized protein. (413 aa)
	ENSGGOP00000051589	annotation not available (73 aa)
	LSM2	U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)
	ENSGGOP00000052255	Uncharacterized protein. (87 aa)
	ENSGGOP00000052276	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (156 aa)
	ENSGGOP00000052403	Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (67 aa)

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AQR	BCAS2	ENSGGOP00000013742	ENSGGOP00000020214	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	Uncharacterized protein.	0.863
AQR	BUD13	ENSGGOP00000013742	ENSGGOP00000000652	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	BUD13 homolog.	0.769
AQR	BUD31	ENSGGOP00000013742	ENSGGOP00000043506	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	BUD31 homolog.	0.987
AQR	CACTIN	ENSGGOP00000013742	ENSGGOP00000012221	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	Cactin, spliceosome C complex subunit.	0.760
AQR	CDC40	ENSGGOP00000013742	ENSGGOP00000002414	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	Cell division cycle 40.	0.940
AQR	CDC5L	ENSGGOP00000013742	ENSGGOP00000006644	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	Cell division cycle 5 like.	0.962
AQR	CRNKL1	ENSGGOP00000013742	ENSGGOP00000013833	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	Crooked neck pre-mRNA splicing factor 1.	0.995
AQR	CTNNBL1	ENSGGOP00000013742	ENSGGOP00000050172	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	Catenin beta like 1.	0.760
AQR	CWC15	ENSGGOP00000013742	ENSGGOP00000011636	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	CWC15 spliceosome associated protein homolog.	0.935
AQR	CWC22	ENSGGOP00000013742	ENSGGOP00000025007	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	CWC22 spliceosome associated protein homolog.	0.940
AQR	CWC25	ENSGGOP00000013742	ENSGGOP00000006931	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	CWC25 spliceosome associated protein homolog.	0.783
AQR	CWC27	ENSGGOP00000013742	ENSGGOP00000048552	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	CWC27 spliceosome associated cyclophilin.	0.841
AQR	CWF19L2	ENSGGOP00000013742	ENSGGOP00000000048	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	CWF19 like cell cycle control factor 2.	0.793
AQR	DHX16	ENSGGOP00000013742	ENSGGOP00000019417	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	DEAH-box helicase 16.	0.850
AQR	DHX38	ENSGGOP00000013742	ENSGGOP00000042236	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	DEAH-box helicase 38.	0.791
AQR	DHX8	ENSGGOP00000013742	ENSGGOP00000026993	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	DEAH-box helicase 8.	0.969
AQR	EFTUD2	ENSGGOP00000013742	ENSGGOP00000012672	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	Elongation factor Tu GTP binding domain containing 2.	0.967
AQR	ENSGGOP00000030007	ENSGGOP00000013742	ENSGGOP00000030007	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	Uncharacterized protein.	0.514
AQR	ENSGGOP00000030598	ENSGGOP00000013742	ENSGGOP00000030598	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development.	0.820
AQR	ENSGGOP00000031230	ENSGGOP00000013742	ENSGGOP00000031230	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	Uncharacterized protein.	0.690

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