(21 nodes) Platelet formation network (Gorilla gorilla)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	VPS33A	VPS33A core subunit of CORVET and HOPS complexes; Belongs to the STXBP/unc-18/SEC1 family. (596 aa)
	G3QS37_GORGO	Megakaryocyte and platelet inhibitory receptor G6b. (242 aa)
	CLEC1B	C-type lectin domain family 1 member B. (229 aa)
	EP300	E1A binding protein p300. (2416 aa)
	NBEAL2	Neurobeachin like 2. (2754 aa)
	PTPN6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
	G3RRP1_GORGO	Uncharacterized protein. (270 aa)
	GATA1	GATA binding protein 1. (413 aa)
	WDR1	WD repeat domain 1. (606 aa)
	G3S176_GORGO	MADS-box domain-containing protein. (473 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
	ENSGGOP00000031261	Myocyte enhancer factor 2C. (483 aa)
	ENSGGOP00000034163	Uncharacterized protein. (485 aa)
	ENSGGOP00000036103	Uncharacterized protein. (509 aa)
	ENSGGOP00000037095	Uncharacterized protein. (575 aa)
	MYH9	Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1894 aa)
	ENSGGOP00000041335	Uncharacterized protein. (158 aa)
	CIB1	Calcium and integrin binding 1. (235 aa)
	ZNF385A	Zinc finger protein 385A. (465 aa)
	ACTN1	Actinin alpha 1. (914 aa)
	CASP9	Caspase 9; Belongs to the peptidase C14A family. (446 aa)

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTN1	MYH9	ENSGGOP00000050636	ENSGGOP00000038991	Actinin alpha 1.	Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.658
ACTN1	WDR1	ENSGGOP00000050636	ENSGGOP00000020790	Actinin alpha 1.	WD repeat domain 1.	0.485
CLEC1B	G3QS37_GORGO	ENSGGOP00000005579	ENSGGOP00000005461	C-type lectin domain family 1 member B.	Megakaryocyte and platelet inhibitory receptor G6b.	0.574
CLEC1B	PTPN6	ENSGGOP00000005579	ENSGGOP00000013813	C-type lectin domain family 1 member B.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.417
ENSGGOP00000031261	EP300	ENSGGOP00000031261	ENSGGOP00000008032	Myocyte enhancer factor 2C.	E1A binding protein p300.	0.713
ENSGGOP00000031261	G3S176_GORGO	ENSGGOP00000031261	ENSGGOP00000021821	Myocyte enhancer factor 2C.	MADS-box domain-containing protein.	0.424
ENSGGOP00000034163	G3QS37_GORGO	ENSGGOP00000034163	ENSGGOP00000005461	Uncharacterized protein.	Megakaryocyte and platelet inhibitory receptor G6b.	0.809
ENSGGOP00000034163	PTPN6	ENSGGOP00000034163	ENSGGOP00000013813	Uncharacterized protein.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.527
ENSGGOP00000036103	G3QS37_GORGO	ENSGGOP00000036103	ENSGGOP00000005461	Uncharacterized protein.	Megakaryocyte and platelet inhibitory receptor G6b.	0.689
ENSGGOP00000036103	PTPN6	ENSGGOP00000036103	ENSGGOP00000013813	Uncharacterized protein.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.484
ENSGGOP00000037095	G3QS37_GORGO	ENSGGOP00000037095	ENSGGOP00000005461	Uncharacterized protein.	Megakaryocyte and platelet inhibitory receptor G6b.	0.689
ENSGGOP00000037095	PTPN6	ENSGGOP00000037095	ENSGGOP00000013813	Uncharacterized protein.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.478
ENSGGOP00000041335	EP300	ENSGGOP00000041335	ENSGGOP00000008032	Uncharacterized protein.	E1A binding protein p300.	0.474
ENSGGOP00000041335	GATA1	ENSGGOP00000041335	ENSGGOP00000018626	Uncharacterized protein.	GATA binding protein 1.	0.863
EP300	ENSGGOP00000031261	ENSGGOP00000008032	ENSGGOP00000031261	E1A binding protein p300.	Myocyte enhancer factor 2C.	0.713
EP300	ENSGGOP00000041335	ENSGGOP00000008032	ENSGGOP00000041335	E1A binding protein p300.	Uncharacterized protein.	0.474
EP300	GATA1	ENSGGOP00000008032	ENSGGOP00000018626	E1A binding protein p300.	GATA binding protein 1.	0.870
G3QS37_GORGO	CLEC1B	ENSGGOP00000005461	ENSGGOP00000005579	Megakaryocyte and platelet inhibitory receptor G6b.	C-type lectin domain family 1 member B.	0.574
G3QS37_GORGO	ENSGGOP00000034163	ENSGGOP00000005461	ENSGGOP00000034163	Megakaryocyte and platelet inhibitory receptor G6b.	Uncharacterized protein.	0.809
G3QS37_GORGO	ENSGGOP00000036103	ENSGGOP00000005461	ENSGGOP00000036103	Megakaryocyte and platelet inhibitory receptor G6b.	Uncharacterized protein.	0.689