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| | CCL24 | SCY domain-containing protein. (64 aa) |
| | FGF7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa) |
| | EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1183 aa) |
| | GDF2 | Growth differentiation factor 2. (429 aa) |
| | G3QT76_GORGO | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | GATA2 | GATA binding protein 2. (480 aa) |
| | G3QU00_GORGO | Uncharacterized protein. (567 aa) |
| | ACVRL1 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa) |
| | FLT4 | Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1319 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (328 aa) |
| | CNMD | Chondromodulin. (334 aa) |
| | COL4A3 | Collagen type IV alpha 3 chain. (1578 aa) |
| | VEGFD | Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (354 aa) |
| | EGR3 | Early growth response 3. (349 aa) |
| | KRIT1 | Uncharacterized protein. (736 aa) |
| | NRP1 | Neuropilin; Belongs to the neuropilin family. (923 aa) |
| | PRL | Prolactin. (227 aa) |
| | FUT1 | Galactoside 2-alpha-L-fucosyltransferase 1; Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Gal-beta-) called the H antigen which is an essential substrate for the final step in the soluble A and B antigen synthesis pathway. Belongs to the glycosyltransferase 11 family. (366 aa) |
| | FUT2 | Galactoside 2-alpha-L-fucosyltransferase 2; Mediates the transfer of fucose to the terminal galactose on glycan chains of cell surface glycoproteins and glycolipids. The resulting epitope plays a role in cell-cell interaction including host- microbe interaction. Mediates interaction with intestinal microbiota influencing its composition. Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen, which is an essential substrate for the final step in the membrane-associated blood group antigen synthesis pathway. (343 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (167 aa) |
| | ENG | Endoglin. (654 aa) |
| | BMP6 | Bone morphogenetic protein 6. (515 aa) |
| | ATP5IF1 | ATP synthase inhibitory factor subunit 1. (106 aa) |
| | IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa) |
| | NF1 | Neurofibromin 1. (2811 aa) |
| | G3QWN1_GORGO | Synaptojanin 2 binding protein. (145 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | ITGB3 | Integrin beta; Belongs to the integrin beta chain family. (837 aa) |
| | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa) |
| | PROK1 | Prokineticin 1. (105 aa) |
| | NGFR | Nerve growth factor receptor. (427 aa) |
| | PDCD10 | Programmed cell death 10. (212 aa) |
| | TIE1 | Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1138 aa) |
| | FLT1 | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1302 aa) |
| | SIRT6 | Sirtuin 6. (355 aa) |
| | MMRN2 | Multimerin 2. (838 aa) |
| | G3R1H9_GORGO | Apolipoprotein H. (286 aa) |
| | NRP2 | Neuropilin; Belongs to the neuropilin family. (926 aa) |
| | GHRL | Ghrelin and obestatin prepropeptide. (117 aa) |
| | SIRT1 | Sirtuin 1. (751 aa) |
| | AGGF1 | Uncharacterized protein. (715 aa) |
| | CCR3 | C-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (376 aa) |
| | SEMA5A | Semaphorin 5A. (1041 aa) |
| | XDH | Xanthine dehydrogenase. (1333 aa) |
| | PRKD1 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (832 aa) |
| | VEGFB | PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (168 aa) |
| | G3R9L0_GORGO | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family. (1072 aa) |
| | G3RA25_GORGO | Sp1 transcription factor. (786 aa) |
| | G3RAC9_GORGO | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (395 aa) |
| | ALOX5 | Arachidonate 5-lipoxygenase. (678 aa) |
| | KDR | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa) |
| | FGFR1 | Fibroblast growth factor receptor. (820 aa) |
| | ADAM17 | ADAM metallopeptidase domain 17. (824 aa) |
| | IL10 | Interleukin 10. (178 aa) |
| | PGF | PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (221 aa) |
| | BMP4 | Bone morphogenetic protein 4. (408 aa) |
| | CAV2 | Caveolin-2; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (B [...] (162 aa) |
| | PROX1 | Prospero homeobox 1. (737 aa) |
| | PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (220 aa) |
| | PPP1R16B | Protein phosphatase 1 regulatory subunit 16B. (568 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa) |
| | TEK | TEK receptor tyrosine kinase. (1124 aa) |
| | DBH | Dopamine beta-hydroxylase. (617 aa) |
| | FGFBP1 | Fibroblast growth factor binding protein 1. (234 aa) |
| | SPARC | Secreted protein acidic and cysteine rich. (303 aa) |
| | CCL2 | C-C motif chemokine. (99 aa) |
| | CXCL12 | C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (140 aa) |
| | TNMD | Tenomodulin. (317 aa) |
| | VASH1 | Vasohibin 1. (365 aa) |
| | G3RLN8_GORGO | Signal transducer and activator of transcription. (652 aa) |
| | G3RR23_GORGO | Uncharacterized protein. (210 aa) |
| | ARG1 | Arginase. (322 aa) |
| | G3RS38_GORGO | Phosducin domain-containing protein. (234 aa) |
| | CDH13 | Cadherin 13. (760 aa) |
| | HTR2B | 5-hydroxytryptamine receptor 2B. (481 aa) |
| | AIMP1 | Aminoacyl tRNA synthetase complex interacting multifunctional protein 1. (321 aa) |
| | RGCC | Regulator of cell cycle. (137 aa) |
| | ECM1 | Uncharacterized protein. (540 aa) |
| | STAT3 | Signal transducer and activator of transcription. (781 aa) |
| | G3RXP9_GORGO | Nuclear receptor subfamily 2 group F member 2. (414 aa) |
| | G3RXW1_GORGO | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (372 aa) |
| | BMP2 | Bone morphogenetic protein 2. (396 aa) |
| | ZNF580 | Zinc finger protein 580. (172 aa) |
| | MDK | Midkine. (143 aa) |
| | CAV1 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (147 aa) |
| | ITGA4 | Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1032 aa) |
| | TBC1D31 | TBC1 domain family member 31. (1067 aa) |
| | VIP | Vasoactive intestinal peptide. (170 aa) |
| | NRARP | NOTCH regulated ankyrin repeat protein. (114 aa) |
| | ENSGGOP00000024523 | annotation not available (408 aa) |
| | LRG1 | Leucine rich alpha-2-glycoprotein 1. (347 aa) |
| | APLNR | Apelin receptor; Belongs to the G-protein coupled receptor 1 family. (380 aa) |
| | PDPK1 | Protein kinase domain-containing protein. (347 aa) |
| | ARNT | Aryl hydrocarbon receptor nuclear translocator. (789 aa) |
| | G3SCD5_GORGO | Vasohibin 2. (355 aa) |
| | THBS4 | Thrombospondin 4. (961 aa) |
| | NR4A1 | Nuclear receptor subfamily 4 group A member 1. (652 aa) |
| | GHSR | Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa) |
| | STAT1 | Signal transducer and activator of transcription. (777 aa) |
| | HIF1A | Hypoxia inducible factor 1 subunit alpha. (850 aa) |
| | DLL4 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa) |
| | ALDH1A2 | Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (534 aa) |
| | ENSGGOP00000031261 | Myocyte enhancer factor 2C. (483 aa) |
| | PPARG | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | ANG | Angiogenin; Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA. Cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs) (By similarity). Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo (By similarity). (147 aa) |
| | APELA | Apelin receptor early endogenous ligand. (54 aa) |
| | PDCL3 | Phosducin like 3. (239 aa) |
| | F3 | Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. (295 aa) |
| | PLXNB3 | Plexin B3. (1932 aa) |
| | BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1042 aa) |
| | TNFSF12 | TNF superfamily member 12; Belongs to the tumor necrosis factor family. (249 aa) |
| | SULF1 | Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (883 aa) |
| | ATP5F1A | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (576 aa) |
| | ENSGGOP00000040217 | Uncharacterized protein. (371 aa) |
| | RPTOR | Regulatory associated protein of MTOR complex 1. (1288 aa) |
| | APLN | Apelin. (77 aa) |
| | ENSGGOP00000042002 | Uncharacterized protein. (476 aa) |
| | CCL11 | C-C motif chemokine. (97 aa) |
| | AGTR1 | Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family. (394 aa) |
| | ENSGGOP00000045937 | Protein tyrosine phosphatase receptor type M. (1379 aa) |
| | HMOX1 | Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (289 aa) |
| | ENSGGOP00000046735 | Non-specific serine/threonine protein kinase. (524 aa) |
| | ENSGGOP00000047246 | annotation not available (97 aa) |
| | JCAD | Junctional cadherin 5 associated. (1359 aa) |
| | IGF2 | Insulin like growth factor 2. (236 aa) |
| | PRKD2 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa) |
| | THBS1 | Thrombospondin 1. (1173 aa) |
| | VEGFC | PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (230 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
