STRINGSTRING
HOXA3 HOXA3 HOXA1 HOXA1 SULF2 SULF2 GLI3 GLI3 NRP1 NRP1 MAFB MAFB SERPINE2 SERPINE2 SALL1 SALL1 EDNRA EDNRA DICER1 DICER1 ENSGGOP00000051444 ENSGGOP00000051444 ENSGGOP00000050768 ENSGGOP00000050768 CTNNB1 CTNNB1 GABRA5 GABRA5 TIFAB TIFAB CNGB1 CNGB1 NTF3 NTF3 ENSGGOP00000043337 ENSGGOP00000043337 HOXD3 HOXD3 ENSGGOP00000041960 ENSGGOP00000041960 NTRK1 NTRK1 SULF1 SULF1 ILK ILK SEMA3F SEMA3F DMD DMD ERBB3 ERBB3 PRKCG PRKCG ENSGGOP00000034899 ENSGGOP00000034899 ENSGGOP00000034632 ENSGGOP00000034632 ENSGGOP00000034523 ENSGGOP00000034523 NGF NGF ENSGGOP00000033577 ENSGGOP00000033577 RPL24 RPL24 BDNF BDNF AFG3L2 AFG3L2 SLITRK6 SLITRK6 ITGA4 ITGA4 PHOX2A PHOX2A LPAR1 LPAR1 PLXNA1 PLXNA1 TMEM126A TMEM126A SLC25A46 SLC25A46 G3RTH8_GORGO G3RTH8_GORGO NEUROG1 NEUROG1 G3RK03_GORGO G3RK03_GORGO CITED2 CITED2 SEMA3A SEMA3A G3RF14_GORGO G3RF14_GORGO LRIG1 LRIG1 FBXO45 FBXO45 EPHB1 EPHB1 ATP8B1 ATP8B1 PLXNA3 PLXNA3 EDN1 EDN1 ADARB1 ADARB1 HOXB3 HOXB3 POU4F3 POU4F3 CHD7 CHD7 ECE1 ECE1 DAG1 DAG1 SIX4 SIX4 HOXB2 HOXB2 HOXB1 HOXB1 NPTX1 NPTX1 ISL1 ISL1 NRP2 NRP2 TBX1 TBX1 G3R0V2_GORGO G3R0V2_GORGO HES1 HES1 NGFR NGFR EPHB2 EPHB2 DRGX DRGX SLC24A4 SLC24A4 NKX2-2 NKX2-2 TFAP2A TFAP2A PLXNA4 PLXNA4 CHRNB2 CHRNB2 NAV2 NAV2 G3QTT4_GORGO G3QTT4_GORGO PHOX2B PHOX2B COL25A1 COL25A1 G3QS43_GORGO G3QS43_GORGO G3QRG5_GORGO G3QRG5_GORGO EGR2 EGR2 TCIRG1 TCIRG1 SLC1A3 SLC1A3 RET RET ACKR3 ACKR3 VCAM1 VCAM1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HOXA3Homeobox A3. (443 aa)
HOXA1Homeobox A1. (335 aa)
SULF2Sulfatase 2. (851 aa)
GLI3GLI family zinc finger 3. (1580 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
MAFBMAF bZIP transcription factor B. (323 aa)
SERPINE2Serpin family E member 2; Belongs to the serpin family. (409 aa)
SALL1Spalt like transcription factor 1. (1324 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
DICER1Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. (1922 aa)
ENSGGOP00000051444Uncharacterized protein. (61 aa)
ENSGGOP00000050768Paired box 2. (392 aa)
CTNNB1Catenin beta 1. (781 aa)
GABRA5Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (462 aa)
TIFABTIFA inhibitor. (161 aa)
CNGB1Cyclic nucleotide gated channel subunit beta 1. (1251 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (275 aa)
ENSGGOP00000043337TRASH domain-containing protein. (127 aa)
HOXD3Homeobox D3. (432 aa)
ENSGGOP00000041960TRASH domain-containing protein. (123 aa)
NTRK1Tyrosine-protein kinase receptor. (796 aa)
SULF1Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (883 aa)
ILKIntegrin linked kinase. (535 aa)
SEMA3FSemaphorin 3F; Belongs to the semaphorin family. (785 aa)
DMDDystrophin. (3685 aa)
ERBB3Protein kinase domain-containing protein. (593 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (698 aa)
ENSGGOP00000034899Leucine rich repeats and immunoglobulin like domains 2. (1035 aa)
ENSGGOP00000034632Recep_L_domain domain-containing protein. (183 aa)
ENSGGOP00000034523AAA domain-containing protein; Belongs to the AAA ATPase family. (656 aa)
NGFBeta-nerve growth factor; Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation, differentiation and survival (By similarity). The immature NGF precursor (proNGF) functions as ligand for the heterodimeric receptor formed by SORCS2 and NGFR, and activates cellular signaling cascades that lead to inactivation of RAC1 and/or RAC2, reorganization of the actin cytoskeleton and neuronal growth cone colla [...] (123 aa)
ENSGGOP00000033577TRASH domain-containing protein. (147 aa)
RPL24TRASH domain-containing protein. (243 aa)
BDNFBrain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (329 aa)
AFG3L2AFG3 like matrix AAA peptidase subunit 2. (793 aa)
SLITRK6SLIT and NTRK like family member 6. (841 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1032 aa)
PHOX2APaired like homeobox 2A. (255 aa)
LPAR1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
PLXNA1Plexin A1. (1917 aa)
TMEM126ATransmembrane protein 126A. (195 aa)
SLC25A46Solute carrier family 25 member 46; Belongs to the mitochondrial carrier (TC 2.A.29) family. (418 aa)
G3RTH8_GORGOPOU domain protein. (259 aa)
NEUROG1Neurogenin 1. (237 aa)
G3RK03_GORGOAtonal bHLH transcription factor 7. (152 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa)
SEMA3ASemaphorin 3A; Belongs to the semaphorin family. (771 aa)
G3RF14_GORGOGamma-aminobutyric acid type A receptor beta2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (512 aa)
LRIG1Leucine rich repeats and immunoglobulin like domains 1. (1091 aa)
FBXO45F-box protein 45. (254 aa)
EPHB1EPH receptor B1. (984 aa)
ATP8B1Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1251 aa)
PLXNA3Plexin A3. (1871 aa)
EDN1Endothelin 1. (212 aa)
ADARB1Adenosine deaminase RNA specific B1. (741 aa)
HOXB3Homeobox B3. (427 aa)
POU4F3POU domain protein. (338 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2997 aa)
ECE1Endothelin converting enzyme 1. (758 aa)
DAG1Dystroglycan 1. (894 aa)
SIX4SIX homeobox 4. (677 aa)
HOXB2Homeobox B2. (356 aa)
HOXB1Homeobox B1. (307 aa)
NPTX1Neuronal pentraxin 1. (432 aa)
ISL1ISL LIM homeobox 1. (351 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (926 aa)
TBX1Uncharacterized protein. (311 aa)
G3R0V2_GORGOPhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1248 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
NGFRNerve growth factor receptor. (427 aa)
EPHB2EPH receptor B2. (1113 aa)
DRGXDorsal root ganglia homeobox. (263 aa)
SLC24A4Solute carrier family 24 member 4; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (622 aa)
NKX2-2NK2 homeobox 2. (273 aa)
TFAP2ATranscription factor AP-2 alpha. (439 aa)
PLXNA4Plexin A4. (1854 aa)
CHRNB2Cholinergic receptor nicotinic beta 2 subunit. (502 aa)
NAV2Neuron navigator 2. (2485 aa)
G3QTT4_GORGONeurturin. (197 aa)
PHOX2BPaired like homeobox 2B. (314 aa)
COL25A1Collagen type XXV alpha 1 chain. (654 aa)
G3QS43_GORGORing finger protein 165. (342 aa)
G3QRG5_GORGONeurotrophin 4; Belongs to the NGF-beta family. (210 aa)
EGR2Early growth response 2. (476 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa)
SLC1A3Amino acid transporter. (542 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1114 aa)
ACKR3Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (362 aa)
VCAM1Vascular cell adhesion molecule 1. (739 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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