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ENSGGOP00000049072 | Protein kinase domain-containing protein. (296 aa) | ||||
PKM | Pyruvate kinase; Belongs to the pyruvate kinase family. (556 aa) | ||||
RAB8A | RAB8A, member RAS oncogene family. (207 aa) | ||||
EIF6 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] (257 aa) | ||||
DENND4C | DENN domain containing 4C. (1958 aa) | ||||
PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (723 aa) | ||||
SREBF1 | Sterol regulatory element binding transcription factor 1. (1177 aa) | ||||
ENSGGOP00000051000 | Uncharacterized protein. (107 aa) | ||||
GHR | Growth hormone receptor. (656 aa) | ||||
LPIN3 | Lipin 3. (852 aa) | ||||
BCAR1 | BCAR1 scaffold protein, Cas family member. (916 aa) | ||||
GAB1 | GRB2 associated binding protein 1. (724 aa) | ||||
GAL | Galanin and GMAP prepropeptide. (123 aa) | ||||
LPIN2 | Lipin 2. (896 aa) | ||||
UCP3 | Uncoupling protein 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. (312 aa) | ||||
MEAK7 | MTOR associated protein, eak-7 homolog. (456 aa) | ||||
LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (167 aa) | ||||
CDK4 | Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) | ||||
CAPN10 | Calpain 10; Belongs to the peptidase C2 family. (672 aa) | ||||
GCK | Phosphotransferase. (466 aa) | ||||
SLC9A1 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa) | ||||
BCAR3 | BCAR3 adaptor protein, NSP family member. (825 aa) | ||||
G3QH42_GORGO | Otopetrin 1. (611 aa) | ||||
PHIP | Pleckstrin homology domain interacting protein. (1810 aa) | ||||
POU4F2 | POU domain protein. (407 aa) | ||||
PKLR | Pyruvate kinase; Belongs to the pyruvate kinase family. (574 aa) | ||||
PFKFB1 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1. (471 aa) | ||||
CRY2 | Cryptochrome circadian regulator 2. (614 aa) | ||||
SRSF4 | Serine and arginine rich splicing factor 4. (494 aa) | ||||
PDK4 | Protein-serine/threonine kinase. (411 aa) | ||||
GOT1 | Aspartate aminotransferase. (413 aa) | ||||
KHK | Ketohexokinase. (298 aa) | ||||
G3QJL7_GORGO | Uncharacterized protein. (65 aa) | ||||
ZBED3 | Zinc finger BED-type containing 3. (234 aa) | ||||
SLC22A12 | Solute carrier family 22 member 12. (553 aa) | ||||
SLC39A14 | Solute carrier family 39 member 14. (490 aa) | ||||
UCP2 | Uncoupling protein 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (309 aa) | ||||
RABGAP1 | RAB GTPase activating protein 1. (1069 aa) | ||||
USF1 | Upstream transcription factor 1. (310 aa) | ||||
KBTBD2 | Kelch repeat and BTB domain containing 2. (623 aa) | ||||
DNAI1 | Dynein axonemal intermediate chain 1. (699 aa) | ||||
TRPV4 | Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (871 aa) | ||||
GSK3A | Glycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (483 aa) | ||||
CSRP3 | Cysteine and glycine rich protein 3. (194 aa) | ||||
SESN3 | Sestrin 3. (492 aa) | ||||
SLC27A1 | Solute carrier family 27 member 1. (646 aa) | ||||
PTPRA | Receptor-type tyrosine-protein phosphatase alpha. (802 aa) | ||||
EGR2 | Early growth response 2. (476 aa) | ||||
FBP1 | Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family. (338 aa) | ||||
G3QTD2_GORGO | Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (3503 aa) | ||||
GRB2 | Growth factor receptor bound protein 2. (217 aa) | ||||
MYO5A | Myosin VA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1856 aa) | ||||
ERRFI1 | ERBB receptor feedback inhibitor 1. (462 aa) | ||||
GRB10 | Growth factor receptor bound protein 10. (594 aa) | ||||
SORT1 | Sortilin. (831 aa) | ||||
RAB15 | Uncharacterized protein. (208 aa) | ||||
TRARG1 | Uncharacterized protein. (248 aa) | ||||
PLA2G1B | Phospholipase A(2). (148 aa) | ||||
GCLC | Glutamate-cysteine ligase catalytic subunit. (637 aa) | ||||
PDE3B | Phosphodiesterase. (1113 aa) | ||||
PTPN1 | Tyrosine-protein phosphatase non-receptor type. (435 aa) | ||||
STXBP3 | Syntaxin binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (592 aa) | ||||
KL | Uncharacterized protein; Belongs to the glycosyl hydrolase 1 family. (739 aa) | ||||
GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (481 aa) | ||||
INPP5K | Inositol polyphosphate-5-phosphatase K. (448 aa) | ||||
SLC2A4 | Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa) | ||||
TRIB3 | Tribbles pseudokinase 3. (385 aa) | ||||
ZNF106 | Zinc finger protein 106. (1883 aa) | ||||
SLC29A2 | Solute carrier family 29 member 2. (456 aa) | ||||
FOXO1 | Forkhead box O1. (655 aa) | ||||
PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) | ||||
RETN | Resistin. (108 aa) | ||||
RPE65 | Retinoid isomerohydrolase RPE65. (533 aa) | ||||
SRSF6 | Serine and arginine rich splicing factor 6. (344 aa) | ||||
KLF15 | Kruppel like factor 15. (416 aa) | ||||
FER | Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa) | ||||
SIRT1 | Sirtuin 1. (751 aa) | ||||
HMGCS2 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa) | ||||
MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2520 aa) | ||||
G3R515_GORGO | Protein kinase C iota. (557 aa) | ||||
CAT | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa) | ||||
G3R577_GORGO | Insulin like growth factor binding protein 1. (259 aa) | ||||
IDE | Insulin degrading enzyme; Belongs to the peptidase M16 family. (1019 aa) | ||||
CFLAR | CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (480 aa) | ||||
PCK1 | Phosphoenolpyruvate carboxykinase 1. (622 aa) | ||||
ENPP1 | Ectonucleotide pyrophosphatase/phosphodiesterase 1. (896 aa) | ||||
ADM | Adrenomedullin. (185 aa) | ||||
OTC | Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (354 aa) | ||||
G3R883_GORGO | ANK_REP_REGION domain-containing protein. (1226 aa) | ||||
STXBP4 | Syntaxin binding protein 4. (553 aa) | ||||
EPRS1 | Glutamyl-prolyl-tRNA synthetase. (1515 aa) | ||||
LYN | Tyrosine-protein kinase. (512 aa) | ||||
G3RA25_GORGO | Sp1 transcription factor. (786 aa) | ||||
APRT | Adenine phosphoribosyltransferase. (180 aa) | ||||
IGF1R | Tyrosine-protein kinase receptor. (1367 aa) | ||||
HSD11B2 | Hydroxysteroid 11-beta dehydrogenase 2. (405 aa) | ||||
AGRP | Agouti related neuropeptide. (132 aa) | ||||
PRKCZ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa) | ||||
KCNQ1 | Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (676 aa) | ||||
SHC1 | SHC adaptor protein 1. (584 aa) | ||||
ZBTB7B | Zinc finger and BTB domain containing 7B. (573 aa) | ||||
NCOA5 | Nuclear receptor coactivator 5. (579 aa) | ||||
INSRR | Tyrosine-protein kinase receptor. (1297 aa) | ||||
GALP | Galanin like peptide. (116 aa) | ||||
G3REG2_GORGO | Glutamic--pyruvic transaminase. (496 aa) | ||||
SESN2 | Sestrin 2. (480 aa) | ||||
G3RF44_GORGO | Forkhead box C2. (442 aa) | ||||
OGT | O-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa) | ||||
MC4R | Melanocortin 4 receptor. (332 aa) | ||||
CAV2 | Caveolin-2; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (B [...] (162 aa) | ||||
PRLH | Prolactin releasing hormone. (87 aa) | ||||
G3RGU1_GORGO | ANK_REP_REGION domain-containing protein. (307 aa) | ||||
RARRES2 | Retinoic acid receptor responder 2. (163 aa) | ||||
ENSGGOP00000048053 | RRM domain-containing protein. (183 aa) | ||||
ENSGGOP00000047857 | Uncharacterized protein. (1276 aa) | ||||
IGF2 | Insulin like growth factor 2. (236 aa) | ||||
EIF4EBP2 | Eukaryotic translation initiation factor 4E binding protein 2. (120 aa) | ||||
VPS13C | Vacuolar protein sorting 13 homolog C. (3661 aa) | ||||
G3RF33_GORGO | Tumor necrosis factor ligand superfamily member. (281 aa) | ||||
GHRHR | Growth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (423 aa) | ||||
ENSGGOP00000046735 | Non-specific serine/threonine protein kinase. (524 aa) | ||||
CITED1 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (219 aa) | ||||
ENSGGOP00000045173 | Uncharacterized protein. (102 aa) | ||||
YWHAG | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family. (250 aa) | ||||
ENSGGOP00000044800 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (152 aa) | ||||
ENSGGOP00000043657 | Pyruvate kinase; Belongs to the pyruvate kinase family. (299 aa) | ||||
WDTC1 | WD and tetratricopeptide repeats 1. (698 aa) | ||||
ENSGGOP00000042979 | S5A_REDUCTASE domain-containing protein. (208 aa) | ||||
IRS4 | Insulin receptor substrate 4. (1254 aa) | ||||
PPARA | Peroxisome proliferator activated receptor alpha. (468 aa) | ||||
INPPL1 | Inositol polyphosphate phosphatase like 1. (1253 aa) | ||||
SLC27A4 | Solute carrier family 27 member 4. (647 aa) | ||||
ENSGGOP00000039339 | Uncharacterized protein. (632 aa) | ||||
ACVR1C | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (443 aa) | ||||
XBP1 | BZIP domain-containing protein. (380 aa) | ||||
SOGA1 | Suppressor of glucose, autophagy associated 1. (1608 aa) | ||||
CPEB1 | RRM domain-containing protein. (530 aa) | ||||
CPEB2 | Cytoplasmic polyadenylation element binding protein 2. (907 aa) | ||||
ENSGGOP00000037396 | Uncharacterized protein. (509 aa) | ||||
SCAP | SSD domain-containing protein. (338 aa) | ||||
ENSGGOP00000036972 | Uncharacterized protein. (78 aa) | ||||
ENSGGOP00000035607 | Uncharacterized protein. (125 aa) | ||||
LPIN1 | Lipin 1. (975 aa) | ||||
ZFP36L1 | ZFP36 ring finger protein like 1. (338 aa) | ||||
ENSGGOP00000034697 | Hydroxyacyl-CoA dehydrogenase. (390 aa) | ||||
AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) | ||||
GPLD1 | Glycosylphosphatidylinositol specific phospholipase D1. (840 aa) | ||||
PPARG | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa) | ||||
MAX | MYC associated factor X. (148 aa) | ||||
IRS1 | Insulin receptor substrate 1. (1241 aa) | ||||
C2CD5 | C2 calcium dependent domain containing 5. (1084 aa) | ||||
EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (543 aa) | ||||
BAIAP2 | BAI1 associated protein 2. (548 aa) | ||||
ENSGGOP00000030268 | Uncharacterized protein. (596 aa) | ||||
ENSGGOP00000030210 | Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (612 aa) | ||||
SELENOS | Uncharacterized protein. (218 aa) | ||||
ADIPOQ | Adiponectin, C1Q and collagen domain containing. (244 aa) | ||||
ENSGGOP00000028878 | Forkhead box O4. (505 aa) | ||||
G3SKI0_GORGO | Uncharacterized protein. (1294 aa) | ||||
VGF | Uncharacterized protein. (336 aa) | ||||
TSC1 | TSC complex subunit 1. (1164 aa) | ||||
HADHA | Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. (763 aa) | ||||
RAB31 | RAB31, member RAS oncogene family. (195 aa) | ||||
G3SHS9_GORGO | ANK_REP_REGION domain-containing protein. (499 aa) | ||||
PNPLA3 | Patatin like phospholipase domain containing 3. (447 aa) | ||||
SLC2A8 | Solute carrier family 2 member 8; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (454 aa) | ||||
STAT1 | Signal transducer and activator of transcription. (777 aa) | ||||
GHSR | Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa) | ||||
GRB14 | Growth factor receptor bound protein 14. (476 aa) | ||||
G3SCN9_GORGO | Uncharacterized protein. (572 aa) | ||||
PARP1 | Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa) | ||||
CRY1 | Cryptochrome circadian regulator 1. (623 aa) | ||||
G3SAN6_GORGO | Ankyrin repeat domain 30A. (1318 aa) | ||||
PDPK1 | Protein kinase domain-containing protein. (347 aa) | ||||
RAB13 | Uncharacterized protein. (203 aa) | ||||
HDAC9 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1066 aa) | ||||
PTPN2 | Tyrosine-protein phosphatase non-receptor type. (387 aa) | ||||
G3S7H0_GORGO | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (646 aa) | ||||
NDEL1 | NudE neurodevelopment protein 1 like 1. (345 aa) | ||||
PCSK9 | Proprotein convertase subtilisin/kexin type 9; Crucial player in the regulation of plasma cholesterol homeostasis. Binds to low-density lipid receptor family members: low density lipoprotein receptor (LDLR), very low density lipoprotein receptor (VLDLR), apolipoprotein E receptor (LRP1/APOER) and apolipoprotein receptor 2 (LRP8/APOER2), and promotes their degradation in intracellular acidic compartments. Acts via a non-proteolytic mechanism to enhance the degradation of the hepatic LDLR through a clathrin LDLRAP1/ARH-mediated pathway. May prevent the recycling of LDLR from endosomes to [...] (690 aa) | ||||
CEACAM1 | Carcinoembryonic antigen related cell adhesion molecule 1. (525 aa) | ||||
CYFIP1 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa) | ||||
SLC25A33 | Solute carrier family 25 member 33; Belongs to the mitochondrial carrier (TC 2.A.29) family. (321 aa) | ||||
SLC2A1 | Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (492 aa) | ||||
G3RY68_GORGO | Chymotrypsin like elastase 2A; Belongs to the peptidase S1 family. (269 aa) | ||||
G3RXW1_GORGO | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (372 aa) | ||||
SYAP1 | Synapse associated protein 1. (352 aa) | ||||
EPM2AIP1 | EPM2A interacting protein 1. (607 aa) | ||||
KAT2B | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (820 aa) | ||||
RAB10 | RAB10, member RAS oncogene family. (200 aa) | ||||
AP3S1 | Clat_adaptor_s domain-containing protein. (193 aa) | ||||
HDAC5 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1122 aa) | ||||
G3RTJ0_GORGO | Ras homolog family member Q. (200 aa) | ||||
PIK3R3 | Uncharacterized protein. (507 aa) | ||||
RPS6KB1 | Protein kinase domain-containing protein. (210 aa) | ||||
G3RT31_GORGO | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (277 aa) | ||||
G3RSU6_GORGO | Uncharacterized protein. (499 aa) | ||||
PIK3C2A | Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1686 aa) | ||||
APC | APC regulator of WNT signaling pathway. (2844 aa) | ||||
SRC | Tyrosine-protein kinase. (542 aa) | ||||
INSR | Tyrosine-protein kinase receptor. (1347 aa) | ||||
G3RPB0_GORGO | Uncharacterized protein. (351 aa) | ||||
G3RMA5_GORGO | Tyrosine-protein phosphatase non-receptor type. (415 aa) | ||||
G3RLC3_GORGO | SH2 domain-containing protein. (568 aa) | ||||
SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1. (1054 aa) | ||||
G3RKQ9_GORGO | CCDC144C domain-containing protein. (314 aa) | ||||
G3RKH1_GORGO | Zinc finger DHHC-type containing 7. (312 aa) | ||||
SRD5A1 | 3-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (259 aa) | ||||
SRSF5 | Serine and arginine rich splicing factor 5. (272 aa) | ||||
G3RJZ9_GORGO | RB transcriptional corepressor 1. (756 aa) | ||||
ABCC8 | ATP binding cassette subfamily C member 8. (1582 aa) | ||||
INSIG2 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (225 aa) | ||||
TBC1D4 | TBC1 domain family member 4. (1298 aa) | ||||
PDK2 | Protein-serine/threonine kinase. (407 aa) | ||||
IRS2 | Insulin receptor substrate 2. (1220 aa) | ||||
INHBB | Inhibin subunit beta B. (407 aa) | ||||
G3RGY7_GORGO | Eukaryotic elongation factor 2 kinase. (638 aa) |