(6 nodes) Transcription factor TFIIE complex, and Transcription factor TFIIF complex network (Gorilla gorilla)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GTF2A1	General transcription factor IIA subunit 1. (370 aa)
	GTF2E2	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (291 aa)
	GTF2E1	General transcription factor IIE subunit 1. (439 aa)
	ENSGGOP00000037296	TFIIF_beta domain-containing protein. (102 aa)
	GTF2A2	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa)
	GTF2F1	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (517 aa)

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSGGOP00000037296	GTF2A1	ENSGGOP00000037296	ENSGGOP00000003212	TFIIF_beta domain-containing protein.	General transcription factor IIA subunit 1.	0.910
ENSGGOP00000037296	GTF2A2	ENSGGOP00000037296	ENSGGOP00000046117	TFIIF_beta domain-containing protein.	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.	0.770
ENSGGOP00000037296	GTF2E1	ENSGGOP00000037296	ENSGGOP00000021689	TFIIF_beta domain-containing protein.	General transcription factor IIE subunit 1.	0.967
ENSGGOP00000037296	GTF2E2	ENSGGOP00000037296	ENSGGOP00000021323	TFIIF_beta domain-containing protein.	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	0.975
ENSGGOP00000037296	GTF2F1	ENSGGOP00000037296	ENSGGOP00000046119	TFIIF_beta domain-containing protein.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.997
GTF2A1	ENSGGOP00000037296	ENSGGOP00000003212	ENSGGOP00000037296	General transcription factor IIA subunit 1.	TFIIF_beta domain-containing protein.	0.910
GTF2A1	GTF2A2	ENSGGOP00000003212	ENSGGOP00000046117	General transcription factor IIA subunit 1.	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.	0.999
GTF2A1	GTF2E1	ENSGGOP00000003212	ENSGGOP00000021689	General transcription factor IIA subunit 1.	General transcription factor IIE subunit 1.	0.976
GTF2A1	GTF2E2	ENSGGOP00000003212	ENSGGOP00000021323	General transcription factor IIA subunit 1.	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	0.969
GTF2A1	GTF2F1	ENSGGOP00000003212	ENSGGOP00000046119	General transcription factor IIA subunit 1.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.969
GTF2A2	ENSGGOP00000037296	ENSGGOP00000046117	ENSGGOP00000037296	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.	TFIIF_beta domain-containing protein.	0.770
GTF2A2	GTF2A1	ENSGGOP00000046117	ENSGGOP00000003212	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.	General transcription factor IIA subunit 1.	0.999
GTF2A2	GTF2E1	ENSGGOP00000046117	ENSGGOP00000021689	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.	General transcription factor IIE subunit 1.	0.936
GTF2A2	GTF2E2	ENSGGOP00000046117	ENSGGOP00000021323	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	0.961
GTF2A2	GTF2F1	ENSGGOP00000046117	ENSGGOP00000046119	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.930
GTF2E1	ENSGGOP00000037296	ENSGGOP00000021689	ENSGGOP00000037296	General transcription factor IIE subunit 1.	TFIIF_beta domain-containing protein.	0.967
GTF2E1	GTF2A1	ENSGGOP00000021689	ENSGGOP00000003212	General transcription factor IIE subunit 1.	General transcription factor IIA subunit 1.	0.976
GTF2E1	GTF2A2	ENSGGOP00000021689	ENSGGOP00000046117	General transcription factor IIE subunit 1.	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.	0.936
GTF2E1	GTF2E2	ENSGGOP00000021689	ENSGGOP00000021323	General transcription factor IIE subunit 1.	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	0.999
GTF2E1	GTF2F1	ENSGGOP00000021689	ENSGGOP00000046119	General transcription factor IIE subunit 1.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.992