STRINGSTRING
RUFY4 RUFY4 DAPK1 DAPK1 LRSAM1 LRSAM1 ULK1 ULK1 FLCN FLCN BECN1 BECN1 TRIM13 TRIM13 RALB RALB G3QH20_GORGO G3QH20_GORGO PLEKHF1 PLEKHF1 G3QHP6_GORGO G3QHP6_GORGO TRIML1 TRIML1 UVRAG UVRAG SMCR8 SMCR8 TRIM8 TRIM8 SNX30 SNX30 GSK3A GSK3A IKBKG IKBKG SESN3 SESN3 ADRB2 ADRB2 IL4 IL4 G3QSD9_GORGO G3QSD9_GORGO IFNG IFNG G3QU07_GORGO G3QU07_GORGO TRIM21 TRIM21 G3QUW7_GORGO G3QUW7_GORGO PIP4K2B PIP4K2B NPRL2 NPRL2 GSK3B GSK3B TRIM38 TRIM38 FOXO1 FOXO1 LACRT LACRT PRKAA2 PRKAA2 TRIM14 TRIM14 TP53INP1 TP53INP1 ZC3H12A ZC3H12A ROCK1 ROCK1 PIK3CB PIK3CB SIRT1 SIRT1 TRIM68 TRIM68 TPCN1 TPCN1 G3R4R3_GORGO G3R4R3_GORGO NOD2 NOD2 RIPK2 RIPK2 VDAC1 VDAC1 STK11 STK11 PIM2 PIM2 BAG3 BAG3 PRKD1 PRKD1 SPTLC2 SPTLC2 G3R8T5_GORGO G3R8T5_GORGO PLK2 PLK2 KDR KDR RAB3GAP2 RAB3GAP2 HSPB8 HSPB8 SH3BP4 SH3BP4 MID2 MID2 UFL1 UFL1 ATF6 ATF6 G3RDD1_GORGO G3RDD1_GORGO ENDOG ENDOG SLC25A5 SLC25A5 SUPT5H SUPT5H SESN2 SESN2 BNIP3 BNIP3 PINK1 PINK1 G3RFQ9_GORGO G3RFQ9_GORGO SVIP SVIP MEFV MEFV TRIM27 TRIM27 RNF31 RNF31 STING1 STING1 HTT HTT ATG16L1 ATG16L1 KIAA1324 KIAA1324 FBXO7 FBXO7 HPSE HPSE TRIM22 TRIM22 TRIM32 TRIM32 PIK3C2A PIK3C2A IRGM IRGM TSC2 TSC2 PIP4K2C PIP4K2C PLK3 PLK3 G3RXC5_GORGO G3RXC5_GORGO MAP3K7 MAP3K7 PRKAA1 PRKAA1 LARP1 LARP1 MAPK3 MAPK3 AMBRA1 AMBRA1 TRIM5 TRIM5 NOD1 NOD1 KAT5 KAT5 TMEM59 TMEM59 TP53INP2 TP53INP2 TBK1 TBK1 RB1CC1 RB1CC1 SNX7 SNX7 RAB3GAP1 RAB3GAP1 SCOC SCOC GNAI3 GNAI3 CAMKK2 CAMKK2 HIF1A HIF1A TSC1 TSC1 CDK16 CDK16 PIP4K2A PIP4K2A ENSGGOP00000029762 ENSGGOP00000029762 DCN DCN SNX18 SNX18 ENSGGOP00000030563 ENSGGOP00000030563 PAFAH1B2 PAFAH1B2 WIPI1 WIPI1 MOAP1 MOAP1 ENSGGOP00000032596 ENSGGOP00000032596 ENSGGOP00000032712 ENSGGOP00000032712 ENSGGOP00000033982 ENSGGOP00000033982 TRIML2 TRIML2 MTDH MTDH ENSGGOP00000035401 ENSGGOP00000035401 OPTN OPTN GPSM1 GPSM1 FYCO1 FYCO1 ENSGGOP00000036167 ENSGGOP00000036167 ORMDL3 ORMDL3 EPM2A EPM2A LRRK2 LRRK2 CCNY CCNY PRKN PRKN XBP1 XBP1 SLC25A4 SLC25A4 SNX4 SNX4 ENSGGOP00000040048 ENSGGOP00000040048 SESN1 SESN1 ENSGGOP00000040095 ENSGGOP00000040095 ENSGGOP00000040125 ENSGGOP00000040125 BAD BAD ATG101 ATG101 ULK2 ULK2 WDR45 WDR45 HMOX1 HMOX1 BNIP3L BNIP3L ENSGGOP00000047330 ENSGGOP00000047330 BCL2L11 BCL2L11 ENSGGOP00000048104 ENSGGOP00000048104 NPRL3 NPRL3 ENSGGOP00000049592 ENSGGOP00000049592 WAC WAC ENSGGOP00000050852 ENSGGOP00000050852 ENSGGOP00000051208 ENSGGOP00000051208
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RUFY4RUN and FYVE domain containing 4. (607 aa)
DAPK1Death associated protein kinase 1. (1397 aa)
LRSAM1Leucine rich repeat and sterile alpha motif containing 1. (723 aa)
ULK1Unc-51 like autophagy activating kinase 1. (983 aa)
FLCNFolliculin. (579 aa)
BECN1Beclin 1. (450 aa)
TRIM13Tripartite motif containing 13. (410 aa)
RALBRAS like proto-oncogene B. (228 aa)
G3QH20_GORGOSerine palmitoyltransferase long chain base subunit 1. (441 aa)
PLEKHF1Pleckstrin homology and FYVE domain containing 1. (279 aa)
G3QHP6_GORGOVacuolar protein sorting 13 homolog D. (4225 aa)
TRIML1Tripartite motif family like 1. (468 aa)
UVRAGUV radiation resistance associated. (699 aa)
SMCR8SMCR8-C9orf72 complex subunit. (937 aa)
TRIM8Tripartite motif containing 8. (551 aa)
SNX30Sorting nexin family member 30. (437 aa)
GSK3AGlycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (483 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (487 aa)
SESN3Sestrin 3. (492 aa)
ADRB2Adrenoceptor beta 2. (413 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (153 aa)
G3QSD9_GORGOAutophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (550 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
G3QU07_GORGOC9orf72-SMCR8 complex subunit. (463 aa)
TRIM21Tripartite motif containing 21. (475 aa)
G3QUW7_GORGOTIR domain-containing adapter molecule 1. (563 aa)
PIP4K2BPhosphatidylinositol-5-phosphate 4-kinase type 2 beta. (416 aa)
NPRL2NPR2 like, GATOR1 complex subunit. (380 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (481 aa)
TRIM38Tripartite motif containing 38. (465 aa)
FOXO1Forkhead box O1. (655 aa)
LACRTLacritin. (137 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
TRIM14B box-type domain-containing protein. (110 aa)
TP53INP1Tumor protein p53 inducible nuclear protein 1. (241 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (599 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1041 aa)
SIRT1Sirtuin 1. (751 aa)
TRIM68Tripartite motif containing 68. (485 aa)
TPCN1Two pore segment channel 1. (888 aa)
G3R4R3_GORGOTripartite motif containing 65. (513 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1040 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa)
VDAC1Voltage dependent anion channel 1. (289 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (433 aa)
PIM2Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (311 aa)
BAG3BCL2 associated athanogene 3. (572 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (832 aa)
SPTLC2Serine palmitoyltransferase long chain base subunit 2. (566 aa)
G3R8T5_GORGOParkinsonism associated deglycase. (155 aa)
PLK2Serine/threonine-protein kinase PLK. (685 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
RAB3GAP2RAB3 GTPase activating non-catalytic protein subunit 2. (1401 aa)
HSPB8Heat shock protein family B (small) member 8; Belongs to the small heat shock protein (HSP20) family. (196 aa)
SH3BP4SH3 domain binding protein 4. (963 aa)
MID2Midline 2. (735 aa)
UFL1UFM1 specific ligase 1. (794 aa)
ATF6Activating transcription factor 6. (670 aa)
G3RDD1_GORGOWD repeat domain 24. (920 aa)
ENDOGEndonuclease. (297 aa)
SLC25A5Solute carrier family 25 member 5; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
SUPT5HTranscription elongation factor SPT5. (1140 aa)
SESN2Sestrin 2. (480 aa)
BNIP3Uncharacterized protein. (194 aa)
PINK1PTEN induced kinase 1. (581 aa)
G3RFQ9_GORGOUncharacterized protein. (841 aa)
SVIPSmall VCP interacting protein. (77 aa)
MEFVMEFV innate immuity regulator, pyrin. (781 aa)
TRIM27Tripartite motif containing 27. (513 aa)
RNF31Uncharacterized protein. (1072 aa)
STING1Transmembrane protein 173. (379 aa)
HTTHuntingtin. (3071 aa)
ATG16L1Autophagy related 16 like 1. (624 aa)
KIAA1324KIAA1324. (1013 aa)
FBXO7F-box protein 7. (522 aa)
HPSEHeparanase. (543 aa)
TRIM22Tripartite motif containing 22. (498 aa)
TRIM32Tripartite motif containing 32. (653 aa)
PIK3C2APhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1686 aa)
IRGMImmunity related GTPase M. (181 aa)
TSC2TSC complex subunit 2. (1806 aa)
PIP4K2CPhosphatidylinositol-5-phosphate 4-kinase type 2 gamma. (421 aa)
PLK3Serine/threonine-protein kinase PLK. (673 aa)
G3RXC5_GORGOTranscription factor EB. (551 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (579 aa)
PRKAA1Non-specific serine/threonine protein kinase. (574 aa)
LARP1La ribonucleoprotein domain family member 1. (1019 aa)
MAPK3Mitogen-activated protein kinase. (322 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1298 aa)
TRIM5Tripartite motif-containing protein 5; Capsid-specific restriction factor that prevents infection from non-host-adapted retroviruses. Blocks viral replication early in the life cycle, after viral entry but before reverse transcription. In addition to acting as a capsid-specific restriction factor, also acts as a pattern recognition receptor that activates innate immune signaling in response to the retroviral capsid lattice. Binding to the viral capsid triggers its E3 ubiquitin ligase activity, and in concert with the heterodimeric ubiquitin conjugating enzyme complex UBE2V1- UBE2N (als [...] (493 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (953 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa)
TMEM59Transmembrane protein 59. (324 aa)
TP53INP2Tumor protein p53 inducible nuclear protein 2. (220 aa)
TBK1TANK binding kinase 1. (729 aa)
RB1CC1RB1 inducible coiled-coil 1. (1594 aa)
SNX7Sorting nexin 7. (397 aa)
RAB3GAP1RAB3 GTPase activating protein catalytic subunit 1. (988 aa)
SCOCShort coiled-coil protein. (159 aa)
GNAI3G protein subunit alpha i3. (354 aa)
CAMKK2Calcium/calmodulin dependent protein kinase kinase 2. (588 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (850 aa)
TSC1TSC complex subunit 1. (1164 aa)
CDK16Cyclin dependent kinase 16. (570 aa)
PIP4K2APhosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (396 aa)
ENSGGOP00000029762DJ-1_PfpI domain-containing protein. (168 aa)
DCNDecorin; May affect the rate of fibrils formation. (359 aa)
SNX18PX domain-containing protein. (430 aa)
ENSGGOP00000030563Autophagy related 2A. (1938 aa)
PAFAH1B2Platelet activating factor acetylhydrolase 1b catalytic subunit 2. (229 aa)
WIPI1WD repeat domain, phosphoinositide interacting 1. (447 aa)
MOAP1Modulator of apoptosis 1. (351 aa)
ENSGGOP00000032596CCHC NOA-type domain-containing protein. (417 aa)
ENSGGOP00000032712Uncharacterized protein. (264 aa)
ENSGGOP00000033982Uncharacterized protein. (256 aa)
TRIML2Tripartite motif family like 2. (436 aa)
MTDHMetadherin. (612 aa)
ENSGGOP00000035401PX domain-containing protein. (443 aa)
OPTNOptineurin. (577 aa)
GPSM1G protein signaling modulator 1. (707 aa)
FYCO1FYVE and coiled-coil domain containing 1. (1498 aa)
ENSGGOP00000036167SH3 domain containing GRB2 like, endophilin B1. (402 aa)
ORMDL3ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)
EPM2AEPM2A glucan phosphatase, laforin. (275 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
CCNYCyclin Y; Belongs to the cyclin family. (341 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa)
XBP1BZIP domain-containing protein. (380 aa)
SLC25A4Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
SNX4Sorting nexin 4. (450 aa)
ENSGGOP00000040048Dehydrogenase/reductase X-linked; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (293 aa)
SESN1Sestrin 1. (551 aa)
ENSGGOP00000040095Uncharacterized protein. (298 aa)
ENSGGOP00000040125Uncharacterized protein. (217 aa)
BADBCL2 associated agonist of cell death. (168 aa)
ATG101Autophagy related 101. (218 aa)
ULK2Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. (1036 aa)
WDR45WD repeat domain 45. (361 aa)
HMOX1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (289 aa)
BNIP3LBCL2 interacting protein 3 like. (199 aa)
ENSGGOP00000047330Uncharacterized protein. (261 aa)
BCL2L11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (198 aa)
ENSGGOP00000048104annotation not available (264 aa)
NPRL3NPR3 like, GATOR1 complex subunit. (569 aa)
ENSGGOP00000049592Calcium binding and coiled-coil domain 2. (501 aa)
WACWW domain containing adaptor with coiled-coil. (666 aa)
ENSGGOP00000050852annotation not available (362 aa)
ENSGGOP00000051208DUF3384 domain-containing protein. (525 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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