STRINGSTRING
SERP1 SERP1 AMFR AMFR TBL2 TBL2 DNAJC10 DNAJC10 QRICH1 QRICH1 OS9 OS9 XBP1 XBP1 ATF6B ATF6B CDK5RAP3 CDK5RAP3 ENSGGOP00000033934 ENSGGOP00000033934 ENSGGOP00000033701 ENSGGOP00000033701 NFE2L2 NFE2L2 ENSGGOP00000033459 ENSGGOP00000033459 CCND1 CCND1 ENSGGOP00000032856 ENSGGOP00000032856 DERL2 DERL2 ENSGGOP00000032650 ENSGGOP00000032650 ENSGGOP00000032087 ENSGGOP00000032087 SELENOS SELENOS TMED2 TMED2 PARP16 PARP16 HSPA5 HSPA5 G3RZZ0_GORGO G3RZZ0_GORGO ERO1A ERO1A EIF2AK2 EIF2AK2 G3RT49_GORGO G3RT49_GORGO G3RPU5_GORGO G3RPU5_GORGO RHBDD2 RHBDD2 CTH CTH SERP2 SERP2 CREB3L1 CREB3L1 ATF3 ATF3 ATF6 ATF6 STC2 STC2 ERN2 ERN2 G3R8R1_GORGO G3R8R1_GORGO MBTPS2 MBTPS2 EIF2AK3 EIF2AK3 HERPUD2 HERPUD2 MBTPS1 MBTPS1 ATF4 ATF4 DERL1 DERL1 EP300 EP300 VAPB VAPB CREB3 CREB3 PTPN1 PTPN1 CREBZF CREBZF ERN1 ERN1 YOD1 YOD1 CREB3L4 CREB3L4 HERPUD1 HERPUD1 CREB3L2 CREB3L2 WFS1 WFS1 VCP VCP DDIT3 DDIT3 ERMP1 ERMP1 EIF2S1 EIF2S1 FGF21 FGF21 DERL3 DERL3 ERLEC1 ERLEC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SERP1Stress-associated endoplasmic reticulum protein; May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation. Belongs to the RAMP4 family. (66 aa)
AMFRAutocrine motility factor receptor. (639 aa)
TBL2Transducin beta like 2. (434 aa)
DNAJC10DnaJ heat shock protein family (Hsp40) member C10. (810 aa)
QRICH1Glutamine rich 1. (779 aa)
OS9OS9 endoplasmic reticulum lectin. (730 aa)
XBP1BZIP domain-containing protein. (380 aa)
ATF6BActivating transcription factor 6 beta. (703 aa)
CDK5RAP3CDK5 regulatory subunit associated protein 3. (531 aa)
ENSGGOP00000033934Uncharacterized protein. (318 aa)
ENSGGOP00000033701Uncharacterized protein. (503 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (600 aa)
ENSGGOP00000033459BZIP domain-containing protein. (350 aa)
CCND1Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (295 aa)
ENSGGOP00000032856Transmembrane O-mannosyltransferase targeting cadherins 4. (760 aa)
DERL2Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (239 aa)
ENSGGOP00000032650STIP1 homology and U-box containing protein 1. (303 aa)
ENSGGOP00000032087BZIP domain-containing protein. (342 aa)
SELENOSUncharacterized protein. (218 aa)
TMED2Transmembrane p24 trafficking protein 2. (208 aa)
PARP16Poly [ADP-ribose] polymerase. (323 aa)
HSPA5Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa)
G3RZZ0_GORGOCyclin N-terminal domain-containing protein; Belongs to the cyclin family. (294 aa)
ERO1AEndoplasmic reticulum oxidoreductase 1 alpha. (468 aa)
EIF2AK2Eukaryotic translation initiation factor 2 alpha kinase 2. (551 aa)
G3RT49_GORGOcAMP responsive element binding protein 3 like 3. (461 aa)
G3RPU5_GORGOUncharacterized protein; Belongs to the heat shock protein 70 family. (613 aa)
RHBDD2Rhomboid domain containing 2. (409 aa)
CTHCystathionine gamma-lyase. (405 aa)
SERP2Stress-associated endoplasmic reticulum protein; May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation. Belongs to the RAMP4 family. (65 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (519 aa)
ATF3Activating transcription factor 3. (181 aa)
ATF6Activating transcription factor 6. (670 aa)
STC2Stanniocalcin 2. (302 aa)
ERN2Endoplasmic reticulum to nucleus signaling 2. (926 aa)
G3R8R1_GORGOCaspase 12 (gene/pseudogene); Belongs to the peptidase C14A family. (341 aa)
MBTPS2Membrane bound transcription factor peptidase, site 2. (520 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1116 aa)
HERPUD2HERPUD family member 2. (406 aa)
MBTPS1Membrane bound transcription factor peptidase, site 1. (1052 aa)
ATF4Activating transcription factor 4. (351 aa)
DERL1Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (251 aa)
EP300E1A binding protein p300. (2416 aa)
VAPBVAMP associated protein B and C. (243 aa)
CREB3cAMP responsive element binding protein 3. (371 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (435 aa)
CREBZFCREB/ATF bZIP transcription factor. (358 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1. (977 aa)
YOD1YOD1 deubiquitinase. (348 aa)
CREB3L4cAMP responsive element binding protein 3 like 4. (395 aa)
HERPUD1Homocysteine inducible ER protein with ubiquitin like domain 1. (391 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (520 aa)
WFS1Wolframin ER transmembrane glycoprotein. (890 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (806 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa)
ERMP1Endoplasmic reticulum metallopeptidase 1. (904 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit alpha. (315 aa)
FGF21Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
DERL3Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (235 aa)
ERLEC1Endoplasmic reticulum lectin 1. (483 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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