51 items (Gorilla gorilla) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CNTD2	Cyclin N-terminal domain containing 2; Belongs to the cyclin family. (307 aa)
	CCNB1	Cyclin B1; Belongs to the cyclin family. (433 aa)
	ESPL1	Extra spindle pole bodies like 1, separase. (2120 aa)
	ANLN	Anillin actin binding protein. (1089 aa)
	CENPF	Centromere protein F. (3057 aa)
	RACGAP1	Rac GTPase activating protein 1. (632 aa)
	AURKB	Aurora kinase B; Belongs to the protein kinase superfamily. (344 aa)
	DLGAP5	DLG associated protein 5. (846 aa)
	CEP55	Centrosomal protein 55. (469 aa)
	KIF23	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (960 aa)
	CDKN3	Cyclin-dependent kinase inhibitor 3; May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues. (212 aa)
	CKAP2	Cytoskeleton associated protein 2. (683 aa)
	PBK	PDZ binding kinase. (322 aa)
	MIS18BP1	MIS18 binding protein 1. (1132 aa)
	NCAPD3	Condensin-2 complex subunit D3; Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. (1498 aa)
	KIF20A	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (890 aa)
	CDCA8	Cell division cycle associated 8. (280 aa)
	AURKC	Aurora kinase C; Belongs to the protein kinase superfamily. (309 aa)
	TTK	TTK protein kinase. (856 aa)
	NCAPD2	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1401 aa)
	HMMR	Hyaluronan mediated motility receptor. (747 aa)
	G3R5X1_GORGO	Non-SMC condensin II complex subunit H2. (546 aa)
	G3R860_GORGO	Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1022 aa)
	G3R9L7_GORGO	Uncharacterized protein. (404 aa)
	SMC4	Structural maintenance of chromosomes protein. (1288 aa)
	KIF14	Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1648 aa)
	ARHGAP11A	Rho GTPase activating protein 11A. (1023 aa)
	PTTG1	Securin; Regulatory protein, which plays a central role in chromosome stability, in the p53/TP53 pathway, and DNA repair. Probably acts by blocking the action of key proteins. During the mitosis, it blocks Separase/ESPL1 function, preventing the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes. At the onset of anaphase, it is ubiquitinated, conducting to its destruction and to the liberation of ESPL1. Its function is however not limited to a blocking activity, since it is required to activate ESPL1. Negatively regulates the transcriptional activity a [...] (202 aa)
	CDC20B	Cell division cycle 20B. (519 aa)
	SPAG5	Sperm associated antigen 5. (1198 aa)
	MELK	Non-specific serine/threonine protein kinase. (649 aa)
	KIF4A	Kinesin family member 4A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1232 aa)
	TOP2A	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1531 aa)
	ECT2	Epithelial cell transforming 2. (914 aa)
	PRC1	Protein regulator of cytokinesis 1. (620 aa)
	ASPM	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity). (3476 aa)
	FOXM1	Forkhead box M1. (763 aa)
	NCAPG2	Non-SMC condensin II complex subunit G2. (1156 aa)
	ENSGGOP00000030111	Protein kinase domain-containing protein. (210 aa)
	NCAPG	Non-SMC condensin I complex subunit G. (1055 aa)
	ENSGGOP00000035777	Baculoviral IAP repeat containing 5. (165 aa)
	ENSGGOP00000036645	Uncharacterized protein. (182 aa)
	ENSGGOP00000037757	UBIQUITIN_CONJUGAT_2 domain-containing protein. (167 aa)
	PTTG2	Pituitary tumor-transforming 2. (196 aa)
	ENSGGOP00000039106	PAF domain-containing protein. (115 aa)
	INCENP	Inner centromere protein. (903 aa)
	ENSGGOP00000045424	UBIQUITIN_CONJUGAT_2 domain-containing protein. (164 aa)
	NCAPH	Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. (745 aa)
	SMC2	Structural maintenance of chromosomes protein. (1197 aa)
	ENSGGOP00000048713	Uncharacterized protein. (227 aa)
	ENSGGOP00000049876	annotation not available (227 aa)

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANLN	ASPM	ENSGGOP00000001689	ENSGGOP00000024559	Anillin actin binding protein.	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	0.844
ANLN	AURKB	ENSGGOP00000001689	ENSGGOP00000002820	Anillin actin binding protein.	Aurora kinase B; Belongs to the protein kinase superfamily.	0.670
ANLN	AURKC	ENSGGOP00000001689	ENSGGOP00000007820	Anillin actin binding protein.	Aurora kinase C; Belongs to the protein kinase superfamily.	0.560
ANLN	CCNB1	ENSGGOP00000001689	ENSGGOP00000001503	Anillin actin binding protein.	Cyclin B1; Belongs to the cyclin family.	0.672
ANLN	CDCA8	ENSGGOP00000001689	ENSGGOP00000007551	Anillin actin binding protein.	Cell division cycle associated 8.	0.491
ANLN	CENPF	ENSGGOP00000001689	ENSGGOP00000002339	Anillin actin binding protein.	Centromere protein F.	0.656
ANLN	CEP55	ENSGGOP00000001689	ENSGGOP00000003880	Anillin actin binding protein.	Centrosomal protein 55.	0.878
ANLN	CKAP2	ENSGGOP00000001689	ENSGGOP00000005817	Anillin actin binding protein.	Cytoskeleton associated protein 2.	0.458
ANLN	DLGAP5	ENSGGOP00000001689	ENSGGOP00000003409	Anillin actin binding protein.	DLG associated protein 5.	0.859
ANLN	ECT2	ENSGGOP00000001689	ENSGGOP00000022788	Anillin actin binding protein.	Epithelial cell transforming 2.	0.859
ANLN	ENSGGOP00000035777	ENSGGOP00000001689	ENSGGOP00000035777	Anillin actin binding protein.	Baculoviral IAP repeat containing 5.	0.514
ANLN	ENSGGOP00000037757	ENSGGOP00000001689	ENSGGOP00000037757	Anillin actin binding protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.408
ANLN	ENSGGOP00000045424	ENSGGOP00000001689	ENSGGOP00000045424	Anillin actin binding protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.539
ANLN	ENSGGOP00000048713	ENSGGOP00000001689	ENSGGOP00000048713	Anillin actin binding protein.	Uncharacterized protein.	0.491
ANLN	ENSGGOP00000049876	ENSGGOP00000001689	ENSGGOP00000049876	Anillin actin binding protein.	annotation not available	0.491
ANLN	ESPL1	ENSGGOP00000001689	ENSGGOP00000001579	Anillin actin binding protein.	Extra spindle pole bodies like 1, separase.	0.404
ANLN	G3R860_GORGO	ENSGGOP00000001689	ENSGGOP00000011560	Anillin actin binding protein.	Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.899
ANLN	G3R9L7_GORGO	ENSGGOP00000001689	ENSGGOP00000012102	Anillin actin binding protein.	Uncharacterized protein.	0.515
ANLN	HMMR	ENSGGOP00000001689	ENSGGOP00000009713	Anillin actin binding protein.	Hyaluronan mediated motility receptor.	0.834
ANLN	INCENP	ENSGGOP00000001689	ENSGGOP00000042461	Anillin actin binding protein.	Inner centromere protein.	0.835