STRINGSTRING
KDM1A KDM1A SAP30L SAP30L SAP30 SAP30 RCOR1 RCOR1 HDAC2 HDAC2 AIRE AIRE BRMS1L BRMS1L G3QYI2_GORGO G3QYI2_GORGO MBD3L1 MBD3L1 HMG20A HMG20A RCOR3 RCOR3 SIN3B SIN3B SUDS3 SUDS3 HDAC8 HDAC8 HDAC1 HDAC1 PHF12 PHF12 G3R9K9_GORGO G3R9K9_GORGO ING1 ING1 MBD2 MBD2 CHD3 CHD3 MTA2 MTA2 SINHCAF SINHCAF RCOR2 RCOR2 SAP130 SAP130 ZNF219 ZNF219 CHD4 CHD4 G3RWU1_GORGO G3RWU1_GORGO WDR73 WDR73 ZNF521 ZNF521 ARID4B ARID4B G3SJI3_GORGO G3SJI3_GORGO GATAD1 GATAD1 EMSY EMSY CHD5 CHD5 ARID4A ARID4A ENSGGOP00000033437 ENSGGOP00000033437 HMG20B HMG20B ENSGGOP00000035022 ENSGGOP00000035022 SIN3A SIN3A GATAD2B GATAD2B ENSGGOP00000036571 ENSGGOP00000036571 BRMS1 BRMS1 GSE1 GSE1 MTA3 MTA3 ENSGGOP00000037992 ENSGGOP00000037992 NYNRIN NYNRIN ENSGGOP00000042808 ENSGGOP00000042808 ENSGGOP00000043319 ENSGGOP00000043319 CDK2AP1 CDK2AP1 GATAD2A GATAD2A MTA1 MTA1 ENSGGOP00000049096 ENSGGOP00000049096 ING2 ING2 ENSGGOP00000051084 ENSGGOP00000051084
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (876 aa)
SAP30LSAP30 like. (183 aa)
SAP30Sin3A associated protein 30. (220 aa)
RCOR1REST corepressor 1. (417 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
AIREAutoimmune regulator. (545 aa)
BRMS1LBRMS1 like transcriptional repressor. (323 aa)
G3QYI2_GORGOPHD finger protein 21B. (505 aa)
MBD3L1Methyl-CpG binding domain protein 3 like 1. (194 aa)
HMG20AHigh mobility group 20A. (347 aa)
RCOR3REST corepressor 3. (547 aa)
SIN3BSIN3 transcription regulator family member B. (1153 aa)
SUDS3SDS3 homolog, SIN3A corepressor complex component. (328 aa)
HDAC8Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (377 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
PHF12PHD finger protein 12. (1004 aa)
G3R9K9_GORGOMBD domain-containing protein. (223 aa)
ING1Inhibitor of growth protein. (421 aa)
MBD2Methyl-CpG binding domain protein 2. (411 aa)
CHD3Chromodomain helicase DNA binding protein 3. (2000 aa)
MTA2Metastasis associated 1 family member 2. (673 aa)
SINHCAFUncharacterized protein. (221 aa)
RCOR2REST corepressor 2. (500 aa)
SAP130Sin3A associated protein 130. (1083 aa)
ZNF219Zinc finger protein 219. (718 aa)
CHD4Uncharacterized protein. (1912 aa)
G3RWU1_GORGOUncharacterized protein. (208 aa)
WDR73WD repeat domain 73. (372 aa)
ZNF521Zinc finger protein 521. (1311 aa)
ARID4BAT-rich interaction domain 4B. (1312 aa)
G3SJI3_GORGOUncharacterized protein. (208 aa)
GATAD1GATA zinc finger domain containing 1. (269 aa)
EMSYEMSY transcriptional repressor, BRCA2 interacting. (1337 aa)
CHD5Chromodomain helicase DNA binding protein 5. (1957 aa)
ARID4AAT-rich interaction domain 4A. (1259 aa)
ENSGGOP00000033437Uncharacterized protein. (104 aa)
HMG20BHigh mobility group 20B. (348 aa)
ENSGGOP00000035022Uncharacterized protein. (197 aa)
SIN3AUncharacterized protein. (154 aa)
GATAD2BGATA zinc finger domain containing 2B. (593 aa)
ENSGGOP00000036571Uncharacterized protein. (73 aa)
BRMS1Uncharacterized protein. (377 aa)
GSE1Gse1 coiled-coil protein. (1213 aa)
MTA3Metastasis associated 1 family member 3. (594 aa)
ENSGGOP00000037992PHD finger protein 21A. (680 aa)
NYNRINNYN domain and retroviral integrase containing. (1924 aa)
ENSGGOP00000042808Uncharacterized protein. (189 aa)
ENSGGOP00000043319WD_REPEATS_REGION domain-containing protein. (424 aa)
CDK2AP1Uncharacterized protein. (133 aa)
GATAD2AGATA zinc finger domain containing 2A. (635 aa)
MTA1Metastasis associated 1. (734 aa)
ENSGGOP00000049096WD_REPEATS_REGION domain-containing protein. (395 aa)
ING2Inhibitor of growth protein. (280 aa)
ENSGGOP00000051084WD_REPEATS_REGION domain-containing protein. (400 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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