STRINGSTRING
ENSGGOP00000047763 ENSGGOP00000047763 NFATC2 NFATC2 C1S C1S FYN FYN EP300 EP300 C6 C6 NCKAP1L NCKAP1L ZNFX1 ZNFX1 C8B C8B KHDRBS1 KHDRBS1 CFP CFP RFTN1 RFTN1 RBCK1 RBCK1 FPR3 FPR3 TXK TXK FYB2 FYB2 EIF2B1 EIF2B1 THEMIS2 THEMIS2 ZC3H12A ZC3H12A PIK3CA PIK3CA G3R212_GORGO G3R212_GORGO G3R3G6_GORGO G3R3G6_GORGO C1QC C1QC C1QB C1QB CMKLR1 CMKLR1 G3R3U7_GORGO G3R3U7_GORGO BAX BAX SYK SYK KLHL6 KLHL6 LAX1 LAX1 KLRD1 KLRD1 ABL1 ABL1 NOD2 NOD2 RIPK2 RIPK2 MYO1G MYO1G PRKCB PRKCB EIF2B4 EIF2B4 ZBP1 ZBP1 STK11 STK11 FCHO1 FCHO1 CSK CSK PLPP4 PLPP4 PQBP1 PQBP1 XRCC5 XRCC5 C1RL C1RL THY1 THY1 G3R8E2_GORGO G3R8E2_GORGO G3R8G6_GORGO G3R8G6_GORGO PRKCE PRKCE C4BPB C4BPB C4BPA C4BPA BANK1 BANK1 VAV1 VAV1 PYHIN1 PYHIN1 G3R9L0_GORGO G3R9L0_GORGO G3R9N8_GORGO G3R9N8_GORGO LYN LYN CD79B CD79B SKAP1 SKAP1 BTNL9 BTNL9 BTN3A3 BTN3A3 CFHR4 CFHR4 G3RCR2_GORGO G3RCR2_GORGO G3RD62_GORGO G3RD62_GORGO CD276 CD276 C8A C8A SHB SHB PTPN6 PTPN6 HEXIM1 HEXIM1 AIM2 AIM2 IFI16 IFI16 G3QTD2_GORGO G3QTD2_GORGO MFAP4 MFAP4 CREBBP CREBBP MNDA MNDA FFAR2 FFAR2 TRAF6 TRAF6 G3QSI4_GORGO G3QSI4_GORGO FPR2 FPR2 FPR1 FPR1 PLEKHA1 PLEKHA1 IKBKG IKBKG G3QQ53_GORGO G3QQ53_GORGO SPG21 SPG21 G3QMP2_GORGO G3QMP2_GORGO TOMM70 TOMM70 ITK ITK G3QLR1_GORGO G3QLR1_GORGO KRT1 KRT1 G3QLP1_GORGO G3QLP1_GORGO PSPC1 PSPC1 PRKCD PRKCD PAK1 PAK1 NLRC4 NLRC4 C1QBP C1QBP GATA3 GATA3 CFHR5 CFHR5 C5 C5 G3QIF7_GORGO G3QIF7_GORGO PSEN1 PSEN1 G3QGN8_GORGO G3QGN8_GORGO FYB1 FYB1 MASP1 MASP1 CD38 CD38 NONO NONO TREX1 TREX1 PLD2 PLD2 LCP2 LCP2 CD3E CD3E IKBKB IKBKB PDE4B PDE4B G3QF38_GORGO G3QF38_GORGO COLEC10 COLEC10 G3QWJ4_GORGO G3QWJ4_GORGO ERMAP ERMAP EIF2B5 EIF2B5 HHLA2 HHLA2 G3QXK1_GORGO G3QXK1_GORGO PLCG1 PLCG1 CTLA4 CTLA4 BTN2A1 BTN2A1 C3AR1 C3AR1 CACNB3 CACNB3 CD79A CD79A NFKBID NFKBID TYROBP TYROBP SERPING1 SERPING1 XRCC6 XRCC6 C9 C9 BMX BMX RNF31 RNF31 STING1 STING1 C5AR2 C5AR2 CD19 CD19 CLU CLU G3RLC3_GORGO G3RLC3_GORGO RC3H2 RC3H2 PLA2G6 PLA2G6 PYCARD PYCARD TMEM269 TMEM269 G3RPG3_GORGO G3RPG3_GORGO BLK BLK FCER1G FCER1G G3RPZ9_GORGO G3RPZ9_GORGO SLA2 SLA2 G3RQF4_GORGO G3RQF4_GORGO G3RQR5_GORGO G3RQR5_GORGO CD247 CD247 SRC SRC TEC TEC CFH CFH G3RS61_GORGO G3RS61_GORGO VTCN1 VTCN1 NR4A3 NR4A3 MASP2 MASP2 G3RV54_GORGO G3RV54_GORGO G3RVM4_GORGO G3RVM4_GORGO LIMK1 LIMK1 G3RVT8_GORGO G3RVT8_GORGO RGCC RGCC MALT1 MALT1 G3RXL1_GORGO G3RXL1_GORGO MAP3K7 MAP3K7 CD55 CD55 NFKBIZ NFKBIZ SFPQ SFPQ PRAM1 PRAM1 PTK2 PTK2 SUSD4 SUSD4 TRIM5 TRIM5 G3S3W8_GORGO G3S3W8_GORGO G3S7D0_GORGO G3S7D0_GORGO G3S7P9_GORGO G3S7P9_GORGO TBK1 TBK1 YES1 YES1 CLEC6A CLEC6A C3 C3 BTK BTK BRAF BRAF BTN1A1 BTN1A1 CGAS CGAS BLNK BLNK VAV2 VAV2 CD3G CD3G CFB CFB G3SHX6_GORGO G3SHX6_GORGO FCN2 FCN2 PLCG2 PLCG2 G3SIR7_GORGO G3SIR7_GORGO HCK HCK C8G C8G CASP6 CASP6 LAT2 LAT2 ENSGGOP00000029367 ENSGGOP00000029367 ENSGGOP00000030108 ENSGGOP00000030108 MS4A1 MS4A1 ADA ADA CD28 CD28 ENSGGOP00000031261 ENSGGOP00000031261 VSIG4 VSIG4 LCK LCK PAK2 PAK2 ENSGGOP00000032596 ENSGGOP00000032596 ENSGGOP00000032772 ENSGGOP00000032772 GPLD1 GPLD1 ENSGGOP00000032880 ENSGGOP00000032880 ENSGGOP00000033427 ENSGGOP00000033427 ENSGGOP00000033674 ENSGGOP00000033674 UBE2N UBE2N CD3D CD3D ENSGGOP00000035349 ENSGGOP00000035349 SIN3A SIN3A ENSGGOP00000035952 ENSGGOP00000035952 SPPL3 SPPL3 COLEC11 COLEC11 ENSGGOP00000037423 ENSGGOP00000037423 ENSGGOP00000037735 ENSGGOP00000037735 ENSGGOP00000037798 ENSGGOP00000037798 C1R C1R C5AR1 C5AR1 PDE4D PDE4D ENSGGOP00000038632 ENSGGOP00000038632 CRKL CRKL STOML2 STOML2 HRAS HRAS ENSGGOP00000039368 ENSGGOP00000039368 MBL2 MBL2 ENSGGOP00000039847 ENSGGOP00000039847 ENSGGOP00000040139 ENSGGOP00000040139 BAG6 BAG6 MAPK1 MAPK1 TNFRSF21 TNFRSF21 ENSGGOP00000041462 ENSGGOP00000041462 MOG MOG CACNB4 CACNB4 ENSGGOP00000042007 ENSGGOP00000042007 BCL2 BCL2 FGR FGR INPP5D INPP5D EIF2B2 EIF2B2 EIF2B3 EIF2B3 CD46 CD46 FCN3 FCN3 BCAR1 BCAR1 ENSGGOP00000051997 ENSGGOP00000051997 ENSGGOP00000051962 ENSGGOP00000051962 CD8A CD8A BTN3A1 BTN3A1 ENSGGOP00000051678 ENSGGOP00000051678 BCL10 BCL10 ENSGGOP00000050852 ENSGGOP00000050852 NFAM1 NFAM1 ENSGGOP00000050481 ENSGGOP00000050481 ENSGGOP00000050054 ENSGGOP00000050054 PRKD2 PRKD2 BTNL2 BTNL2 VAV3 VAV3 ENSGGOP00000048050 ENSGGOP00000048050 ENSGGOP00000047727 ENSGGOP00000047727 ENSGGOP00000047482 ENSGGOP00000047482 ENSGGOP00000045913 ENSGGOP00000045913 ENSGGOP00000045477 ENSGGOP00000045477 PTPRJ PTPRJ ENSGGOP00000044488 ENSGGOP00000044488 CFHR2 CFHR2 THEMIS THEMIS FCGR2B FCGR2B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSGGOP00000047763WNK lysine deficient protein kinase 1. (2786 aa)
NFATC2Nuclear factor of activated T cells 2. (925 aa)
C1SComplement C1s; Belongs to the peptidase S1 family. (780 aa)
FYNTyrosine-protein kinase. (537 aa)
EP300E1A binding protein p300. (2416 aa)
C6Complement C6. (934 aa)
NCKAP1LNCK associated protein 1 like. (1127 aa)
ZNFX1Zinc finger NFX1-type containing 1. (1918 aa)
C8BComplement C8 beta chain. (591 aa)
KHDRBS1KH RNA binding domain containing, signal transduction associated 1. (443 aa)
CFPComplement factor properdin. (469 aa)
RFTN1Raftlin, lipid raft linker 1. (578 aa)
RBCK1Uncharacterized protein. (204 aa)
FPR3N-formyl peptide receptor 3; Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. (353 aa)
TXKTyrosine-protein kinase. (527 aa)
FYB2FYN binding protein 2. (728 aa)
EIF2B1Eukaryotic translation initiation factor 2B subunit alpha; Belongs to the eIF-2B alpha/beta/delta subunits family. (306 aa)
THEMIS2Thymocyte selection associated family member 2. (643 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (599 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
G3R212_GORGORNA binding motif protein 14. (669 aa)
G3R3G6_GORGOComplement C1q A chain. (245 aa)
C1QCComplement C1q C chain. (245 aa)
C1QBComplement C1q B chain. (253 aa)
CMKLR1Chemerin chemokine-like receptor 1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
G3R3U7_GORGOMitochondrial antiviral signaling protein. (481 aa)
BAXBCL2 associated X, apoptosis regulator. (217 aa)
SYKTyrosine-protein kinase. (635 aa)
KLHL6Kelch like family member 6. (621 aa)
LAX1Lymphocyte transmembrane adaptor 1. (398 aa)
KLRD1Killer cell lectin like receptor D1. (179 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1040 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa)
MYO1GMyosin IG; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1018 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
EIF2B4Eukaryotic translation initiation factor 2B subunit delta; Belongs to the eIF-2B alpha/beta/delta subunits family. (523 aa)
ZBP1Z-DNA binding protein 1. (429 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (433 aa)
FCHO1FCH domain only 1. (927 aa)
CSKTyrosine-protein kinase. (450 aa)
PLPP4Uncharacterized protein. (118 aa)
PQBP1Polyglutamine-binding protein 1; Intrinsically disordered protein that acts as a scaffold, and which is involved in different processes, such as pre-mRNA splicing, transcription regulation, innate immunity and neuron development. Interacts with splicing-related factors via the intrinsically disordered region and regulates alternative splicing of target pre-mRNA species. May suppress the ability of POU3F2 to transactivate the DRD1 gene in a POU3F2 dependent manner. Can activate transcription directly or via association with the transcription machinery. May be involved in ATXN1 mutant-in [...] (265 aa)
XRCC5X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (732 aa)
C1RLComplement C1r subcomponent like; Belongs to the peptidase S1 family. (487 aa)
THY1Thy-1 cell surface antigen. (161 aa)
G3R8E2_GORGOIg-like domain-containing protein. (315 aa)
G3R8G6_GORGOHistocompatibility minor serpin domain containing; Belongs to the serpin family. (170 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
C4BPBComplement component 4 binding protein beta. (252 aa)
C4BPAComplement component 4 binding protein alpha. (599 aa)
BANK1B cell scaffold protein with ankyrin repeats 1. (785 aa)
VAV1Vav guanine nucleotide exchange factor 1. (788 aa)
PYHIN1Pyrin and HIN domain family member 1. (492 aa)
G3R9L0_GORGOPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family. (1072 aa)
G3R9N8_GORGOUncharacterized protein. (458 aa)
LYNTyrosine-protein kinase. (512 aa)
CD79BCD79b molecule. (230 aa)
SKAP1Src kinase associated phosphoprotein 1. (359 aa)
BTNL9Butyrophilin like 9. (536 aa)
BTN3A3Butyrophilin subfamily 3 member A3. (583 aa)
CFHR4Complement factor H related 4. (577 aa)
G3RCR2_GORGOMajor histocompatibility complex, class II, DP beta 1. (258 aa)
G3RD62_GORGOUncharacterized protein. (488 aa)
CD276CD276 molecule. (534 aa)
C8AComplement C8 alpha chain. (584 aa)
SHBSH2 domain containing adaptor protein B. (411 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
HEXIM1HEXIM P-TEFb complex subunit 1. (359 aa)
AIM2Absent in melanoma 2. (343 aa)
IFI16Interferon gamma inducible protein 16. (785 aa)
G3QTD2_GORGOProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (3503 aa)
MFAP4Microfibril associated protein 4. (278 aa)
CREBBPCREB binding protein. (2436 aa)
MNDAMyeloid cell nuclear differentiation antigen. (407 aa)
FFAR2Free fatty acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (330 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
G3QSI4_GORGORing finger and CCCH-type domains 1. (1093 aa)
FPR2N-formyl peptide receptor 2; Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophil chemotactic factors (By similarity). Binding of FMLP to the receptor causes activation of neutrophils (By similarity). This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system (By similarity). Receptor for the chemokine-like protein FAM19A5, mediating FAM19A5- stimulated macrophage chemotaxis and the inhibitory effect on TNFSF11/RANKL-induced osteoclast differentiation (By similarity). (350 aa)
FPR1fMet-Leu-Phe receptor; High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors. Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system (By similarity). Receptor for TAFA4, mediates its effects on chemoattracting macrophages, promoting phagocytosis and increasing ROS release (By similarity). (350 aa)
PLEKHA1Pleckstrin homology domain containing A1. (404 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (487 aa)
G3QQ53_GORGOUncharacterized protein. (263 aa)
SPG21SPG21 abhydrolase domain containing, maspardin. (308 aa)
G3QMP2_GORGOProtein tyrosine phosphatase non-receptor type 22. (693 aa)
TOMM70Translocase of outer mitochondrial membrane 70. (608 aa)
ITKTyrosine-protein kinase. (620 aa)
G3QLR1_GORGOUncharacterized protein. (488 aa)
KRT1Keratin 1; Belongs to the intermediate filament family. (644 aa)
G3QLP1_GORGOComplement C3d receptor 2. (1092 aa)
PSPC1Paraspeckle component 1. (523 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
PAK1Non-specific serine/threonine protein kinase. (554 aa)
NLRC4NLR family CARD domain containing 4. (1024 aa)
C1QBPComplement C1q binding protein. (281 aa)
GATA3GATA binding protein 3. (444 aa)
CFHR5Complement factor H related 5. (569 aa)
C5Complement C5. (1646 aa)
G3QIF7_GORGOComplement C7. (760 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (376 aa)
G3QGN8_GORGOTyrosine-protein kinase. (599 aa)
FYB1FYN binding protein 1. (839 aa)
MASP1Mannan binding lectin serine peptidase 1; Belongs to the peptidase S1 family. (728 aa)
CD38CD38 molecule. (300 aa)
NONOUncharacterized protein. (441 aa)
TREX1Three prime repair exonuclease 1. (369 aa)
PLD2Phospholipase. (933 aa)
LCP2Lymphocyte cytosolic protein 2. (533 aa)
CD3ECD3e molecule. (207 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (762 aa)
PDE4BPhosphodiesterase. (736 aa)
G3QF38_GORGOForkhead box P3. (441 aa)
COLEC10Collectin subfamily member 10. (277 aa)
G3QWJ4_GORGOUncharacterized protein. (895 aa)
ERMAPErythroblast membrane associated protein (Scianna blood group). (475 aa)
EIF2B5Eukaryotic translation initiation factor 2B subunit epsilon. (721 aa)
HHLA2HERV-H LTR-associating 2. (413 aa)
G3QXK1_GORGOZinc finger protein 683. (524 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa)
CTLA4Cytotoxic T-lymphocyte associated protein 4. (223 aa)
BTN2A1Butyrophilin subfamily 2 member A1. (531 aa)
C3AR1Complement C3a receptor 1; Belongs to the G-protein coupled receptor 1 family. (482 aa)
CACNB3Calcium voltage-gated channel auxiliary subunit beta 3. (487 aa)
CD79ACD79a molecule. (226 aa)
NFKBIDANK_REP_REGION domain-containing protein. (465 aa)
TYROBPTYRO protein tyrosine kinase binding protein. (113 aa)
SERPING1Serpin family G member 1; Belongs to the serpin family. (496 aa)
XRCC6X-ray repair cross complementing 6. (609 aa)
C9Complement C9. (559 aa)
BMXTyrosine-protein kinase. (675 aa)
RNF31Uncharacterized protein. (1072 aa)
STING1Transmembrane protein 173. (379 aa)
C5AR2Complement component 5a receptor 2. (337 aa)
CD19CD19 molecule. (556 aa)
CLUClusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. (449 aa)
G3RLC3_GORGOSH2 domain-containing protein. (568 aa)
RC3H2Ring finger and CCCH-type domains 2. (1191 aa)
PLA2G6Phospholipase A2 group VI. (806 aa)
PYCARDPYD and CARD domain containing. (195 aa)
TMEM269Transmembrane protein 269. (245 aa)
G3RPG3_GORGOMajor histocompatibility complex, class II, DQ beta 1. (261 aa)
BLKTyrosine-protein kinase. (446 aa)
FCER1GUncharacterized protein. (112 aa)
G3RPZ9_GORGOAnaphylatoxin-like domain-containing protein. (1528 aa)
SLA2Src like adaptor 2. (261 aa)
G3RQF4_GORGOLeukocyte immunoglobulin like receptor A2. (483 aa)
G3RQR5_GORGOIg-like domain-containing protein. (117 aa)
CD247CD247 molecule. (164 aa)
SRCTyrosine-protein kinase. (542 aa)
TECTyrosine-protein kinase. (631 aa)
CFHComplement factor H. (1227 aa)
G3RS61_GORGOCbl proto-oncogene B. (860 aa)
VTCN1V-set domain containing T cell activation inhibitor 1. (285 aa)
NR4A3Nuclear receptor subfamily 4 group A member 3. (550 aa)
MASP2Mannan binding lectin serine peptidase 2; Belongs to the peptidase S1 family. (686 aa)
G3RV54_GORGOProtein tyrosine phosphatase receptor type C. (1306 aa)
G3RVM4_GORGOUncharacterized protein. (158 aa)
LIMK1LIM domain kinase 1. (677 aa)
G3RVT8_GORGOIg-like domain-containing protein. (215 aa)
RGCCRegulator of cell cycle. (137 aa)
MALT1MALT1 paracaspase. (824 aa)
G3RXL1_GORGOIg-like domain-containing protein. (175 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (579 aa)
CD55Uncharacterized protein. (551 aa)
NFKBIZNFKB inhibitor zeta. (718 aa)
SFPQSplicing factor proline and glutamine rich. (590 aa)
PRAM1PML-RARA regulated adaptor molecule 1. (714 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
SUSD4Sushi domain containing 4. (490 aa)
TRIM5Tripartite motif-containing protein 5; Capsid-specific restriction factor that prevents infection from non-host-adapted retroviruses. Blocks viral replication early in the life cycle, after viral entry but before reverse transcription. In addition to acting as a capsid-specific restriction factor, also acts as a pattern recognition receptor that activates innate immune signaling in response to the retroviral capsid lattice. Binding to the viral capsid triggers its E3 ubiquitin ligase activity, and in concert with the heterodimeric ubiquitin conjugating enzyme complex UBE2V1- UBE2N (als [...] (493 aa)
G3S3W8_GORGOIg-like domain-containing protein. (175 aa)
G3S7D0_GORGOIg-like domain-containing protein. (200 aa)
G3S7P9_GORGOUncharacterized protein. (128 aa)
TBK1TANK binding kinase 1. (729 aa)
YES1Tyrosine-protein kinase. (558 aa)
CLEC6AC-type lectin domain containing 6A. (209 aa)
C3Complement C3. (1663 aa)
BTKTyrosine-protein kinase. (693 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (768 aa)
BTN1A1Butyrophilin subfamily 1 member A1. (526 aa)
CGASCyclic GMP-AMP synthase. (447 aa)
BLNKB cell linker. (456 aa)
VAV2Vav guanine nucleotide exchange factor 2. (878 aa)
CD3GCD3g molecule. (182 aa)
CFBComplement factor B Ba fragment; Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes (By similarity). (1112 aa)
G3SHX6_GORGOIGv domain-containing protein. (91 aa)
FCN2Ficolin 2. (313 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
G3SIR7_GORGOKu domain-containing protein. (334 aa)
HCKTyrosine-protein kinase. (526 aa)
C8GComplement C8 gamma chain; Belongs to the calycin superfamily. Lipocalin family. (202 aa)
CASP6Caspase 6; Belongs to the peptidase C14A family. (293 aa)
LAT2Linker for activation of T cells family member 2. (243 aa)
ENSGGOP00000029367Pyrin domain-containing protein. (110 aa)
ENSGGOP00000030108Ku domain-containing protein. (592 aa)
MS4A1Membrane spanning 4-domains A1. (297 aa)
ADAAdenosine deaminase. (412 aa)
CD28CD28 molecule. (220 aa)
ENSGGOP00000031261Myocyte enhancer factor 2C. (483 aa)
VSIG4V-set and immunoglobulin domain containing 4. (399 aa)
LCKTyrosine-protein kinase. (524 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
ENSGGOP00000032596CCHC NOA-type domain-containing protein. (417 aa)
ENSGGOP00000032772Uncharacterized protein. (104 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (840 aa)
ENSGGOP00000032880Zinc finger CCHC-type containing 3. (328 aa)
ENSGGOP00000033427Ig-like domain-containing protein. (195 aa)
ENSGGOP00000033674Ig-like domain-containing protein. (119 aa)
UBE2NUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)
CD3DCD3d molecule. (171 aa)
ENSGGOP00000035349Uncharacterized protein. (591 aa)
SIN3AUncharacterized protein. (154 aa)
ENSGGOP00000035952TNF receptor-associated factor. (485 aa)
SPPL3Signal peptide peptidase like 3. (384 aa)
COLEC11Collectin subfamily member 11. (285 aa)
ENSGGOP00000037423Uncharacterized protein. (309 aa)
ENSGGOP00000037735Uncharacterized protein. (471 aa)
ENSGGOP00000037798Uncharacterized protein. (246 aa)
C1RComplement C1r; Belongs to the peptidase S1 family. (719 aa)
C5AR1C5a anaphylatoxin chemotactic receptor 1; Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production. (351 aa)
PDE4DPhosphodiesterase. (748 aa)
ENSGGOP00000038632RRM domain-containing protein. (533 aa)
CRKLUncharacterized protein. (201 aa)
STOML2Stomatin like 2. (361 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
ENSGGOP00000039368RRM domain-containing protein. (153 aa)
MBL2Mannose-binding protein C; Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages (By similarity). (248 aa)
ENSGGOP00000039847annotation not available (241 aa)
ENSGGOP00000040139Uncharacterized protein. (86 aa)
BAG6BCL2 associated athanogene 6. (1190 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
TNFRSF21TNF receptor superfamily member 21. (655 aa)
ENSGGOP00000041462Uncharacterized protein. (164 aa)
MOGMyelin oligodendrocyte glycoprotein. (294 aa)
CACNB4Calcium voltage-gated channel auxiliary subunit beta 4. (520 aa)
ENSGGOP00000042007Complement factor D; Belongs to the peptidase S1 family. (279 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
FGRTyrosine-protein kinase. (529 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1066 aa)
EIF2B2Eukaryotic translation initiation factor 2B subunit beta; Belongs to the eIF-2B alpha/beta/delta subunits family. (351 aa)
EIF2B3Eukaryotic translation initiation factor 2B subunit gamma. (402 aa)
CD46CD46 molecule. (399 aa)
FCN3Ficolin 3. (299 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (916 aa)
ENSGGOP00000051997C-type lectin domain containing 7A. (247 aa)
ENSGGOP00000051962SAP domain-containing protein. (226 aa)
CD8ACD8a molecule. (236 aa)
BTN3A1Butyrophilin subfamily 3 member A1. (513 aa)
ENSGGOP00000051678Butyrophilin subfamily 2 member A2. (523 aa)
BCL10CARD domain-containing protein. (316 aa)
ENSGGOP00000050852annotation not available (362 aa)
NFAM1NFAT activating protein with ITAM motif 1. (270 aa)
ENSGGOP00000050481Uncharacterized protein. (441 aa)
ENSGGOP00000050054MORN repeat containing 5. (175 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa)
BTNL2Butyrophilin like 2. (482 aa)
VAV3Vav guanine nucleotide exchange factor 3. (875 aa)
ENSGGOP00000048050SH2 domain-containing protein. (132 aa)
ENSGGOP00000047727G protein-coupled receptor 32; Belongs to the G-protein coupled receptor 1 family. (356 aa)
ENSGGOP00000047482Ig-like domain-containing protein. (155 aa)
ENSGGOP00000045913DENN domain containing 1B. (775 aa)
ENSGGOP00000045477Non-specific serine/threonine protein kinase. (530 aa)
PTPRJProtein tyrosine phosphatase receptor type J. (1305 aa)
ENSGGOP00000044488Uncharacterized protein. (1750 aa)
CFHR2Sushi domain-containing protein. (146 aa)
THEMISThymocyte selection associated. (680 aa)
FCGR2BUncharacterized protein. (310 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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