STRINGSTRING
G3QF38_GORGO G3QF38_GORGO G3QT76_GORGO G3QT76_GORGO IL1B IL1B NRROS NRROS ADGRG1 ADGRG1 CD2AP CD2AP ITGB6 ITGB6 PCSK5 PCSK5 CMA1 CMA1 COL3A1 COL3A1 IL6 IL6 TLR3 TLR3 ENSGGOP00000046758 ENSGGOP00000046758 ENSGGOP00000045267 ENSGGOP00000045267 ITGAV ITGAV HIF1A HIF1A IL6R IL6R ADAMTS3 ADAMTS3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
G3QF38_GORGOForkhead box P3. (441 aa)
G3QT76_GORGOTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa)
NRROSNegative regulator of reactive oxygen species. (692 aa)
ADGRG1Adhesion G-protein coupled receptor G1; Receptor involved in cell adhesion and probably in cell-cell interactions. Mediates cell matrix adhesion in developing neurons and hematopoietic stem cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basement membrane integrity and in cortical lamination. Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12. Plays a role in the maintenance of hematopoietic stem cells a [...] (693 aa)
CD2APCD2 associated protein. (639 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (788 aa)
PCSK5Proprotein convertase subtilisin/kexin type 5; Belongs to the peptidase S8 family. (1825 aa)
CMA1Chymase 1; Belongs to the peptidase S1 family. (252 aa)
COL3A1Collagen type III alpha 1 chain. (1466 aa)
IL6Interleukin 6. (234 aa)
TLR3Toll-like receptor 3 precursor; Belongs to the Toll-like receptor family. (904 aa)
ENSGGOP00000046758Caspase 1; Belongs to the peptidase C14A family. (404 aa)
ENSGGOP00000045267Uncharacterized protein; Belongs to the peptidase C14A family. (342 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1002 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (850 aa)
IL6RInterleukin 6 receptor. (468 aa)
ADAMTS3ADAM metallopeptidase with thrombospondin type 1 motif 3. (1205 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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