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G3QF38_GORGO G3QF38_GORGO MYB MYB MYOG MYOG TBX21 TBX21 ETS1 ETS1 PAX5 PAX5 MYF5 MYF5 MYF6 MYF6 GATA2 GATA2 GATA3 GATA3 SPI1 SPI1 TCF12 TCF12 ID3 ID3 ESM1 ESM1 ZFHX3 ZFHX3 ETS2 ETS2 ID1 ID1 NEUROD1 NEUROD1 GATA1 GATA1 HDAC5 HDAC5 G3RWH6_GORGO G3RWH6_GORGO RUNX3 RUNX3 MYOD1 MYOD1 LMO1 LMO1 HDAC9 HDAC9 LYL1 LYL1 MEF2A MEF2A MEF2B MEF2B HDAC4 HDAC4 MEF2D MEF2D TCF4 TCF4 ENSGGOP00000031261 ENSGGOP00000031261 ENSGGOP00000032627 ENSGGOP00000032627 TAL1 TAL1 RUNX1 RUNX1 LMO2 LMO2 ENSGGOP00000041335 ENSGGOP00000041335 FLI1 FLI1 CBFB CBFB LDB2 LDB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
G3QF38_GORGOForkhead box P3. (441 aa)
MYBMYB proto-oncogene, transcription factor. (761 aa)
MYOGMyogenin. (249 aa)
TBX21T-box transcription factor 21. (535 aa)
ETS1ETS proto-oncogene 1, transcription factor. (485 aa)
PAX5Paired box 5. (396 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
MYF6Myogenic factor 6. (242 aa)
GATA2GATA binding protein 2. (480 aa)
GATA3GATA binding protein 3. (444 aa)
SPI1Spi-1 proto-oncogene. (271 aa)
TCF12Transcription factor 12. (706 aa)
ID3Inhibitor of DNA binding 3, HLH protein. (119 aa)
ESM1Endothelial cell specific molecule 1. (184 aa)
ZFHX3Zinc finger homeobox 3. (3622 aa)
ETS2Protein C-ets-2; Transcription factor; Belongs to the ETS family. (469 aa)
ID1Inhibitor of DNA binding 1, HLH protein. (155 aa)
NEUROD1Neurogenic differentiation factor. (356 aa)
GATA1GATA binding protein 1. (413 aa)
HDAC5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1122 aa)
G3RWH6_GORGOTranscription factor 3. (673 aa)
RUNX3Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (428 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (320 aa)
LMO1LIM domain only 1. (156 aa)
HDAC9Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1066 aa)
LYL1LYL1 basic helix-loop-helix family member. (280 aa)
MEF2AMyocyte enhancer factor 2A. (504 aa)
MEF2BMyocyte enhancer factor 2B. (368 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1089 aa)
MEF2DMyocyte enhancer factor 2D. (521 aa)
TCF4Transcription factor 4. (773 aa)
ENSGGOP00000031261Myocyte enhancer factor 2C. (483 aa)
ENSGGOP00000032627Uncharacterized protein. (118 aa)
TAL1TAL bHLH transcription factor 1, erythroid differentiation factor. (331 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa)
LMO2LIM domain only 2. (222 aa)
ENSGGOP00000041335Uncharacterized protein. (158 aa)
FLI1Fli-1 proto-oncogene, ETS transcription factor. (452 aa)
CBFBCore-binding factor subunit beta. (182 aa)
LDB2LIM domain binding 2. (373 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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