(11 nodes) Retinoic acid receptor signaling pathway, and Negative regulation of cholesterol storage network (Gorilla gorilla)

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second shell of interactors

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Your Input:
	NR1H2	Nuclear receptor subfamily 1 group H member 2. (461 aa)
	NR1H3	Nuclear receptor subfamily 1 group H member 3. (453 aa)
	RXRB	Retinoid X receptor beta. (537 aa)
	RXRG	Retinoid X receptor gamma. (463 aa)
	RARB	Retinoic acid receptor beta. (448 aa)
	PAX8	Paired domain-containing protein. (457 aa)
	ABCA1	ATP binding cassette subfamily A member 1. (2264 aa)
	ABCG1	ABC transporter domain-containing protein. (810 aa)
	PPARG	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
	RXRA	Retinoid X receptor alpha. (463 aa)
	RARG	Retinoic acid receptor gamma. (451 aa)

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCA1	NR1H2	ENSGGOP00000031163	ENSGGOP00000005489	ATP binding cassette subfamily A member 1.	Nuclear receptor subfamily 1 group H member 2.	0.969
ABCA1	NR1H3	ENSGGOP00000031163	ENSGGOP00000008392	ATP binding cassette subfamily A member 1.	Nuclear receptor subfamily 1 group H member 3.	0.831
ABCA1	PPARG	ENSGGOP00000031163	ENSGGOP00000032598	ATP binding cassette subfamily A member 1.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.708
ABCA1	RXRA	ENSGGOP00000031163	ENSGGOP00000041308	ATP binding cassette subfamily A member 1.	Retinoid X receptor alpha.	0.912
ABCA1	RXRB	ENSGGOP00000031163	ENSGGOP00000009599	ATP binding cassette subfamily A member 1.	Retinoid X receptor beta.	0.440
ABCA1	RXRG	ENSGGOP00000031163	ENSGGOP00000024205	ATP binding cassette subfamily A member 1.	Retinoid X receptor gamma.	0.484
ABCG1	NR1H2	ENSGGOP00000032150	ENSGGOP00000005489	ABC transporter domain-containing protein.	Nuclear receptor subfamily 1 group H member 2.	0.695
ABCG1	NR1H3	ENSGGOP00000032150	ENSGGOP00000008392	ABC transporter domain-containing protein.	Nuclear receptor subfamily 1 group H member 3.	0.766
ABCG1	PPARG	ENSGGOP00000032150	ENSGGOP00000032598	ABC transporter domain-containing protein.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.614
ABCG1	RXRA	ENSGGOP00000032150	ENSGGOP00000041308	ABC transporter domain-containing protein.	Retinoid X receptor alpha.	0.607
NR1H2	ABCA1	ENSGGOP00000005489	ENSGGOP00000031163	Nuclear receptor subfamily 1 group H member 2.	ATP binding cassette subfamily A member 1.	0.969
NR1H2	ABCG1	ENSGGOP00000005489	ENSGGOP00000032150	Nuclear receptor subfamily 1 group H member 2.	ABC transporter domain-containing protein.	0.695
NR1H2	NR1H3	ENSGGOP00000005489	ENSGGOP00000008392	Nuclear receptor subfamily 1 group H member 2.	Nuclear receptor subfamily 1 group H member 3.	0.934
NR1H2	PPARG	ENSGGOP00000005489	ENSGGOP00000032598	Nuclear receptor subfamily 1 group H member 2.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.408
NR1H2	RXRA	ENSGGOP00000005489	ENSGGOP00000041308	Nuclear receptor subfamily 1 group H member 2.	Retinoid X receptor alpha.	0.987
NR1H2	RXRB	ENSGGOP00000005489	ENSGGOP00000009599	Nuclear receptor subfamily 1 group H member 2.	Retinoid X receptor beta.	0.969
NR1H2	RXRG	ENSGGOP00000005489	ENSGGOP00000024205	Nuclear receptor subfamily 1 group H member 2.	Retinoid X receptor gamma.	0.926
NR1H3	ABCA1	ENSGGOP00000008392	ENSGGOP00000031163	Nuclear receptor subfamily 1 group H member 3.	ATP binding cassette subfamily A member 1.	0.831
NR1H3	ABCG1	ENSGGOP00000008392	ENSGGOP00000032150	Nuclear receptor subfamily 1 group H member 3.	ABC transporter domain-containing protein.	0.766
NR1H3	NR1H2	ENSGGOP00000008392	ENSGGOP00000005489	Nuclear receptor subfamily 1 group H member 3.	Nuclear receptor subfamily 1 group H member 2.	0.934