STRINGSTRING
G3S9S6_GORGO G3S9S6_GORGO CCN2 CCN2 ENSGGOP00000051399 ENSGGOP00000051399 TGFBR1 TGFBR1 GHR GHR ENSGGOP00000050071 ENSGGOP00000050071 THBS1 THBS1 ENSGGOP00000049743 ENSGGOP00000049743 ENSGGOP00000049563 ENSGGOP00000049563 ENSGGOP00000049122 ENSGGOP00000049122 ENSGGOP00000048403 ENSGGOP00000048403 GHRHR GHRHR ENSGGOP00000046335 ENSGGOP00000046335 NTF3 NTF3 ITGA6 ITGA6 ITGAV ITGAV NTRK3 NTRK3 ENSGGOP00000041668 ENSGGOP00000041668 CEP57 CEP57 ACVR1 ACVR1 EGFR EGFR RHBDF2 RHBDF2 NTRK1 NTRK1 ACVR1C ACVR1C SPINT3 SPINT3 ERBB3 ERBB3 FGFBP3 FGFBP3 API5 API5 IGFBP2 IGFBP2 ENSGGOP00000035808 ENSGGOP00000035808 PCSK6 PCSK6 ENSGGOP00000034632 ENSGGOP00000034632 IL36RN IL36RN ENSGGOP00000034193 ENSGGOP00000034193 ENSGGOP00000032978 ENSGGOP00000032978 ENSGGOP00000032784 ENSGGOP00000032784 SDCBP SDCBP ENSGGOP00000030684 ENSGGOP00000030684 GPC1 GPC1 ENSGGOP00000030302 ENSGGOP00000030302 FGFRL1 FGFRL1 G3SJA5_GORGO G3SJA5_GORGO LTBP2 LTBP2 G3SCJ4_GORGO G3SCJ4_GORGO LTBP3 LTBP3 LTBP4 LTBP4 IL2RA IL2RA IGFBPL1 IGFBPL1 IL10RA IL10RA IGFBP5 IGFBP5 G3RX48_GORGO G3RX48_GORGO G3RTL2_GORGO G3RTL2_GORGO WFIKKN2 WFIKKN2 G3RSU6_GORGO G3RSU6_GORGO G3RRQ8_GORGO G3RRQ8_GORGO INSR INSR FGFR4 FGFR4 G3RP95_GORGO G3RP95_GORGO TGFBR2 TGFBR2 S100A13 S100A13 HAX1 HAX1 LRP2 LRP2 COL3A1 COL3A1 IGFBP7 IGFBP7 FGFBP1 FGFBP1 ACVR2A ACVR2A PDGFB PDGFB RPS19 RPS19 LIFR LIFR G3RFF0_GORGO G3RFF0_GORGO OSMR OSMR NTRK2 NTRK2 CXCL13 CXCL13 A2M A2M KLB KLB SHC1 SHC1 COL1A1 COL1A1 GLG1 GLG1 FGFR1 FGFR1 SCN5A SCN5A IGF1R IGF1R KDR KDR PXDN PXDN G3RAK0_GORGO G3RAK0_GORGO COL4A1 COL4A1 LTBP1 LTBP1 CRIM1 CRIM1 IL1R2 IL1R2 COL5A1 COL5A1 FSTL4 FSTL4 G3R577_GORGO G3R577_GORGO NLRP7 NLRP7 EPHA8 EPHA8 SRPX2 SRPX2 IGFBP4 IGFBP4 G3R2E9_GORGO G3R2E9_GORGO NRP2 NRP2 RPS2 RPS2 FLT1 FLT1 TSKU TSKU NGFR NGFR G3QZ51_GORGO G3QZ51_GORGO FURIN FURIN NRROS NRROS EPHA2 EPHA2 G3QY00_GORGO G3QY00_GORGO KL KL PDGFRB PDGFRB HYAL2 HYAL2 CCN1 CCN1 FLT4 FLT4 ACVRL1 ACVRL1 SORT1 SORT1 EPHA7 EPHA7 IGFALS IGFALS CD36 CD36 COL1A2 COL1A2 G3QRN3_GORGO G3QRN3_GORGO HTRA1 HTRA1 NRDC NRDC IL1RN IL1RN KAZALD1 KAZALD1 NKD2 NKD2 TWSG1 TWSG1 COL2A1 COL2A1 SEC61B SEC61B CD109 CD109 IL6ST IL6ST IL1R1 IL1R1 IGFBP6 IGFBP6 G3QJA0_GORGO G3QJA0_GORGO CHRDL1 CHRDL1 IL2RB IL2RB LRRC32 LRRC32 IGF2R IGF2R NRP1 NRP1 TGFB3 TGFB3 G3QGJ0_GORGO G3QGJ0_GORGO ENG ENG TGFBR3 TGFBR3 FLT3 FLT3 IL6R IL6R
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
G3S9S6_GORGOUncharacterized protein. (333 aa)
CCN2Cellular communication network factor 2. (348 aa)
ENSGGOP00000051399Uncharacterized protein. (449 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
GHRGrowth hormone receptor. (656 aa)
ENSGGOP00000050071FGF1 intracellular binding protein. (384 aa)
THBS1Thrombospondin 1. (1173 aa)
ENSGGOP00000049743Uncharacterized protein. (455 aa)
ENSGGOP00000049563S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (185 aa)
ENSGGOP00000049122Uncharacterized protein. (305 aa)
ENSGGOP00000048403Lep_receptor_Ig domain-containing protein. (92 aa)
GHRHRGrowth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (423 aa)
ENSGGOP00000046335Uncharacterized protein. (118 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (275 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1130 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1002 aa)
NTRK3Tyrosine-protein kinase receptor. (832 aa)
ENSGGOP00000041668Fibroblast growth factor receptor. (808 aa)
CEP57Centrosomal protein 57. (512 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (511 aa)
EGFRReceptor protein-tyrosine kinase. (1205 aa)
RHBDF2Rhomboid 5 homolog 2. (836 aa)
NTRK1Tyrosine-protein kinase receptor. (796 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (443 aa)
SPINT3Serine peptidase inhibitor, Kunitz type 3. (89 aa)
ERBB3Protein kinase domain-containing protein. (593 aa)
FGFBP3Fibroblast growth factor binding protein 3. (258 aa)
API5Apoptosis inhibitor 5. (524 aa)
IGFBP2Uncharacterized protein. (273 aa)
ENSGGOP00000035808Uncharacterized protein. (272 aa)
PCSK6Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (876 aa)
ENSGGOP00000034632Recep_L_domain domain-containing protein. (183 aa)
IL36RNInterleukin-1. (155 aa)
ENSGGOP00000034193Uncharacterized protein. (301 aa)
ENSGGOP00000032978annotation not available (855 aa)
ENSGGOP00000032784Rhomboid domain-containing protein. (855 aa)
SDCBPSyndecan binding protein. (318 aa)
ENSGGOP00000030684Uncharacterized protein. (311 aa)
GPC1Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (533 aa)
ENSGGOP00000030302PDZ domain-containing protein. (258 aa)
FGFRL1Fibroblast growth factor receptor like 1. (539 aa)
G3SJA5_GORGOSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (541 aa)
LTBP2Latent transforming growth factor beta binding protein 2. (1821 aa)
G3SCJ4_GORGOS5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (226 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1285 aa)
LTBP4Latent transforming growth factor beta binding protein 4. (1624 aa)
IL2RAInterleukin 2 receptor subunit alpha. (272 aa)
IGFBPL1Insulin like growth factor binding protein like 1. (278 aa)
IL10RAInterleukin 10 receptor subunit alpha. (578 aa)
IGFBP5Insulin like growth factor binding protein 5. (272 aa)
G3RX48_GORGOS5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (293 aa)
G3RTL2_GORGOVasorin. (673 aa)
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2. (576 aa)
G3RSU6_GORGOUncharacterized protein. (499 aa)
G3RRQ8_GORGOAXL receptor tyrosine kinase. (843 aa)
INSRTyrosine-protein kinase receptor. (1347 aa)
FGFR4Fibroblast growth factor receptor. (802 aa)
G3RP95_GORGOS5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (287 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
S100A13S100 calcium binding protein A13; Belongs to the S-100 family. (98 aa)
HAX1HCLS1-associated protein X-1; Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools. (279 aa)
LRP2LDL receptor related protein 2. (4653 aa)
COL3A1Collagen type III alpha 1 chain. (1466 aa)
IGFBP7Insulin like growth factor binding protein 7. (282 aa)
FGFBP1Fibroblast growth factor binding protein 1. (234 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (220 aa)
RPS19Ribosomal protein S19. (145 aa)
LIFRLIF receptor subunit alpha. (1097 aa)
G3RFF0_GORGOFibronectin type-III domain-containing protein. (369 aa)
OSMROncostatin M receptor. (981 aa)
NTRK2Tyrosine-protein kinase receptor. (767 aa)
CXCL13C-X-C motif chemokine. (109 aa)
A2MAlpha-2-macroglobulin. (1474 aa)
KLBKlotho beta. (1044 aa)
SHC1SHC adaptor protein 1. (584 aa)
COL1A1Collagen type I alpha 1 chain. (1464 aa)
GLG1Golgi glycoprotein 1. (1174 aa)
FGFR1Fibroblast growth factor receptor. (820 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2020 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
PXDNPeroxidasin. (1472 aa)
G3RAK0_GORGOHAP1 N-terminal domain-containing protein. (471 aa)
COL4A1Collagen type IV alpha 1 chain. (1669 aa)
LTBP1Latent transforming growth factor beta binding protein 1. (1719 aa)
CRIM1Cysteine rich transmembrane BMP regulator 1. (925 aa)
IL1R2Interleukin 1 receptor type 2. (398 aa)
COL5A1Collagen type V alpha 1 chain. (1840 aa)
FSTL4Follistatin like 4. (842 aa)
G3R577_GORGOInsulin like growth factor binding protein 1. (259 aa)
NLRP7NLR family pyrin domain containing 7. (1037 aa)
EPHA8EPH receptor A8. (1005 aa)
SRPX2Sushi repeat containing protein X-linked 2. (465 aa)
IGFBP4Insulin like growth factor binding protein 4. (258 aa)
G3R2E9_GORGOUncharacterized protein. (524 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (926 aa)
RPS2Ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family. (293 aa)
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1302 aa)
TSKUTsukushi, small leucine rich proteoglycan. (353 aa)
NGFRNerve growth factor receptor. (427 aa)
G3QZ51_GORGOFibroblast growth factor receptor. (822 aa)
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (794 aa)
NRROSNegative regulator of reactive oxygen species. (692 aa)
EPHA2EPH receptor A2. (876 aa)
G3QY00_GORGOWAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1. (548 aa)
KLUncharacterized protein; Belongs to the glycosyl hydrolase 1 family. (739 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
HYAL2Hyaluronidase. (473 aa)
CCN1Cellular communication network factor 1. (381 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1319 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
SORT1Sortilin. (831 aa)
EPHA7EPH receptor A7. (998 aa)
IGFALSInsulin like growth factor binding protein acid labile subunit. (643 aa)
CD36CD36 molecule; Belongs to the CD36 family. (472 aa)
COL1A2Collagen type I alpha 2 chain. (1366 aa)
G3QRN3_GORGOS5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (273 aa)
HTRA1HtrA serine peptidase 1. (481 aa)
NRDCNardilysin convertase. (1219 aa)
IL1RNInterleukin-1. (180 aa)
KAZALD1Kazal type serine peptidase inhibitor domain 1. (303 aa)
NKD2NKD inhibitor of WNT signaling pathway 2. (451 aa)
TWSG1Twisted gastrulation BMP signaling modulator 1. (223 aa)
COL2A1Collagen type II alpha 1 chain. (1487 aa)
SEC61BProtein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (96 aa)
CD109CD109 molecule. (1446 aa)
IL6STFibronectin type-III domain-containing protein. (329 aa)
IL1R1Interleukin 1 receptor type 1. (569 aa)
IGFBP6Insulin like growth factor binding protein 6. (240 aa)
G3QJA0_GORGOS5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (274 aa)
CHRDL1Chordin like 1. (458 aa)
IL2RBInterleukin 2 receptor subunit beta. (551 aa)
LRRC32Leucine rich repeat containing 32. (662 aa)
IGF2RInsulin like growth factor 2 receptor. (2491 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
G3QGJ0_GORGOCollagen type VI alpha 1 chain. (1026 aa)
ENGEndoglin. (654 aa)
TGFBR3Transforming growth factor beta receptor 3. (860 aa)
FLT3Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (993 aa)
IL6RInterleukin 6 receptor. (468 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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