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TAF1 TAF1 CSNK2A1 CSNK2A1 GRK2 GRK2 ENSGGOP00000032040 ENSGGOP00000032040 CDC42BPB CDC42BPB ATF2 ATF2 VRK1 VRK1 LMTK2 LMTK2 ENSGGOP00000030528 ENSGGOP00000030528 CAMK2A CAMK2A TSSK4 TSSK4 OXSR1 OXSR1 STK39 STK39 UMOD UMOD DYRK2 DYRK2 HIPK3 HIPK3 PDPK1 PDPK1 TBK1 TBK1 G3S8D3_GORGO G3S8D3_GORGO MAP3K12 MAP3K12 NLK NLK G3S4N5_GORGO G3S4N5_GORGO G3RXW1_GORGO G3RXW1_GORGO G3RQ88_GORGO G3RQ88_GORGO CHEK1 CHEK1 CLK1 CLK1 MARK2 MARK2 TGFBR2 TGFBR2 PRKCA PRKCA PKN1 PKN1 CDK1 CDK1 DYRK3 DYRK3 DYRK1A DYRK1A PRKD1 PRKD1 MYLK2 MYLK2 TNKS TNKS DYRK4 DYRK4 STK11 STK11 HIPK4 HIPK4 PRKCB PRKCB MTOR MTOR ROCK1 ROCK1 TTK TTK HASPIN HASPIN GSK3B GSK3B G3QTD2_GORGO G3QTD2_GORGO ROCK2 ROCK2 GSK3A GSK3A HIPK2 HIPK2 PRKCD PRKCD G3QGC1_GORGO G3QGC1_GORGO ULK1 ULK1 DCAF1 DCAF1 BCL2 BCL2 SBK1 SBK1 TTBK1 TTBK1 MAPK10 MAPK10 TGFBR1 TGFBR1 CSNK2A2 CSNK2A2 PRKD2 PRKD2 MAPK8 MAPK8 PKM PKM ENSGGOP00000047763 ENSGGOP00000047763 WNK3 WNK3 ENSGGOP00000046735 ENSGGOP00000046735 CAD CAD CDC42BPA CDC42BPA HIPK1 HIPK1 CDK5R1 CDK5R1 ENSGGOP00000043662 ENSGGOP00000043662 ENSGGOP00000043657 ENSGGOP00000043657 ACVR1 ACVR1 CIT CIT MAPK1 MAPK1 ENSGGOP00000039174 ENSGGOP00000039174 LRRK2 LRRK2 DYRK1B DYRK1B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TAF1Transcription initiation factor TFIID subunit. (1927 aa)
CSNK2A1Casein kinase 2 alpha 1; Belongs to the protein kinase superfamily. (391 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (680 aa)
ENSGGOP00000032040Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
CDC42BPBCDC42 binding protein kinase beta; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1691 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
VRK1VRK serine/threonine kinase 1; Belongs to the protein kinase superfamily. (420 aa)
LMTK2Lemur tyrosine kinase 2. (1504 aa)
ENSGGOP00000030528Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (515 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
TSSK4Testis specific serine kinase 4. (338 aa)
OXSR1Protein kinase domain-containing protein. (530 aa)
STK39Serine/threonine kinase 39. (546 aa)
UMODUromodulin. (690 aa)
DYRK2Dual specificity tyrosine phosphorylation regulated kinase 2. (597 aa)
HIPK3Homeodomain interacting protein kinase 3. (1215 aa)
PDPK1Protein kinase domain-containing protein. (347 aa)
TBK1TANK binding kinase 1. (729 aa)
G3S8D3_GORGOCalcium/calmodulin dependent protein kinase II delta. (533 aa)
MAP3K12Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (893 aa)
NLKMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa)
G3S4N5_GORGOCyclin dependent kinase 10. (315 aa)
G3RXW1_GORGOProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (372 aa)
G3RQ88_GORGOProtein kinase domain-containing protein. (187 aa)
CHEK1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (476 aa)
CLK1CDC like kinase 1. (543 aa)
MARK2Non-specific serine/threonine protein kinase. (788 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
PKN1Protein kinase N1. (948 aa)
CDK1Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
DYRK3Dual specificity tyrosine phosphorylation regulated kinase 3. (588 aa)
DYRK1AProtein kinase domain-containing protein. (524 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (832 aa)
MYLK2Myosin light chain kinase 2. (596 aa)
TNKSPoly [ADP-ribose] polymerase. (1327 aa)
DYRK4Protein kinase domain-containing protein. (634 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (433 aa)
HIPK4Homeodomain interacting protein kinase 4. (616 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2520 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
TTKTTK protein kinase. (856 aa)
HASPINHistone H3 associated protein kinase. (798 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (481 aa)
G3QTD2_GORGOProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (3503 aa)
ROCK2Uncharacterized protein; Belongs to the protein kinase superfamily. (460 aa)
GSK3AGlycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (483 aa)
HIPK2Homeodomain interacting protein kinase 2. (1196 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
G3QGC1_GORGOMitogen-activated protein kinase kinase kinase. (884 aa)
ULK1Unc-51 like autophagy activating kinase 1. (983 aa)
DCAF1DDB1 and CUL4 associated factor 1. (1481 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
SBK1Serine/threonine-protein kinase SBK1; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (392 aa)
TTBK1Tau tubulin kinase 1. (1322 aa)
MAPK10Mitogen-activated protein kinase. (551 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (334 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
PKMPyruvate kinase; Belongs to the pyruvate kinase family. (556 aa)
ENSGGOP00000047763WNK lysine deficient protein kinase 1. (2786 aa)
WNK3WNK lysine deficient protein kinase 3. (1800 aa)
ENSGGOP00000046735Non-specific serine/threonine protein kinase. (524 aa)
CADCarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. (2229 aa)
CDC42BPANon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1735 aa)
HIPK1Homeodomain interacting protein kinase 1. (1210 aa)
CDK5R1Cyclin-dependent kinase 5 activator. (307 aa)
ENSGGOP00000043662Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (320 aa)
ENSGGOP00000043657Pyruvate kinase; Belongs to the pyruvate kinase family. (299 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (511 aa)
CITCitron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2075 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
ENSGGOP00000039174Uncharacterized protein. (417 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
DYRK1BDual specificity tyrosine phosphorylation regulated kinase 1B. (661 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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