STRINGSTRING
G3QCX1_GORGO G3QCX1_GORGO G3QD11_GORGO G3QD11_GORGO CLEC9A CLEC9A MPPE1 MPPE1 ZBTB16 ZBTB16 FOS FOS RORA RORA G3QE83_GORGO G3QE83_GORGO G3QEI8_GORGO G3QEI8_GORGO G3QF38_GORGO G3QF38_GORGO CTCF CTCF MAFB MAFB NFIL3 NFIL3 ESRRA ESRRA MYB MYB G3QGG8_GORGO G3QGG8_GORGO G3QH29_GORGO G3QH29_GORGO DDIT3 DDIT3 MYOG MYOG TBX21 TBX21 BATF BATF CRY2 CRY2 ETS1 ETS1 ESR2 ESR2 NFE2 NFE2 RARA RARA FOXO3 FOXO3 PAX5 PAX5 MYF5 MYF5 MYF6 MYF6 DLX5 DLX5 PER2 PER2 ZBTB46 ZBTB46 HERPUD1 HERPUD1 TCF21 TCF21 NR1H2 NR1H2 CLOCK CLOCK PER1 PER1 PASD1 PASD1 CREBBP CREBBP HLF HLF GATA2 GATA2 GATA3 GATA3 NPAS2 NPAS2 SPI1 SPI1 SPIB SPIB FBXL3 FBXL3 CEBPE CEBPE TBL1X TBL1X TRIB3 TRIB3 CEBPD CEBPD FOXO1 FOXO1 TCF12 TCF12 EP300 EP300 ID3 ID3 NR1H3 NR1H3 NPAS4 NPAS4 TGS1 TGS1 ESM1 ESM1 MSX1 MSX1 FOSL2 FOSL2 PPARGC1B PPARGC1B TBL1XR1 TBL1XR1 NR1D1 NR1D1 ESR1 ESR1 PPARGC1A PPARGC1A RXRB RXRB ATF4 ATF4 SIRT1 SIRT1 PRMT8 PRMT8 NCOA1 NCOA1 FOSL1 FOSL1 G3R740_GORGO G3R740_GORGO SETD7 SETD7 RORB RORB ZFHX3 ZFHX3 BACH2 BACH2 NPAS1 NPAS1 IRF1 IRF1 MAFK MAFK ATF3 ATF3 G3RGS2_GORGO G3RGS2_GORGO ETS2 ETS2 BHLHE41 BHLHE41 BHLHE40 BHLHE40 ID1 ID1 HDAC3 HDAC3 IRF2 IRF2 KCNH6 KCNH6 NEUROD1 NEUROD1 GATA1 GATA1 BATF2 BATF2 HDAC5 HDAC5 NCOA3 NCOA3 G3RWH6_GORGO G3RWH6_GORGO KLF5 KLF5 BGLAP BGLAP FOSB FOSB ARL4C ARL4C RUNX3 RUNX3 MYOD1 MYOD1 LMO1 LMO1 IRF8 IRF8 NCOA2 NCOA2 G3S778_GORGO G3S778_GORGO RXRG RXRG G3S843_GORGO G3S843_GORGO RARB RARB DLX6 DLX6 HDAC9 HDAC9 G3S905_GORGO G3S905_GORGO LYL1 LYL1 PGR PGR MSX2 MSX2 CRY1 CRY1 G3SBF3_GORGO G3SBF3_GORGO AHRR AHRR MEF2A MEF2A MEF2B MEF2B HDAC4 HDAC4 MEF2D MEF2D MAFG MAFG ENSGGOP00000028878 ENSGGOP00000028878 TCF4 TCF4 PAX8 PAX8 ARNTL2 ARNTL2 ABCA1 ABCA1 ENSGGOP00000031261 ENSGGOP00000031261 ENSGGOP00000032087 ENSGGOP00000032087 ABCG1 ABCG1 PPARG PPARG ENSGGOP00000032619 ENSGGOP00000032619 ENSGGOP00000032627 ENSGGOP00000032627 ENSGGOP00000033016 ENSGGOP00000033016 PRMT1 PRMT1 ENSGGOP00000033459 ENSGGOP00000033459 ENSGGOP00000033934 ENSGGOP00000033934 TAL1 TAL1 RUNX1 RUNX1 BATF3 BATF3 NKX3-2 NKX3-2 LMO2 LMO2 ENSGGOP00000036695 ENSGGOP00000036695 ARNTL ARNTL JDP2 JDP2 CEBPA CEBPA ENSGGOP00000038558 ENSGGOP00000038558 ENSGGOP00000038823 ENSGGOP00000038823 NFE2L1 NFE2L1 PPARA PPARA RXRA RXRA ENSGGOP00000041335 ENSGGOP00000041335 ENSGGOP00000043083 ENSGGOP00000043083 ENSGGOP00000043685 ENSGGOP00000043685 CEBPG CEBPG CEBPB CEBPB RORC RORC ERG ERG JUNB JUNB FLI1 FLI1 TEF TEF BACH1 BACH1 IRF4 IRF4 ESRRG ESRRG CBFB CBFB NR1D2 NR1D2 ARNT2 ARNT2 RUNX2 RUNX2 RUNX1T1 RUNX1T1 NRIP1 NRIP1 SREBF1 SREBF1 RARG RARG LDB2 LDB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
G3QCX1_GORGOCasein kinase 1 delta; Belongs to the protein kinase superfamily. (427 aa)
G3QD11_GORGOGrowth regulating estrogen receptor binding 1. (1732 aa)
CLEC9AC-type lectin domain containing 9A. (241 aa)
MPPE1Metallophosphoesterase 1. (396 aa)
ZBTB16Zinc finger and BTB domain containing 16. (673 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
RORARAR related orphan receptor A. (555 aa)
G3QE83_GORGOPeriod circadian regulator 3. (1074 aa)
G3QEI8_GORGOCoactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (574 aa)
G3QF38_GORGOForkhead box P3. (441 aa)
CTCFCCCTC-binding factor. (727 aa)
MAFBMAF bZIP transcription factor B. (323 aa)
NFIL3Nuclear factor interleukin-3-regulated protein; Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor (ATF) sites. Represses promoter activity in osteoblasts. Represses transcriptional activity of PER1. Represses transcriptional activity of PER2 via the B-site on the promoter. Activates transcription from the interleukin-3 promoter in T- cells. Competes for the same consensus-binding site with PAR DNA- bi [...] (462 aa)
ESRRAEstrogen related receptor alpha. (422 aa)
MYBMYB proto-oncogene, transcription factor. (761 aa)
G3QGG8_GORGOD-box binding PAR bZIP transcription factor. (325 aa)
G3QH29_GORGOG protein pathway suppressor 2. (327 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa)
MYOGMyogenin. (249 aa)
TBX21T-box transcription factor 21. (535 aa)
BATFBasic leucine zipper ATF-like transcription factor. (125 aa)
CRY2Cryptochrome circadian regulator 2. (614 aa)
ETS1ETS proto-oncogene 1, transcription factor. (485 aa)
ESR2Estrogen receptor 2. (530 aa)
NFE2Nuclear factor, erythroid 2. (373 aa)
RARAUncharacterized protein. (624 aa)
FOXO3Forkhead box O3. (674 aa)
PAX5Paired box 5. (396 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
MYF6Myogenic factor 6. (242 aa)
DLX5Distal-less homeobox 5. (289 aa)
PER2Period circadian regulator 2. (1255 aa)
ZBTB46Zinc finger and BTB domain containing 46. (589 aa)
HERPUD1Homocysteine inducible ER protein with ubiquitin like domain 1. (391 aa)
TCF21Transcription factor 21. (179 aa)
NR1H2Nuclear receptor subfamily 1 group H member 2. (461 aa)
CLOCKClock circadian regulator. (847 aa)
PER1Period circadian regulator 1. (1290 aa)
PASD1PAS domain containing repressor 1. (770 aa)
CREBBPCREB binding protein. (2436 aa)
HLFHLF transcription factor, PAR bZIP family member. (295 aa)
GATA2GATA binding protein 2. (480 aa)
GATA3GATA binding protein 3. (444 aa)
NPAS2Neuronal PAS domain protein 2. (824 aa)
SPI1Spi-1 proto-oncogene. (271 aa)
SPIBETS domain-containing protein. (263 aa)
FBXL3F-box and leucine rich repeat protein 3. (428 aa)
CEBPECCAAT/enhancer-binding protein. (281 aa)
TBL1XTransducin beta like 1 X-linked. (577 aa)
TRIB3Tribbles pseudokinase 3. (385 aa)
CEBPDCCAAT/enhancer-binding protein. (269 aa)
FOXO1Forkhead box O1. (655 aa)
TCF12Transcription factor 12. (706 aa)
EP300E1A binding protein p300. (2416 aa)
ID3Inhibitor of DNA binding 3, HLH protein. (119 aa)
NR1H3Nuclear receptor subfamily 1 group H member 3. (453 aa)
NPAS4Neuronal PAS domain protein 4. (802 aa)
TGS1Trimethylguanosine synthase 1. (855 aa)
ESM1Endothelial cell specific molecule 1. (184 aa)
MSX1Msh homeobox 1. (303 aa)
FOSL2FOS like 2, AP-1 transcription factor subunit. (327 aa)
PPARGC1BPPARG coactivator 1 beta. (997 aa)
TBL1XR1Transducin beta like 1 X-linked receptor 1. (514 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (614 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
PPARGC1APPARG coactivator 1 alpha. (798 aa)
RXRBRetinoid X receptor beta. (537 aa)
ATF4Activating transcription factor 4. (351 aa)
SIRT1Sirtuin 1. (751 aa)
PRMT8Protein arginine methyltransferase 8; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (394 aa)
NCOA1Nuclear receptor coactivator. (1441 aa)
FOSL1FOS like 1, AP-1 transcription factor subunit. (271 aa)
G3R740_GORGOBZIP domain-containing protein; Belongs to the bZIP family. (311 aa)
SETD7Histone-lysine N-methyltransferase SETD7; Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes. (366 aa)
RORBRAR related orphan receptor B. (482 aa)
ZFHX3Zinc finger homeobox 3. (3622 aa)
BACH2BTB domain and CNC homolog 2. (841 aa)
NPAS1Neuronal PAS domain protein 1. (590 aa)
IRF1Interferon regulatory factor. (325 aa)
MAFKMAF bZIP transcription factor K. (157 aa)
ATF3Activating transcription factor 3. (181 aa)
G3RGS2_GORGOCyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (483 aa)
ETS2Protein C-ets-2; Transcription factor; Belongs to the ETS family. (469 aa)
BHLHE41Basic helix-loop-helix family member e41. (419 aa)
BHLHE40Basic helix-loop-helix family member e40. (412 aa)
ID1Inhibitor of DNA binding 1, HLH protein. (155 aa)
HDAC3Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
IRF2Interferon regulatory factor. (349 aa)
KCNH6Potassium voltage-gated channel subfamily H member 6. (994 aa)
NEUROD1Neurogenic differentiation factor. (356 aa)
GATA1GATA binding protein 1. (413 aa)
BATF2Basic leucine zipper ATF-like transcription factor 2. (274 aa)
HDAC5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1122 aa)
NCOA3Nuclear receptor coactivator. (1421 aa)
G3RWH6_GORGOTranscription factor 3. (673 aa)
KLF5Kruppel like factor 5. (457 aa)
BGLAPOsteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. (100 aa)
FOSBFosB proto-oncogene, AP-1 transcription factor subunit. (338 aa)
ARL4CADP ribosylation factor like GTPase 4C; Belongs to the small GTPase superfamily. Arf family. (201 aa)
RUNX3Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (428 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (320 aa)
LMO1LIM domain only 1. (156 aa)
IRF8Interferon regulatory factor 8. (426 aa)
NCOA2Nuclear receptor coactivator. (1464 aa)
G3S778_GORGOFork-head domain-containing protein. (417 aa)
RXRGRetinoid X receptor gamma. (463 aa)
G3S843_GORGOBZIP domain-containing protein. (215 aa)
RARBRetinoic acid receptor beta. (448 aa)
DLX6Distal-less homeobox 6. (292 aa)
HDAC9Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1066 aa)
G3S905_GORGOUncharacterized protein. (134 aa)
LYL1LYL1 basic helix-loop-helix family member. (280 aa)
PGRProgesterone receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcriptional activator of several progesteron-dependent promoters in a variety of cell types. Involved in activation of SRC-dependent MAPK signaling on hormone stimulation. (933 aa)
MSX2Homeobox protein MSX-2; Acts as a transcriptional regulator in bone development. Represses the ALPL promoter activity and antagonizes the stimulatory effect of DLX5 on ALPL expression during osteoblast differentiation. Probable morphogenetic role. May play a role in limb-pattern formation. In osteoblasts, suppresses transcription driven by the osteocalcin FGF response element (OCFRE). Binds to the homeodomain-response element of the ALPL promoter (By similarity). (267 aa)
CRY1Cryptochrome circadian regulator 1. (623 aa)
G3SBF3_GORGOMAF bZIP transcription factor F. (164 aa)
AHRRUncharacterized protein. (718 aa)
MEF2AMyocyte enhancer factor 2A. (504 aa)
MEF2BMyocyte enhancer factor 2B. (368 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1089 aa)
MEF2DMyocyte enhancer factor 2D. (521 aa)
MAFGMAF bZIP transcription factor G. (162 aa)
ENSGGOP00000028878Forkhead box O4. (505 aa)
TCF4Transcription factor 4. (773 aa)
PAX8Paired domain-containing protein. (457 aa)
ARNTL2Aryl hydrocarbon receptor nuclear translocator like 2. (636 aa)
ABCA1ATP binding cassette subfamily A member 1. (2264 aa)
ENSGGOP00000031261Myocyte enhancer factor 2C. (483 aa)
ENSGGOP00000032087BZIP domain-containing protein. (342 aa)
ABCG1ABC transporter domain-containing protein. (810 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
ENSGGOP00000032619cAMP responsive element binding protein 1. (341 aa)
ENSGGOP00000032627Uncharacterized protein. (118 aa)
ENSGGOP00000033016Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (419 aa)
PRMT1Methyltransf_25 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (374 aa)
ENSGGOP00000033459BZIP domain-containing protein. (350 aa)
ENSGGOP00000033934Uncharacterized protein. (318 aa)
TAL1TAL bHLH transcription factor 1, erythroid differentiation factor. (331 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa)
BATF3Basic leucine zipper ATF-like transcription factor 3. (120 aa)
NKX3-2NK3 homeobox 2. (337 aa)
LMO2LIM domain only 2. (222 aa)
ENSGGOP00000036695Uncharacterized protein. (366 aa)
ARNTLAryl hydrocarbon receptor nuclear translocator like. (628 aa)
JDP2Jun dimerization protein 2. (175 aa)
CEBPABZIP domain-containing protein. (141 aa)
ENSGGOP00000038558annotation not available (282 aa)
ENSGGOP00000038823Nuclear receptor corepressor 1. (2386 aa)
NFE2L1Nuclear factor, erythroid 2 like 1. (772 aa)
PPARAPeroxisome proliferator activated receptor alpha. (468 aa)
RXRARetinoid X receptor alpha. (463 aa)
ENSGGOP00000041335Uncharacterized protein. (158 aa)
ENSGGOP00000043083Nuclear receptor corepressor 2. (2519 aa)
ENSGGOP00000043685Homeobox domain-containing protein. (256 aa)
CEBPGCCAAT enhancer binding protein gamma. (150 aa)
CEBPBCCAAT/enhancer-binding protein. (345 aa)
RORCRAR related orphan receptor C. (521 aa)
ERGETS transcription factor ERG. (486 aa)
JUNBJunB proto-oncogene, AP-1 transcription factor subunit. (347 aa)
FLI1Fli-1 proto-oncogene, ETS transcription factor. (452 aa)
TEFTEF transcription factor, PAR bZIP family member. (303 aa)
BACH1BTB domain and CNC homolog 1. (736 aa)
IRF4Interferon regulatory factor 4. (451 aa)
ESRRGEstrogen related receptor gamma. (470 aa)
CBFBCore-binding factor subunit beta. (182 aa)
NR1D2Nuclear receptor subfamily 1 group D member 2. (580 aa)
ARNT2Uncharacterized protein. (759 aa)
RUNX2Runt domain-containing protein. (541 aa)
RUNX1T1RUNX1 partner transcriptional co-repressor 1. (663 aa)
NRIP1Nuclear receptor interacting protein 1. (1158 aa)
SREBF1Sterol regulatory element binding transcription factor 1. (1177 aa)
RARGRetinoic acid receptor gamma. (451 aa)
LDB2LIM domain binding 2. (373 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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