STRINGSTRING
FCGR1A FCGR1A ENSGGOP00000051997 ENSGGOP00000051997 ENSGGOP00000050356 ENSGGOP00000050356 KMT5B KMT5B ENSGGOP00000047769 ENSGGOP00000047769 ENSGGOP00000047085 ENSGGOP00000047085 CADM1 CADM1 ENSGGOP00000045913 ENSGGOP00000045913 ENSGGOP00000043190 ENSGGOP00000043190 ENSGGOP00000042920 ENSGGOP00000042920 ENSGGOP00000042710 ENSGGOP00000042710 ZBTB1 ZBTB1 ENSGGOP00000038993 ENSGGOP00000038993 EXOSC3 EXOSC3 FZD5 FZD5 ENSGGOP00000035952 ENSGGOP00000035952 RASGRP1 RASGRP1 CD28 CD28 CD177 CD177 ENSGGOP00000028825 ENSGGOP00000028825 SH2D1A SH2D1A DHX36 DHX36 ARID5A ARID5A PLCG2 PLCG2 FAM49B FAM49B SCIMP SCIMP B2M B2M TGFB1 TGFB1 G3SDI2_GORGO G3SDI2_GORGO BTK BTK C3 C3 PAXIP1 PAXIP1 CD40 CD40 DDX58 DDX58 G3S7P9_GORGO G3S7P9_GORGO CD1A CD1A SHLD1 SHLD1 G3S3V1_GORGO G3S3V1_GORGO IL2 IL2 G3S124_GORGO G3S124_GORGO CD55 CD55 MAP3K7 MAP3K7 G3RXL1_GORGO G3RXL1_GORGO MALT1 MALT1 FADD FADD G3RVS4_GORGO G3RVS4_GORGO SLAMF1 SLAMF1 G3RVM4_GORGO G3RVM4_GORGO G3RV54_GORGO G3RV54_GORGO G3RUA1_GORGO G3RUA1_GORGO DDX50 DDX50 IL6 IL6 ARG1 ARG1 TNFSF4 TNFSF4 G3RRC5_GORGO G3RRC5_GORGO G3RR32_GORGO G3RR32_GORGO NOS2 NOS2 CRTAM CRTAM FBXO38 FBXO38 HMCES HMCES G3RKL3_GORGO G3RKL3_GORGO MLH1 MLH1 IL18 IL18 KIT KIT TYROBP TYROBP SASH3 SASH3 TREM2 TREM2 G3RG73_GORGO G3RG73_GORGO PTAFR PTAFR NSD2 NSD2 G3RE11_GORGO G3RE11_GORGO G3RD86_GORGO G3RD86_GORGO PRKCZ PRKCZ IL18R1 IL18R1 G3RAL4_GORGO G3RAL4_GORGO DDX1 DDX1 VAV1 VAV1 CD1D CD1D NOD2 NOD2 RSAD2 RSAD2 G3R570_GORGO G3R570_GORGO CD1E CD1E SLC22A13 SLC22A13 KLRD1 KLRD1 G3R3U7_GORGO G3R3U7_GORGO G3R317_GORGO G3R317_GORGO RAET1E RAET1E HSPD1 HSPD1 CLCF1 CLCF1 IL21 IL21 CD81 CD81 TFRC TFRC TRAF2 TRAF2 MSH2 MSH2 F2RL1 F2RL1 C5H17orf99 C5H17orf99 FCER2 FCER2 G3QVM2_GORGO G3QVM2_GORGO CLNK CLNK IL12A IL12A G3QUW7_GORGO G3QUW7_GORGO IL23R IL23R SPI1 SPI1 IL1B IL1B NECTIN2 NECTIN2 GATA3 GATA3 CD226 CD226 G3QT76_GORGO G3QT76_GORGO G3QT71_GORGO G3QT71_GORGO ATAD5 ATAD5 TRAF6 TRAF6 KMT5C KMT5C IL4 IL4 G3QRS4_GORGO G3QRS4_GORGO G3QRP1_GORGO G3QRP1_GORGO CD1B CD1B DDX21 DDX21 NLRP3 NLRP3 AP1G1 AP1G1 IL12B IL12B STX7 STX7 ITGAM ITGAM G3QN85_GORGO G3QN85_GORGO HPX HPX POMC POMC IL1R1 IL1R1 LAG3 LAG3 LAMP1 LAMP1 IL12RB1 IL12RB1 STX4 STX4 TP53BP1 TP53BP1 TBX21 TBX21 IL23A IL23A STAT6 STAT6 G3QF38_GORGO G3QF38_GORGO CD1C CD1C STAP1 STAP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FCGR1AUncharacterized protein. (374 aa)
ENSGGOP00000051997C-type lectin domain containing 7A. (247 aa)
ENSGGOP00000050356Replication timing regulatory factor 1. (2281 aa)
KMT5BLysine methyltransferase 5B. (885 aa)
ENSGGOP00000047769FAM35_C domain-containing protein. (778 aa)
ENSGGOP00000047085FAM35_C domain-containing protein. (752 aa)
CADM1Cell adhesion molecule 1. (450 aa)
ENSGGOP00000045913DENN domain containing 1B. (775 aa)
ENSGGOP00000043190Uncharacterized protein. (234 aa)
ENSGGOP00000042920Mitotic arrest deficient 2 like 2. (241 aa)
ENSGGOP00000042710Integrin beta. (813 aa)
ZBTB1Zinc finger and BTB domain containing 1. (686 aa)
ENSGGOP00000038993Helicase C-terminal domain-containing protein. (363 aa)
EXOSC3Exosome component 3. (275 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
ENSGGOP00000035952TNF receptor-associated factor. (485 aa)
RASGRP1RAS guanyl releasing protein 1. (848 aa)
CD28CD28 molecule. (220 aa)
CD177Uncharacterized protein. (144 aa)
ENSGGOP00000028825BRCT domain-containing protein. (83 aa)
SH2D1ASH2 domain-containing protein 1A; Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2. (128 aa)
DHX36DEAH-box helicase 36. (1008 aa)
ARID5AAT-rich interaction domain 5A. (594 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
FAM49BFamily with sequence similarity 49 member B. (324 aa)
SCIMPSLP adaptor and CSK interacting membrane protein. (144 aa)
B2MBeta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). (119 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
G3SDI2_GORGOMajor histocompatibility complex, class I-related; Belongs to the MHC class I family. (341 aa)
BTKTyrosine-protein kinase. (693 aa)
C3Complement C3. (1663 aa)
PAXIP1PAX interacting protein 1. (981 aa)
CD40CD40 molecule. (277 aa)
DDX58DExD/H-box helicase 58. (925 aa)
G3S7P9_GORGOUncharacterized protein. (128 aa)
CD1ACD1a molecule. (327 aa)
SHLD1Shieldin complex subunit 1. (205 aa)
G3S3V1_GORGOHelicase C-terminal domain-containing protein. (318 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (153 aa)
G3S124_GORGOKiller cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3. (405 aa)
CD55Uncharacterized protein. (551 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (579 aa)
G3RXL1_GORGOIg-like domain-containing protein. (175 aa)
MALT1MALT1 paracaspase. (824 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
G3RVS4_GORGOSignal transducer and activator of transcription. (787 aa)
SLAMF1Signaling lymphocytic activation molecule family member 1. (357 aa)
G3RVM4_GORGOUncharacterized protein. (158 aa)
G3RV54_GORGOProtein tyrosine phosphatase receptor type C. (1306 aa)
G3RUA1_GORGOIGc1 domain-containing protein; Belongs to the MHC class I family. (398 aa)
DDX50DExD-box helicase 50. (737 aa)
IL6Interleukin 6. (234 aa)
ARG1Arginase. (322 aa)
TNFSF4TNF superfamily member 4; Belongs to the tumor necrosis factor family. (183 aa)
G3RRC5_GORGOUncharacterized protein. (491 aa)
G3RR32_GORGOUncharacterized protein. (382 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1153 aa)
CRTAMCytotoxic and regulatory T cell molecule. (393 aa)
FBXO38F-box protein 38. (1188 aa)
HMCESAbasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...] (293 aa)
G3RKL3_GORGOMHC_I-like_Ag-recog domain-containing protein. (393 aa)
MLH1MutL homolog 1. (756 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (976 aa)
TYROBPTYRO protein tyrosine kinase binding protein. (113 aa)
SASH3SAM and SH3 domain containing 3. (380 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (230 aa)
G3RG73_GORGOCD177 molecule. (415 aa)
PTAFRPlatelet activating factor receptor; Belongs to the G-protein coupled receptor 1 family. (342 aa)
NSD2Nuclear receptor binding SET domain protein 2. (1365 aa)
G3RE11_GORGOSH2 domain containing 1B. (110 aa)
G3RD86_GORGOP2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
IL18R1Interleukin 18 receptor 1. (541 aa)
G3RAL4_GORGOMajor histocompatibility complex, class I, E; Belongs to the MHC class I family. (354 aa)
DDX1DEAD-box helicase 1. (740 aa)
VAV1Vav guanine nucleotide exchange factor 1. (788 aa)
CD1DCD1d molecule. (335 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1040 aa)
RSAD2Elp3 domain-containing protein. (361 aa)
G3R570_GORGOUncharacterized protein. (274 aa)
CD1ECD1e molecule. (388 aa)
SLC22A13Solute carrier family 22 member 13. (551 aa)
KLRD1Killer cell lectin like receptor D1. (179 aa)
G3R3U7_GORGOMitochondrial antiviral signaling protein. (481 aa)
G3R317_GORGOMajor histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (254 aa)
RAET1EMHC_I-like_Ag-recog domain-containing protein. (263 aa)
HSPD1Heat shock protein family D (Hsp60) member 1; Belongs to the chaperonin (HSP60) family. (609 aa)
CLCF1Uncharacterized protein. (322 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
CD81Tetraspanin. (260 aa)
TFRCTransferrin receptor. (760 aa)
TRAF2TNF receptor-associated factor. (451 aa)
MSH2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (934 aa)
F2RL1F2R like trypsin receptor 1. (397 aa)
C5H17orf99Chromosome 17 open reading frame 99. (265 aa)
FCER2Fc fragment of IgE receptor II. (321 aa)
G3QVM2_GORGOKiller cell lectin like receptor K1. (216 aa)
CLNKCytokine dependent hematopoietic cell linker. (428 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa)
G3QUW7_GORGOTIR domain-containing adapter molecule 1. (563 aa)
IL23RInterleukin 23 receptor. (629 aa)
SPI1Spi-1 proto-oncogene. (271 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa)
NECTIN2Nectin cell adhesion molecule 2. (539 aa)
GATA3GATA binding protein 3. (444 aa)
CD226CD226 molecule. (336 aa)
G3QT76_GORGOTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
G3QT71_GORGOLymphotoxin alpha; Belongs to the tumor necrosis factor family. (205 aa)
ATAD5ATPase family AAA domain containing 5. (1844 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
KMT5CLysine methyltransferase 5C. (465 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (153 aa)
G3QRS4_GORGOZP domain-containing protein. (290 aa)
G3QRP1_GORGOUncharacterized protein. (107 aa)
CD1BCD1b molecule. (333 aa)
DDX21DExD-box helicase 21. (783 aa)
NLRP3NLR family pyrin domain containing 3. (1028 aa)
AP1G1AP-1 complex subunit gamma. (825 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (328 aa)
STX7Syntaxin 7; Belongs to the syntaxin family. (261 aa)
ITGAMIntegrin subunit alpha M; Belongs to the integrin alpha chain family. (1152 aa)
G3QN85_GORGOSLAM family member 6. (331 aa)
HPXHemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. (462 aa)
POMCProopiomelanocortin. (267 aa)
IL1R1Interleukin 1 receptor type 1. (569 aa)
LAG3Lymphocyte activating 3. (525 aa)
LAMP1Lysosomal associated membrane protein 1. (465 aa)
IL12RB1Interleukin 12 receptor subunit beta 1. (662 aa)
STX4Syntaxin 4; Belongs to the syntaxin family. (297 aa)
TP53BP1Tumor protein p53 binding protein 1. (1972 aa)
TBX21T-box transcription factor 21. (535 aa)
IL23AInterleukin 23 subunit alpha. (189 aa)
STAT6Signal transducer and activator of transcription. (847 aa)
G3QF38_GORGOForkhead box P3. (441 aa)
CD1CCD1c molecule. (333 aa)
STAP1Signal transducing adaptor family member 1. (295 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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