11 items (Gorilla gorilla) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	G3RI71_GORGO	NACHT domain-containing protein. (1127 aa)
	NAIP	Uncharacterized protein. (198 aa)
	NOD1	Nucleotide binding oligomerization domain containing 1. (953 aa)
	PGLYRP1	Peptidoglycan-recognition protein; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Involved in innate immunity. (196 aa)
	NOD2	Nucleotide binding oligomerization domain containing 2. (1040 aa)
	SSC5D	Uncharacterized protein. (941 aa)
	TLR2	Toll-like receptor 2; Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). May also promote apoptosis in response to lipoproteins. Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequentl [...] (784 aa)
	NLRC4	NLR family CARD domain containing 4. (1024 aa)
	PGLYRP4	Peptidoglycan recognition protein 4. (373 aa)
	PGLYRP3	Peptidoglycan recognition protein 3. (341 aa)
	PGLYRP2	Peptidoglycan recognition protein 2. (634 aa)

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
G3RI71_GORGO	NLRC4	ENSGGOP00000015360	ENSGGOP00000002707	NACHT domain-containing protein.	NLR family CARD domain containing 4.	0.867
G3RI71_GORGO	NOD1	ENSGGOP00000015360	ENSGGOP00000022426	NACHT domain-containing protein.	Nucleotide binding oligomerization domain containing 1.	0.540
G3RI71_GORGO	NOD2	ENSGGOP00000015360	ENSGGOP00000010525	NACHT domain-containing protein.	Nucleotide binding oligomerization domain containing 2.	0.497
NAIP	NLRC4	ENSGGOP00000042462	ENSGGOP00000002707	Uncharacterized protein.	NLR family CARD domain containing 4.	0.992
NAIP	NOD1	ENSGGOP00000042462	ENSGGOP00000022426	Uncharacterized protein.	Nucleotide binding oligomerization domain containing 1.	0.540
NAIP	NOD2	ENSGGOP00000042462	ENSGGOP00000010525	Uncharacterized protein.	Nucleotide binding oligomerization domain containing 2.	0.497
NLRC4	G3RI71_GORGO	ENSGGOP00000002707	ENSGGOP00000015360	NLR family CARD domain containing 4.	NACHT domain-containing protein.	0.867
NLRC4	NAIP	ENSGGOP00000002707	ENSGGOP00000042462	NLR family CARD domain containing 4.	Uncharacterized protein.	0.992
NLRC4	NOD1	ENSGGOP00000002707	ENSGGOP00000022426	NLR family CARD domain containing 4.	Nucleotide binding oligomerization domain containing 1.	0.513
NLRC4	NOD2	ENSGGOP00000002707	ENSGGOP00000010525	NLR family CARD domain containing 4.	Nucleotide binding oligomerization domain containing 2.	0.738
NLRC4	TLR2	ENSGGOP00000002707	ENSGGOP00000003012	NLR family CARD domain containing 4.	Toll-like receptor 2; Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). May also promote apoptosis in response to lipoproteins. Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequentl [...]	0.506
NOD1	G3RI71_GORGO	ENSGGOP00000022426	ENSGGOP00000015360	Nucleotide binding oligomerization domain containing 1.	NACHT domain-containing protein.	0.540
NOD1	NAIP	ENSGGOP00000022426	ENSGGOP00000042462	Nucleotide binding oligomerization domain containing 1.	Uncharacterized protein.	0.540
NOD1	NLRC4	ENSGGOP00000022426	ENSGGOP00000002707	Nucleotide binding oligomerization domain containing 1.	NLR family CARD domain containing 4.	0.513
NOD1	NOD2	ENSGGOP00000022426	ENSGGOP00000010525	Nucleotide binding oligomerization domain containing 1.	Nucleotide binding oligomerization domain containing 2.	0.876
NOD1	TLR2	ENSGGOP00000022426	ENSGGOP00000003012	Nucleotide binding oligomerization domain containing 1.	Toll-like receptor 2; Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). May also promote apoptosis in response to lipoproteins. Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequentl [...]	0.719
NOD2	G3RI71_GORGO	ENSGGOP00000010525	ENSGGOP00000015360	Nucleotide binding oligomerization domain containing 2.	NACHT domain-containing protein.	0.497
NOD2	NAIP	ENSGGOP00000010525	ENSGGOP00000042462	Nucleotide binding oligomerization domain containing 2.	Uncharacterized protein.	0.497
NOD2	NLRC4	ENSGGOP00000010525	ENSGGOP00000002707	Nucleotide binding oligomerization domain containing 2.	NLR family CARD domain containing 4.	0.738
NOD2	NOD1	ENSGGOP00000010525	ENSGGOP00000022426	Nucleotide binding oligomerization domain containing 2.	Nucleotide binding oligomerization domain containing 1.	0.876