STRINGSTRING
PIDD1 PIDD1 DAB2IP DAB2IP MOAP1 MOAP1 BEX3 BEX3 ENSGGOP00000033404 ENSGGOP00000033404 DEDD DEDD BAD BAD BLOC1S2 BLOC1S2 DAPK1 DAPK1 BCL2 BCL2 DIABLO DIABLO G3QSW1_GORGO G3QSW1_GORGO G3QT76_GORGO G3QT76_GORGO SPI1 SPI1 SORT1 SORT1 ITPRIPL2 ITPRIPL2 NF1 NF1 BAX BAX BID BID TNFRSF10B TNFRSF10B BAG3 BAG3 TRADD TRADD DELE1 DELE1 STK4 STK4 STK3 STK3 TNFRSF10A TNFRSF10A ENSGGOP00000046974 ENSGGOP00000046974 ENSGGOP00000047637 ENSGGOP00000047637 PIK3R1 PIK3R1 TNFRSF10C TNFRSF10C ENSGGOP00000051131 ENSGGOP00000051131 DEDD2 DEDD2 GABARAP GABARAP CASP8AP2 CASP8AP2 FADD FADD SKIL SKIL CRADD CRADD FASLG FASLG DAXX DAXX TNFRSF1A TNFRSF1A RAF1 RAF1 DDX3X DDX3X
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PIDD1P53-induced death domain protein 1. (910 aa)
DAB2IPDAB2 interacting protein. (1155 aa)
MOAP1Modulator of apoptosis 1. (351 aa)
BEX3Brain expressed X-linked 3. (121 aa)
ENSGGOP00000033404Caspase 8; Belongs to the peptidase C14A family. (496 aa)
DEDDDeath effector domain containing. (318 aa)
BADBCL2 associated agonist of cell death. (168 aa)
BLOC1S2Biogenesis of lysosomal organelles complex 1 subunit 2. (142 aa)
DAPK1Death associated protein kinase 1. (1397 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
DIABLOUncharacterized protein. (166 aa)
G3QSW1_GORGODEAD-box helicase 47; Belongs to the DEAD box helicase family. (455 aa)
G3QT76_GORGOTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
SPI1Spi-1 proto-oncogene. (271 aa)
SORT1Sortilin. (831 aa)
ITPRIPL2ITPRIP like 2. (535 aa)
NF1Neurofibromin 1. (2811 aa)
BAXBCL2 associated X, apoptosis regulator. (217 aa)
BIDBH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (195 aa)
TNFRSF10BTNF receptor superfamily member 10b. (440 aa)
BAG3BCL2 associated athanogene 3. (572 aa)
TRADDDeath domain-containing protein. (251 aa)
DELE1DAP3 binding cell death enhancer 1. (530 aa)
STK4Serine/threonine kinase 4. (487 aa)
STK3Serine/threonine kinase 3. (519 aa)
TNFRSF10ATNF receptor superfamily member 10a. (468 aa)
ENSGGOP00000046974Uncharacterized protein. (92 aa)
ENSGGOP00000047637Inositol 1,4,5-trisphosphate receptor interacting protein. (547 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (723 aa)
TNFRSF10CTNF receptor superfamily member 10c. (284 aa)
ENSGGOP00000051131Uncharacterized protein. (126 aa)
DEDD2Death effector domain containing 2. (330 aa)
GABARAPGABA type A receptor-associated protein. (117 aa)
CASP8AP2Caspase 8 associated protein 2. (1972 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
SKILSKI like proto-oncogene. (684 aa)
CRADDCASP2 and RIPK1 domain containing adaptor with death domain. (199 aa)
FASLGFas ligand; Belongs to the tumor necrosis factor family. (280 aa)
DAXXDeath domain associated protein. (743 aa)
TNFRSF1ATNF receptor superfamily member 1A. (455 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (630 aa)
DDX3XDEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. (733 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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