STRINGSTRING
EPB41L5 EPB41L5 AGT AGT SERPINF1 SERPINF1 HBEGF HBEGF PLPP3 PLPP3 PPM1F PPM1F MAP2K3 MAP2K3 G3QEV1_GORGO G3QEV1_GORGO PTEN PTEN IQSEC1 IQSEC1 FUT1 FUT1 ITGA2 ITGA2 NRP1 NRP1 TACR1 TACR1 DUSP10 DUSP10 MCC MCC KRIT1 KRIT1 FGF16 FGF16 TSTA3 TSTA3 HSPB1 HSPB1 ETS1 ETS1 PTPN23 PTPN23 TDGF1 TDGF1 EPB41L4B EPB41L4B DOCK5 DOCK5 RREB1 RREB1 G3QPK5_GORGO G3QPK5_GORGO FGF10 FGF10 ANXA1 ANXA1 MAP2K5 MAP2K5 ROCK2 ROCK2 ADIPOR1 ADIPOR1 FGF7 FGF7 IL4 IL4 EGF EGF EVL EVL GDF2 GDF2 G3QT76_GORGO G3QT76_GORGO IFNG IFNG ADAM9 ADAM9 GATA2 GATA2 GATA3 GATA3 MEOX2 MEOX2 ACVRL1 ACVRL1 FLT4 FLT4 RAB25 RAB25 PTPRG PTPRG G3QVG0_GORGO G3QVG0_GORGO AAMP AAMP NF1 NF1 G3QVZ5_GORGO G3QVZ5_GORGO G3QW59_GORGO G3QW59_GORGO FGF18 FGF18 G3QWN1_GORGO G3QWN1_GORGO WNT5A WNT5A AKT3 AKT3 ITGB3 ITGB3 SP100 SP100 PLCG1 PLCG1 RHOJ RHOJ EPHA2 EPHA2 PDCD10 PDCD10 MARVELD3 MARVELD3 MMRN2 MMRN2 G3R1H9_GORGO G3R1H9_GORGO ZC3H12A ZC3H12A G3R1K1_GORGO G3R1K1_GORGO NRP2 NRP2 PIK3CB PIK3CB ALOX12 ALOX12 NOTCH1 NOTCH1 SRPX2 SRPX2 ANGPT2 ANGPT2 NR2E1 NR2E1 SASH1 SASH1 FGF4 FGF4 JUP JUP SIRT1 SIRT1 ANXA3 ANXA3 G3R4E1_GORGO G3R4E1_GORGO ATP2B4 ATP2B4 ABL1 ABL1 MTOR MTOR GADD45A GADD45A G3R5K0_GORGO G3R5K0_GORGO AMOT AMOT SEMA5A SEMA5A G3R755_GORGO G3R755_GORGO ATP5F1B ATP5F1B PRKD1 PRKD1 PRKCE PRKCE TACSTD2 TACSTD2 CTSH CTSH G3R9L0_GORGO G3R9L0_GORGO G3RA25_GORGO G3RA25_GORGO WNT7A WNT7A ARSJ ARSJ G3RAC9_GORGO G3RAC9_GORGO PLK2 PLK2 KDR KDR RHOA RHOA SMOC2 SMOC2 GAB4 GAB4 FGFR1 FGFR1 ADAM17 ADAM17 BMPER BMPER EDN1 EDN1 G3RC81_GORGO G3RC81_GORGO ITGA3 ITGA3 MMP9 MMP9 CXCL13 CXCL13 PTPRR PTPRR RAB11A RAB11A VIL1 VIL1 G3RF44_GORGO G3RF44_GORGO BMP4 BMP4 DOCK1 DOCK1 PROX1 PROX1 IRS2 IRS2 PDGFB PDGFB PTK2B PTK2B GRN GRN PRKCA PRKCA TEK TEK CALR CALR FGFBP1 FGFBP1 SPARC SPARC CCBE1 CCBE1 HDAC7 HDAC7 PRCP PRCP RIN2 RIN2 NOS3 NOS3 ANGPT4 ANGPT4 TGFBR2 TGFBR2 VASH1 VASH1 G3RLN8_GORGO G3RLN8_GORGO CORO1C CORO1C PATZ1 PATZ1 SOX9 SOX9 G3RNB7_GORGO G3RNB7_GORGO FGF1 FGF1 PTGS2 PTGS2 CAPN7 CAPN7 SRC SRC RTN4 RTN4 PIK3C2A PIK3C2A G3RSQ1_GORGO G3RSQ1_GORGO HDAC5 HDAC5 RGCC RGCC HRG HRG G3RXP9_GORGO G3RXP9_GORGO G3RXW1_GORGO G3RXW1_GORGO ZNF580 ZNF580 PTK2 PTK2 CEACAM1 CEACAM1 G3S2A2_GORGO G3S2A2_GORGO ANGPT1 ANGPT1 MAPRE2 MAPRE2 PFN2 PFN2 TBXA2R TBXA2R G3S6W7_GORGO G3S6W7_GORGO PIK3CG PIK3CG CD40 CD40 MAP3K3 MAP3K3 HDAC9 HDAC9 ENSGGOP00000024523 ENSGGOP00000024523 PDPK1 PDPK1 ARSI ARSI TGFB1 TGFB1 FBXW7 FBXW7 NUS1 NUS1 HMGB1 HMGB1 STC1 STC1 G3SGV8_GORGO G3SGV8_GORGO G3SIC3_GORGO G3SIC3_GORGO PLCG2 PLCG2 G3SIL0_GORGO G3SIL0_GORGO HIF1A HIF1A KLF4 KLF4 GLUL GLUL DLL4 DLL4 ENSGGOP00000029090 ENSGGOP00000029090 DCN DCN RHOB RHOB SLIT2 SLIT2 MACF1 MACF1 ENSGGOP00000031261 ENSGGOP00000031261 ENSGGOP00000031306 ENSGGOP00000031306 DAB2IP DAB2IP PPARG PPARG ENSGGOP00000032639 ENSGGOP00000032639 GPLD1 GPLD1 FGF2 FGF2 GPI GPI GLIPR2 GLIPR2 NFE2L2 NFE2L2 BMP10 BMP10 SPRED1 SPRED1 RAC1 RAC1 ENSGGOP00000034961 ENSGGOP00000034961 ENSGGOP00000036783 ENSGGOP00000036783 ARSB ARSB ENSGGOP00000039174 ENSGGOP00000039174 BMPR2 BMPR2 ITGB1BP1 ITGB1BP1 ATP5F1A ATP5F1A ENSGGOP00000040217 ENSGGOP00000040217 ENSGGOP00000040417 ENSGGOP00000040417 ENSGGOP00000041051 ENSGGOP00000041051 C5H5orf30 C5H5orf30 ENSGGOP00000041427 ENSGGOP00000041427 RRAS RRAS MET MET ARF6 ARF6 ENSGGOP00000042002 ENSGGOP00000042002 CCR6 CCR6 CIB1 CIB1 ENSGGOP00000042328 ENSGGOP00000042328 HAS2 HAS2 SP100-2 SP100-2 ENSGGOP00000042865 ENSGGOP00000042865 ENSGGOP00000043386 ENSGGOP00000043386 PATZ1-2 PATZ1-2 ENSGGOP00000043921 ENSGGOP00000043921 ADAMTS9 ADAMTS9 MECP2 MECP2 PTN PTN STARD13 STARD13 ENSGGOP00000045523 ENSGGOP00000045523 ENSGGOP00000045621 ENSGGOP00000045621 ENSGGOP00000045937 ENSGGOP00000045937 HMOX1 HMOX1 SCARB1 SCARB1 ENSGGOP00000046735 ENSGGOP00000046735 JCAD JCAD ENSGGOP00000048202 ENSGGOP00000048202 HDAC6 HDAC6 ENSGGOP00000049938 ENSGGOP00000049938 PRKD2 PRKD2 THBS1 THBS1 BCAS3 BCAS3 VEGFC VEGFC EMP2 EMP2 AGTR2 AGTR2 ATP2B4-2 ATP2B4-2 BCAR1 BCAR1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EPB41L5Erythrocyte membrane protein band 4.1 like 5. (733 aa)
AGTAngiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. (485 aa)
SERPINF1Serpin family F member 1; Belongs to the serpin family. (418 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
PLPP3acidPPc domain-containing protein. (311 aa)
PPM1FProtein phosphatase, Mg2+/Mn2+ dependent 1F. (454 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa)
G3QEV1_GORGOSemaphorin 4A; Belongs to the semaphorin family. (761 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
IQSEC1IQ motif and Sec7 domain 1. (1101 aa)
FUT1Galactoside 2-alpha-L-fucosyltransferase 1; Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Gal-beta-) called the H antigen which is an essential substrate for the final step in the soluble A and B antigen synthesis pathway. Belongs to the glycosyltransferase 11 family. (366 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1181 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
TACR1Tachykinin receptor 1; Belongs to the G-protein coupled receptor 1 family. (407 aa)
DUSP10Dual specificity phosphatase 10. (399 aa)
MCCMCC regulator of WNT signaling pathway. (1015 aa)
KRIT1Uncharacterized protein. (736 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
TSTA3Tissue specific transplantation antigen P35B. (344 aa)
HSPB1Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (205 aa)
ETS1ETS proto-oncogene 1, transcription factor. (485 aa)
PTPN23Protein tyrosine phosphatase non-receptor type 23. (1630 aa)
TDGF1Growth factor; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. (188 aa)
EPB41L4BErythrocyte membrane protein band 4.1 like 4B. (825 aa)
DOCK5Dedicator of cytokinesis 5; Belongs to the DOCK family. (1870 aa)
RREB1Ras responsive element binding protein 1. (1739 aa)
G3QPK5_GORGOTransforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
ANXA1Annexin. (346 aa)
MAP2K5Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (448 aa)
ROCK2Uncharacterized protein; Belongs to the protein kinase superfamily. (460 aa)
ADIPOR1Adiponectin receptor 1. (375 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (153 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1183 aa)
EVLEnah/Vasp-like; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (418 aa)
GDF2Growth differentiation factor 2. (429 aa)
G3QT76_GORGOTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
ADAM9ADAM metallopeptidase domain 9. (819 aa)
GATA2GATA binding protein 2. (480 aa)
GATA3GATA binding protein 3. (444 aa)
MEOX2Mesenchyme homeobox 2. (303 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1319 aa)
RAB25RAB25, member RAS oncogene family. (213 aa)
PTPRGProtein tyrosine phosphatase receptor type G. (1445 aa)
G3QVG0_GORGOBasigin (Ok blood group). (386 aa)
AAMPAngio associated migratory cell protein. (434 aa)
NF1Neurofibromin 1. (2811 aa)
G3QVZ5_GORGOHyaluronidase. (435 aa)
G3QW59_GORGOGln-synt_C domain-containing protein. (325 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
G3QWN1_GORGOSynaptojanin 2 binding protein. (145 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (837 aa)
SP100Nuclear autoantigen Sp-100; Together with PML, this tumor suppressor is a major constituent of the PML bodies, a subnuclear organelle involved in a large number of physiological processes including cell growth, differentiation and apoptosis. Functions as a transcriptional coactivator of ETS1 and ETS2. Under certain conditions, it may also act as a corepressor of ETS1 preventing its binding to DNA. Through the regulation of ETS1 it may play a role in angiogenesis, controlling endothelial cell motility and invasion. Through interaction with the MRN complex it may be involved in the regul [...] (209 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa)
RHOJRas homolog family member J. (214 aa)
EPHA2EPH receptor A2. (876 aa)
PDCD10Programmed cell death 10. (212 aa)
MARVELD3MARVEL domain containing 3. (410 aa)
MMRN2Multimerin 2. (838 aa)
G3R1H9_GORGOApolipoprotein H. (286 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (599 aa)
G3R1K1_GORGOEphrin A1; Belongs to the ephrin family. (205 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (926 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1041 aa)
ALOX12Arachidonate 12-lipoxygenase, 12S type. (663 aa)
NOTCH1Uncharacterized protein. (1606 aa)
SRPX2Sushi repeat containing protein X-linked 2. (465 aa)
ANGPT2Angiopoietin 2. (496 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (422 aa)
SASH1SAM and SH3 domain containing 1. (1190 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
JUPJunction plakoglobin. (745 aa)
SIRT1Sirtuin 1. (751 aa)
ANXA3Annexin. (325 aa)
G3R4E1_GORGOForkhead box P1. (693 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1225 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2520 aa)
GADD45AGrowth arrest and DNA damage inducible alpha. (165 aa)
G3R5K0_GORGOMitogen-activated protein kinase kinase kinase kinase 4. (1190 aa)
AMOTAngiomotin. (1086 aa)
SEMA5ASemaphorin 5A. (1041 aa)
G3R755_GORGODnaJ heat shock protein family (Hsp40) member A4. (390 aa)
ATP5F1BATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (529 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (832 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
TACSTD2Tumor associated calcium signal transducer 2. (323 aa)
CTSHCathepsin H; Belongs to the peptidase C1 family. (335 aa)
G3R9L0_GORGOPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family. (1072 aa)
G3RA25_GORGOSp1 transcription factor. (786 aa)
WNT7AProtein Wnt-7a; Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta- catenin signaling pathway (By similarity). Plays an important role in embryonic development, including dorsal versus ventral patterning during limb development, skeleton development and urogenital tract development. Required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation (By similarity). Required for normal, sexually dimorphic development of the Mullerian ducts, and for normal fertility in both sexes. Required for normal [...] (345 aa)
ARSJArylsulfatase family member J. (599 aa)
G3RAC9_GORGOVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (395 aa)
PLK2Serine/threonine-protein kinase PLK. (685 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
RHOAUncharacterized protein. (179 aa)
SMOC2SPARC related modular calcium binding 2. (457 aa)
GAB4GRB2 associated binding protein family member 4. (575 aa)
FGFR1Fibroblast growth factor receptor. (820 aa)
ADAM17ADAM metallopeptidase domain 17. (824 aa)
BMPERBMP binding endothelial regulator. (685 aa)
EDN1Endothelin 1. (212 aa)
G3RC81_GORGOF-box and WD repeat domain containing 9. (478 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1066 aa)
MMP9Matrix metallopeptidase 9. (707 aa)
CXCL13C-X-C motif chemokine. (109 aa)
PTPRRProtein tyrosine phosphatase receptor type R. (657 aa)
RAB11ARAB11A, member RAS oncogene family. (216 aa)
VIL1Villin 1. (827 aa)
G3RF44_GORGOForkhead box C2. (442 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1886 aa)
PROX1Prospero homeobox 1. (737 aa)
IRS2Insulin receptor substrate 2. (1220 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (220 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
GRNGranulin precursor. (593 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
TEKTEK receptor tyrosine kinase. (1124 aa)
CALRCalreticulin. (417 aa)
FGFBP1Fibroblast growth factor binding protein 1. (234 aa)
SPARCSecreted protein acidic and cysteine rich. (303 aa)
CCBE1Collagen and calcium binding EGF domains 1. (406 aa)
HDAC7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1008 aa)
PRCPProlylcarboxypeptidase. (517 aa)
RIN2Ras and Rab interactor 2. (939 aa)
NOS3Nitric oxide synthase 3. (997 aa)
ANGPT4Angiopoietin 4. (503 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
VASH1Vasohibin 1. (365 aa)
G3RLN8_GORGOSignal transducer and activator of transcription. (652 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (527 aa)
PATZ1POZ/BTB and AT hook containing zinc finger 1. (687 aa)
SOX9SRY-box transcription factor 9. (509 aa)
G3RNB7_GORGOUncharacterized protein. (661 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
CAPN7Calpain 7; Belongs to the peptidase C2 family. (772 aa)
SRCTyrosine-protein kinase. (542 aa)
RTN4Reticulon. (1192 aa)
PIK3C2APhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1686 aa)
G3RSQ1_GORGOLegumain. (433 aa)
HDAC5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1122 aa)
RGCCRegulator of cell cycle. (137 aa)
HRGHistidine rich glycoprotein. (540 aa)
G3RXP9_GORGONuclear receptor subfamily 2 group F member 2. (414 aa)
G3RXW1_GORGOProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (372 aa)
ZNF580Zinc finger protein 580. (172 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
CEACAM1Carcinoembryonic antigen related cell adhesion molecule 1. (525 aa)
G3S2A2_GORGOCaspase recruitment domain family member 10. (1028 aa)
ANGPT1Angiopoietin 1. (498 aa)
MAPRE2Microtubule associated protein RP/EB family member 2. (327 aa)
PFN2Profilin; Belongs to the profilin family. (188 aa)
TBXA2RThromboxane A2 receptor; Belongs to the G-protein coupled receptor 1 family. (343 aa)
G3S6W7_GORGOThymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (44 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa)
CD40CD40 molecule. (277 aa)
MAP3K3Mitogen-activated protein kinase kinase kinase 3. (657 aa)
HDAC9Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1066 aa)
ENSGGOP00000024523annotation not available (408 aa)
PDPK1Protein kinase domain-containing protein. (347 aa)
ARSIArylsulfatase family member I. (569 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
FBXW7F-box and WD repeat domain containing 7. (707 aa)
NUS1NUS1 dehydrodolichyl diphosphate synthase subunit. (293 aa)
HMGB1Uncharacterized protein. (215 aa)
STC1Stanniocalcin 1. (247 aa)
G3SGV8_GORGOGln-synt_C domain-containing protein. (299 aa)
G3SIC3_GORGOUncharacterized protein. (337 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
G3SIL0_GORGOAdhesion G protein-coupled receptor B1; Belongs to the G-protein coupled receptor 2 family. (1570 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (850 aa)
KLF4Kruppel like factor 4. (479 aa)
GLULGlutamine synthetase. (373 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
ENSGGOP00000029090Uncharacterized protein. (195 aa)
DCNDecorin; May affect the rate of fibrils formation. (359 aa)
RHOBRas homolog family member B. (196 aa)
SLIT2Slit guidance ligand 2. (1542 aa)
MACF1Uncharacterized protein. (7590 aa)
ENSGGOP00000031261Myocyte enhancer factor 2C. (483 aa)
ENSGGOP00000031306Uncharacterized protein. (92 aa)
DAB2IPDAB2 interacting protein. (1155 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
ENSGGOP00000032639Uncharacterized protein. (387 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (840 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (258 aa)
GPIGlucose-6-phosphate isomerase; Belongs to the GPI family. (573 aa)
GLIPR2GLI pathogenesis related 2; Belongs to the CRISP family. (165 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (600 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
SPRED1Sprouty related EVH1 domain containing 1. (444 aa)
RAC1Rac family small GTPase 1. (211 aa)
ENSGGOP00000034961annotation not available (92 aa)
ENSGGOP00000036783Ectonucleotide pyrophosphatase/phosphodiesterase 2. (915 aa)
ARSBArylsulfatase B. (535 aa)
ENSGGOP00000039174Uncharacterized protein. (417 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1042 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (200 aa)
ATP5F1AATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (576 aa)
ENSGGOP00000040217Uncharacterized protein. (371 aa)
ENSGGOP00000040417Profilin; Belongs to the profilin family. (122 aa)
ENSGGOP00000041051Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family. (1242 aa)
C5H5orf30Chromosome 5 open reading frame 30. (206 aa)
ENSGGOP00000041427Cytoplasmic linker associated protein 1. (1538 aa)
RRASRAS related. (218 aa)
METHepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1409 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
ENSGGOP00000042002Uncharacterized protein. (476 aa)
CCR6C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (377 aa)
CIB1Calcium and integrin binding 1. (235 aa)
ENSGGOP00000042328CFC domain-containing protein. (163 aa)
HAS2Hyaluronan synthase 2. (552 aa)
SP100-2SP100 nuclear antigen. (885 aa)
ENSGGOP00000042865EGF-like domain-containing protein. (158 aa)
ENSGGOP00000043386Uncharacterized protein. (1478 aa)
PATZ1-2C2H2-type domain-containing protein. (145 aa)
ENSGGOP00000043921P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (395 aa)
ADAMTS9ADAM metallopeptidase with thrombospondin type 1 motif 9. (1896 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa)
PTNPleiotrophin. (172 aa)
STARD13StAR related lipid transfer domain containing 13. (1113 aa)
ENSGGOP00000045523Uncharacterized protein. (281 aa)
ENSGGOP00000045621Uncharacterized protein. (252 aa)
ENSGGOP00000045937Protein tyrosine phosphatase receptor type M. (1379 aa)
HMOX1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (289 aa)
SCARB1Scavenger receptor class B member 1; Belongs to the CD36 family. (509 aa)
ENSGGOP00000046735Non-specific serine/threonine protein kinase. (524 aa)
JCADJunctional cadherin 5 associated. (1359 aa)
ENSGGOP00000048202Uncharacterized protein. (210 aa)
HDAC6Histone deacetylase 6. (1218 aa)
ENSGGOP00000049938Uncharacterized protein. (177 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa)
THBS1Thrombospondin 1. (1173 aa)
BCAS3BCAS3 microtubule associated cell migration factor. (950 aa)
VEGFCPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (230 aa)
EMP2Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (167 aa)
AGTR2Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. (363 aa)
ATP2B4-2Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (554 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (916 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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