STRINGSTRING
G3QK95_GORGO G3QK95_GORGO GTF2A1 GTF2A1 POLR2D POLR2D POLR2F POLR2F MNAT1 MNAT1 GTF2H3 GTF2H3 POLR2G POLR2G CDK7 CDK7 GTF2H4 GTF2H4 POLR2A POLR2A ERCC3 ERCC3 POLR2I POLR2I GTF2H1 GTF2H1 GTF2H5 GTF2H5 POLR2C POLR2C POLR2J POLR2J GTF2E2 GTF2E2 GTF2E1 GTF2E1 ENSGGOP00000029268 ENSGGOP00000029268 ENSGGOP00000033816 ENSGGOP00000033816 ENSGGOP00000034792 ENSGGOP00000034792 ENSGGOP00000036704 ENSGGOP00000036704 ENSGGOP00000037296 ENSGGOP00000037296 ENSGGOP00000042610 ENSGGOP00000042610 GTF2A2 GTF2A2 GTF2F1 GTF2F1 CCNH CCNH ERCC2 ERCC2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
G3QK95_GORGODNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (125 aa)
GTF2A1General transcription factor IIA subunit 1. (370 aa)
POLR2DRNA polymerase II subunit D. (142 aa)
POLR2FRNA polymerase II subunit F. (158 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
GTF2H3General transcription factor IIH subunit 3. (308 aa)
POLR2GRNA polymerase II subunit G. (172 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1960 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
GTF2H1General transcription factor IIH subunit 1. (548 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
POLR2CRNA polymerase II subunit C. (275 aa)
POLR2JRNA_pol_L_2 domain-containing protein. (125 aa)
GTF2E2Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (291 aa)
GTF2E1General transcription factor IIE subunit 1. (439 aa)
ENSGGOP00000029268Uncharacterized protein. (93 aa)
ENSGGOP00000033816RNA_pol_L_2 domain-containing protein. (173 aa)
ENSGGOP00000034792Uncharacterized protein. (55 aa)
ENSGGOP00000036704Uncharacterized protein. (58 aa)
ENSGGOP00000037296TFIIF_beta domain-containing protein. (102 aa)
ENSGGOP00000042610Protein kinase domain-containing protein. (322 aa)
GTF2A2Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (517 aa)
CCNHCyclin H; Belongs to the cyclin family. (329 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (810 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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