STRINGSTRING
CXCL12 CXCL12 G3RKL3_GORGO G3RKL3_GORGO ARL8B ARL8B NPPB NPPB CCL1 CCL1 SLAMF7 SLAMF7 G3RVS4_GORGO G3RVS4_GORGO G3RXV4_GORGO G3RXV4_GORGO PPBP PPBP CCL20 CCL20 CXCL3 CXCL3 CCL21 CCL21 C3 C3 DEFB118 DEFB118 EMP2 EMP2 CCL22 CCL22 ULBP1 ULBP1 ENSGGOP00000049861 ENSGGOP00000049861 ENSGGOP00000048920 ENSGGOP00000048920 TREM1 TREM1 ENSGGOP00000047246 ENSGGOP00000047246 TAC1 TAC1 ROMO1 ROMO1 ENSGGOP00000046335 ENSGGOP00000046335 NLRP6 NLRP6 CCL11 CCL11 CEBPG CEBPG ENSGGOP00000042713 ENSGGOP00000042713 RPL30 RPL30 KLRF2 KLRF2 CXCL11 CXCL11 ENSGGOP00000037086 ENSGGOP00000037086 FCGR1A FCGR1A ENSGGOP00000033064 ENSGGOP00000033064 HTN3 HTN3 LYST LYST ENSGGOP00000031506 ENSGGOP00000031506 PRDX1 PRDX1 ENSGGOP00000029619 ENSGGOP00000029619 IL7R IL7R SH2D1A SH2D1A HAMP HAMP G3QER9_GORGO G3QER9_GORGO PGLYRP3 PGLYRP3 PGLYRP4 PGLYRP4 G3QF49_GORGO G3QF49_GORGO SCNN1B SCNN1B CCL17 CCL17 PRF1 PRF1 CTSC CTSC LCE3B LCE3B STXBP2 STXBP2 CXCL14 CXCL14 CCL13 CCL13 CCL27 CCL27 LAG3 LAG3 GZMM GZMM CXCL1 CXCL1 LGALS3 LGALS3 POMC POMC MYD88 MYD88 ULBP3 ULBP3 KNG1 KNG1 CCL8 CCL8 DEFA1B DEFA1B CXCL9 CXCL9 HTN1 HTN1 CD2 CD2 CCL25 CCL25 G3QRP1_GORGO G3QRP1_GORGO G3QRT3_GORGO G3QRT3_GORGO DEFB132 DEFB132 S100A12 S100A12 G3QVM2_GORGO G3QVM2_GORGO F2 F2 TUSC2 TUSC2 G3QXJ6_GORGO G3QXJ6_GORGO LTF LTF DCD DCD G3R063_GORGO G3R063_GORGO RAET1E RAET1E G3SK93_GORGO G3SK93_GORGO CHGA CHGA UNC13D UNC13D HPRT1 HPRT1 G3SHW5_GORGO G3SHW5_GORGO PPP3CB PPP3CB G3SET6_GORGO G3SET6_GORGO B2M B2M ENSGGOP00000025483 ENSGGOP00000025483 G3SBD9_GORGO G3SBD9_GORGO G3SBB4_GORGO G3SBB4_GORGO GAPDH GAPDH NTS NTS CXCL10 CXCL10 DEFA4 DEFA4 DEFA6 DEFA6 TOR2A TOR2A LYZ LYZ PGLYRP1 PGLYRP1 CCL18 CCL18 CTSH CTSH CORO1A CORO1A CCL28 CCL28 G3RB29_GORGO G3RB29_GORGO DEFB128 DEFB128 KIF5B KIF5B G3RD46_GORGO G3RD46_GORGO CXCL13 CXCL13 PTPN6 PTPN6 RAB27A RAB27A NKG7 NKG7 PLEKHM2 PLEKHM2 RNF19B RNF19B RPS19 RPS19 PF4 PF4 IL18 IL18 C9 C9 DEFA5 DEFA5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (140 aa)
G3RKL3_GORGOMHC_I-like_Ag-recog domain-containing protein. (393 aa)
ARL8BADP ribosylation factor like GTPase 8B; Belongs to the small GTPase superfamily. Arf family. (186 aa)
NPPBNatriuretic peptide B. (134 aa)
CCL1C-C motif chemokine. (96 aa)
SLAMF7SLAM family member 7. (335 aa)
G3RVS4_GORGOSignal transducer and activator of transcription. (787 aa)
G3RXV4_GORGOUncharacterized protein. (345 aa)
PPBPC-X-C motif chemokine. (128 aa)
CCL20C-C motif chemokine. (96 aa)
CXCL3C-X-C motif chemokine. (107 aa)
CCL21C-C motif chemokine ligand 21. (134 aa)
C3Complement C3. (1663 aa)
DEFB118Beta-defensin 118; Has antibacterial activity; Belongs to the beta-defensin family. (123 aa)
EMP2Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (167 aa)
CCL22C-C motif chemokine. (93 aa)
ULBP1UL16 binding protein 1. (243 aa)
ENSGGOP00000049861Uncharacterized protein; Belongs to the synaptobrevin family. (230 aa)
ENSGGOP00000048920Ribosomal_L7Ae domain-containing protein. (93 aa)
TREM1IG domain-containing protein. (249 aa)
ENSGGOP00000047246annotation not available (97 aa)
TAC1Tachykinin precursor 1. (129 aa)
ROMO1Reactive oxygen species modulator 1. (79 aa)
ENSGGOP00000046335Uncharacterized protein. (118 aa)
NLRP6Uncharacterized protein. (912 aa)
CCL11C-C motif chemokine. (97 aa)
CEBPGCCAAT enhancer binding protein gamma. (150 aa)
ENSGGOP00000042713Uncharacterized protein. (140 aa)
RPL30Ribosomal_L7Ae domain-containing protein. (115 aa)
KLRF2Killer cell lectin like receptor F2. (207 aa)
CXCL11C-X-C motif chemokine. (94 aa)
ENSGGOP00000037086Defensin_propep domain-containing protein; Belongs to the alpha-defensin family. (72 aa)
FCGR1AUncharacterized protein. (374 aa)
ENSGGOP00000033064Uncharacterized protein. (308 aa)
HTN3Histatin 3. (51 aa)
LYSTLysosomal trafficking regulator. (3790 aa)
ENSGGOP00000031506DEFENSIN domain-containing protein. (93 aa)
PRDX1Peroxiredoxin 1. (220 aa)
ENSGGOP00000029619Thioredoxin domain-containing protein. (188 aa)
IL7RInterleukin 7 receptor. (458 aa)
SH2D1ASH2 domain-containing protein 1A; Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2. (128 aa)
HAMPHepcidin antimicrobial peptide. (84 aa)
G3QER9_GORGOElastase, neutrophil expressed; Belongs to the peptidase S1 family. (246 aa)
PGLYRP3Peptidoglycan recognition protein 3. (341 aa)
PGLYRP4Peptidoglycan recognition protein 4. (373 aa)
G3QF49_GORGOAzurocidin 1. (251 aa)
SCNN1BSodium channel epithelial 1 beta subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (685 aa)
CCL17C-C motif chemokine. (94 aa)
PRF1Perforin 1. (555 aa)
CTSCCathepsin C; Belongs to the peptidase C1 family. (463 aa)
LCE3BLate cornified envelope 3B. (95 aa)
STXBP2Syntaxin binding protein 2; Belongs to the STXBP/unc-18/SEC1 family. (652 aa)
CXCL14C-X-C motif chemokine ligand 14. (111 aa)
CCL13C-C motif chemokine. (98 aa)
CCL27SCY domain-containing protein. (112 aa)
LAG3Lymphocyte activating 3. (525 aa)
GZMMGranzyme M; Belongs to the peptidase S1 family. (257 aa)
CXCL1C-X-C motif chemokine. (107 aa)
LGALS3Galectin. (267 aa)
POMCProopiomelanocortin. (267 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is cruc [...] (317 aa)
ULBP3UL16 binding protein 3. (244 aa)
KNG1Kininogen 1. (644 aa)
CCL8C-C motif chemokine. (99 aa)
DEFA1BDEFENSIN domain-containing protein. (94 aa)
CXCL9C-X-C motif chemokine. (125 aa)
HTN1Histatin 1. (57 aa)
CD2CD2 molecule. (351 aa)
CCL25C-C motif chemokine ligand 25. (150 aa)
G3QRP1_GORGOUncharacterized protein. (107 aa)
G3QRT3_GORGOGranulysin. (173 aa)
DEFB132Beta-defensin 132; Has antibacterial activity; Belongs to the beta-defensin family. (94 aa)
S100A12S100 calcium binding protein A12; Belongs to the S-100 family. (92 aa)
G3QVM2_GORGOKiller cell lectin like receptor K1. (216 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (622 aa)
TUSC2Tumor suppressor 2, mitochondrial calcium regulator. (110 aa)
G3QXJ6_GORGOMHC_I-like_Ag-recog domain-containing protein. (241 aa)
LTFLactotransferrin; Belongs to the transferrin family. (711 aa)
DCDDermcidin. (120 aa)
G3R063_GORGOC-X-C motif chemokine. (103 aa)
RAET1EMHC_I-like_Ag-recog domain-containing protein. (263 aa)
G3SK93_GORGOHistone H2B; Belongs to the histone H2B family. (126 aa)
CHGAChromogranin A. (458 aa)
UNC13DUnc-13 homolog D. (1090 aa)
HPRT1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (218 aa)
G3SHW5_GORGOC-type lectin domain-containing protein. (160 aa)
PPP3CBSerine/threonine-protein phosphatase. (524 aa)
G3SET6_GORGOC-X-C motif chemokine. (107 aa)
B2MBeta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). (119 aa)
ENSGGOP00000025483annotation not available (112 aa)
G3SBD9_GORGODEFSN domain-containing protein. (55 aa)
G3SBB4_GORGORibosomal_L7Ae domain-containing protein. (133 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (335 aa)
NTSNeurotensin. (170 aa)
CXCL10C-X-C motif chemokine. (98 aa)
DEFA4Defensin alpha 4. (97 aa)
DEFA6Defensin alpha 6. (100 aa)
TOR2ATorsin. (321 aa)
LYZLysozyme C; Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents; Belongs to the glycosyl hydrolase 22 family. (148 aa)
PGLYRP1Peptidoglycan-recognition protein; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Involved in innate immunity. (196 aa)
CCL18C-C motif chemokine. (89 aa)
CTSHCathepsin H; Belongs to the peptidase C1 family. (335 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (461 aa)
CCL28C-C motif chemokine. (127 aa)
G3RB29_GORGOGranzyme B; Belongs to the peptidase S1 family. (247 aa)
DEFB128Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (92 aa)
KIF5BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (963 aa)
G3RD46_GORGOCathepsin G; Belongs to the peptidase S1 family. (255 aa)
CXCL13C-X-C motif chemokine. (109 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
RAB27ARAB27A, member RAS oncogene family. (221 aa)
NKG7Natural killer cell granule protein 7. (165 aa)
PLEKHM2Pleckstrin homology and RUN domain containing M2. (1015 aa)
RNF19BRBR-type E3 ubiquitin transferase. (545 aa)
RPS19Ribosomal protein S19. (145 aa)
PF4C-X-C motif chemokine. (101 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
C9Complement C9. (559 aa)
DEFA5Defensin alpha 5. (94 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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