STRINGSTRING
G3QGD7_GORGO G3QGD7_GORGO CALM1 CALM1 TERT TERT FGF23 FGF23 TERF2 TERF2 POR POR G3QT76_GORGO G3QT76_GORGO CDH3 CDH3 IFNG IFNG IL1B IL1B FCER2 FCER2 PIK3CB PIK3CB ESR1 ESR1 G3R664_GORGO G3R664_GORGO G3R8T5_GORGO G3R8T5_GORGO C1H1orf226 C1H1orf226 NPR3 NPR3 PTK2B PTK2B VDR VDR S100A1 S100A1 HTR2B HTR2B ATP7A ATP7A NOD1 NOD1 G3SEV0_GORGO G3SEV0_GORGO NUS1 NUS1 HIF1A HIF1A CALM3 CALM3 ENSGGOP00000029762 ENSGGOP00000029762 ENSGGOP00000031235 ENSGGOP00000031235 ENSGGOP00000040681 ENSGGOP00000040681 DHFR DHFR ENSGGOP00000044877 ENSGGOP00000044877 ENSGGOP00000045523 ENSGGOP00000045523 ENSGGOP00000045621 ENSGGOP00000045621 SCARB1 SCARB1 ENSGGOP00000046735 ENSGGOP00000046735 GDNF GDNF AGTR2 AGTR2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
G3QGD7_GORGOCytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (508 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (150 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1132 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (251 aa)
TERF2Telomeric repeat binding factor 2. (542 aa)
PORNADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (680 aa)
G3QT76_GORGOTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
CDH3Cadherin 3; Cadherins are calcium-dependent cell adhesion proteins. (829 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa)
FCER2Fc fragment of IgE receptor II. (321 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1041 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
G3R664_GORGOUncharacterized protein. (226 aa)
G3R8T5_GORGOParkinsonism associated deglycase. (155 aa)
C1H1orf226Nitric oxide synthase 1 adaptor protein. (506 aa)
NPR3Natriuretic peptide receptor 3. (541 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
VDRVitamin D receptor. (477 aa)
S100A1Protein S100; Belongs to the S-100 family. (147 aa)
HTR2B5-hydroxytryptamine receptor 2B. (481 aa)
ATP7AATPase copper transporting alpha. (1500 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (953 aa)
G3SEV0_GORGOUncharacterized protein; Belongs to the calmodulin family. (152 aa)
NUS1NUS1 dehydrodolichyl diphosphate synthase subunit. (293 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (850 aa)
CALM3Calmodulin 1; Belongs to the calmodulin family. (149 aa)
ENSGGOP00000029762DJ-1_PfpI domain-containing protein. (168 aa)
ENSGGOP00000031235Uncharacterized protein; Belongs to the calmodulin family. (129 aa)
ENSGGOP00000040681Uncharacterized protein; Belongs to the calmodulin family. (70 aa)
DHFRDihydrofolate reductase; Belongs to the dihydrofolate reductase family. (187 aa)
ENSGGOP00000044877Uncharacterized protein; Belongs to the calmodulin family. (123 aa)
ENSGGOP00000045523Uncharacterized protein. (281 aa)
ENSGGOP00000045621Uncharacterized protein. (252 aa)
SCARB1Scavenger receptor class B member 1; Belongs to the CD36 family. (509 aa)
ENSGGOP00000046735Non-specific serine/threonine protein kinase. (524 aa)
GDNFGlial cell derived neurotrophic factor. (228 aa)
AGTR2Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. (363 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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