STRINGSTRING
ADORA2B ADORA2B CXCL17 CXCL17 RORA RORA ENSGGOP00000033459 ENSGGOP00000033459 ENSGGOP00000033934 ENSGGOP00000033934 C5AR1 C5AR1 SULF1 SULF1 ENSGGOP00000048540 ENSGGOP00000048540 ENSGGOP00000032087 ENSGGOP00000032087 HIF1A HIF1A TGFB1 TGFB1 ARNT ARNT C3 C3 BRCA1 BRCA1 IL6 IL6 PTGS2 PTGS2 HPSE HPSE CCBE1 CCBE1 C3AR1 C3AR1 EIF2AK3 EIF2AK3 G3R5D7_GORGO G3R5D7_GORGO ATF4 ATF4 ISL1 ISL1 NOX1 NOX1 G3QVG0_GORGO G3QVG0_GORGO FLT4 FLT4 IL1B IL1B IL1A IL1A NODAL NODAL C5 C5 SULF2 SULF2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADORA2BAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (332 aa)
CXCL17C-X-C motif chemokine ligand 17. (119 aa)
RORARAR related orphan receptor A. (555 aa)
ENSGGOP00000033459BZIP domain-containing protein. (350 aa)
ENSGGOP00000033934Uncharacterized protein. (318 aa)
C5AR1C5a anaphylatoxin chemotactic receptor 1; Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production. (351 aa)
SULF1Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (883 aa)
ENSGGOP00000048540Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa)
ENSGGOP00000032087BZIP domain-containing protein. (342 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (850 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
ARNTAryl hydrocarbon receptor nuclear translocator. (789 aa)
C3Complement C3. (1663 aa)
BRCA1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1824 aa)
IL6Interleukin 6. (234 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
HPSEHeparanase. (543 aa)
CCBE1Collagen and calcium binding EGF domains 1. (406 aa)
C3AR1Complement C3a receptor 1; Belongs to the G-protein coupled receptor 1 family. (482 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1116 aa)
G3R5D7_GORGOUncharacterized protein. (366 aa)
ATF4Activating transcription factor 4. (351 aa)
ISL1ISL LIM homeobox 1. (351 aa)
NOX1NADPH oxidase 1. (564 aa)
G3QVG0_GORGOBasigin (Ok blood group). (386 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1319 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (271 aa)
NODALNodal growth differentiation factor. (347 aa)
C5Complement C5. (1646 aa)
SULF2Sulfatase 2. (851 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
Server load: low (12%) [HD]