23 items (Gorilla gorilla) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ZBTB16	Zinc finger and BTB domain containing 16. (673 aa)
	G3QH29_GORGO	G protein pathway suppressor 2. (327 aa)
	RARA	Uncharacterized protein. (624 aa)
	NR1H2	Nuclear receptor subfamily 1 group H member 2. (461 aa)
	TBL1X	Transducin beta like 1 X-linked. (577 aa)
	NR1H3	Nuclear receptor subfamily 1 group H member 3. (453 aa)
	TGS1	Trimethylguanosine synthase 1. (855 aa)
	TBL1XR1	Transducin beta like 1 X-linked receptor 1. (514 aa)
	RXRB	Retinoid X receptor beta. (537 aa)
	HDAC3	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
	RXRG	Retinoid X receptor gamma. (463 aa)
	RARB	Retinoic acid receptor beta. (448 aa)
	G3S905_GORGO	Uncharacterized protein. (134 aa)
	PAX8	Paired domain-containing protein. (457 aa)
	ABCA1	ATP binding cassette subfamily A member 1. (2264 aa)
	ABCG1	ABC transporter domain-containing protein. (810 aa)
	PPARG	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
	CEBPA	BZIP domain-containing protein. (141 aa)
	ENSGGOP00000038823	Nuclear receptor corepressor 1. (2386 aa)
	RXRA	Retinoid X receptor alpha. (463 aa)
	ENSGGOP00000043083	Nuclear receptor corepressor 2. (2519 aa)
	RUNX1T1	RUNX1 partner transcriptional co-repressor 1. (663 aa)
	RARG	Retinoic acid receptor gamma. (451 aa)

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCA1	NR1H2	ENSGGOP00000031163	ENSGGOP00000005489	ATP binding cassette subfamily A member 1.	Nuclear receptor subfamily 1 group H member 2.	0.969
ABCA1	NR1H3	ENSGGOP00000031163	ENSGGOP00000008392	ATP binding cassette subfamily A member 1.	Nuclear receptor subfamily 1 group H member 3.	0.831
ABCA1	PPARG	ENSGGOP00000031163	ENSGGOP00000032598	ATP binding cassette subfamily A member 1.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.708
ABCA1	RXRA	ENSGGOP00000031163	ENSGGOP00000041308	ATP binding cassette subfamily A member 1.	Retinoid X receptor alpha.	0.912
ABCA1	RXRB	ENSGGOP00000031163	ENSGGOP00000009599	ATP binding cassette subfamily A member 1.	Retinoid X receptor beta.	0.440
ABCA1	RXRG	ENSGGOP00000031163	ENSGGOP00000024205	ATP binding cassette subfamily A member 1.	Retinoid X receptor gamma.	0.484
ABCG1	G3QH29_GORGO	ENSGGOP00000032150	ENSGGOP00000001647	ABC transporter domain-containing protein.	G protein pathway suppressor 2.	0.428
ABCG1	G3S905_GORGO	ENSGGOP00000032150	ENSGGOP00000024569	ABC transporter domain-containing protein.	Uncharacterized protein.	0.428
ABCG1	NR1H2	ENSGGOP00000032150	ENSGGOP00000005489	ABC transporter domain-containing protein.	Nuclear receptor subfamily 1 group H member 2.	0.695
ABCG1	NR1H3	ENSGGOP00000032150	ENSGGOP00000008392	ABC transporter domain-containing protein.	Nuclear receptor subfamily 1 group H member 3.	0.766
ABCG1	PPARG	ENSGGOP00000032150	ENSGGOP00000032598	ABC transporter domain-containing protein.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.614
ABCG1	RXRA	ENSGGOP00000032150	ENSGGOP00000041308	ABC transporter domain-containing protein.	Retinoid X receptor alpha.	0.607
CEBPA	ENSGGOP00000038823	ENSGGOP00000038288	ENSGGOP00000038823	BZIP domain-containing protein.	Nuclear receptor corepressor 1.	0.562
CEBPA	HDAC3	ENSGGOP00000038288	ENSGGOP00000015976	BZIP domain-containing protein.	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.408
CEBPA	PPARG	ENSGGOP00000038288	ENSGGOP00000032598	BZIP domain-containing protein.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.912
CEBPA	RARA	ENSGGOP00000038288	ENSGGOP00000003063	BZIP domain-containing protein.	Uncharacterized protein.	0.691
CEBPA	RUNX1T1	ENSGGOP00000038288	ENSGGOP00000050466	BZIP domain-containing protein.	RUNX1 partner transcriptional co-repressor 1.	0.945
CEBPA	RXRA	ENSGGOP00000038288	ENSGGOP00000041308	BZIP domain-containing protein.	Retinoid X receptor alpha.	0.537
ENSGGOP00000038823	CEBPA	ENSGGOP00000038823	ENSGGOP00000038288	Nuclear receptor corepressor 1.	BZIP domain-containing protein.	0.562
ENSGGOP00000038823	ENSGGOP00000043083	ENSGGOP00000038823	ENSGGOP00000043083	Nuclear receptor corepressor 1.	Nuclear receptor corepressor 2.	0.982