STRINGSTRING
SMTNL2 SMTNL2 G3QDE1_GORGO G3QDE1_GORGO PPME1 PPME1 BCL2 BCL2 PPP1R3F PPP1R3F STAT6 STAT6 SLC9A1 SLC9A1 SKAP2 SKAP2 CTTNBP2NL CTTNBP2NL SMG7 SMG7 FBXL2 FBXL2 MFHAS1 MFHAS1 VCP VCP G3QL18_GORGO G3QL18_GORGO LGALS3 LGALS3 G3QML2_GORGO G3QML2_GORGO TRAF3 TRAF3 ERBB2 ERBB2 G3QRR1_GORGO G3QRR1_GORGO NEK2 NEK2 KAT2A KAT2A KCNN4 KCNN4 PPP1R3A PPP1R3A G3QSH5_GORGO G3QSH5_GORGO STRN3 STRN3 GRB2 GRB2 G3QTZ7_GORGO G3QTZ7_GORGO DLG4 DLG4 FLT4 FLT4 PTPN1 PTPN1 G3QW36_GORGO G3QW36_GORGO TRAF2 TRAF2 FBXO41 FBXO41 KIF3A KIF3A FOXO1 FOXO1 SH3RF2 SH3RF2 SHOC2 SHOC2 ANAPC5 ANAPC5 CLEC12B CLEC12B CD22 CD22 GRIN3A GRIN3A GNA12 GNA12 G3R3C0_GORGO G3R3C0_GORGO FER FER PAWR PAWR JUP JUP STRN4 STRN4 PDLIM4 PDLIM4 MYOZ2 MYOZ2 ATP2B4 ATP2B4 BOD1 BOD1 SMG5 SMG5 CSK CSK LRRD1 LRRD1 PPP1R10 PPP1R10 EIF2AK3 EIF2AK3 SIRPD SIRPD LILRB4 LILRB4 SKAP1 SKAP1 STX17 STX17 GAB4 GAB4 PPP6R2 PPP6R2 KCNQ1 KCNQ1 FCRL3 FCRL3 MTMR4 MTMR4 ROS1 ROS1 G3REM6_GORGO G3REM6_GORGO CDC27 CDC27 IRS2 IRS2 MVP MVP PPP1R16B PPP1R16B MTMR9 MTMR9 JAK1 JAK1 MASTL MASTL SPHK1 SPHK1 C20H20orf27 C20H20orf27 MYO16 MYO16 CSF1R CSF1R G3RMN5_GORGO G3RMN5_GORGO KIFAP3 KIFAP3 PPP1R11 PPP1R11 SMTNL1 SMTNL1 G3RPL9_GORGO G3RPL9_GORGO ITGA1 ITGA1 G3RRK1_GORGO G3RRK1_GORGO RPS6KB1 RPS6KB1 AP3B1 AP3B1 G3RUI3_GORGO G3RUI3_GORGO IKBKE IKBKE IGBP1 IGBP1 BOD1L1 BOD1L1 AKAP11 AKAP11 FAM71F2 FAM71F2 STAT3 STAT3 FCRL2 FCRL2 SIRPA SIRPA SLC6A3 SLC6A3 PTK2 PTK2 CEACAM1 CEACAM1 AMBRA1 AMBRA1 G3S2M4_GORGO G3S2M4_GORGO PPP6R1 PPP6R1 TCTEX1D4 TCTEX1D4 MAP3K5 MAP3K5 PPP6R3 PPP6R3 G3S5R7_GORGO G3S5R7_GORGO BOD1L2 BOD1L2 TBK1 TBK1 PPP1R3G PPP1R3G HSP90B1 HSP90B1 STAU1 STAU1 VRK3 VRK3 CDH2 CDH2 MTMR3 MTMR3 CD33 CD33 AKAP5 AKAP5 G3SFH3_GORGO G3SFH3_GORGO CDH5 CDH5 SIRPG SIRPG STAT1 STAT1 PPP3CB PPP3CB G3SH76_GORGO G3SH76_GORGO G3SHK6_GORGO G3SHK6_GORGO G3SHM7_GORGO G3SHM7_GORGO ENSGGOP00000028898 ENSGGOP00000028898 ENSGGOP00000029025 ENSGGOP00000029025 ENSGGOP00000029053 ENSGGOP00000029053 ENSGGOP00000029158 ENSGGOP00000029158 ENSGGOP00000030268 ENSGGOP00000030268 ENSGGOP00000030281 ENSGGOP00000030281 ENSGGOP00000030361 ENSGGOP00000030361 ENSGGOP00000031106 ENSGGOP00000031106 DAB2IP DAB2IP PHACTR4 PHACTR4 ENSGGOP00000031909 ENSGGOP00000031909 PPP1R9B PPP1R9B LCK LCK ENSGGOP00000032522 ENSGGOP00000032522 PHACTR3 PHACTR3 PPARG PPARG PPP1R3B PPP1R3B ENSGGOP00000032867 ENSGGOP00000032867 PTPRT PTPRT ENSGGOP00000034103 ENSGGOP00000034103 ENSGGOP00000035506 ENSGGOP00000035506 PPP1CC PPP1CC ANK1 ANK1 ENSGGOP00000037430 ENSGGOP00000037430 ENSGGOP00000037676 ENSGGOP00000037676 CADM4 CADM4 ENSGGOP00000038416 ENSGGOP00000038416 HSF4 HSF4 PPP1R3C PPP1R3C BAD BAD YWHAE YWHAE EGFR EGFR MAP2K7 MAP2K7 MET MET AP3B2 AP3B2 FCRL6 FCRL6 SOD1 SOD1 ENSGGOP00000044020 ENSGGOP00000044020 ENSGGOP00000044113 ENSGGOP00000044113 ENSGGOP00000045489 ENSGGOP00000045489 FBXL20 FBXL20 GTF2F1 GTF2F1 ENSGGOP00000048879 ENSGGOP00000048879 CTNNB1 CTNNB1 ENSGGOP00000049072 ENSGGOP00000049072 MAPK8 MAPK8 IQGAP1 IQGAP1 CDKN1B CDKN1B ADCY8 ADCY8 PIK3R1 PIK3R1 GHR GHR MAPK10 MAPK10 ATP2B4-2 ATP2B4-2 ENSGGOP00000051819 ENSGGOP00000051819
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMTNL2Smoothelin like 2. (461 aa)
G3QDE1_GORGOStriatin. (682 aa)
PPME1Protein phosphatase methylesterase 1; Demethylates proteins that have been reversibly carboxymethylated. (386 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
PPP1R3FProtein phosphatase 1 regulatory subunit 3F. (644 aa)
STAT6Signal transducer and activator of transcription. (847 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
SKAP2Src kinase associated phosphoprotein 2. (359 aa)
CTTNBP2NLCTTNBP2 N-terminal like. (639 aa)
SMG7SMG7 nonsense mediated mRNA decay factor. (1170 aa)
FBXL2F-box and leucine rich repeat protein 2. (423 aa)
MFHAS1Malignant fibrous histiocytoma amplified sequence 1. (1010 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (806 aa)
G3QL18_GORGOUncharacterized protein. (453 aa)
LGALS3Galectin. (267 aa)
G3QML2_GORGOPhosphatase and actin regulator. (580 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (570 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
G3QRR1_GORGOUncharacterized protein. (124 aa)
NEK2NIMA related kinase 2. (445 aa)
KAT2AHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa)
KCNN4Potassium calcium-activated channel subfamily N member 4. (427 aa)
PPP1R3AProtein phosphatase 1 regulatory subunit 3A. (1122 aa)
G3QSH5_GORGOTyrosine-protein kinase. (1124 aa)
STRN3Striatin 3. (739 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
G3QTZ7_GORGOProtein phosphatase 1 regulatory subunit 15A. (682 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (745 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1319 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (435 aa)
G3QW36_GORGOUncharacterized protein. (652 aa)
TRAF2TNF receptor-associated factor. (451 aa)
FBXO41F-box protein 41. (839 aa)
KIF3AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (726 aa)
FOXO1Forkhead box O1. (655 aa)
SH3RF2SH3 domain containing ring finger 2. (729 aa)
SHOC2SHOC2 leucine rich repeat scaffold protein. (582 aa)
ANAPC5Anaphase promoting complex subunit 5. (755 aa)
CLEC12BC-type lectin domain family 12 member B. (276 aa)
CD22B-cell receptor CD22; Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6- linked sialic acid (By similarity). Upon ligand-induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that b [...] (847 aa)
GRIN3AGlutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1115 aa)
GNA12G protein subunit alpha 12. (381 aa)
G3R3C0_GORGOSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
PAWRPro-apoptotic WT1 regulator. (341 aa)
JUPJunction plakoglobin. (745 aa)
STRN4Striatin 4. (760 aa)
PDLIM4PDZ and LIM domain 4. (330 aa)
MYOZ2Myozenin 2. (264 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1225 aa)
BOD1Biorientation of chromosomes in cell division 1. (185 aa)
SMG5SMG5 nonsense mediated mRNA decay factor. (1016 aa)
CSKTyrosine-protein kinase. (450 aa)
LRRD1Leucine rich repeats and death domain containing 1. (860 aa)
PPP1R10Protein phosphatase 1 regulatory subunit 10. (939 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1116 aa)
SIRPDSignal regulatory protein delta. (197 aa)
LILRB4Ig-like domain-containing protein. (342 aa)
SKAP1Src kinase associated phosphoprotein 1. (359 aa)
STX17Syntaxin 17; Belongs to the syntaxin family. (302 aa)
GAB4GRB2 associated binding protein family member 4. (575 aa)
PPP6R2Protein phosphatase 6 regulatory subunit 2. (959 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (676 aa)
FCRL3Fc receptor like 3. (741 aa)
MTMR4Myotubularin related protein 4. (1195 aa)
ROS1Tyrosine-protein kinase receptor. (2347 aa)
G3REM6_GORGOAnaphase promoting complex subunit 7. (496 aa)
CDC27Cell division cycle 27. (705 aa)
IRS2Insulin receptor substrate 2. (1220 aa)
MVPMajor vault protein. (893 aa)
PPP1R16BProtein phosphatase 1 regulatory subunit 16B. (568 aa)
MTMR9Myotubularin related protein 9. (549 aa)
JAK1Tyrosine-protein kinase. (1154 aa)
MASTLMicrotubule associated serine/threonine kinase like. (879 aa)
SPHK1Sphingosine kinase 1. (472 aa)
C20H20orf27Chromosome 20 open reading frame 27. (174 aa)
MYO16Myosin XVI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1887 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa)
G3RMN5_GORGOUncharacterized protein. (383 aa)
KIFAP3Kinesin associated protein 3. (792 aa)
PPP1R11Protein phosphatase 1 regulatory inhibitor subunit 11. (126 aa)
SMTNL1Smoothelin like 1. (494 aa)
G3RPL9_GORGOUncharacterized protein. (326 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1179 aa)
G3RRK1_GORGOUncharacterized protein. (497 aa)
RPS6KB1Protein kinase domain-containing protein. (210 aa)
AP3B1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1094 aa)
G3RUI3_GORGOUncharacterized protein. (156 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (716 aa)
IGBP1Immunoglobulin binding protein 1. (339 aa)
BOD1L1Biorientation of chromosomes in cell division 1 like 1. (3052 aa)
AKAP11A-kinase anchoring protein 11. (1901 aa)
FAM71F2Family with sequence similarity 71 member F2. (300 aa)
STAT3Signal transducer and activator of transcription. (781 aa)
FCRL2Fc receptor like 2. (508 aa)
SIRPASignal regulatory protein alpha. (508 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (599 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
CEACAM1Carcinoembryonic antigen related cell adhesion molecule 1. (525 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1298 aa)
G3S2M4_GORGOUncharacterized protein. (278 aa)
PPP6R1Protein phosphatase 6 regulatory subunit 1. (868 aa)
TCTEX1D4Tctex1 domain containing 4. (220 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1374 aa)
PPP6R3Protein phosphatase 6 regulatory subunit 3. (879 aa)
G3S5R7_GORGOProtein phosphatase 1 regulatory subunit 16A. (527 aa)
BOD1L2Biorientation of chromosomes in cell division 1 like 2. (170 aa)
TBK1TANK binding kinase 1. (729 aa)
PPP1R3GProtein phosphatase 1 regulatory subunit 3G. (358 aa)
HSP90B1Heat shock protein 90 beta family member 1. (814 aa)
STAU1Staufen double-stranded RNA binding protein 1. (585 aa)
VRK3VRK serine/threonine kinase 3. (474 aa)
CDH2Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (886 aa)
MTMR3Myotubularin related protein 3. (1201 aa)
CD33CD33 molecule. (364 aa)
AKAP5A-kinase anchoring protein 5. (427 aa)
G3SFH3_GORGOUncharacterized protein; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (133 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (784 aa)
SIRPGSignal regulatory protein gamma. (354 aa)
STAT1Signal transducer and activator of transcription. (777 aa)
PPP3CBSerine/threonine-protein phosphatase. (524 aa)
G3SH76_GORGOAnaphase promoting complex subunit 4. (708 aa)
G3SHK6_GORGOUncharacterized protein. (508 aa)
G3SHM7_GORGO14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (210 aa)
ENSGGOP0000002889814_3_3 domain-containing protein; Belongs to the 14-3-3 family. (195 aa)
ENSGGOP00000029025Uncharacterized protein. (420 aa)
ENSGGOP00000029053cAMP regulated phosphoprotein 19; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (131 aa)
ENSGGOP00000029158Uncharacterized protein. (42 aa)
ENSGGOP00000030268Uncharacterized protein. (596 aa)
ENSGGOP00000030281Uncharacterized protein. (331 aa)
ENSGGOP00000030361Uncharacterized protein. (275 aa)
ENSGGOP00000031106WD_REPEATS_REGION domain-containing protein. (321 aa)
DAB2IPDAB2 interacting protein. (1155 aa)
PHACTR4Phosphatase and actin regulator. (712 aa)
ENSGGOP00000031909Serine/threonine/tyrosine interacting like 1. (313 aa)
PPP1R9BProtein phosphatase 1 regulatory subunit 9B. (817 aa)
LCKTyrosine-protein kinase. (524 aa)
ENSGGOP0000003252214_3_3 domain-containing protein; Belongs to the 14-3-3 family. (203 aa)
PHACTR3Phosphatase and actin regulator. (559 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
PPP1R3BProtein phosphatase 1 regulatory subunit. (285 aa)
ENSGGOP00000032867Uncharacterized protein. (96 aa)
PTPRTProtein tyrosine phosphatase receptor type T. (1451 aa)
ENSGGOP00000034103Uncharacterized protein. (106 aa)
ENSGGOP00000035506Uncharacterized protein. (91 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (346 aa)
ANK1Ankyrin 1. (1897 aa)
ENSGGOP00000037430Sorting nexin 3. (169 aa)
ENSGGOP00000037676Ankyrin repeat and LEM domain containing 2. (915 aa)
CADM4Cell adhesion molecule 4. (373 aa)
ENSGGOP00000038416DUF3699 domain-containing protein. (462 aa)
HSF4Heat shock transcription factor 4. (498 aa)
PPP1R3CProtein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. (317 aa)
BADBCL2 associated agonist of cell death. (168 aa)
YWHAETyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (255 aa)
EGFRReceptor protein-tyrosine kinase. (1205 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (435 aa)
METHepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1409 aa)
AP3B2AP-3 complex subunit beta. (1101 aa)
FCRL6Uncharacterized protein. (211 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
ENSGGOP00000044020Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (76 aa)
ENSGGOP00000044113Uncharacterized protein. (1081 aa)
ENSGGOP00000045489Ig-like domain-containing protein. (164 aa)
FBXL20F-box and leucine rich repeat protein 20. (438 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (517 aa)
ENSGGOP00000048879Uncharacterized protein. (163 aa)
CTNNB1Catenin beta 1. (781 aa)
ENSGGOP00000049072Protein kinase domain-containing protein. (296 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
IQGAP1IQ motif containing GTPase activating protein 1. (1657 aa)
CDKN1BUncharacterized protein. (205 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (723 aa)
GHRGrowth hormone receptor. (656 aa)
MAPK10Mitogen-activated protein kinase. (551 aa)
ATP2B4-2Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (554 aa)
ENSGGOP00000051819Protein kinase domain-containing protein. (421 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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