STRINGSTRING
LRRK1 LRRK1 THPO THPO ZBTB16 ZBTB16 FOS FOS L3MBTL3 L3MBTL3 KMT2E KMT2E GPR183 GPR183 G3QER8_GORGO G3QER8_GORGO ATP5IF1 ATP5IF1 TGFBR3 TGFBR3 GAB3 GAB3 CSF2 CSF2 MYB MYB DHRS2 DHRS2 FLVCR1 FLVCR1 CASP9 CASP9 DCSTAMP DCSTAMP ALAS2 ALAS2 PSEN1 PSEN1 BATF BATF EFNA2 EFNA2 RPS6 RPS6 TESC TESC PIR PIR MFHAS1 MFHAS1 CCL19 CCL19 G3QKG3_GORGO G3QKG3_GORGO CD4 CD4 SH2B3 SH2B3 DNASE2 DNASE2 KLF1 KLF1 INHA INHA G3QN25_GORGO G3QN25_GORGO NOTCH2 NOTCH2 HIPK2 HIPK2 CD109 CD109 FLNA FLNA FARP2 FARP2 RASGRP4 RASGRP4 SLC25A40 SLC25A40 ZBTB46 ZBTB46 G3QQC9_GORGO G3QQC9_GORGO TCIRG1 TCIRG1 CSF3 CSF3 EVI2B EVI2B PAFAH1B1 PAFAH1B1 RCOR1 RCOR1 VPS33A VPS33A DLL1 DLL1 G3QS37_GORGO G3QS37_GORGO IL4 IL4 CLEC1B CLEC1B G3QSH5_GORGO G3QSH5_GORGO TRAF6 TRAF6 G3QT76_GORGO G3QT76_GORGO IFNG IFNG UBA5 UBA5 IFI16 IFI16 GATA2 GATA2 GATA3 GATA3 CLEC5A CLEC5A SPI1 SPI1 EPB42 EPB42 NF1 NF1 F2RL1 F2RL1 TFRC TFRC ACIN1 ACIN1 CEBPE CEBPE BPGM BPGM CD81 CD81 CAMK4 CAMK4 EPHA2 EPHA2 NRROS NRROS SFXN1 SFXN1 EP300 EP300 ADGRF5 ADGRF5 NKAP NKAP NCKAP1L NCKAP1L PDE1B PDE1B UBD UBD SLC11A2 SLC11A2 OSTM1 OSTM1 NBEAL2 NBEAL2 G3R141_GORGO G3R141_GORGO ITGB6 ITGB6 NCOA6 NCOA6 ANXA2 ANXA2 G3R3B7_GORGO G3R3B7_GORGO TSPAN2 TSPAN2 JAGN1 JAGN1 SIRT1 SIRT1 G3R4E1_GORGO G3R4E1_GORGO TF TF G3R560_GORGO G3R560_GORGO SLC4A1 SLC4A1 LTBR LTBR TNFSF11 TNFSF11 SBNO2 SBNO2 G3R740_GORGO G3R740_GORGO G3R7N7_GORGO G3R7N7_GORGO FASN FASN TSPO2 TSPO2 G3R9L0_GORGO G3R9L0_GORGO DYRK3 DYRK3 LYN LYN IL17C IL17C G3RAB0_GORGO G3RAB0_GORGO GP9 GP9 GAB4 GAB4 LYAR LYAR RHEX RHEX IL20 IL20 KCNQ1 KCNQ1 G3RCB2_GORGO G3RCB2_GORGO SLC25A38 SLC25A38 MMP9 MMP9 KAT8 KAT8 AHSP AHSP PKNOX1 PKNOX1 UFL1 UFL1 SNRK SNRK PTPN6 PTPN6 HSPA9 HSPA9 SLC25A5 SLC25A5 G3REL7_GORGO G3REL7_GORGO ZFP36 ZFP36 PDE2A PDE2A SOCS1 SOCS1 BMP4 BMP4 TREM2 TREM2 LBR LBR RPS19 RPS19 KIT KIT IREB2 IREB2 BAP1 BAP1 CITED2 CITED2 CSF1 CSF1 EIF2AK1 EIF2AK1 CCR7 CCR7 TRIM10 TRIM10 G3RJZ9_GORGO G3RJZ9_GORGO HCLS1 HCLS1 TGFBR2 TGFBR2 TMEM14C TMEM14C ALAS1 ALAS1 G3RMA5_GORGO G3RMA5_GORGO CSF1R CSF1R TET2 TET2 G3RPA0_GORGO G3RPA0_GORGO G3RPM5_GORGO G3RPM5_GORGO IKZF1 IKZF1 G3RPR5_GORGO G3RPR5_GORGO WASF2 WASF2 G3RQ61_GORGO G3RQ61_GORGO MT1G MT1G IAPP IAPP SRC SRC G3RRC5_GORGO G3RRC5_GORGO G3RRP1_GORGO G3RRP1_GORGO GATA1 GATA1 G3RS82_GORGO G3RS82_GORGO BATF2 BATF2 TIRAP TIRAP RELB RELB SMAD5 SMAD5 AP3B1 AP3B1 G3RVS4_GORGO G3RVS4_GORGO GLO1 GLO1 WDR1 WDR1 OCSTAMP OCSTAMP CASP3 CASP3 G3S176_GORGO G3S176_GORGO NKX2-3 NKX2-3 PLA2G10 PLA2G10 KITLG KITLG GPR68 GPR68 HOXB7 HOXB7 G3S6F8_GORGO G3S6F8_GORGO IRF8 IRF8 SNX10 SNX10 ABCB10 ABCB10 PTPN2 PTPN2 PTBP3 PTBP3 KAT6A KAT6A ENSGGOP00000024523 ENSGGOP00000024523 ADAR ADAR GP1BA GP1BA PARP1 PARP1 RHAG RHAG TGFB1 TGFB1 IL11 IL11 GP1BB GP1BB PRDX3 PRDX3 LIF LIF PTPN11 PTPN11 DMTN DMTN PIP4K2A PIP4K2A NCAPG2 NCAPG2 ENSGGOP00000030478 ENSGGOP00000030478 CALCR CALCR ENSGGOP00000031261 ENSGGOP00000031261 ENSGGOP00000031992 ENSGGOP00000031992 ENSGGOP00000032023 ENSGGOP00000032023 ENSGGOP00000032524 ENSGGOP00000032524 PPARG PPARG ENSGGOP00000032619 ENSGGOP00000032619 ENSGGOP00000032627 ENSGGOP00000032627 ARID4A ARID4A ENSGGOP00000033404 ENSGGOP00000033404 ENSGGOP00000033701 ENSGGOP00000033701 TAL1 TAL1 PABPC4L PABPC4L CDK5RAP3 CDK5RAP3 BCL6 BCL6 EPAS1 EPAS1 ENSGGOP00000034163 ENSGGOP00000034163 MEIS1 MEIS1 RUNX1 RUNX1 ENSGGOP00000034916 ENSGGOP00000034916 ENSGGOP00000035083 ENSGGOP00000035083 BATF3 BATF3 ENSGGOP00000035952 ENSGGOP00000035952 ENSGGOP00000036103 ENSGGOP00000036103 ENSGGOP00000036219 ENSGGOP00000036219 THOC5 THOC5 ENSGGOP00000037095 ENSGGOP00000037095 TMOD3 TMOD3 CEBPA CEBPA DHRS7B DHRS7B IL25 IL25 MYH9 MYH9 CDKN2B CDKN2B MITF MITF CCN4 CCN4 ENSGGOP00000040081 ENSGGOP00000040081 IL15 IL15 ENSGGOP00000041090 ENSGGOP00000041090 ENSGGOP00000041335 ENSGGOP00000041335 BRD1 BRD1 FAM20C FAM20C RPS14 RPS14 ENSGGOP00000041818 ENSGGOP00000041818 CIB1 CIB1 RBPJ RBPJ CDC42 CDC42 ENSGGOP00000044109 ENSGGOP00000044109 CEBPG CEBPG SP3 SP3 CEBPB CEBPB JUNB JUNB ENSGGOP00000045574 ENSGGOP00000045574 FLI1 FLI1 ENSGGOP00000046335 ENSGGOP00000046335 TNFRSF11A TNFRSF11A THRA THRA EPO EPO SRP54 SRP54 ENSGGOP00000047608 ENSGGOP00000047608 IRF4 IRF4 INHBA INHBA VPS33B VPS33B CTNNB1 CTNNB1 ENSGGOP00000048909 ENSGGOP00000048909 CBFB CBFB ENSGGOP00000049072 ENSGGOP00000049072 SFRP1 SFRP1 ZNF385A ZNF385A APP APP SH3PXD2A SH3PXD2A C15H15orf41 C15H15orf41 PIK3R1 PIK3R1 ACTN1 ACTN1 ERCC2 ERCC2 FAM210B FAM210B ENSGGOP00000051960 ENSGGOP00000051960
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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LRRK1Leucine rich repeat kinase 1. (2015 aa)
THPOThrombopoietin. (353 aa)
ZBTB16Zinc finger and BTB domain containing 16. (673 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
L3MBTL3L3MBTL histone methyl-lysine binding protein 3. (780 aa)
KMT2ELysine methyltransferase 2E. (1858 aa)
GPR183G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (361 aa)
G3QER8_GORGOProteinase 3; Belongs to the peptidase S1 family. (256 aa)
ATP5IF1ATP synthase inhibitory factor subunit 1. (106 aa)
TGFBR3Transforming growth factor beta receptor 3. (860 aa)
GAB3GRB2 associated binding protein 3. (587 aa)
CSF2Colony stimulating factor 2. (144 aa)
MYBMYB proto-oncogene, transcription factor. (761 aa)
DHRS2Dehydrogenase/reductase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (300 aa)
FLVCR1Feline leukemia virus subgroup C cellular receptor 1. (555 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (446 aa)
DCSTAMPDendrocyte expressed seven transmembrane protein. (470 aa)
ALAS25-aminolevulinate synthase. (587 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (376 aa)
BATFBasic leucine zipper ATF-like transcription factor. (125 aa)
EFNA2Ephrin RBD domain-containing protein; Belongs to the ephrin family. (241 aa)
RPS640S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (249 aa)
TESCTescalcin. (214 aa)
PIRPirin; Belongs to the pirin family. (290 aa)
MFHAS1Malignant fibrous histiocytoma amplified sequence 1. (1010 aa)
CCL19C-C motif chemokine. (98 aa)
G3QKG3_GORGOInterleukin 31 receptor A. (691 aa)
CD4CD4 molecule. (458 aa)
SH2B3SH2B adaptor protein 3. (567 aa)
DNASE2Deoxyribonuclease 2, lysosomal. (360 aa)
KLF1Kruppel like factor 1. (362 aa)
INHAInhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (366 aa)
G3QN25_GORGOPolyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (660 aa)
NOTCH2Notch receptor 2. (2373 aa)
HIPK2Homeodomain interacting protein kinase 2. (1196 aa)
CD109CD109 molecule. (1446 aa)
FLNAFilamin A. (2647 aa)
FARP2FERM, ARH/RhoGEF and pleckstrin domain protein 2. (1054 aa)
RASGRP4RAS guanyl releasing protein 4. (668 aa)
SLC25A40Solute carrier family 25 member 40; Belongs to the mitochondrial carrier (TC 2.A.29) family. (338 aa)
ZBTB46Zinc finger and BTB domain containing 46. (589 aa)
G3QQC9_GORGOGlucose-6-phosphate dehydrogenase. (561 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa)
CSF3Colony stimulating factor 3. (207 aa)
EVI2BEcotropic viral integration site 2B. (448 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (413 aa)
RCOR1REST corepressor 1. (417 aa)
VPS33AVPS33A core subunit of CORVET and HOPS complexes; Belongs to the STXBP/unc-18/SEC1 family. (596 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
G3QS37_GORGOMegakaryocyte and platelet inhibitory receptor G6b. (242 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (153 aa)
CLEC1BC-type lectin domain family 1 member B. (229 aa)
G3QSH5_GORGOTyrosine-protein kinase. (1124 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
G3QT76_GORGOTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
UBA5Ubiquitin like modifier activating enzyme 5. (404 aa)
IFI16Interferon gamma inducible protein 16. (785 aa)
GATA2GATA binding protein 2. (480 aa)
GATA3GATA binding protein 3. (444 aa)
CLEC5AC-type lectin domain containing 5A. (188 aa)
SPI1Spi-1 proto-oncogene. (271 aa)
EPB42Erythrocyte membrane protein band 4.2. (691 aa)
NF1Neurofibromin 1. (2811 aa)
F2RL1F2R like trypsin receptor 1. (397 aa)
TFRCTransferrin receptor. (760 aa)
ACIN1Apoptotic chromatin condensation inducer 1. (1302 aa)
CEBPECCAAT/enhancer-binding protein. (281 aa)
BPGMPhosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (259 aa)
CD81Tetraspanin. (260 aa)
CAMK4Calcium/calmodulin dependent protein kinase IV. (419 aa)
EPHA2EPH receptor A2. (876 aa)
NRROSNegative regulator of reactive oxygen species. (692 aa)
SFXN1Sidoreflexin. (322 aa)
EP300E1A binding protein p300. (2416 aa)
ADGRF5Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. (1346 aa)
NKAPNFKB activating protein. (416 aa)
NCKAP1LNCK associated protein 1 like. (1127 aa)
PDE1BPhosphodiesterase. (536 aa)
UBDUbiquitin D. (165 aa)
SLC11A2Solute carrier family 11 member 2. (590 aa)
OSTM1Osteoclastogenesis associated transmembrane protein 1. (293 aa)
NBEAL2Neurobeachin like 2. (2754 aa)
G3R141_GORGOUncharacterized protein. (450 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (788 aa)
NCOA6Nuclear receptor coactivator 6. (2040 aa)
ANXA2Annexin. (357 aa)
G3R3B7_GORGOETS variant 2. (370 aa)
TSPAN2Tetraspanin. (243 aa)
JAGN1Jagunal homolog 1. (183 aa)
SIRT1Sirtuin 1. (751 aa)
G3R4E1_GORGOForkhead box P1. (693 aa)
TFTransferrin; Belongs to the transferrin family. (698 aa)
G3R560_GORGOLymphoid enhancer binding factor 1. (399 aa)
SLC4A1Anion exchange protein. (921 aa)
LTBRLymphotoxin beta receptor. (435 aa)
TNFSF11Tumor necrosis factor ligand superfamily member. (317 aa)
SBNO2Strawberry notch homolog 2. (1319 aa)
G3R740_GORGOBZIP domain-containing protein; Belongs to the bZIP family. (311 aa)
G3R7N7_GORGOAbl interactor 1. (508 aa)
FASNFatty acid synthase. (2500 aa)
TSPO2Translocator protein 2. (170 aa)
G3R9L0_GORGOPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family. (1072 aa)
DYRK3Dual specificity tyrosine phosphorylation regulated kinase 3. (588 aa)
LYNTyrosine-protein kinase. (512 aa)
IL17CInterleukin 17C. (197 aa)
G3RAB0_GORGOCBFA2/RUNX1 partner transcriptional co-repressor 3. (653 aa)
GP9Glycoprotein IX platelet. (177 aa)
GAB4GRB2 associated binding protein family member 4. (575 aa)
LYARLy1 antibody reactive. (379 aa)
RHEXRegulator of hemoglobinization and erythroid cell expansion. (172 aa)
IL20Interleukin 20. (176 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (676 aa)
G3RCB2_GORGOATPase H+ transporting accessory protein 1. (446 aa)
SLC25A38Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis. Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily. (304 aa)
MMP9Matrix metallopeptidase 9. (707 aa)
KAT8Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (467 aa)
AHSPAlpha hemoglobin stabilizing protein. (102 aa)
PKNOX1PBX/knotted 1 homeobox 1. (436 aa)
UFL1UFM1 specific ligase 1. (794 aa)
SNRKSNF related kinase. (765 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
HSPA9Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family. (679 aa)
SLC25A5Solute carrier family 25 member 5; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
G3REL7_GORGOJumonji domain containing 6, arginine demethylase and lysine hydroxylase. (420 aa)
ZFP36ZFP36 ring finger protein. (332 aa)
PDE2APhosphodiesterase. (941 aa)
SOCS1Suppressor of cytokine signaling 1. (211 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (230 aa)
LBRLamin B receptor. (615 aa)
RPS19Ribosomal protein S19. (145 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (976 aa)
IREB2Iron responsive element binding protein 2; Belongs to the aconitase/IPM isomerase family. (963 aa)
BAP1Ubiquitin carboxyl-terminal hydrolase. (729 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (554 aa)
EIF2AK1Eukaryotic translation initiation factor 2 alpha kinase 1. (630 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa)
TRIM10Tripartite motif containing 10. (481 aa)
G3RJZ9_GORGORB transcriptional corepressor 1. (756 aa)
HCLS1Hematopoietic cell-specific Lyn substrate 1. (484 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
TMEM14CTransmembrane protein 14C. (100 aa)
ALAS15-aminolevulinate synthase. (640 aa)
G3RMA5_GORGOTyrosine-protein phosphatase non-receptor type. (415 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa)
TET2Tet methylcytosine dioxygenase 2. (2023 aa)
G3RPA0_GORGO40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (204 aa)
G3RPM5_GORGOPromyelocytic leukemia. (834 aa)
IKZF1IKAROS family zinc finger 1. (519 aa)
G3RPR5_GORGOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (193 aa)
WASF2WASP family member 2. (498 aa)
G3RQ61_GORGOIntegrin beta; Belongs to the integrin beta chain family. (694 aa)
MT1GMetallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (61 aa)
IAPPIslet amyloid polypeptide. (89 aa)
SRCTyrosine-protein kinase. (542 aa)
G3RRC5_GORGOUncharacterized protein. (491 aa)
G3RRP1_GORGOUncharacterized protein. (270 aa)
GATA1GATA binding protein 1. (413 aa)
G3RS82_GORGOUncharacterized protein. (713 aa)
BATF2Basic leucine zipper ATF-like transcription factor 2. (274 aa)
TIRAPTIR domain containing adaptor protein. (221 aa)
RELBRELB proto-oncogene, NF-kB subunit. (579 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
AP3B1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1094 aa)
G3RVS4_GORGOSignal transducer and activator of transcription. (787 aa)
GLO1Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (184 aa)
WDR1WD repeat domain 1. (606 aa)
OCSTAMPOsteoclast stimulatory transmembrane protein. (565 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (277 aa)
G3S176_GORGOMADS-box domain-containing protein. (473 aa)
NKX2-3NK2 homeobox 3. (361 aa)
PLA2G10Phospholipase A(2). (155 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa)
GPR68G protein-coupled receptor 68; Belongs to the G-protein coupled receptor 1 family. (375 aa)
HOXB7Homeobox protein Hox-B7; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Antp homeobox family. (217 aa)
G3S6F8_GORGOMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1514 aa)
IRF8Interferon regulatory factor 8. (426 aa)
SNX10Sorting nexin 10. (201 aa)
ABCB10ATP binding cassette subfamily B member 10. (738 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (387 aa)
PTBP3Polypyrimidine tract binding protein 3. (558 aa)
KAT6AHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2005 aa)
ENSGGOP00000024523annotation not available (408 aa)
ADARAdenosine deaminase RNA specific. (1229 aa)
GP1BAGlycoprotein Ib platelet subunit alpha. (654 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
RHAGAmmonium transporter Rh type A; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. (409 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
IL11Interleukin 11. (199 aa)
GP1BBGlycoprotein Ib platelet subunit beta. (206 aa)
PRDX3Peroxiredoxin 3. (256 aa)
LIFLIF interleukin 6 family cytokine. (202 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
DMTNDematin actin binding protein. (405 aa)
PIP4K2APhosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (396 aa)
NCAPG2Non-SMC condensin II complex subunit G2. (1156 aa)
ENSGGOP00000030478Tyrosine-protein kinase. (1151 aa)
CALCRCalcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (509 aa)
ENSGGOP00000031261Myocyte enhancer factor 2C. (483 aa)
ENSGGOP00000031992Uncharacterized protein. (76 aa)
ENSGGOP00000032023Macrophage erythroblast attacher. (434 aa)
ENSGGOP00000032524Annexin. (318 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
ENSGGOP00000032619cAMP responsive element binding protein 1. (341 aa)
ENSGGOP00000032627Uncharacterized protein. (118 aa)
ARID4AAT-rich interaction domain 4A. (1259 aa)
ENSGGOP00000033404Caspase 8; Belongs to the peptidase C14A family. (496 aa)
ENSGGOP00000033701Uncharacterized protein. (503 aa)
TAL1TAL bHLH transcription factor 1, erythroid differentiation factor. (331 aa)
PABPC4LPoly(A) binding protein cytoplasmic 4 like. (370 aa)
CDK5RAP3CDK5 regulatory subunit associated protein 3. (531 aa)
BCL6BCL6 transcription repressor. (706 aa)
EPAS1Uncharacterized protein. (574 aa)
ENSGGOP00000034163Uncharacterized protein. (485 aa)
MEIS1Homeobox domain-containing protein. (463 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa)
ENSGGOP00000034916PABC domain-containing protein. (209 aa)
ENSGGOP00000035083DUF1279 domain-containing protein. (216 aa)
BATF3Basic leucine zipper ATF-like transcription factor 3. (120 aa)
ENSGGOP00000035952TNF receptor-associated factor. (485 aa)
ENSGGOP00000036103Uncharacterized protein. (509 aa)
ENSGGOP00000036219annotation not available (193 aa)
THOC5THO complex 5. (683 aa)
ENSGGOP00000037095Uncharacterized protein. (575 aa)
TMOD3Tropomodulin 3. (352 aa)
CEBPABZIP domain-containing protein. (141 aa)
DHRS7BDehydrogenase/reductase 7B; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (326 aa)
IL25Interleukin 25. (177 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1894 aa)
CDKN2BCyclin dependent kinase inhibitor 2B. (138 aa)
MITFMelanocyte inducing transcription factor. (526 aa)
CCN4Cellular communication network factor 4. (368 aa)
ENSGGOP00000040081Uncharacterized protein. (121 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
ENSGGOP0000004109040S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (243 aa)
ENSGGOP00000041335Uncharacterized protein. (158 aa)
BRD1EPL1 domain-containing protein. (276 aa)
FAM20CFam20C domain-containing protein. (296 aa)
RPS14Ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family. (155 aa)
ENSGGOP00000041818Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (446 aa)
CIB1Calcium and integrin binding 1. (235 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (488 aa)
CDC42Cell division cycle 42. (191 aa)
ENSGGOP00000044109Uncharacterized protein; Belongs to the universal ribosomal protein uS11 family. (179 aa)
CEBPGCCAAT enhancer binding protein gamma. (150 aa)
SP3Sp3 transcription factor. (722 aa)
CEBPBCCAAT/enhancer-binding protein. (345 aa)
JUNBJunB proto-oncogene, AP-1 transcription factor subunit. (347 aa)
ENSGGOP00000045574Uncharacterized protein. (316 aa)
FLI1Fli-1 proto-oncogene, ETS transcription factor. (452 aa)
ENSGGOP00000046335Uncharacterized protein. (118 aa)
TNFRSF11ATNF receptor superfamily member 11a. (616 aa)
THRAUncharacterized protein. (595 aa)
EPOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (193 aa)
SRP54Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (504 aa)
ENSGGOP00000047608Uncharacterized protein; Belongs to the universal ribosomal protein uS11 family. (150 aa)
IRF4Interferon regulatory factor 4. (451 aa)
INHBAInhibin subunit beta A. (426 aa)
VPS33BUncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (617 aa)
CTNNB1Catenin beta 1. (781 aa)
ENSGGOP00000048909Uncharacterized protein. (81 aa)
CBFBCore-binding factor subunit beta. (182 aa)
ENSGGOP00000049072Protein kinase domain-containing protein. (296 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
ZNF385AZinc finger protein 385A. (465 aa)
APPAmyloid beta precursor protein. (771 aa)
SH3PXD2ASH3 and PX domains 2A. (1133 aa)
C15H15orf41Chromosome 15 open reading frame 41. (281 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (723 aa)
ACTN1Actinin alpha 1. (914 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (810 aa)
FAM210BFamily with sequence similarity 210 member B. (192 aa)
ENSGGOP00000051960Annexin. (330 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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