STRINGSTRING
ITGA2 ITGA2 NRP1 NRP1 PDGFD PDGFD TERT TERT DOCK4 DOCK4 DOCK5 DOCK5 IGF1 IGF1 FGF9 FGF9 CRK CRK PDGFRB PDGFRB ADAMTS1 ADAMTS1 G3QXA0_GORGO G3QXA0_GORGO ITGB3 ITGB3 S100A11 S100A11 DDR2 DDR2 G3R8K9_GORGO G3R8K9_GORGO PDGFB PDGFB IL18 IL18 G3RK95_GORGO G3RK95_GORGO SRC SRC RPS6KB1 RPS6KB1 NR4A3 NR4A3 IGFBP5 IGFBP5 ATP7A ATP7A MDK MDK G3S6B7_GORGO G3S6B7_GORGO BCL2 BCL2 G3SF91_GORGO G3SF91_GORGO ENSGGOP00000028878 ENSGGOP00000028878 DOCK7 DOCK7 XBP1 XBP1 CCN4 CCN4 HAS2 HAS2 ENSGGOP00000048540 ENSGGOP00000048540 LPAR1 LPAR1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1181 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
PDGFDPlatelet derived growth factor D. (370 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1132 aa)
DOCK4Dedicator of cytokinesis 4; Belongs to the DOCK family. (1986 aa)
DOCK5Dedicator of cytokinesis 5; Belongs to the DOCK family. (1870 aa)
IGF1IlGF domain-containing protein. (196 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
ADAMTS1ADAM metallopeptidase with thrombospondin type 1 motif 1. (967 aa)
G3QXA0_GORGOSCY domain-containing protein. (53 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (837 aa)
S100A11Protein S100; Belongs to the S-100 family. (105 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (855 aa)
G3R8K9_GORGOAllograft inflammatory factor 1. (147 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (220 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
G3RK95_GORGOSemaphorin 6D; Belongs to the semaphorin family. (1086 aa)
SRCTyrosine-protein kinase. (542 aa)
RPS6KB1Protein kinase domain-containing protein. (210 aa)
NR4A3Nuclear receptor subfamily 4 group A member 3. (550 aa)
IGFBP5Insulin like growth factor binding protein 5. (272 aa)
ATP7AATPase copper transporting alpha. (1500 aa)
MDKMidkine. (143 aa)
G3S6B7_GORGOPyrimidinergic receptor P2Y6. (328 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
G3SF91_GORGOEF-hand domain-containing protein; Belongs to the S-100 family. (96 aa)
ENSGGOP00000028878Forkhead box O4. (505 aa)
DOCK7Dedicator of cytokinesis 7; Belongs to the DOCK family. (2137 aa)
XBP1BZIP domain-containing protein. (380 aa)
CCN4Cellular communication network factor 4. (368 aa)
HAS2Hyaluronan synthase 2. (552 aa)
ENSGGOP00000048540Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa)
LPAR1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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