(59 nodes) ER to Golgi transport vesicle membrane network (Gorilla gorilla)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CNIH3	Cornichon family AMPA receptor auxiliary protein 3. (160 aa)
	G3QEJ0_GORGO	Major histocompatibility complex, class II, DR beta 1. (265 aa)
	SEC23A	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (765 aa)
	SEC24D	SEC24 homolog D, COPII coat complex component. (1033 aa)
	FOLR1	Folate receptor alpha. (257 aa)
	SEC24C	Uncharacterized protein. (1094 aa)
	1C03_GORGO	Class I histocompatibility antigen, Gogo-C*0202 alpha chain; Involved in the presentation of foreign antigens to the immune system. (379 aa)
	LMAN1	Lectin, mannose binding 1. (510 aa)
	KLHL12	Kelch like family member 12. (568 aa)
	CNIH2	Cornichon family AMPA receptor auxiliary protein 2. (160 aa)
	G3R317_GORGO	Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (254 aa)
	SEC13	SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (368 aa)
	SEC16A	Protein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. (2345 aa)
	SEC24A	SEC24 homolog A, COPII coat complex component. (1093 aa)
	G3R7K0_GORGO	SEC31 homolog A, COPII coat complex component. (1098 aa)
	G3R7S6_GORGO	CD74 molecule. (296 aa)
	SREBF2	Sterol regulatory element binding transcription factor 2. (1146 aa)
	MCFD2	Multiple coagulation factor deficiency 2. (146 aa)
	STX17	Syntaxin 17; Belongs to the syntaxin family. (302 aa)
	G3QFY0_GORGO	Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family. (260 aa)
	G3RCR2_GORGO	Major histocompatibility complex, class II, DP beta 1. (258 aa)
	SEC31B	SEC31 homolog B, COPII coat complex component. (1166 aa)
	VMA21	Vacuolar ATPase assembly integral membrane protein VMA21; Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum. (156 aa)
	PEF1	Penta-EF-hand domain containing 1. (284 aa)
	G3RKH5_GORGO	Uncharacterized protein. (125 aa)
	G3RLP2_GORGO	Protein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. (1059 aa)
	G3RPG3_GORGO	Major histocompatibility complex, class II, DQ beta 1. (261 aa)
	TMED10	Transmembrane p24 trafficking protein 10. (219 aa)
	SAR1B	Uncharacterized protein. (130 aa)
	SEC24B	SEC24 homolog B, COPII coat complex component. (1248 aa)
	G3S117_GORGO	Major histocompatibility complex, class II, DR beta 5. (266 aa)
	AREG	EGF-like domain-containing protein. (274 aa)
	1OKO_GORGO	Class I histocompatibility antigen, Gogo-OKO alpha chain; Involved in the presentation of foreign antigens to the immune system. (365 aa)
	SAR1A	Secretion associated Ras related GTPase 1A; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
	G3S8P9_GORGO	Major histocompatibility complex, class II, DQ alpha 1; Belongs to the MHC class II family. (256 aa)
	VTI1B	Vesicle transport through interaction with t-SNAREs 1B. (232 aa)
	G3SBN1_GORGO	USO1 vesicle transport factor. (948 aa)
	SEC23B	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (767 aa)
	G3SI24_GORGO	Uncharacterized protein. (212 aa)
	G3SJ91_GORGO	Major histocompatibility complex, class II, DQ beta 2. (264 aa)
	TMED2	Transmembrane p24 trafficking protein 2. (208 aa)
	CD59	UPAR/Ly6 domain-containing protein. (130 aa)
	TMED7	GOLD domain-containing protein. (155 aa)
	ENSGGOP00000033024	Longin domain-containing protein; Belongs to the synaptobrevin family. (170 aa)
	SEC23IP	SEC23 interacting protein. (1025 aa)
	SCAP	SSD domain-containing protein. (338 aa)
	ENSGGOP00000038147	Cornichon family AMPA receptor auxiliary protein 1. (160 aa)
	ENSGGOP00000038870	t-SNARE coiled-coil homology domain-containing protein. (210 aa)
	STX5	Syntaxin 5; Belongs to the syntaxin family. (366 aa)
	GOSR2	Uncharacterized protein. (257 aa)
	GRIA1	Glutamate ionotropic receptor AMPA type subunit 1. (916 aa)
	TGFA	Transforming growth factor alpha. (166 aa)
	ENSGGOP00000045150	GOLD domain-containing protein. (205 aa)
	ENSGGOP00000045173	Uncharacterized protein. (102 aa)
	ENSGGOP00000047484	BTB domain-containing protein. (535 aa)
	VTI1A	Vesicle transport through interaction with t-SNAREs 1A. (217 aa)
	ENSGGOP00000050576	Uncharacterized protein. (168 aa)
	ENSGGOP00000050647	Uncharacterized protein; Belongs to the synaptobrevin family. (214 aa)
	SREBF1	Sterol regulatory element binding transcription factor 1. (1177 aa)

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
1C03_GORGO	1OKO_GORGO	ENSGGOP00000006482	ENSGGOP00000022475	Class I histocompatibility antigen, Gogo-C*0202 alpha chain; Involved in the presentation of foreign antigens to the immune system.	Class I histocompatibility antigen, Gogo-OKO alpha chain; Involved in the presentation of foreign antigens to the immune system.	0.669
1C03_GORGO	G3QEJ0_GORGO	ENSGGOP00000006482	ENSGGOP00000000687	Class I histocompatibility antigen, Gogo-C*0202 alpha chain; Involved in the presentation of foreign antigens to the immune system.	Major histocompatibility complex, class II, DR beta 1.	0.571
1C03_GORGO	G3QFY0_GORGO	ENSGGOP00000006482	ENSGGOP00000013291	Class I histocompatibility antigen, Gogo-C*0202 alpha chain; Involved in the presentation of foreign antigens to the immune system.	Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family.	0.598
1C03_GORGO	G3R317_GORGO	ENSGGOP00000006482	ENSGGOP00000009633	Class I histocompatibility antigen, Gogo-C*0202 alpha chain; Involved in the presentation of foreign antigens to the immune system.	Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family.	0.585
1C03_GORGO	G3R7S6_GORGO	ENSGGOP00000006482	ENSGGOP00000011421	Class I histocompatibility antigen, Gogo-C*0202 alpha chain; Involved in the presentation of foreign antigens to the immune system.	CD74 molecule.	0.413
1C03_GORGO	G3RCR2_GORGO	ENSGGOP00000006482	ENSGGOP00000013296	Class I histocompatibility antigen, Gogo-C*0202 alpha chain; Involved in the presentation of foreign antigens to the immune system.	Major histocompatibility complex, class II, DP beta 1.	0.571
1C03_GORGO	G3RPG3_GORGO	ENSGGOP00000006482	ENSGGOP00000017683	Class I histocompatibility antigen, Gogo-C*0202 alpha chain; Involved in the presentation of foreign antigens to the immune system.	Major histocompatibility complex, class II, DQ beta 1.	0.571
1C03_GORGO	G3S117_GORGO	ENSGGOP00000006482	ENSGGOP00000021762	Class I histocompatibility antigen, Gogo-C*0202 alpha chain; Involved in the presentation of foreign antigens to the immune system.	Major histocompatibility complex, class II, DR beta 5.	0.571
1C03_GORGO	G3S8P9_GORGO	ENSGGOP00000006482	ENSGGOP00000024462	Class I histocompatibility antigen, Gogo-C*0202 alpha chain; Involved in the presentation of foreign antigens to the immune system.	Major histocompatibility complex, class II, DQ alpha 1; Belongs to the MHC class II family.	0.603
1C03_GORGO	G3SJ91_GORGO	ENSGGOP00000006482	ENSGGOP00000028181	Class I histocompatibility antigen, Gogo-C*0202 alpha chain; Involved in the presentation of foreign antigens to the immune system.	Major histocompatibility complex, class II, DQ beta 2.	0.571
1OKO_GORGO	1C03_GORGO	ENSGGOP00000022475	ENSGGOP00000006482	Class I histocompatibility antigen, Gogo-OKO alpha chain; Involved in the presentation of foreign antigens to the immune system.	Class I histocompatibility antigen, Gogo-C*0202 alpha chain; Involved in the presentation of foreign antigens to the immune system.	0.669
1OKO_GORGO	G3QEJ0_GORGO	ENSGGOP00000022475	ENSGGOP00000000687	Class I histocompatibility antigen, Gogo-OKO alpha chain; Involved in the presentation of foreign antigens to the immune system.	Major histocompatibility complex, class II, DR beta 1.	0.634
1OKO_GORGO	G3QFY0_GORGO	ENSGGOP00000022475	ENSGGOP00000013291	Class I histocompatibility antigen, Gogo-OKO alpha chain; Involved in the presentation of foreign antigens to the immune system.	Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family.	0.646
1OKO_GORGO	G3R317_GORGO	ENSGGOP00000022475	ENSGGOP00000009633	Class I histocompatibility antigen, Gogo-OKO alpha chain; Involved in the presentation of foreign antigens to the immune system.	Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family.	0.643
1OKO_GORGO	G3R7S6_GORGO	ENSGGOP00000022475	ENSGGOP00000011421	Class I histocompatibility antigen, Gogo-OKO alpha chain; Involved in the presentation of foreign antigens to the immune system.	CD74 molecule.	0.473
1OKO_GORGO	G3RCR2_GORGO	ENSGGOP00000022475	ENSGGOP00000013296	Class I histocompatibility antigen, Gogo-OKO alpha chain; Involved in the presentation of foreign antigens to the immune system.	Major histocompatibility complex, class II, DP beta 1.	0.631
1OKO_GORGO	G3RPG3_GORGO	ENSGGOP00000022475	ENSGGOP00000017683	Class I histocompatibility antigen, Gogo-OKO alpha chain; Involved in the presentation of foreign antigens to the immune system.	Major histocompatibility complex, class II, DQ beta 1.	0.634
1OKO_GORGO	G3S117_GORGO	ENSGGOP00000022475	ENSGGOP00000021762	Class I histocompatibility antigen, Gogo-OKO alpha chain; Involved in the presentation of foreign antigens to the immune system.	Major histocompatibility complex, class II, DR beta 5.	0.649
1OKO_GORGO	G3S8P9_GORGO	ENSGGOP00000022475	ENSGGOP00000024462	Class I histocompatibility antigen, Gogo-OKO alpha chain; Involved in the presentation of foreign antigens to the immune system.	Major histocompatibility complex, class II, DQ alpha 1; Belongs to the MHC class II family.	0.715
1OKO_GORGO	G3SJ91_GORGO	ENSGGOP00000022475	ENSGGOP00000028181	Class I histocompatibility antigen, Gogo-OKO alpha chain; Involved in the presentation of foreign antigens to the immune system.	Major histocompatibility complex, class II, DQ beta 2.	0.612