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KDR | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa) | ||||
RHOA | Uncharacterized protein. (179 aa) | ||||
SMOC2 | SPARC related modular calcium binding 2. (457 aa) | ||||
FGFR1 | Fibroblast growth factor receptor. (820 aa) | ||||
ADAM17 | ADAM metallopeptidase domain 17. (824 aa) | ||||
BMPER | BMP binding endothelial regulator. (685 aa) | ||||
EDN1 | Endothelin 1. (212 aa) | ||||
G3RC81_GORGO | F-box and WD repeat domain containing 9. (478 aa) | ||||
CXCL13 | C-X-C motif chemokine. (109 aa) | ||||
G3RF44_GORGO | Forkhead box C2. (442 aa) | ||||
BMP4 | Bone morphogenetic protein 4. (408 aa) | ||||
PROX1 | Prospero homeobox 1. (737 aa) | ||||
PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (220 aa) | ||||
PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa) | ||||
GRN | Granulin precursor. (593 aa) | ||||
PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa) | ||||
TEK | TEK receptor tyrosine kinase. (1124 aa) | ||||
CALR | Calreticulin. (417 aa) | ||||
FGFBP1 | Fibroblast growth factor binding protein 1. (234 aa) | ||||
SPARC | Secreted protein acidic and cysteine rich. (303 aa) | ||||
CCBE1 | Collagen and calcium binding EGF domains 1. (406 aa) | ||||
HDAC7 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1008 aa) | ||||
PRCP | Prolylcarboxypeptidase. (517 aa) | ||||
RIN2 | Ras and Rab interactor 2. (939 aa) | ||||
NOS3 | Nitric oxide synthase 3. (997 aa) | ||||
ANGPT4 | Angiopoietin 4. (503 aa) | ||||
VASH1 | Vasohibin 1. (365 aa) | ||||
G3RLN8_GORGO | Signal transducer and activator of transcription. (652 aa) | ||||
PATZ1 | POZ/BTB and AT hook containing zinc finger 1. (687 aa) | ||||
FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) | ||||
PTGS2 | Prostaglandin-endoperoxide synthase 2. (604 aa) | ||||
PIK3C2A | Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1686 aa) | ||||
G3RSQ1_GORGO | Legumain. (433 aa) | ||||
HDAC5 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1122 aa) | ||||
RGCC | Regulator of cell cycle. (137 aa) | ||||
HRG | Histidine rich glycoprotein. (540 aa) | ||||
G3RXP9_GORGO | Nuclear receptor subfamily 2 group F member 2. (414 aa) | ||||
G3RXW1_GORGO | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (372 aa) | ||||
ZNF580 | Zinc finger protein 580. (172 aa) | ||||
PTK2 | Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa) | ||||
AGT | Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. (485 aa) | ||||
G3R1H9_GORGO | Apolipoprotein H. (286 aa) | ||||
MMRN2 | Multimerin 2. (838 aa) | ||||
PDCD10 | Programmed cell death 10. (212 aa) | ||||
EPHA2 | EPH receptor A2. (876 aa) | ||||
RHOJ | Ras homolog family member J. (214 aa) | ||||
PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa) | ||||
SP100 | Nuclear autoantigen Sp-100; Together with PML, this tumor suppressor is a major constituent of the PML bodies, a subnuclear organelle involved in a large number of physiological processes including cell growth, differentiation and apoptosis. Functions as a transcriptional coactivator of ETS1 and ETS2. Under certain conditions, it may also act as a corepressor of ETS1 preventing its binding to DNA. Through the regulation of ETS1 it may play a role in angiogenesis, controlling endothelial cell motility and invasion. Through interaction with the MRN complex it may be involved in the regul [...] (209 aa) | ||||
ITGB3 | Integrin beta; Belongs to the integrin beta chain family. (837 aa) | ||||
JUP | Junction plakoglobin. (745 aa) | ||||
AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) | ||||
WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) | ||||
G3QWN1_GORGO | Synaptojanin 2 binding protein. (145 aa) | ||||
SEMA5A | Semaphorin 5A. (1041 aa) | ||||
FGF18 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) | ||||
G3QW59_GORGO | Gln-synt_C domain-containing protein. (325 aa) | ||||
NF1 | Neurofibromin 1. (2811 aa) | ||||
AAMP | Angio associated migratory cell protein. (434 aa) | ||||
G3QVG0_GORGO | Basigin (Ok blood group). (386 aa) | ||||
FLT4 | Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1319 aa) | ||||
ACVRL1 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa) | ||||
MEOX2 | Mesenchyme homeobox 2. (303 aa) | ||||
GATA3 | GATA binding protein 3. (444 aa) | ||||
GATA2 | GATA binding protein 2. (480 aa) | ||||
G3QT76_GORGO | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) | ||||
GDF2 | Growth differentiation factor 2. (429 aa) | ||||
EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1183 aa) | ||||
ROCK2 | Uncharacterized protein; Belongs to the protein kinase superfamily. (460 aa) | ||||
FGF4 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa) | ||||
G3R755_GORGO | DnaJ heat shock protein family (Hsp40) member A4. (390 aa) | ||||
ATP5F1B | ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (529 aa) | ||||
SASH1 | SAM and SH3 domain containing 1. (1190 aa) | ||||
NR2E1 | Nuclear receptor subfamily 2 group E member 1. (422 aa) | ||||
ANGPT2 | Angiopoietin 2. (496 aa) | ||||
SRPX2 | Sushi repeat containing protein X-linked 2. (465 aa) | ||||
SIRT1 | Sirtuin 1. (751 aa) | ||||
NOTCH1 | Uncharacterized protein. (1606 aa) | ||||
ALOX12 | Arachidonate 12-lipoxygenase, 12S type. (663 aa) | ||||
PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1041 aa) | ||||
NRP2 | Neuropilin; Belongs to the neuropilin family. (926 aa) | ||||
ANXA3 | Annexin. (325 aa) | ||||
G3R4E1_GORGO | Forkhead box P1. (693 aa) | ||||
ATP2B4 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1225 aa) | ||||
ABL1 | Tyrosine-protein kinase. (1149 aa) | ||||
GADD45A | Growth arrest and DNA damage inducible alpha. (165 aa) | ||||
AMOT | Angiomotin. (1086 aa) | ||||
G3R1K1_GORGO | Ephrin A1; Belongs to the ephrin family. (205 aa) | ||||
BCAR1 | BCAR1 scaffold protein, Cas family member. (916 aa) | ||||
ATP2B4-2 | Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (554 aa) | ||||
AGTR2 | Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. (363 aa) | ||||
EMP2 | Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (167 aa) | ||||
VEGFC | PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (230 aa) | ||||
BCAS3 | BCAS3 microtubule associated cell migration factor. (950 aa) | ||||
THBS1 | Thrombospondin 1. (1173 aa) | ||||
PRKD2 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa) | ||||
ENSGGOP00000049938 | Uncharacterized protein. (177 aa) | ||||
JCAD | Junctional cadherin 5 associated. (1359 aa) | ||||
ENSGGOP00000046735 | Non-specific serine/threonine protein kinase. (524 aa) | ||||
SCARB1 | Scavenger receptor class B member 1; Belongs to the CD36 family. (509 aa) | ||||
HMOX1 | Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (289 aa) | ||||
ENSGGOP00000045937 | Protein tyrosine phosphatase receptor type M. (1379 aa) | ||||
ENSGGOP00000045621 | Uncharacterized protein. (252 aa) | ||||
ENSGGOP00000045523 | Uncharacterized protein. (281 aa) | ||||
STARD13 | StAR related lipid transfer domain containing 13. (1113 aa) | ||||
PTN | Pleiotrophin. (172 aa) | ||||
MECP2 | Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa) | ||||
ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif 9. (1896 aa) | ||||
ENSGGOP00000043921 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (395 aa) | ||||
PATZ1-2 | C2H2-type domain-containing protein. (145 aa) | ||||
ENSGGOP00000042865 | EGF-like domain-containing protein. (158 aa) | ||||
SP100-2 | SP100 nuclear antigen. (885 aa) | ||||
ENSGGOP00000042328 | CFC domain-containing protein. (163 aa) | ||||
CIB1 | Calcium and integrin binding 1. (235 aa) | ||||
ENSGGOP00000042002 | Uncharacterized protein. (476 aa) | ||||
MET | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1409 aa) | ||||
RRAS | RAS related. (218 aa) | ||||
ENSGGOP00000041051 | Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family. (1242 aa) | ||||
ENSGGOP00000040217 | Uncharacterized protein. (371 aa) | ||||
ATP5F1A | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (576 aa) | ||||
ITGB1BP1 | Integrin subunit beta 1 binding protein 1. (200 aa) | ||||
BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1042 aa) | ||||
ENSGGOP00000039174 | Uncharacterized protein. (417 aa) | ||||
RAC1 | Rac family small GTPase 1. (211 aa) | ||||
SPRED1 | Sprouty related EVH1 domain containing 1. (444 aa) | ||||
BMP10 | Bone morphogenetic protein 10. (424 aa) | ||||
NFE2L2 | Nuclear factor, erythroid 2 like 2. (600 aa) | ||||
GPI | Glucose-6-phosphate isomerase; Belongs to the GPI family. (573 aa) | ||||
FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (258 aa) | ||||
GPLD1 | Glycosylphosphatidylinositol specific phospholipase D1. (840 aa) | ||||
ENSGGOP00000032639 | Uncharacterized protein. (387 aa) | ||||
PPARG | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa) | ||||
DAB2IP | DAB2 interacting protein. (1155 aa) | ||||
ENSGGOP00000031261 | Myocyte enhancer factor 2C. (483 aa) | ||||
SLIT2 | Slit guidance ligand 2. (1542 aa) | ||||
RHOB | Ras homolog family member B. (196 aa) | ||||
DCN | Decorin; May affect the rate of fibrils formation. (359 aa) | ||||
ENSGGOP00000029090 | Uncharacterized protein. (195 aa) | ||||
DLL4 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa) | ||||
GLUL | Glutamine synthetase. (373 aa) | ||||
KLF4 | Kruppel like factor 4. (479 aa) | ||||
HIF1A | Hypoxia inducible factor 1 subunit alpha. (850 aa) | ||||
G3SIL0_GORGO | Adhesion G protein-coupled receptor B1; Belongs to the G-protein coupled receptor 2 family. (1570 aa) | ||||
G3SIC3_GORGO | Uncharacterized protein. (337 aa) | ||||
G3SGV8_GORGO | Gln-synt_C domain-containing protein. (299 aa) | ||||
STC1 | Stanniocalcin 1. (247 aa) | ||||
HMGB1 | Uncharacterized protein. (215 aa) | ||||
NUS1 | NUS1 dehydrodolichyl diphosphate synthase subunit. (293 aa) | ||||
FBXW7 | F-box and WD repeat domain containing 7. (707 aa) | ||||
TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) | ||||
PDPK1 | Protein kinase domain-containing protein. (347 aa) | ||||
ENSGGOP00000024523 | annotation not available (408 aa) | ||||
HDAC9 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1066 aa) | ||||
MAP3K3 | Mitogen-activated protein kinase kinase kinase 3. (657 aa) | ||||
CD40 | CD40 molecule. (277 aa) | ||||
PIK3CG | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa) | ||||
G3S6W7_GORGO | Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (44 aa) | ||||
TBXA2R | Thromboxane A2 receptor; Belongs to the G-protein coupled receptor 1 family. (343 aa) | ||||
ANGPT1 | Angiopoietin 1. (498 aa) | ||||
G3S2A2_GORGO | Caspase recruitment domain family member 10. (1028 aa) | ||||
CEACAM1 | Carcinoembryonic antigen related cell adhesion molecule 1. (525 aa) | ||||
MAP2K5 | Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (448 aa) | ||||
ANXA1 | Annexin. (346 aa) | ||||
TDGF1 | Growth factor; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. (188 aa) | ||||
ETS1 | ETS proto-oncogene 1, transcription factor. (485 aa) | ||||
HSPB1 | Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (205 aa) | ||||
TSTA3 | Tissue specific transplantation antigen P35B. (344 aa) | ||||
FGF16 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) | ||||
KRIT1 | Uncharacterized protein. (736 aa) | ||||
NRP1 | Neuropilin; Belongs to the neuropilin family. (923 aa) | ||||
FUT1 | Galactoside 2-alpha-L-fucosyltransferase 1; Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Gal-beta-) called the H antigen which is an essential substrate for the final step in the soluble A and B antigen synthesis pathway. Belongs to the glycosyltransferase 11 family. (366 aa) | ||||
G3QEV1_GORGO | Semaphorin 4A; Belongs to the semaphorin family. (761 aa) | ||||
MAP2K3 | Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa) | ||||
PLPP3 | acidPPc domain-containing protein. (311 aa) | ||||
SERPINF1 | Serpin family F member 1; Belongs to the serpin family. (418 aa) | ||||
ZC3H12A | Zinc finger CCCH-type containing 12A. (599 aa) | ||||
PRKD1 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (832 aa) | ||||
G3R9L0_GORGO | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family. (1072 aa) | ||||
G3RA25_GORGO | Sp1 transcription factor. (786 aa) | ||||
WNT7A | Protein Wnt-7a; Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta- catenin signaling pathway (By similarity). Plays an important role in embryonic development, including dorsal versus ventral patterning during limb development, skeleton development and urogenital tract development. Required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation (By similarity). Required for normal, sexually dimorphic development of the Mullerian ducts, and for normal fertility in both sexes. Required for normal [...] (345 aa) | ||||
G3RAC9_GORGO | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (395 aa) | ||||
PLK2 | Serine/threonine-protein kinase PLK. (685 aa) |