(29 nodes) Endochondral ossification network (Gorilla gorilla)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	COL13A1	Collagen type XIII alpha 1 chain. (717 aa)
	BMP6	Bone morphogenetic protein 6. (515 aa)
	NAB2	NGFI-A binding protein 2. (525 aa)
	PHOSPHO1	Phosphoethanolamine/phosphocholine phosphatase. (267 aa)
	PEX7	Peroxisomal biogenesis factor 7. (323 aa)
	COL2A1	Collagen type II alpha 1 chain. (1487 aa)
	DLX5	Distal-less homeobox 5. (289 aa)
	PHOSPHO2	Phosphatase, orphan 2. (241 aa)
	FGF18	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
	FOXC1	Fork-head domain-containing protein. (210 aa)
	ALPL	Alkaline phosphatase. (524 aa)
	COL1A1	Collagen type I alpha 1 chain. (1464 aa)
	NAB1	NGFI-A binding protein 1. (471 aa)
	BMP4	Bone morphogenetic protein 4. (408 aa)
	IMPAD1	Inositol monophosphatase domain containing 1. (359 aa)
	CBS	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (551 aa)
	ENSGGOP00000024523	annotation not available (408 aa)
	TMEM119	Transmembrane protein 119. (283 aa)
	MEF2D	Myocyte enhancer factor 2D. (521 aa)
	MMP16	Matrix metallopeptidase 16. (607 aa)
	ENSGGOP00000031261	Myocyte enhancer factor 2C. (483 aa)
	ENSGGOP00000032065	Uncharacterized protein. (245 aa)
	MMP13	Matrix metallopeptidase 13. (503 aa)
	INPPL1	Inositol polyphosphate phosphatase like 1. (1253 aa)
	ENSGGOP00000041668	Fibroblast growth factor receptor. (808 aa)
	SMPD3	Uncharacterized protein. (535 aa)
	IFT80	Intraflagellar transport 80. (777 aa)
	MMP14	Matrix metallopeptidase 14. (582 aa)
	RUNX2	Runt domain-containing protein. (541 aa)

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALPL	COL1A1	ENSGGOP00000010448	ENSGGOP00000012899	Alkaline phosphatase.	Collagen type I alpha 1 chain.	0.678
ALPL	COL2A1	ENSGGOP00000010448	ENSGGOP00000004237	Alkaline phosphatase.	Collagen type II alpha 1 chain.	0.446
ALPL	PHOSPHO1	ENSGGOP00000010448	ENSGGOP00000001926	Alkaline phosphatase.	Phosphoethanolamine/phosphocholine phosphatase.	0.629
ALPL	RUNX2	ENSGGOP00000010448	ENSGGOP00000049836	Alkaline phosphatase.	Runt domain-containing protein.	0.746
BMP4	BMP6	ENSGGOP00000014564	ENSGGOP00000000891	Bone morphogenetic protein 4.	Bone morphogenetic protein 6.	0.962
BMP4	DLX5	ENSGGOP00000014564	ENSGGOP00000004313	Bone morphogenetic protein 4.	Distal-less homeobox 5.	0.607
BMP4	FGF18	ENSGGOP00000014564	ENSGGOP00000007070	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.516
BMP4	FOXC1	ENSGGOP00000014564	ENSGGOP00000009053	Bone morphogenetic protein 4.	Fork-head domain-containing protein.	0.459
BMP4	RUNX2	ENSGGOP00000014564	ENSGGOP00000049836	Bone morphogenetic protein 4.	Runt domain-containing protein.	0.709
BMP6	BMP4	ENSGGOP00000000891	ENSGGOP00000014564	Bone morphogenetic protein 6.	Bone morphogenetic protein 4.	0.962
BMP6	ENSGGOP00000024523	ENSGGOP00000000891	ENSGGOP00000024523	Bone morphogenetic protein 6.	annotation not available	0.637
BMP6	RUNX2	ENSGGOP00000000891	ENSGGOP00000049836	Bone morphogenetic protein 6.	Runt domain-containing protein.	0.591
COL1A1	ALPL	ENSGGOP00000012899	ENSGGOP00000010448	Collagen type I alpha 1 chain.	Alkaline phosphatase.	0.678
COL1A1	COL2A1	ENSGGOP00000012899	ENSGGOP00000004237	Collagen type I alpha 1 chain.	Collagen type II alpha 1 chain.	0.786
COL1A1	ENSGGOP00000031261	ENSGGOP00000012899	ENSGGOP00000031261	Collagen type I alpha 1 chain.	Myocyte enhancer factor 2C.	0.434
COL1A1	ENSGGOP00000041668	ENSGGOP00000012899	ENSGGOP00000041668	Collagen type I alpha 1 chain.	Fibroblast growth factor receptor.	0.428
COL1A1	MMP13	ENSGGOP00000012899	ENSGGOP00000034775	Collagen type I alpha 1 chain.	Matrix metallopeptidase 13.	0.549
COL1A1	RUNX2	ENSGGOP00000012899	ENSGGOP00000049836	Collagen type I alpha 1 chain.	Runt domain-containing protein.	0.842
COL2A1	ALPL	ENSGGOP00000004237	ENSGGOP00000010448	Collagen type II alpha 1 chain.	Alkaline phosphatase.	0.446
COL2A1	COL1A1	ENSGGOP00000004237	ENSGGOP00000012899	Collagen type II alpha 1 chain.	Collagen type I alpha 1 chain.	0.786