STRINGSTRING
CSF2 CSF2 PIR PIR G3QKG3_GORGO G3QKG3_GORGO IFI16 IFI16 PDE1B PDE1B FASN FASN PDE2A PDE2A BMP4 BMP4 CSF1 CSF1 CSF1R CSF1R MT1G MT1G G3RS82_GORGO G3RS82_GORGO GPR68 GPR68 G3S6F8_GORGO G3S6F8_GORGO ENSGGOP00000024523 ENSGGOP00000024523 PPARG PPARG THOC5 THOC5 MYH9 MYH9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CSF2Colony stimulating factor 2. (144 aa)
PIRPirin; Belongs to the pirin family. (290 aa)
G3QKG3_GORGOInterleukin 31 receptor A. (691 aa)
IFI16Interferon gamma inducible protein 16. (785 aa)
PDE1BPhosphodiesterase. (536 aa)
FASNFatty acid synthase. (2500 aa)
PDE2APhosphodiesterase. (941 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (554 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa)
MT1GMetallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (61 aa)
G3RS82_GORGOUncharacterized protein. (713 aa)
GPR68G protein-coupled receptor 68; Belongs to the G-protein coupled receptor 1 family. (375 aa)
G3S6F8_GORGOMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1514 aa)
ENSGGOP00000024523annotation not available (408 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
THOC5THO complex 5. (683 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1894 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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