STRINGSTRING
TOR2A TOR2A PGLYRP1 PGLYRP1 ADM ADM G3R7C4_GORGO G3R7C4_GORGO DEFB1 DEFB1 CCL18 CCL18 CAMP CAMP WFDC10A WFDC10A G3RAL4_GORGO G3RAL4_GORGO CCL28 CCL28 G3RBV4_GORGO G3RBV4_GORGO SLC11A1 SLC11A1 G3RD46_GORGO G3RD46_GORGO FGB FGB CCL20 CCL20 CXCL3 CXCL3 CCL21 CCL21 FGA FGA PF4V1 PF4V1 G3SAQ4_GORGO G3SAQ4_GORGO G3SBB4_GORGO G3SBB4_GORGO G3SBD9_GORGO G3SBD9_GORGO ENSGGOP00000025483 ENSGGOP00000025483 G3SDT0_GORGO G3SDT0_GORGO G3SET6_GORGO G3SET6_GORGO WFDC12 WFDC12 BPIFA1 BPIFA1 G3QF49_GORGO G3QF49_GORGO PI3 PI3 PPBP PPBP G3RXV4_GORGO G3RXV4_GORGO HRG HRG LEAP2 LEAP2 JCHAIN JCHAIN CCL1 CCL1 NPPB NPPB WFDC11 WFDC11 RNASE3 RNASE3 PLA2G6 PLA2G6 G3RJR8_GORGO G3RJR8_GORGO CXCL12 CXCL12 SLPI SLPI DEFA5 DEFA5 WFDC13 WFDC13 PF4 PF4 RPS19 RPS19 CST9L CST9L CALCA CALCA CXCL13 CXCL13 GALP GALP H2BC12 H2BC12 DEFB118 DEFB118 ENSGGOP00000051553 ENSGGOP00000051553 CCL22 CCL22 ENSGGOP00000050208 ENSGGOP00000050208 ENSGGOP00000049719 ENSGGOP00000049719 ENSGGOP00000048920 ENSGGOP00000048920 RARRES2 RARRES2 FAM3A FAM3A REG3G REG3G ENSGGOP00000047246 ENSGGOP00000047246 TAC1 TAC1 ROMO1 ROMO1 ENSGGOP00000046335 ENSGGOP00000046335 ENSGGOP00000046102 ENSGGOP00000046102 ENSGGOP00000046073 ENSGGOP00000046073 ENSGGOP00000045870 ENSGGOP00000045870 ENSGGOP00000045214 ENSGGOP00000045214 CCL11 CCL11 ENSGGOP00000041630 ENSGGOP00000041630 RPL30 RPL30 DEFB126 DEFB126 RNASE7 RNASE7 G3RXM3_GORGO G3RXM3_GORGO ENSGGOP00000038658 ENSGGOP00000038658 ENSGGOP00000037298 ENSGGOP00000037298 CXCL11 CXCL11 TSLP TSLP ENSGGOP00000037086 ENSGGOP00000037086 COLEC11 COLEC11 S100A9 S100A9 PGLYRP4 PGLYRP4 PGLYRP3 PGLYRP3 G3QER9_GORGO G3QER9_GORGO RNASE6 RNASE6 CXCL5 CXCL5 G3SK86_GORGO G3SK86_GORGO G3SK93_GORGO G3SK93_GORGO ENSGGOP00000031506 ENSGGOP00000031506 HTN3 HTN3 ENSGGOP00000033064 ENSGGOP00000033064 IL36RN IL36RN ANG ANG ENSGGOP00000036130 ENSGGOP00000036130 ENSGGOP00000036847 ENSGGOP00000036847 G3QER8_GORGO G3QER8_GORGO HAMP HAMP SPON2 SPON2 CCL17 CCL17 FAU FAU CXCL14 CXCL14 CCL13 CCL13 CCL27 CCL27 WFDC5 WFDC5 REG1B REG1B CXCL1 CXCL1 LGALS3 LGALS3 POMC POMC KNG1 KNG1 CCL8 CCL8 DEFA1B DEFA1B CXCL9 CXCL9 WFDC3 WFDC3 HTN1 HTN1 CCL25 CCL25 G3QRT3_GORGO G3QRT3_GORGO G3QUU9_GORGO G3QUU9_GORGO PLA2G1B PLA2G1B S100A12 S100A12 F2 F2 WFDC9 WFDC9 G3QX42_GORGO G3QX42_GORGO RPL39 RPL39 LTF LTF DCD DCD G3R063_GORGO G3R063_GORGO SFTPD SFTPD LGALS4 LGALS4 CST9 CST9 GAPDH GAPDH CXCL6 CXCL6 NTS NTS CXCL10 CXCL10 TF TF NOD2 NOD2 DEFA4 DEFA4 DEFA6 DEFA6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TOR2ATorsin. (321 aa)
PGLYRP1Peptidoglycan-recognition protein; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Involved in innate immunity. (196 aa)
ADMAdrenomedullin. (185 aa)
G3R7C4_GORGORegenerating family member 3 alpha. (175 aa)
DEFB1Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility. (68 aa)
CCL18C-C motif chemokine. (89 aa)
CAMPCathelicidin antimicrobial peptide; Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity; Belongs to the cathelicidin family. (173 aa)
WFDC10AWAP four-disulfide core domain 10A. (79 aa)
G3RAL4_GORGOMajor histocompatibility complex, class I, E; Belongs to the MHC class I family. (354 aa)
CCL28C-C motif chemokine. (127 aa)
G3RBV4_GORGOSerine protease 3; Belongs to the peptidase S1 family. (302 aa)
SLC11A1Solute carrier family 11 member 1. (550 aa)
G3RD46_GORGOCathepsin G; Belongs to the peptidase S1 family. (255 aa)
FGBFibrinogen beta chain. (491 aa)
CCL20C-C motif chemokine. (96 aa)
CXCL3C-X-C motif chemokine. (107 aa)
CCL21C-C motif chemokine ligand 21. (134 aa)
FGAFibrinogen alpha chain. (866 aa)
PF4V1C-X-C motif chemokine. (104 aa)
G3SAQ4_GORGOBeta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (66 aa)
G3SBB4_GORGORibosomal_L7Ae domain-containing protein. (133 aa)
G3SBD9_GORGODEFSN domain-containing protein. (55 aa)
ENSGGOP00000025483annotation not available (112 aa)
G3SDT0_GORGOHistone H2B; Belongs to the histone H2B family. (126 aa)
G3SET6_GORGOC-X-C motif chemokine. (107 aa)
WFDC12WAP four-disulfide core domain protein 12; Antibacterial protein. Putative acid-stable proteinase inhibitor (By similarity). (110 aa)
BPIFA1BPI fold containing family A member 1. (256 aa)
G3QF49_GORGOAzurocidin 1. (251 aa)
PI3Peptidase inhibitor 3. (117 aa)
PPBPC-X-C motif chemokine. (128 aa)
G3RXV4_GORGOUncharacterized protein. (345 aa)
HRGHistidine rich glycoprotein. (540 aa)
LEAP2Liver enriched antimicrobial peptide 2. (77 aa)
JCHAINJoining chain of multimeric IgA and IgM. (159 aa)
CCL1C-C motif chemokine. (96 aa)
NPPBNatriuretic peptide B. (134 aa)
WFDC11WAP four-disulfide core domain 11. (87 aa)
RNASE3Eosinophil cationic protein; Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity (By similarity). (160 aa)
PLA2G6Phospholipase A2 group VI. (806 aa)
G3RJR8_GORGOUncharacterized protein. (113 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (140 aa)
SLPISecretory leukocyte peptidase inhibitor. (132 aa)
DEFA5Defensin alpha 5. (94 aa)
WFDC13WAP four-disulfide core domain 13. (93 aa)
PF4C-X-C motif chemokine. (101 aa)
RPS19Ribosomal protein S19. (145 aa)
CST9LCystatin 9 like. (146 aa)
CALCACalcitonin related polypeptide alpha. (141 aa)
CXCL13C-X-C motif chemokine. (109 aa)
GALPGalanin like peptide. (116 aa)
H2BC12Histone H2B; Belongs to the histone H2B family. (126 aa)
DEFB118Beta-defensin 118; Has antibacterial activity; Belongs to the beta-defensin family. (123 aa)
ENSGGOP00000051553annotation not available (126 aa)
CCL22C-C motif chemokine. (93 aa)
ENSGGOP00000050208annotation not available (126 aa)
ENSGGOP00000049719Uncharacterized protein. (51 aa)
ENSGGOP00000048920Ribosomal_L7Ae domain-containing protein. (93 aa)
RARRES2Retinoic acid receptor responder 2. (163 aa)
FAM3AFamily with sequence similarity 3 member A. (244 aa)
REG3GRegenerating family member 3 gamma. (175 aa)
ENSGGOP00000047246annotation not available (97 aa)
TAC1Tachykinin precursor 1. (129 aa)
ROMO1Reactive oxygen species modulator 1. (79 aa)
ENSGGOP00000046335Uncharacterized protein. (118 aa)
ENSGGOP00000046102Small proline rich protein 2A. (72 aa)
ENSGGOP00000046073Protein S100; Belongs to the S-100 family. (101 aa)
ENSGGOP00000045870Uncharacterized protein. (108 aa)
ENSGGOP00000045214Fib_alpha domain-containing protein. (288 aa)
CCL11C-C motif chemokine. (97 aa)
ENSGGOP00000041630Uncharacterized protein. (75 aa)
RPL30Ribosomal_L7Ae domain-containing protein. (115 aa)
DEFB126Beta-defensin 126; Highly glycosylated atypical beta-defensin involved in several aspects of sperm function. Facilitates sperm transport in the female reproductive tract and contributes to sperm protection against immunodetection; both functions are probably implicating the negative surface charge provided by its O-linked oligosaccharides in the sperm glycocalyx. Involved in binding of sperm to oviductal epithelial cells to form a sperm reservoir until ovulation. Release from the sperm surface during capacitation and ovaluation by an elevation of oviductal fluid pH is unmasking other s [...] (111 aa)
RNASE7Ribonuclease A family member 7; Belongs to the pancreatic ribonuclease family. (156 aa)
G3RXM3_GORGOHistone H2B; Belongs to the histone H2B family. (126 aa)
ENSGGOP00000038658ANK_REP_REGION domain-containing protein. (398 aa)
ENSGGOP00000037298Uncharacterized protein. (51 aa)
CXCL11C-X-C motif chemokine. (94 aa)
TSLPThymic stromal lymphopoietin. (159 aa)
ENSGGOP00000037086Defensin_propep domain-containing protein; Belongs to the alpha-defensin family. (72 aa)
COLEC11Collectin subfamily member 11. (285 aa)
S100A9Protein S100; Belongs to the S-100 family. (114 aa)
PGLYRP4Peptidoglycan recognition protein 4. (373 aa)
PGLYRP3Peptidoglycan recognition protein 3. (341 aa)
G3QER9_GORGOElastase, neutrophil expressed; Belongs to the peptidase S1 family. (246 aa)
RNASE6Ribonuclease K6; Ribonuclease which shows a preference for the pyrimidines uridine and cytosine. Has potent antibacterial activity against a range of Gram-positive and Gram-negative bacteria, including P.aeruginosa, A.baumanii, M.luteus, S.aureus, E.faecalis, E.faecium, S.saprophyticus and E.coli. Causes loss of bacterial membrane integrity, and also promotes agglutination of Gram-negative bacteria. Probably contributes to urinary tract sterility. Bactericidal activity is independent of RNase activity. (150 aa)
CXCL5C-X-C motif chemokine. (114 aa)
G3SK86_GORGOS100 calcium binding protein A7 like 2. (106 aa)
G3SK93_GORGOHistone H2B; Belongs to the histone H2B family. (126 aa)
ENSGGOP00000031506DEFENSIN domain-containing protein. (93 aa)
HTN3Histatin 3. (51 aa)
ENSGGOP00000033064Uncharacterized protein. (308 aa)
IL36RNInterleukin-1. (155 aa)
ANGAngiogenin; Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA. Cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs) (By similarity). Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo (By similarity). (147 aa)
ENSGGOP00000036130Uncharacterized protein. (51 aa)
ENSGGOP00000036847Uncharacterized protein. (51 aa)
G3QER8_GORGOProteinase 3; Belongs to the peptidase S1 family. (256 aa)
HAMPHepcidin antimicrobial peptide. (84 aa)
SPON2Spondin 2. (331 aa)
CCL17C-C motif chemokine. (94 aa)
FAU40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family. (136 aa)
CXCL14C-X-C motif chemokine ligand 14. (111 aa)
CCL13C-C motif chemokine. (98 aa)
CCL27SCY domain-containing protein. (112 aa)
WFDC5WAP four-disulfide core domain protein 5; Putative acid-stable proteinase inhibitor. (224 aa)
REG1BRegenerating family member 1 beta. (166 aa)
CXCL1C-X-C motif chemokine. (107 aa)
LGALS3Galectin. (267 aa)
POMCProopiomelanocortin. (267 aa)
KNG1Kininogen 1. (644 aa)
CCL8C-C motif chemokine. (99 aa)
DEFA1BDEFENSIN domain-containing protein. (94 aa)
CXCL9C-X-C motif chemokine. (125 aa)
WFDC3WAP four-disulfide core domain 3. (234 aa)
HTN1Histatin 1. (57 aa)
CCL25C-C motif chemokine ligand 25. (150 aa)
G3QRT3_GORGOGranulysin. (173 aa)
G3QUU9_GORGOProtein S100; Belongs to the S-100 family. (101 aa)
PLA2G1BPhospholipase A(2). (148 aa)
S100A12S100 calcium binding protein A12; Belongs to the S-100 family. (92 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (622 aa)
WFDC9WAP four-disulfide core domain 9. (89 aa)
G3QX42_GORGOBactericidal permeability increasing protein. (487 aa)
RPL39Uncharacterized protein. (51 aa)
LTFLactotransferrin; Belongs to the transferrin family. (711 aa)
DCDDermcidin. (120 aa)
G3R063_GORGOC-X-C motif chemokine. (103 aa)
SFTPDSurfactant protein D. (375 aa)
LGALS4Galectin. (323 aa)
CST9Cystatin 9. (159 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (335 aa)
CXCL6C-X-C motif chemokine. (114 aa)
NTSNeurotensin. (170 aa)
CXCL10C-X-C motif chemokine. (98 aa)
TFTransferrin; Belongs to the transferrin family. (698 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1040 aa)
DEFA4Defensin alpha 4. (97 aa)
DEFA6Defensin alpha 6. (100 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.