STRINGSTRING
FCN3 FCN3 STAP1 STAP1 EMILIN2 EMILIN2 TRIM56 TRIM56 TTBK1 TTBK1 CX3CL1 CX3CL1 LRSAM1 LRSAM1 S100A9 S100A9 KLK5 KLK5 C2CD4C C2CD4C MASP1 MASP1 ITGA2 ITGA2 ADORA2B ADORA2B IL23A IL23A GBP5 GBP5 CTSC CTSC GPSM3 GPSM3 AKIRIN2 AKIRIN2 GRP GRP PGC PGC NLRC4 NLRC4 ETS1 ETS1 LAMP1 LAMP1 TLR2 TLR2 PAK1 PAK1 LAG3 LAG3 UBE2K UBE2K PSPC1 PSPC1 POMC POMC TOMM70 TOMM70 LGALS2 LGALS2 EREG EREG HPX HPX G3QN85_GORGO G3QN85_GORGO SUCNR1 SUCNR1 IL12B IL12B NPY5R NPY5R TRPV4 TRPV4 AP1G1 AP1G1 CCL24 CCL24 MGST2 MGST2 IL17F IL17F IL16 IL16 G3QRS4_GORGO G3QRS4_GORGO FPR2 FPR2 CLOCK CLOCK TNFSF18 TNFSF18 TRAF6 TRAF6 FFAR2 FFAR2 MNDA MNDA G3QT71_GORGO G3QT71_GORGO G3QT76_GORGO G3QT76_GORGO CREBBP CREBBP IFNG IFNG CD226 CD226 G3QTD2_GORGO G3QTD2_GORGO IFI16 IFI16 AIM2 AIM2 NONO NONO CCDC142 CCDC142 NECTIN2 NECTIN2 IL1B IL1B NPAS2 NPAS2 SPI1 SPI1 G3QUX8_GORGO G3QUX8_GORGO S100A12 S100A12 IKBKB IKBKB IL12A IL12A CLNK CLNK PLA2G5 PLA2G5 G3QVM2_GORGO G3QVM2_GORGO COLEC10 COLEC10 F2RL1 F2RL1 HYAL2 HYAL2 OSM OSM SERPINE1 SERPINE1 POLR3C POLR3C POLR3D POLR3D G3QWJ4_GORGO G3QWJ4_GORGO FABP4 FABP4 WNT5A WNT5A G3QX51_GORGO G3QX51_GORGO CD81 CD81 G3QXA0_GORGO G3QXA0_GORGO PTGER4 PTGER4 CD47 CD47 IL21 IL21 FYN FYN EP300 EP300 PLA2G2A PLA2G2A ZNFX1 ZNFX1 G3R037_GORGO G3R037_GORGO DDTL DDTL MMP8 MMP8 IFI35 IFI35 NLRP12 NLRP12 NLRP10 NLRP10 TXK TXK MMRN2 MMRN2 RAET1E RAET1E NFKBIA NFKBIA G3R212_GORGO G3R212_GORGO IL17A IL17A NLRC5 NLRC5 G3R3U7_GORGO G3R3U7_GORGO SYK SYK KLRD1 KLRD1 G3R570_GORGO G3R570_GORGO NOD2 NOD2 RIPK2 RIPK2 ZBP1 ZBP1 TNFSF11 TNFSF11 LGALS1 LGALS1 PQBP1 PQBP1 NLRP1 NLRP1 XRCC5 XRCC5 POLR3F POLR3F UCN UCN TRADD TRADD G3R8T5_GORGO G3R8T5_GORGO USP27X USP27X VAV1 VAV1 TLR8 TLR8 PYHIN1 PYHIN1 LYN LYN RIPK1 RIPK1 G3RAJ9_GORGO G3RAJ9_GORGO G3RAL4_GORGO G3RAL4_GORGO NMI NMI G3RD62_GORGO G3RD62_GORGO ALOX5AP ALOX5AP G3RE11_GORGO G3RE11_GORGO HEXIM1 HEXIM1 SLC15A4 SLC15A4 PDE2A PDE2A NKG7 NKG7 TREM2 TREM2 RPS19 RPS19 TYROBP TYROBP G3RI71_GORGO G3RI71_GORGO G3RID2_GORGO G3RID2_GORGO GRN GRN IL18 IL18 XRCC6 XRCC6 PARP9 PARP9 RNF31 RNF31 STING1 STING1 PENK PENK CCR7 CCR7 IL1RL1 IL1RL1 G3RKL3_GORGO G3RKL3_GORGO GRPR GRPR PYCARD PYCARD IFNB1 IFNB1 MMP12 MMP12 NINJ1 NINJ1 CCR2 CCR2 CRTAM CRTAM PTGS2 PTGS2 G3RQF4_GORGO G3RQF4_GORGO G3RR23_GORGO G3RR23_GORGO G3RR32_GORGO G3RR32_GORGO SRC SRC CCL1 CCL1 G3RRC5_GORGO G3RRC5_GORGO TNFSF4 TNFSF4 ARG1 ARG1 IL6 IL6 IRGM IRGM TIRAP TIRAP G3RT38_GORGO G3RT38_GORGO G3RT49_GORGO G3RT49_GORGO KLK3 KLK3 PLSCR1 PLSCR1 G3RUA1_GORGO G3RUA1_GORGO MASP2 MASP2 CXHXorf21 CXHXorf21 IKBKE IKBKE G3RVM4_GORGO G3RVM4_GORGO G3RVS4_GORGO G3RVS4_GORGO FADD FADD S100A8 S100A8 CCL3 CCL3 PLA2G3 PLA2G3 G3RXL1_GORGO G3RXL1_GORGO TLR7 TLR7 MAP3K7 MAP3K7 C2CD4D C2CD4D NFKBIZ NFKBIZ TRIM41 TRIM41 IL17RA IL17RA SFPQ SFPQ G3S0Q7_GORGO G3S0Q7_GORGO G3S121_GORGO G3S121_GORGO G3S124_GORGO G3S124_GORGO MAPK3 MAPK3 IL2 IL2 MDK MDK TRIM5 TRIM5 NOD1 NOD1 TLR10 TLR10 NAPEPLD NAPEPLD TRIM62 TRIM62 IFNK IFNK G3S6F8_GORGO G3S6F8_GORGO PIK3CG PIK3CG G3S7P9_GORGO G3S7P9_GORGO TBK1 TBK1 CLEC6A CLEC6A EMILIN1 EMILIN1 RNF185 RNF185 C3 C3 BTK BTK CGAS CGAS PLA2G7 PLA2G7 DHX9 DHX9 TNFRSF1A TNFRSF1A TLR3 TLR3 SNCA SNCA ENSGGOP00000027573 ENSGGOP00000027573 HAVCR2 HAVCR2 FCN2 FCN2 LILRA5 LILRA5 PLCG2 PLCG2 G3SIR7_GORGO G3SIR7_GORGO C2CD4B C2CD4B HCK HCK G3SJ49_GORGO G3SJ49_GORGO IDO1 IDO1 CASP6 CASP6 SH2D1A SH2D1A ENSGGOP00000029367 ENSGGOP00000029367 ENSGGOP00000029762 ENSGGOP00000029762 ENSGGOP00000029826 ENSGGOP00000029826 ENSGGOP00000030029 ENSGGOP00000030029 ENSGGOP00000030108 ENSGGOP00000030108 ENSGGOP00000030478 ENSGGOP00000030478 CD28 CD28 ENSGGOP00000031261 ENSGGOP00000031261 ENSGGOP00000032091 ENSGGOP00000032091 PAK2 PAK2 ENSGGOP00000032880 ENSGGOP00000032880 ENSGGOP00000034709 ENSGGOP00000034709 TAFA3 TAFA3 FCGR1A FCGR1A OPTN OPTN SIN3A SIN3A RASGRP1 RASGRP1 COLEC11 COLEC11 TSLP TSLP LRRK2 LRRK2 RIOK3 RIOK3 VAMP8 VAMP8 ENSGGOP00000037798 ENSGGOP00000037798 CEBPA CEBPA KARS1 KARS1 LDLR LDLR ENSGGOP00000038632 ENSGGOP00000038632 ENSGGOP00000038747 ENSGGOP00000038747 SNX4 SNX4 ACOD1 ACOD1 ENSGGOP00000039368 ENSGGOP00000039368 MBL2 MBL2 ENSGGOP00000039847 ENSGGOP00000039847 GPR4 GPR4 CCN4 CCN4 COCH COCH ENSGGOP00000040139 ENSGGOP00000040139 IL15 IL15 IL33 IL33 PDCD4 PDCD4 NAIP NAIP GPRC5B GPRC5B ENSGGOP00000043190 ENSGGOP00000043190 TNIP1 TNIP1 LSM14A LSM14A ENSGGOP00000043564 ENSGGOP00000043564 POLR3B POLR3B IRF7 IRF7 CEBPB CEBPB ENSGGOP00000045267 ENSGGOP00000045267 NLRP6 NLRP6 ENSGGOP00000045477 ENSGGOP00000045477 CADM1 CADM1 ENSGGOP00000046335 ENSGGOP00000046335 TNFRSF11A TNFRSF11A POLR3G POLR3G ENSGGOP00000046758 ENSGGOP00000046758 NUPR1 NUPR1 ENSGGOP00000048129 ENSGGOP00000048129 ENSGGOP00000049861 ENSGGOP00000049861 APP APP ENSGGOP00000050481 ENSGGOP00000050481 PTGER3 PTGER3 ENSGGOP00000050852 ENSGGOP00000050852 ENSGGOP00000051997 ENSGGOP00000051997 ENSGGOP00000051962 ENSGGOP00000051962
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FCN3Ficolin 3. (299 aa)
STAP1Signal transducing adaptor family member 1. (295 aa)
EMILIN2Elastin microfibril interfacer 2. (1031 aa)
TRIM56Tripartite motif containing 56. (755 aa)
TTBK1Tau tubulin kinase 1. (1322 aa)
CX3CL1C-X3-C motif chemokine ligand 1. (397 aa)
LRSAM1Leucine rich repeat and sterile alpha motif containing 1. (723 aa)
S100A9Protein S100; Belongs to the S-100 family. (114 aa)
KLK5Kallikrein related peptidase 5; Belongs to the peptidase S1 family. (293 aa)
C2CD4CC2 calcium dependent domain containing 4C. (421 aa)
MASP1Mannan binding lectin serine peptidase 1; Belongs to the peptidase S1 family. (728 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1181 aa)
ADORA2BAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (332 aa)
IL23AInterleukin 23 subunit alpha. (189 aa)
GBP5Guanylate binding protein 5. (586 aa)
CTSCCathepsin C; Belongs to the peptidase C1 family. (463 aa)
GPSM3G protein signaling modulator 3. (157 aa)
AKIRIN2Akirin 2. (203 aa)
GRPGastrin releasing peptide. (138 aa)
PGCProgastricsin; Belongs to the peptidase A1 family. (388 aa)
NLRC4NLR family CARD domain containing 4. (1024 aa)
ETS1ETS proto-oncogene 1, transcription factor. (485 aa)
LAMP1Lysosomal associated membrane protein 1. (465 aa)
TLR2Toll-like receptor 2; Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). May also promote apoptosis in response to lipoproteins. Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequentl [...] (784 aa)
PAK1Non-specific serine/threonine protein kinase. (554 aa)
LAG3Lymphocyte activating 3. (525 aa)
UBE2KUbiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family. (200 aa)
PSPC1Paraspeckle component 1. (523 aa)
POMCProopiomelanocortin. (267 aa)
TOMM70Translocase of outer mitochondrial membrane 70. (608 aa)
LGALS2Galectin. (132 aa)
EREGEGF-like domain-containing protein. (222 aa)
HPXHemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. (462 aa)
G3QN85_GORGOSLAM family member 6. (331 aa)
SUCNR1Succinate receptor 1; Belongs to the G-protein coupled receptor 1 family. (333 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (328 aa)
NPY5RNeuropeptide Y receptor Y5. (445 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (871 aa)
AP1G1AP-1 complex subunit gamma. (825 aa)
CCL24SCY domain-containing protein. (64 aa)
MGST2Microsomal glutathione S-transferase 2. (147 aa)
IL17FInterleukin 17F. (163 aa)
IL16Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. (1331 aa)
G3QRS4_GORGOZP domain-containing protein. (290 aa)
FPR2N-formyl peptide receptor 2; Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophil chemotactic factors (By similarity). Binding of FMLP to the receptor causes activation of neutrophils (By similarity). This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system (By similarity). Receptor for the chemokine-like protein FAM19A5, mediating FAM19A5- stimulated macrophage chemotaxis and the inhibitory effect on TNFSF11/RANKL-induced osteoclast differentiation (By similarity). (350 aa)
CLOCKClock circadian regulator. (847 aa)
TNFSF18TNF superfamily member 18. (199 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
FFAR2Free fatty acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (330 aa)
MNDAMyeloid cell nuclear differentiation antigen. (407 aa)
G3QT71_GORGOLymphotoxin alpha; Belongs to the tumor necrosis factor family. (205 aa)
G3QT76_GORGOTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
CREBBPCREB binding protein. (2436 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
CD226CD226 molecule. (336 aa)
G3QTD2_GORGOProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (3503 aa)
IFI16Interferon gamma inducible protein 16. (785 aa)
AIM2Absent in melanoma 2. (343 aa)
NONOUncharacterized protein. (441 aa)
CCDC142Coiled-coil domain containing 142. (743 aa)
NECTIN2Nectin cell adhesion molecule 2. (539 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa)
NPAS2Neuronal PAS domain protein 2. (824 aa)
SPI1Spi-1 proto-oncogene. (271 aa)
G3QUX8_GORGOCalcium/calmodulin dependent protein kinase II inhibitor 1. (78 aa)
S100A12S100 calcium binding protein A12; Belongs to the S-100 family. (92 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (762 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa)
CLNKCytokine dependent hematopoietic cell linker. (428 aa)
PLA2G5Phospholipase A(2). (138 aa)
G3QVM2_GORGOKiller cell lectin like receptor K1. (216 aa)
COLEC10Collectin subfamily member 10. (277 aa)
F2RL1F2R like trypsin receptor 1. (397 aa)
HYAL2Hyaluronidase. (473 aa)
OSMOncostatin M. (252 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (402 aa)
POLR3CRNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (534 aa)
POLR3DRNA polymerase III subunit D. (398 aa)
G3QWJ4_GORGOUncharacterized protein. (895 aa)
FABP4Fatty acid binding protein 4; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
G3QX51_GORGOLipopolysaccharide binding protein. (481 aa)
CD81Tetraspanin. (260 aa)
G3QXA0_GORGOSCY domain-containing protein. (53 aa)
PTGER4Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (490 aa)
CD47CD47 molecule. (323 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
FYNTyrosine-protein kinase. (537 aa)
EP300E1A binding protein p300. (2416 aa)
PLA2G2APhospholipase A(2). (144 aa)
ZNFX1Zinc finger NFX1-type containing 1. (1918 aa)
G3R037_GORGOFem-1 homolog A. (653 aa)
DDTLUncharacterized protein. (164 aa)
MMP8Matrix metallopeptidase 8. (467 aa)
IFI35Interferon induced protein 35. (286 aa)
NLRP12NLR family pyrin domain containing 12. (1065 aa)
NLRP10NLR family pyrin domain containing 10. (661 aa)
TXKTyrosine-protein kinase. (527 aa)
MMRN2Multimerin 2. (838 aa)
RAET1EMHC_I-like_Ag-recog domain-containing protein. (263 aa)
NFKBIANFKB inhibitor alpha. (317 aa)
G3R212_GORGORNA binding motif protein 14. (669 aa)
IL17AInterleukin 17A. (155 aa)
NLRC5NLR family CARD domain containing 5. (1866 aa)
G3R3U7_GORGOMitochondrial antiviral signaling protein. (481 aa)
SYKTyrosine-protein kinase. (635 aa)
KLRD1Killer cell lectin like receptor D1. (179 aa)
G3R570_GORGOUncharacterized protein. (274 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1040 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa)
ZBP1Z-DNA binding protein 1. (429 aa)
TNFSF11Tumor necrosis factor ligand superfamily member. (317 aa)
LGALS1Galectin. (135 aa)
PQBP1Polyglutamine-binding protein 1; Intrinsically disordered protein that acts as a scaffold, and which is involved in different processes, such as pre-mRNA splicing, transcription regulation, innate immunity and neuron development. Interacts with splicing-related factors via the intrinsically disordered region and regulates alternative splicing of target pre-mRNA species. May suppress the ability of POU3F2 to transactivate the DRD1 gene in a POU3F2 dependent manner. Can activate transcription directly or via association with the transcription machinery. May be involved in ATXN1 mutant-in [...] (265 aa)
NLRP1NLR family pyrin domain containing 1. (1471 aa)
XRCC5X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (732 aa)
POLR3FDNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (316 aa)
UCNUrocortin. (124 aa)
TRADDDeath domain-containing protein. (251 aa)
G3R8T5_GORGOParkinsonism associated deglycase. (155 aa)
USP27XUbiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (438 aa)
VAV1Vav guanine nucleotide exchange factor 1. (788 aa)
TLR8Toll like receptor 8; Belongs to the Toll-like receptor family. (1059 aa)
PYHIN1Pyrin and HIN domain family member 1. (492 aa)
LYNTyrosine-protein kinase. (512 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (671 aa)
G3RAJ9_GORGOCyclin dependent kinase 19. (446 aa)
G3RAL4_GORGOMajor histocompatibility complex, class I, E; Belongs to the MHC class I family. (354 aa)
NMIN-myc and STAT interactor. (307 aa)
G3RD62_GORGOUncharacterized protein. (488 aa)
ALOX5APArachidonate 5-lipoxygenase activating protein. (218 aa)
G3RE11_GORGOSH2 domain containing 1B. (110 aa)
HEXIM1HEXIM P-TEFb complex subunit 1. (359 aa)
SLC15A4Solute carrier family 15 member 4. (577 aa)
PDE2APhosphodiesterase. (941 aa)
NKG7Natural killer cell granule protein 7. (165 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (230 aa)
RPS19Ribosomal protein S19. (145 aa)
TYROBPTYRO protein tyrosine kinase binding protein. (113 aa)
G3RI71_GORGONACHT domain-containing protein. (1127 aa)
G3RID2_GORGOTIR domain-containing protein. (1033 aa)
GRNGranulin precursor. (593 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
XRCC6X-ray repair cross complementing 6. (609 aa)
PARP9Poly(ADP-ribose) polymerase family member 9. (819 aa)
RNF31Uncharacterized protein. (1072 aa)
STING1Transmembrane protein 173. (379 aa)
PENKProenkephalin. (267 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa)
IL1RL1Interleukin 1 receptor like 1. (556 aa)
G3RKL3_GORGOMHC_I-like_Ag-recog domain-containing protein. (393 aa)
GRPRGastrin releasing peptide receptor; Belongs to the G-protein coupled receptor 1 family. (384 aa)
PYCARDPYD and CARD domain containing. (195 aa)
IFNB1Interferon beta 1. (187 aa)
MMP12Matrix metallopeptidase 12. (470 aa)
NINJ1Ninjurin 1. (152 aa)
CCR2C-C motif chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family. (374 aa)
CRTAMCytotoxic and regulatory T cell molecule. (393 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
G3RQF4_GORGOLeukocyte immunoglobulin like receptor A2. (483 aa)
G3RR23_GORGOUncharacterized protein. (210 aa)
G3RR32_GORGOUncharacterized protein. (382 aa)
SRCTyrosine-protein kinase. (542 aa)
CCL1C-C motif chemokine. (96 aa)
G3RRC5_GORGOUncharacterized protein. (491 aa)
TNFSF4TNF superfamily member 4; Belongs to the tumor necrosis factor family. (183 aa)
ARG1Arginase. (322 aa)
IL6Interleukin 6. (234 aa)
IRGMImmunity related GTPase M. (181 aa)
TIRAPTIR domain containing adaptor protein. (221 aa)
G3RT38_GORGOADAM metallopeptidase domain 8. (824 aa)
G3RT49_GORGOcAMP responsive element binding protein 3 like 3. (461 aa)
KLK3Kallikrein related peptidase 3; Belongs to the peptidase S1 family. (223 aa)
PLSCR1Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (318 aa)
G3RUA1_GORGOIGc1 domain-containing protein; Belongs to the MHC class I family. (398 aa)
MASP2Mannan binding lectin serine peptidase 2; Belongs to the peptidase S1 family. (686 aa)
CXHXorf21Chromosome X open reading frame 21. (301 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (716 aa)
G3RVM4_GORGOUncharacterized protein. (158 aa)
G3RVS4_GORGOSignal transducer and activator of transcription. (787 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
S100A8Protein S100; Belongs to the S-100 family. (93 aa)
CCL3C-C motif chemokine. (92 aa)
PLA2G3Phospholipase A2 group III. (539 aa)
G3RXL1_GORGOIg-like domain-containing protein. (175 aa)
TLR7Toll like receptor 7; Belongs to the Toll-like receptor family. (1049 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (579 aa)
C2CD4DC2 calcium dependent domain containing 4D. (353 aa)
NFKBIZNFKB inhibitor zeta. (718 aa)
TRIM41Tripartite motif containing 41. (612 aa)
IL17RAInterleukin 17 receptor A. (865 aa)
SFPQSplicing factor proline and glutamine rich. (590 aa)
G3S0Q7_GORGOSET domain containing 4. (440 aa)
G3S121_GORGOUncharacterized protein. (261 aa)
G3S124_GORGOKiller cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3. (405 aa)
MAPK3Mitogen-activated protein kinase. (322 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (153 aa)
MDKMidkine. (143 aa)
TRIM5Tripartite motif-containing protein 5; Capsid-specific restriction factor that prevents infection from non-host-adapted retroviruses. Blocks viral replication early in the life cycle, after viral entry but before reverse transcription. In addition to acting as a capsid-specific restriction factor, also acts as a pattern recognition receptor that activates innate immune signaling in response to the retroviral capsid lattice. Binding to the viral capsid triggers its E3 ubiquitin ligase activity, and in concert with the heterodimeric ubiquitin conjugating enzyme complex UBE2V1- UBE2N (als [...] (493 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (953 aa)
TLR10Toll-like receptor. (811 aa)
NAPEPLDN-acyl phosphatidylethanolamine phospholipase D. (393 aa)
TRIM62Tripartite motif containing 62. (475 aa)
IFNKInterferon kappa. (207 aa)
G3S6F8_GORGOMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1514 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa)
G3S7P9_GORGOUncharacterized protein. (128 aa)
TBK1TANK binding kinase 1. (729 aa)
CLEC6AC-type lectin domain containing 6A. (209 aa)
EMILIN1Elastin microfibril interfacer 1. (1016 aa)
RNF185Ring finger protein 185. (192 aa)
C3Complement C3. (1663 aa)
BTKTyrosine-protein kinase. (693 aa)
CGASCyclic GMP-AMP synthase. (447 aa)
PLA2G7Platelet-activating factor acetylhydrolase. (441 aa)
DHX9DExH-box helicase 9. (1270 aa)
TNFRSF1ATNF receptor superfamily member 1A. (455 aa)
TLR3Toll-like receptor 3 precursor; Belongs to the Toll-like receptor family. (904 aa)
SNCAAlpha-synuclein; Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs [...] (140 aa)
ENSGGOP00000027573annotation not available (93 aa)
HAVCR2Hepatitis A virus cellular receptor 2. (301 aa)
FCN2Ficolin 2. (313 aa)
LILRA5Leukocyte immunoglobulin like receptor A5. (300 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
G3SIR7_GORGOKu domain-containing protein. (334 aa)
C2CD4BC2 calcium dependent domain containing 4B. (355 aa)
HCKTyrosine-protein kinase. (526 aa)
G3SJ49_GORGOKallikrein related peptidase 7; Belongs to the peptidase S1 family. (252 aa)
IDO1Indoleamine 2,3-dioxygenase 1. (403 aa)
CASP6Caspase 6; Belongs to the peptidase C14A family. (293 aa)
SH2D1ASH2 domain-containing protein 1A; Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2. (128 aa)
ENSGGOP00000029367Pyrin domain-containing protein. (110 aa)
ENSGGOP00000029762DJ-1_PfpI domain-containing protein. (168 aa)
ENSGGOP00000029826Uncharacterized protein. (123 aa)
ENSGGOP00000030029ATP binding cassette subfamily C member 1. (1479 aa)
ENSGGOP00000030108Ku domain-containing protein. (592 aa)
ENSGGOP00000030478Tyrosine-protein kinase. (1151 aa)
CD28CD28 molecule. (220 aa)
ENSGGOP00000031261Myocyte enhancer factor 2C. (483 aa)
ENSGGOP00000032091Caspase 4; Belongs to the peptidase C14A family. (377 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
ENSGGOP00000032880Zinc finger CCHC-type containing 3. (328 aa)
ENSGGOP00000034709Uncharacterized protein. (192 aa)
TAFA3Uncharacterized protein. (147 aa)
FCGR1AUncharacterized protein. (374 aa)
OPTNOptineurin. (577 aa)
SIN3AUncharacterized protein. (154 aa)
RASGRP1RAS guanyl releasing protein 1. (848 aa)
COLEC11Collectin subfamily member 11. (285 aa)
TSLPThymic stromal lymphopoietin. (159 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
RIOK3RIO domain-containing protein. (311 aa)
VAMP8V-SNARE coiled-coil homology domain-containing protein. (113 aa)
ENSGGOP00000037798Uncharacterized protein. (246 aa)
CEBPABZIP domain-containing protein. (141 aa)
KARS1Lysine--tRNA ligase. (629 aa)
LDLRLow density lipoprotein receptor. (859 aa)
ENSGGOP00000038632RRM domain-containing protein. (533 aa)
ENSGGOP00000038747Uncharacterized protein. (1063 aa)
SNX4Sorting nexin 4. (450 aa)
ACOD1Aconitate decarboxylase 1. (481 aa)
ENSGGOP00000039368RRM domain-containing protein. (153 aa)
MBL2Mannose-binding protein C; Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages (By similarity). (248 aa)
ENSGGOP00000039847annotation not available (241 aa)
GPR4G protein-coupled receptor 4; Belongs to the G-protein coupled receptor 1 family. (362 aa)
CCN4Cellular communication network factor 4. (368 aa)
COCHCochlin. (550 aa)
ENSGGOP00000040139Uncharacterized protein. (86 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
IL33Interleukin 33. (270 aa)
PDCD4Programmed cell death 4. (469 aa)
NAIPUncharacterized protein. (198 aa)
GPRC5BG protein-coupled receptor class C group 5 member B. (421 aa)
ENSGGOP00000043190Uncharacterized protein. (234 aa)
TNIP1TNFAIP3 interacting protein 1. (645 aa)
LSM14AUncharacterized protein. (488 aa)
ENSGGOP00000043564Interferon regulatory factor 3. (452 aa)
POLR3BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1133 aa)
IRF7Interferon regulatory factor 7. (516 aa)
CEBPBCCAAT/enhancer-binding protein. (345 aa)
ENSGGOP00000045267Uncharacterized protein; Belongs to the peptidase C14A family. (342 aa)
NLRP6Uncharacterized protein. (912 aa)
ENSGGOP00000045477Non-specific serine/threonine protein kinase. (530 aa)
CADM1Cell adhesion molecule 1. (450 aa)
ENSGGOP00000046335Uncharacterized protein. (118 aa)
TNFRSF11ATNF receptor superfamily member 11a. (616 aa)
POLR3GDNA-directed RNA polymerase III subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. (223 aa)
ENSGGOP00000046758Caspase 1; Belongs to the peptidase C14A family. (404 aa)
NUPR1Nuclear protein 1, transcriptional regulator. (82 aa)
ENSGGOP00000048129Caspase recruitment domain family member 9. (536 aa)
ENSGGOP00000049861Uncharacterized protein; Belongs to the synaptobrevin family. (230 aa)
APPAmyloid beta precursor protein. (771 aa)
ENSGGOP00000050481Uncharacterized protein. (441 aa)
PTGER3Prostaglandin E receptor 3. (418 aa)
ENSGGOP00000050852annotation not available (362 aa)
ENSGGOP00000051997C-type lectin domain containing 7A. (247 aa)
ENSGGOP00000051962SAP domain-containing protein. (226 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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