STRINGSTRING
L3MBTL3 L3MBTL3 KMT2E KMT2E ATP5IF1 ATP5IF1 TGFBR3 TGFBR3 MYB MYB FLVCR1 FLVCR1 ALAS2 ALAS2 RPS6 RPS6 MFHAS1 MFHAS1 SH2B3 SH2B3 DNASE2 DNASE2 KLF1 KLF1 INHA INHA HIPK2 HIPK2 SLC25A40 SLC25A40 G3QQC9_GORGO G3QQC9_GORGO RCOR1 RCOR1 G3QS37_GORGO G3QS37_GORGO G3QSH5_GORGO G3QSH5_GORGO UBA5 UBA5 GATA3 GATA3 SPI1 SPI1 EPB42 EPB42 ACIN1 ACIN1 BPGM BPGM SFXN1 SFXN1 ADGRF5 ADGRF5 NCKAP1L NCKAP1L SLC11A2 SLC11A2 G3R141_GORGO G3R141_GORGO G3R3B7_GORGO G3R3B7_GORGO SLC4A1 SLC4A1 TSPO2 TSPO2 DYRK3 DYRK3 LYN LYN LYAR LYAR RHEX RHEX KCNQ1 KCNQ1 SLC25A38 SLC25A38 AHSP AHSP PKNOX1 PKNOX1 UFL1 UFL1 HSPA9 HSPA9 SLC25A5 SLC25A5 G3REL7_GORGO G3REL7_GORGO BMP4 BMP4 RPS19 RPS19 KIT KIT BAP1 BAP1 CITED2 CITED2 TRIM10 TRIM10 G3RJZ9_GORGO G3RJZ9_GORGO HCLS1 HCLS1 TMEM14C TMEM14C ALAS1 ALAS1 G3RMA5_GORGO G3RMA5_GORGO G3RPA0_GORGO G3RPA0_GORGO IKZF1 IKZF1 G3RPR5_GORGO G3RPR5_GORGO GATA1 GATA1 G3RS82_GORGO G3RS82_GORGO SMAD5 SMAD5 G3RVS4_GORGO G3RVS4_GORGO CASP3 CASP3 G3S176_GORGO G3S176_GORGO PLA2G10 PLA2G10 G3S6F8_GORGO G3S6F8_GORGO ABCB10 ABCB10 PTPN2 PTPN2 PTBP3 PTBP3 ENSGGOP00000024523 ENSGGOP00000024523 ADAR ADAR RHAG RHAG DMTN DMTN NCAPG2 NCAPG2 ENSGGOP00000030478 ENSGGOP00000030478 ENSGGOP00000031992 ENSGGOP00000031992 ENSGGOP00000032023 ENSGGOP00000032023 ENSGGOP00000032627 ENSGGOP00000032627 ARID4A ARID4A ENSGGOP00000033701 ENSGGOP00000033701 TAL1 TAL1 CDK5RAP3 CDK5RAP3 BCL6 BCL6 EPAS1 EPAS1 ENSGGOP00000035083 ENSGGOP00000035083 ENSGGOP00000036219 ENSGGOP00000036219 TMOD3 TMOD3 ENSGGOP00000040081 ENSGGOP00000040081 ENSGGOP00000041090 ENSGGOP00000041090 ENSGGOP00000041335 ENSGGOP00000041335 BRD1 BRD1 RPS14 RPS14 ENSGGOP00000041818 ENSGGOP00000041818 ENSGGOP00000044109 ENSGGOP00000044109 CEBPG CEBPG SP3 SP3 ENSGGOP00000046335 ENSGGOP00000046335 THRA THRA EPO EPO ENSGGOP00000047608 ENSGGOP00000047608 INHBA INHBA ENSGGOP00000048909 ENSGGOP00000048909 C15H15orf41 C15H15orf41 ERCC2 ERCC2 FAM210B FAM210B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
L3MBTL3L3MBTL histone methyl-lysine binding protein 3. (780 aa)
KMT2ELysine methyltransferase 2E. (1858 aa)
ATP5IF1ATP synthase inhibitory factor subunit 1. (106 aa)
TGFBR3Transforming growth factor beta receptor 3. (860 aa)
MYBMYB proto-oncogene, transcription factor. (761 aa)
FLVCR1Feline leukemia virus subgroup C cellular receptor 1. (555 aa)
ALAS25-aminolevulinate synthase. (587 aa)
RPS640S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (249 aa)
MFHAS1Malignant fibrous histiocytoma amplified sequence 1. (1010 aa)
SH2B3SH2B adaptor protein 3. (567 aa)
DNASE2Deoxyribonuclease 2, lysosomal. (360 aa)
KLF1Kruppel like factor 1. (362 aa)
INHAInhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (366 aa)
HIPK2Homeodomain interacting protein kinase 2. (1196 aa)
SLC25A40Solute carrier family 25 member 40; Belongs to the mitochondrial carrier (TC 2.A.29) family. (338 aa)
G3QQC9_GORGOGlucose-6-phosphate dehydrogenase. (561 aa)
RCOR1REST corepressor 1. (417 aa)
G3QS37_GORGOMegakaryocyte and platelet inhibitory receptor G6b. (242 aa)
G3QSH5_GORGOTyrosine-protein kinase. (1124 aa)
UBA5Ubiquitin like modifier activating enzyme 5. (404 aa)
GATA3GATA binding protein 3. (444 aa)
SPI1Spi-1 proto-oncogene. (271 aa)
EPB42Erythrocyte membrane protein band 4.2. (691 aa)
ACIN1Apoptotic chromatin condensation inducer 1. (1302 aa)
BPGMPhosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (259 aa)
SFXN1Sidoreflexin. (322 aa)
ADGRF5Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. (1346 aa)
NCKAP1LNCK associated protein 1 like. (1127 aa)
SLC11A2Solute carrier family 11 member 2. (590 aa)
G3R141_GORGOUncharacterized protein. (450 aa)
G3R3B7_GORGOETS variant 2. (370 aa)
SLC4A1Anion exchange protein. (921 aa)
TSPO2Translocator protein 2. (170 aa)
DYRK3Dual specificity tyrosine phosphorylation regulated kinase 3. (588 aa)
LYNTyrosine-protein kinase. (512 aa)
LYARLy1 antibody reactive. (379 aa)
RHEXRegulator of hemoglobinization and erythroid cell expansion. (172 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (676 aa)
SLC25A38Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis. Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily. (304 aa)
AHSPAlpha hemoglobin stabilizing protein. (102 aa)
PKNOX1PBX/knotted 1 homeobox 1. (436 aa)
UFL1UFM1 specific ligase 1. (794 aa)
HSPA9Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family. (679 aa)
SLC25A5Solute carrier family 25 member 5; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
G3REL7_GORGOJumonji domain containing 6, arginine demethylase and lysine hydroxylase. (420 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
RPS19Ribosomal protein S19. (145 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (976 aa)
BAP1Ubiquitin carboxyl-terminal hydrolase. (729 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa)
TRIM10Tripartite motif containing 10. (481 aa)
G3RJZ9_GORGORB transcriptional corepressor 1. (756 aa)
HCLS1Hematopoietic cell-specific Lyn substrate 1. (484 aa)
TMEM14CTransmembrane protein 14C. (100 aa)
ALAS15-aminolevulinate synthase. (640 aa)
G3RMA5_GORGOTyrosine-protein phosphatase non-receptor type. (415 aa)
G3RPA0_GORGO40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (204 aa)
IKZF1IKAROS family zinc finger 1. (519 aa)
G3RPR5_GORGOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (193 aa)
GATA1GATA binding protein 1. (413 aa)
G3RS82_GORGOUncharacterized protein. (713 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
G3RVS4_GORGOSignal transducer and activator of transcription. (787 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (277 aa)
G3S176_GORGOMADS-box domain-containing protein. (473 aa)
PLA2G10Phospholipase A(2). (155 aa)
G3S6F8_GORGOMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1514 aa)
ABCB10ATP binding cassette subfamily B member 10. (738 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (387 aa)
PTBP3Polypyrimidine tract binding protein 3. (558 aa)
ENSGGOP00000024523annotation not available (408 aa)
ADARAdenosine deaminase RNA specific. (1229 aa)
RHAGAmmonium transporter Rh type A; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. (409 aa)
DMTNDematin actin binding protein. (405 aa)
NCAPG2Non-SMC condensin II complex subunit G2. (1156 aa)
ENSGGOP00000030478Tyrosine-protein kinase. (1151 aa)
ENSGGOP00000031992Uncharacterized protein. (76 aa)
ENSGGOP00000032023Macrophage erythroblast attacher. (434 aa)
ENSGGOP00000032627Uncharacterized protein. (118 aa)
ARID4AAT-rich interaction domain 4A. (1259 aa)
ENSGGOP00000033701Uncharacterized protein. (503 aa)
TAL1TAL bHLH transcription factor 1, erythroid differentiation factor. (331 aa)
CDK5RAP3CDK5 regulatory subunit associated protein 3. (531 aa)
BCL6BCL6 transcription repressor. (706 aa)
EPAS1Uncharacterized protein. (574 aa)
ENSGGOP00000035083DUF1279 domain-containing protein. (216 aa)
ENSGGOP00000036219annotation not available (193 aa)
TMOD3Tropomodulin 3. (352 aa)
ENSGGOP00000040081Uncharacterized protein. (121 aa)
ENSGGOP0000004109040S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (243 aa)
ENSGGOP00000041335Uncharacterized protein. (158 aa)
BRD1EPL1 domain-containing protein. (276 aa)
RPS14Ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family. (155 aa)
ENSGGOP00000041818Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (446 aa)
ENSGGOP00000044109Uncharacterized protein; Belongs to the universal ribosomal protein uS11 family. (179 aa)
CEBPGCCAAT enhancer binding protein gamma. (150 aa)
SP3Sp3 transcription factor. (722 aa)
ENSGGOP00000046335Uncharacterized protein. (118 aa)
THRAUncharacterized protein. (595 aa)
EPOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (193 aa)
ENSGGOP00000047608Uncharacterized protein; Belongs to the universal ribosomal protein uS11 family. (150 aa)
INHBAInhibin subunit beta A. (426 aa)
ENSGGOP00000048909Uncharacterized protein. (81 aa)
C15H15orf41Chromosome 15 open reading frame 41. (281 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (810 aa)
FAM210BFamily with sequence similarity 210 member B. (192 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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