STRINGSTRING
MNAT1 MNAT1 TAF2 TAF2 RPAP2 RPAP2 GTF2F2 GTF2F2 KAT2A KAT2A TAF5 TAF5 ERCC2 ERCC2 ENSGGOP00000050698 ENSGGOP00000050698 RECQL5 RECQL5 POLR2B POLR2B TAF11 TAF11 CCNH CCNH GTF2F1 GTF2F1 GTF2A2 GTF2A2 PEX2 PEX2 ENSGGOP00000043200 ENSGGOP00000043200 ENSGGOP00000042610 ENSGGOP00000042610 PAF1 PAF1 ENSGGOP00000041523 ENSGGOP00000041523 ENSGGOP00000040591 ENSGGOP00000040591 POLR2F POLR2F G3QQ64_GORGO G3QQ64_GORGO POLR2D POLR2D TAF7L TAF7L RPRD1B RPRD1B G3QND7_GORGO G3QND7_GORGO SETD5 SETD5 TAF4B TAF4B G3QMV9_GORGO G3QMV9_GORGO GTF2A1 GTF2A1 ENSGGOP00000040367 ENSGGOP00000040367 TAF10 TAF10 ENSGGOP00000037665 ENSGGOP00000037665 ENSGGOP00000037296 ENSGGOP00000037296 TBPL1 TBPL1 ENSGGOP00000036704 ENSGGOP00000036704 MYO6 MYO6 ENSGGOP00000034792 ENSGGOP00000034792 RPRD1A RPRD1A ENSGGOP00000033816 ENSGGOP00000033816 ENSGGOP00000033175 ENSGGOP00000033175 TAF1 TAF1 USP22 USP22 CDC73 CDC73 ENY2 ENY2 ENSGGOP00000030596 ENSGGOP00000030596 ENSGGOP00000030375 ENSGGOP00000030375 ENSGGOP00000029268 ENSGGOP00000029268 G3SH53_GORGO G3SH53_GORGO TCEA1 TCEA1 ATXN7 ATXN7 GTF2E1 GTF2E1 TAF8 TAF8 TAF4 TAF4 TAF9B TAF9B TAF6 TAF6 G3QK95_GORGO G3QK95_GORGO MMS19 MMS19 GTF2E2 GTF2E2 G3RZJ6_GORGO G3RZJ6_GORGO G3RXY3_GORGO G3RXY3_GORGO GTF2B GTF2B POLR2J POLR2J POLR2C POLR2C GTF2H5 GTF2H5 POLR2K POLR2K TAF5L TAF5L GTF2H1 GTF2H1 TAF3 TAF3 POLR2I POLR2I ERCC3 ERCC3 POLR2A POLR2A TADA3 TADA3 GTF2H4 GTF2H4 RTF1 RTF1 CDK7 CDK7 STON1 STON1 TBP TBP TAF6L TAF6L POLR2G POLR2G WDR61 WDR61 CTR9 CTR9 G3R6M6_GORGO G3R6M6_GORGO ATXN7L3 ATXN7L3 POLR2L POLR2L TAF13 TAF13 GTF2H3 GTF2H3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
TAF2TATA-box binding protein associated factor 2. (1199 aa)
RPAP2RNA polymerase II associated protein 2. (612 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
KAT2AHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa)
TAF5Uncharacterized protein. (610 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (810 aa)
ENSGGOP00000050698Uncharacterized protein. (233 aa)
RECQL5RecQ like helicase 5. (1016 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
TAF11TATA-box binding protein associated factor 11. (211 aa)
CCNHCyclin H; Belongs to the cyclin family. (329 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (517 aa)
GTF2A2Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa)
PEX2Peroxisomal biogenesis factor 2. (305 aa)
ENSGGOP00000043200Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3265 aa)
ENSGGOP00000042610Protein kinase domain-containing protein. (322 aa)
PAF1PAF1 homolog, Paf1/RNA polymerase II complex component. (533 aa)
ENSGGOP00000041523Uncharacterized protein. (222 aa)
ENSGGOP00000040591SPT3 homolog, SAGA and STAGA complex component. (328 aa)
POLR2FRNA polymerase II subunit F. (158 aa)
G3QQ64_GORGORegulation of nuclear pre-mRNA domain containing 2. (1421 aa)
POLR2DRNA polymerase II subunit D. (142 aa)
TAF7LTATA-box binding protein associated factor 7 like. (461 aa)
RPRD1BRegulation of nuclear pre-mRNA domain containing 1B. (326 aa)
G3QND7_GORGOUncharacterized protein. (264 aa)
SETD5SET domain containing 5. (1461 aa)
TAF4BTATA-box binding protein associated factor 4b. (862 aa)
G3QMV9_GORGORNA_pol_L_2 domain-containing protein. (124 aa)
GTF2A1General transcription factor IIA subunit 1. (370 aa)
ENSGGOP00000040367Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (91 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)
ENSGGOP00000037665TFIID_20kDa domain-containing protein. (213 aa)
ENSGGOP00000037296TFIIF_beta domain-containing protein. (102 aa)
TBPL1TATA-box binding protein like 1. (186 aa)
ENSGGOP00000036704Uncharacterized protein. (58 aa)
MYO6Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1290 aa)
ENSGGOP00000034792Uncharacterized protein. (55 aa)
RPRD1ARegulation of nuclear pre-mRNA domain containing 1A. (312 aa)
ENSGGOP00000033816RNA_pol_L_2 domain-containing protein. (173 aa)
ENSGGOP00000033175TFIID_NTD2 domain-containing protein. (294 aa)
TAF1Transcription initiation factor TFIID subunit. (1927 aa)
USP22Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (553 aa)
CDC73Cell division cycle 73. (452 aa)
ENY2Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] (101 aa)
ENSGGOP00000030596TFIIA_gamma_N domain-containing protein. (69 aa)
ENSGGOP00000030375RNA_pol_L_2 domain-containing protein. (130 aa)
ENSGGOP00000029268Uncharacterized protein. (93 aa)
G3SH53_GORGOTAFII28 domain-containing protein. (198 aa)
TCEA1Transcription elongation factor A1. (301 aa)
ATXN7SCA7 domain-containing protein. (871 aa)
GTF2E1General transcription factor IIE subunit 1. (439 aa)
TAF8TATA-box binding protein associated factor 8. (337 aa)
TAF4TAFH domain-containing protein. (635 aa)
TAF9BTATA-box binding protein associated factor 9b. (251 aa)
TAF6TATA-box binding protein associated factor 6. (714 aa)
G3QK95_GORGODNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (125 aa)
MMS19MMS19 homolog, cytosolic iron-sulfur assembly component. (1030 aa)
GTF2E2Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (291 aa)
G3RZJ6_GORGOLEO1 homolog, Paf1/RNA polymerase II complex component. (666 aa)
G3RXY3_GORGOTAFII28 domain-containing protein. (183 aa)
GTF2BGeneral transcription factor IIB. (316 aa)
POLR2JRNA_pol_L_2 domain-containing protein. (125 aa)
POLR2CRNA polymerase II subunit C. (275 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
POLR2KRNA polymerase II subunit K. (58 aa)
TAF5LTATA-box binding protein associated factor 5 like. (589 aa)
GTF2H1General transcription factor IIH subunit 1. (548 aa)
TAF3TATA-box binding protein associated factor 3. (773 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1960 aa)
TADA3Transcriptional adaptor 3. (432 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa)
RTF1RTF1 homolog, Paf1/RNA polymerase II complex component. (710 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
STON1Stonin-1; May be involved in the endocytic machinery. (1181 aa)
TBPTATA-box binding protein. (332 aa)
TAF6LTATA-box binding protein associated factor 6 like. (578 aa)
POLR2GRNA polymerase II subunit G. (172 aa)
WDR61WD repeat domain 61. (305 aa)
CTR9CTR9 homolog, Paf1/RNA polymerase II complex component. (1173 aa)
G3R6M6_GORGORNA polymerase II subunit E. (210 aa)
ATXN7L3Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] (354 aa)
POLR2LRNA polymerase II subunit L. (67 aa)
TAF13TATA-box binding protein associated factor 13. (124 aa)
GTF2H3General transcription factor IIH subunit 3. (308 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.