STRINGSTRING
ENSGGOP00000044817 ENSGGOP00000044817 ENSGGOP00000051819 ENSGGOP00000051819 LRPPRC LRPPRC NOL6 NOL6 HSPA2 HSPA2 ADD3 ADD3 HORMAD2 HORMAD2 SYCP3 SYCP3 HORMAD1 HORMAD1 G3R3B3_GORGO G3R3B3_GORGO SYN1 SYN1 G3QYE9_GORGO G3QYE9_GORGO BLM BLM HUS1B HUS1B G3QW19_GORGO G3QW19_GORGO NEK2 NEK2 CCNB1IP1 CCNB1IP1 FAM9A FAM9A RAD1 RAD1 STAG2 STAG2 SYCE1 SYCE1 SYCE3 SYCE3 G3QIE9_GORGO G3QIE9_GORGO SHOC1 SHOC1 SUV39H1 SUV39H1 WAPL WAPL RGS12 RGS12 RRS1 RRS1 RNF212 RNF212 G3RRD3_GORGO G3RRD3_GORGO NIFK NIFK RAD21L1 RAD21L1 G3RP17_GORGO G3RP17_GORGO KIFAP3 KIFAP3 CHEK1 CHEK1 TOPBP1 TOPBP1 MLH1 MLH1 CCDC155 CCDC155 REC8 REC8 G3RHR8_GORGO G3RHR8_GORGO G3RED9_GORGO G3RED9_GORGO AGO3 AGO3 SMC4 SMC4 SYCP2L SYCP2L SYCE1L SYCE1L G3RAC7_GORGO G3RAC7_GORGO G3R8P9_GORGO G3R8P9_GORGO RAD21 RAD21 DMC1 DMC1 G3R5X1_GORGO G3R5X1_GORGO PSMC3IP PSMC3IP G3R541_GORGO G3R541_GORGO C14H14orf39 C14H14orf39 BRD4 BRD4 TEX11 TEX11 MEI4 MEI4 SMC2 SMC2 NCAPH NCAPH FAM9C FAM9C SMC1B SMC1B ENSGGOP00000044043 ENSGGOP00000044043 CCDC36 CCDC36 ENSGGOP00000043030 ENSGGOP00000043030 ENSGGOP00000042938 ENSGGOP00000042938 INCENP INCENP SYCP2 SYCP2 RAD9B RAD9B SPEGNB SPEGNB ENSGGOP00000036812 ENSGGOP00000036812 ENSGGOP00000035879 ENSGGOP00000035879 ENSGGOP00000035259 ENSGGOP00000035259 UBE2I UBE2I NCAPG NCAPG SUN2 SUN2 P3H4 P3H4 ENSGGOP00000032803 ENSGGOP00000032803 FKBP6 FKBP6 ENSGGOP00000031463 ENSGGOP00000031463 ENSGGOP00000030111 ENSGGOP00000030111 TTN TTN NCAPG2 NCAPG2 CDX2 CDX2 BRCA2 BRCA2 STAG3 STAG3 SYCE2 SYCE2 BRCA1 BRCA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSGGOP00000044817MutL homolog 3. (1410 aa)
ENSGGOP00000051819Protein kinase domain-containing protein. (421 aa)
LRPPRCPPR_long domain-containing protein. (407 aa)
NOL6Nucleolar protein 6. (1155 aa)
HSPA2Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family. (602 aa)
ADD3Adducin 3. (706 aa)
HORMAD2HORMA domain containing 2. (307 aa)
SYCP3Synaptonemal complex protein 3. (242 aa)
HORMAD1HORMA domain containing 1. (394 aa)
G3R3B3_GORGOCell cycle checkpoint control protein; Belongs to the rad9 family. (383 aa)
SYN1Synapsin I. (705 aa)
G3QYE9_GORGOHistone H2A; Belongs to the histone H2A family. (143 aa)
BLMBLM RecQ like helicase. (1415 aa)
HUS1BCheckpoint protein; Belongs to the HUS1 family. (278 aa)
G3QW19_GORGOUncharacterized protein. (423 aa)
NEK2NIMA related kinase 2. (445 aa)
CCNB1IP1Cyclin B1 interacting protein 1. (277 aa)
FAM9AFamily with sequence similarity 9 member A. (292 aa)
RAD1RAD1 checkpoint DNA exonuclease. (282 aa)
STAG2Stromal antigen 2. (1268 aa)
SYCE1Synaptonemal complex central element protein 1. (351 aa)
SYCE3Synaptonemal complex central element protein 3. (88 aa)
G3QIE9_GORGOUncharacterized protein. (202 aa)
SHOC1Shortage in chiasmata 1. (1408 aa)
SUV39H1Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (423 aa)
WAPLWAPL cohesin release factor. (1190 aa)
RGS12Regulator of G protein signaling 12. (1368 aa)
RRS1Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (365 aa)
RNF212Ring finger protein 212. (297 aa)
G3RRD3_GORGORRM domain-containing protein. (249 aa)
NIFKNucleolar protein interacting with the FHA domain of MKI67. (293 aa)
RAD21L1RAD21 cohesin complex component like 1. (556 aa)
G3RP17_GORGOStructural maintenance of chromosomes protein. (1175 aa)
KIFAP3Kinesin associated protein 3. (792 aa)
CHEK1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (476 aa)
TOPBP1DNA topoisomerase II binding protein 1. (1527 aa)
MLH1MutL homolog 1. (756 aa)
CCDC155Coiled-coil domain containing 155. (562 aa)
REC8REC8 meiotic recombination protein. (547 aa)
G3RHR8_GORGOSynaptonemal complex protein 1. (942 aa)
G3RED9_GORGODNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (340 aa)
AGO3Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (860 aa)
SMC4Structural maintenance of chromosomes protein. (1288 aa)
SYCP2LSynaptonemal complex protein 2 like. (812 aa)
SYCE1LUncharacterized protein. (212 aa)
G3RAC7_GORGOCor1 domain-containing protein. (225 aa)
G3R8P9_GORGORadial spoke head component 1. (343 aa)
RAD21RAD21 cohesin complex component. (631 aa)
DMC1Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (340 aa)
G3R5X1_GORGONon-SMC condensin II complex subunit H2. (546 aa)
PSMC3IPPSMC3 interacting protein. (217 aa)
G3R541_GORGOUncharacterized protein. (146 aa)
C14H14orf39Chromosome 14 open reading frame 39. (587 aa)
BRD4Bromodomain containing 4. (1362 aa)
TEX11Testis expressed 11. (940 aa)
MEI4Meiotic double-stranded break formation protein 4. (385 aa)
SMC2Structural maintenance of chromosomes protein. (1197 aa)
NCAPHCondensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. (745 aa)
FAM9CFamily with sequence similarity 9 member C. (166 aa)
SMC1BStructural maintenance of chromosomes protein. (1235 aa)
ENSGGOP00000044043Uncharacterized protein. (100 aa)
CCDC36Coiled-coil domain containing 36. (595 aa)
ENSGGOP00000043030Serine/threonine-protein kinase PLK. (624 aa)
ENSGGOP00000042938Checkpoint protein; Belongs to the HUS1 family. (273 aa)
INCENPInner centromere protein. (903 aa)
SYCP2Synaptonemal complex protein 2. (1530 aa)
RAD9BCell cycle checkpoint control protein; Belongs to the rad9 family. (429 aa)
SPEGNBSPEG neighbor. (238 aa)
ENSGGOP00000036812HORMA domain-containing protein. (363 aa)
ENSGGOP00000035879RRM domain-containing protein. (251 aa)
ENSGGOP00000035259Structural maintenance of chromosomes 1A. (1096 aa)
UBE2IUbiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
NCAPGNon-SMC condensin I complex subunit G. (1055 aa)
SUN2Sad1 and UNC84 domain containing 2. (717 aa)
P3H4Prolyl 3-hydroxylase family member 4 (non-enzymatic). (437 aa)
ENSGGOP00000032803MutS homolog 4. (844 aa)
FKBP6Peptidylprolyl isomerase. (327 aa)
ENSGGOP00000031463Peptidylprolyl isomerase. (101 aa)
ENSGGOP00000030111Protein kinase domain-containing protein. (210 aa)
TTNTitin. (32000 aa)
NCAPG2Non-SMC condensin II complex subunit G2. (1156 aa)
CDX2Caudal type homeobox 2. (313 aa)
BRCA2BRCA2 DNA repair associated. (3416 aa)
STAG3Stromal antigen 3. (1221 aa)
SYCE2Uncharacterized protein. (126 aa)
BRCA1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1824 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.