STRINGSTRING
ENSGGOP00000049072 ENSGGOP00000049072 PKM PKM RAB8A RAB8A EIF6 EIF6 DENND4C DENND4C PIK3R1 PIK3R1 SREBF1 SREBF1 ENSGGOP00000051000 ENSGGOP00000051000 GHR GHR LPIN3 LPIN3 BCAR1 BCAR1 GAB1 GAB1 GAL GAL LPIN2 LPIN2 UCP3 UCP3 MEAK7 MEAK7 LEP LEP CDK4 CDK4 CAPN10 CAPN10 GCK GCK SLC9A1 SLC9A1 BCAR3 BCAR3 G3QH42_GORGO G3QH42_GORGO PHIP PHIP POU4F2 POU4F2 PKLR PKLR PFKFB1 PFKFB1 CRY2 CRY2 SRSF4 SRSF4 PDK4 PDK4 GOT1 GOT1 KHK KHK G3QJL7_GORGO G3QJL7_GORGO ZBED3 ZBED3 SLC22A12 SLC22A12 SLC39A14 SLC39A14 UCP2 UCP2 RABGAP1 RABGAP1 USF1 USF1 KBTBD2 KBTBD2 DNAI1 DNAI1 TRPV4 TRPV4 GSK3A GSK3A CSRP3 CSRP3 SESN3 SESN3 SLC27A1 SLC27A1 PTPRA PTPRA EGR2 EGR2 FBP1 FBP1 G3QTD2_GORGO G3QTD2_GORGO GRB2 GRB2 MYO5A MYO5A ERRFI1 ERRFI1 GRB10 GRB10 SORT1 SORT1 RAB15 RAB15 TRARG1 TRARG1 PLA2G1B PLA2G1B GCLC GCLC PDE3B PDE3B PTPN1 PTPN1 STXBP3 STXBP3 KL KL GSK3B GSK3B INPP5K INPP5K SLC2A4 SLC2A4 TRIB3 TRIB3 ZNF106 ZNF106 SLC29A2 SLC29A2 FOXO1 FOXO1 PIK3CA PIK3CA RETN RETN RPE65 RPE65 SRSF6 SRSF6 KLF15 KLF15 FER FER SIRT1 SIRT1 HMGCS2 HMGCS2 MTOR MTOR G3R515_GORGO G3R515_GORGO CAT CAT G3R577_GORGO G3R577_GORGO IDE IDE CFLAR CFLAR PCK1 PCK1 ENPP1 ENPP1 ADM ADM OTC OTC G3R883_GORGO G3R883_GORGO STXBP4 STXBP4 EPRS1 EPRS1 LYN LYN G3RA25_GORGO G3RA25_GORGO APRT APRT IGF1R IGF1R HSD11B2 HSD11B2 AGRP AGRP PRKCZ PRKCZ KCNQ1 KCNQ1 SHC1 SHC1 ZBTB7B ZBTB7B NCOA5 NCOA5 INSRR INSRR GALP GALP G3REG2_GORGO G3REG2_GORGO SESN2 SESN2 G3RF44_GORGO G3RF44_GORGO OGT OGT MC4R MC4R CAV2 CAV2 PRLH PRLH G3RGU1_GORGO G3RGU1_GORGO RARRES2 RARRES2 ENSGGOP00000048053 ENSGGOP00000048053 ENSGGOP00000047857 ENSGGOP00000047857 IGF2 IGF2 EIF4EBP2 EIF4EBP2 VPS13C VPS13C G3RF33_GORGO G3RF33_GORGO GHRHR GHRHR ENSGGOP00000046735 ENSGGOP00000046735 CITED1 CITED1 ENSGGOP00000045173 ENSGGOP00000045173 YWHAG YWHAG ENSGGOP00000044800 ENSGGOP00000044800 ENSGGOP00000043657 ENSGGOP00000043657 WDTC1 WDTC1 ENSGGOP00000042979 ENSGGOP00000042979 IRS4 IRS4 PPARA PPARA INPPL1 INPPL1 SLC27A4 SLC27A4 ENSGGOP00000039339 ENSGGOP00000039339 ACVR1C ACVR1C XBP1 XBP1 SOGA1 SOGA1 CPEB1 CPEB1 CPEB2 CPEB2 ENSGGOP00000037396 ENSGGOP00000037396 SCAP SCAP ENSGGOP00000036972 ENSGGOP00000036972 ENSGGOP00000035607 ENSGGOP00000035607 LPIN1 LPIN1 ZFP36L1 ZFP36L1 ENSGGOP00000034697 ENSGGOP00000034697 AKT2 AKT2 GPLD1 GPLD1 PPARG PPARG MAX MAX IRS1 IRS1 C2CD5 C2CD5 EGR1 EGR1 BAIAP2 BAIAP2 ENSGGOP00000030268 ENSGGOP00000030268 ENSGGOP00000030210 ENSGGOP00000030210 SELENOS SELENOS ADIPOQ ADIPOQ ENSGGOP00000028878 ENSGGOP00000028878 G3SKI0_GORGO G3SKI0_GORGO VGF VGF TSC1 TSC1 HADHA HADHA RAB31 RAB31 G3SHS9_GORGO G3SHS9_GORGO PNPLA3 PNPLA3 SLC2A8 SLC2A8 STAT1 STAT1 GHSR GHSR GRB14 GRB14 G3SCN9_GORGO G3SCN9_GORGO PARP1 PARP1 CRY1 CRY1 G3SAN6_GORGO G3SAN6_GORGO PDPK1 PDPK1 RAB13 RAB13 HDAC9 HDAC9 PTPN2 PTPN2 G3S7H0_GORGO G3S7H0_GORGO NDEL1 NDEL1 PCSK9 PCSK9 CEACAM1 CEACAM1 CYFIP1 CYFIP1 SLC25A33 SLC25A33 SLC2A1 SLC2A1 G3RY68_GORGO G3RY68_GORGO G3RXW1_GORGO G3RXW1_GORGO SYAP1 SYAP1 EPM2AIP1 EPM2AIP1 KAT2B KAT2B RAB10 RAB10 AP3S1 AP3S1 HDAC5 HDAC5 G3RTJ0_GORGO G3RTJ0_GORGO PIK3R3 PIK3R3 RPS6KB1 RPS6KB1 G3RT31_GORGO G3RT31_GORGO G3RSU6_GORGO G3RSU6_GORGO PIK3C2A PIK3C2A APC APC SRC SRC INSR INSR G3RPB0_GORGO G3RPB0_GORGO G3RMA5_GORGO G3RMA5_GORGO G3RLC3_GORGO G3RLC3_GORGO SMARCC1 SMARCC1 G3RKQ9_GORGO G3RKQ9_GORGO G3RKH1_GORGO G3RKH1_GORGO SRD5A1 SRD5A1 SRSF5 SRSF5 G3RJZ9_GORGO G3RJZ9_GORGO ABCC8 ABCC8 INSIG2 INSIG2 TBC1D4 TBC1D4 PDK2 PDK2 IRS2 IRS2 INHBB INHBB G3RGY7_GORGO G3RGY7_GORGO
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSGGOP00000049072Protein kinase domain-containing protein. (296 aa)
PKMPyruvate kinase; Belongs to the pyruvate kinase family. (556 aa)
RAB8ARAB8A, member RAS oncogene family. (207 aa)
EIF6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] (257 aa)
DENND4CDENN domain containing 4C. (1958 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (723 aa)
SREBF1Sterol regulatory element binding transcription factor 1. (1177 aa)
ENSGGOP00000051000Uncharacterized protein. (107 aa)
GHRGrowth hormone receptor. (656 aa)
LPIN3Lipin 3. (852 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (916 aa)
GAB1GRB2 associated binding protein 1. (724 aa)
GALGalanin and GMAP prepropeptide. (123 aa)
LPIN2Lipin 2. (896 aa)
UCP3Uncoupling protein 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. (312 aa)
MEAK7MTOR associated protein, eak-7 homolog. (456 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (167 aa)
CDK4Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
CAPN10Calpain 10; Belongs to the peptidase C2 family. (672 aa)
GCKPhosphotransferase. (466 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
BCAR3BCAR3 adaptor protein, NSP family member. (825 aa)
G3QH42_GORGOOtopetrin 1. (611 aa)
PHIPPleckstrin homology domain interacting protein. (1810 aa)
POU4F2POU domain protein. (407 aa)
PKLRPyruvate kinase; Belongs to the pyruvate kinase family. (574 aa)
PFKFB16-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1. (471 aa)
CRY2Cryptochrome circadian regulator 2. (614 aa)
SRSF4Serine and arginine rich splicing factor 4. (494 aa)
PDK4Protein-serine/threonine kinase. (411 aa)
GOT1Aspartate aminotransferase. (413 aa)
KHKKetohexokinase. (298 aa)
G3QJL7_GORGOUncharacterized protein. (65 aa)
ZBED3Zinc finger BED-type containing 3. (234 aa)
SLC22A12Solute carrier family 22 member 12. (553 aa)
SLC39A14Solute carrier family 39 member 14. (490 aa)
UCP2Uncoupling protein 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (309 aa)
RABGAP1RAB GTPase activating protein 1. (1069 aa)
USF1Upstream transcription factor 1. (310 aa)
KBTBD2Kelch repeat and BTB domain containing 2. (623 aa)
DNAI1Dynein axonemal intermediate chain 1. (699 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (871 aa)
GSK3AGlycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (483 aa)
CSRP3Cysteine and glycine rich protein 3. (194 aa)
SESN3Sestrin 3. (492 aa)
SLC27A1Solute carrier family 27 member 1. (646 aa)
PTPRAReceptor-type tyrosine-protein phosphatase alpha. (802 aa)
EGR2Early growth response 2. (476 aa)
FBP1Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family. (338 aa)
G3QTD2_GORGOProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (3503 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
MYO5AMyosin VA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1856 aa)
ERRFI1ERBB receptor feedback inhibitor 1. (462 aa)
GRB10Growth factor receptor bound protein 10. (594 aa)
SORT1Sortilin. (831 aa)
RAB15Uncharacterized protein. (208 aa)
TRARG1Uncharacterized protein. (248 aa)
PLA2G1BPhospholipase A(2). (148 aa)
GCLCGlutamate-cysteine ligase catalytic subunit. (637 aa)
PDE3BPhosphodiesterase. (1113 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (435 aa)
STXBP3Syntaxin binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (592 aa)
KLUncharacterized protein; Belongs to the glycosyl hydrolase 1 family. (739 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (481 aa)
INPP5KInositol polyphosphate-5-phosphatase K. (448 aa)
SLC2A4Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
TRIB3Tribbles pseudokinase 3. (385 aa)
ZNF106Zinc finger protein 106. (1883 aa)
SLC29A2Solute carrier family 29 member 2. (456 aa)
FOXO1Forkhead box O1. (655 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
RETNResistin. (108 aa)
RPE65Retinoid isomerohydrolase RPE65. (533 aa)
SRSF6Serine and arginine rich splicing factor 6. (344 aa)
KLF15Kruppel like factor 15. (416 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
SIRT1Sirtuin 1. (751 aa)
HMGCS23-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2520 aa)
G3R515_GORGOProtein kinase C iota. (557 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa)
G3R577_GORGOInsulin like growth factor binding protein 1. (259 aa)
IDEInsulin degrading enzyme; Belongs to the peptidase M16 family. (1019 aa)
CFLARCASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (480 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase 1. (896 aa)
ADMAdrenomedullin. (185 aa)
OTCOrnithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (354 aa)
G3R883_GORGOANK_REP_REGION domain-containing protein. (1226 aa)
STXBP4Syntaxin binding protein 4. (553 aa)
EPRS1Glutamyl-prolyl-tRNA synthetase. (1515 aa)
LYNTyrosine-protein kinase. (512 aa)
G3RA25_GORGOSp1 transcription factor. (786 aa)
APRTAdenine phosphoribosyltransferase. (180 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
HSD11B2Hydroxysteroid 11-beta dehydrogenase 2. (405 aa)
AGRPAgouti related neuropeptide. (132 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (676 aa)
SHC1SHC adaptor protein 1. (584 aa)
ZBTB7BZinc finger and BTB domain containing 7B. (573 aa)
NCOA5Nuclear receptor coactivator 5. (579 aa)
INSRRTyrosine-protein kinase receptor. (1297 aa)
GALPGalanin like peptide. (116 aa)
G3REG2_GORGOGlutamic--pyruvic transaminase. (496 aa)
SESN2Sestrin 2. (480 aa)
G3RF44_GORGOForkhead box C2. (442 aa)
OGTO-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa)
MC4RMelanocortin 4 receptor. (332 aa)
CAV2Caveolin-2; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (B [...] (162 aa)
PRLHProlactin releasing hormone. (87 aa)
G3RGU1_GORGOANK_REP_REGION domain-containing protein. (307 aa)
RARRES2Retinoic acid receptor responder 2. (163 aa)
ENSGGOP00000048053RRM domain-containing protein. (183 aa)
ENSGGOP00000047857Uncharacterized protein. (1276 aa)
IGF2Insulin like growth factor 2. (236 aa)
EIF4EBP2Eukaryotic translation initiation factor 4E binding protein 2. (120 aa)
VPS13CVacuolar protein sorting 13 homolog C. (3661 aa)
G3RF33_GORGOTumor necrosis factor ligand superfamily member. (281 aa)
GHRHRGrowth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (423 aa)
ENSGGOP00000046735Non-specific serine/threonine protein kinase. (524 aa)
CITED1Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (219 aa)
ENSGGOP00000045173Uncharacterized protein. (102 aa)
YWHAGTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family. (250 aa)
ENSGGOP00000044800AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (152 aa)
ENSGGOP00000043657Pyruvate kinase; Belongs to the pyruvate kinase family. (299 aa)
WDTC1WD and tetratricopeptide repeats 1. (698 aa)
ENSGGOP00000042979S5A_REDUCTASE domain-containing protein. (208 aa)
IRS4Insulin receptor substrate 4. (1254 aa)
PPARAPeroxisome proliferator activated receptor alpha. (468 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1253 aa)
SLC27A4Solute carrier family 27 member 4. (647 aa)
ENSGGOP00000039339Uncharacterized protein. (632 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (443 aa)
XBP1BZIP domain-containing protein. (380 aa)
SOGA1Suppressor of glucose, autophagy associated 1. (1608 aa)
CPEB1RRM domain-containing protein. (530 aa)
CPEB2Cytoplasmic polyadenylation element binding protein 2. (907 aa)
ENSGGOP00000037396Uncharacterized protein. (509 aa)
SCAPSSD domain-containing protein. (338 aa)
ENSGGOP00000036972Uncharacterized protein. (78 aa)
ENSGGOP00000035607Uncharacterized protein. (125 aa)
LPIN1Lipin 1. (975 aa)
ZFP36L1ZFP36 ring finger protein like 1. (338 aa)
ENSGGOP00000034697Hydroxyacyl-CoA dehydrogenase. (390 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (840 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
MAXMYC associated factor X. (148 aa)
IRS1Insulin receptor substrate 1. (1241 aa)
C2CD5C2 calcium dependent domain containing 5. (1084 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (543 aa)
BAIAP2BAI1 associated protein 2. (548 aa)
ENSGGOP00000030268Uncharacterized protein. (596 aa)
ENSGGOP00000030210Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (612 aa)
SELENOSUncharacterized protein. (218 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (244 aa)
ENSGGOP00000028878Forkhead box O4. (505 aa)
G3SKI0_GORGOUncharacterized protein. (1294 aa)
VGFUncharacterized protein. (336 aa)
TSC1TSC complex subunit 1. (1164 aa)
HADHAHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. (763 aa)
RAB31RAB31, member RAS oncogene family. (195 aa)
G3SHS9_GORGOANK_REP_REGION domain-containing protein. (499 aa)
PNPLA3Patatin like phospholipase domain containing 3. (447 aa)
SLC2A8Solute carrier family 2 member 8; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (454 aa)
STAT1Signal transducer and activator of transcription. (777 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
GRB14Growth factor receptor bound protein 14. (476 aa)
G3SCN9_GORGOUncharacterized protein. (572 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
CRY1Cryptochrome circadian regulator 1. (623 aa)
G3SAN6_GORGOAnkyrin repeat domain 30A. (1318 aa)
PDPK1Protein kinase domain-containing protein. (347 aa)
RAB13Uncharacterized protein. (203 aa)
HDAC9Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1066 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (387 aa)
G3S7H0_GORGOAdaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (646 aa)
NDEL1NudE neurodevelopment protein 1 like 1. (345 aa)
PCSK9Proprotein convertase subtilisin/kexin type 9; Crucial player in the regulation of plasma cholesterol homeostasis. Binds to low-density lipid receptor family members: low density lipoprotein receptor (LDLR), very low density lipoprotein receptor (VLDLR), apolipoprotein E receptor (LRP1/APOER) and apolipoprotein receptor 2 (LRP8/APOER2), and promotes their degradation in intracellular acidic compartments. Acts via a non-proteolytic mechanism to enhance the degradation of the hepatic LDLR through a clathrin LDLRAP1/ARH-mediated pathway. May prevent the recycling of LDLR from endosomes to [...] (690 aa)
CEACAM1Carcinoembryonic antigen related cell adhesion molecule 1. (525 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
SLC25A33Solute carrier family 25 member 33; Belongs to the mitochondrial carrier (TC 2.A.29) family. (321 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (492 aa)
G3RY68_GORGOChymotrypsin like elastase 2A; Belongs to the peptidase S1 family. (269 aa)
G3RXW1_GORGOProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (372 aa)
SYAP1Synapse associated protein 1. (352 aa)
EPM2AIP1EPM2A interacting protein 1. (607 aa)
KAT2BHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (820 aa)
RAB10RAB10, member RAS oncogene family. (200 aa)
AP3S1Clat_adaptor_s domain-containing protein. (193 aa)
HDAC5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1122 aa)
G3RTJ0_GORGORas homolog family member Q. (200 aa)
PIK3R3Uncharacterized protein. (507 aa)
RPS6KB1Protein kinase domain-containing protein. (210 aa)
G3RT31_GORGOInsulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (277 aa)
G3RSU6_GORGOUncharacterized protein. (499 aa)
PIK3C2APhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1686 aa)
APCAPC regulator of WNT signaling pathway. (2844 aa)
SRCTyrosine-protein kinase. (542 aa)
INSRTyrosine-protein kinase receptor. (1347 aa)
G3RPB0_GORGOUncharacterized protein. (351 aa)
G3RMA5_GORGOTyrosine-protein phosphatase non-receptor type. (415 aa)
G3RLC3_GORGOSH2 domain-containing protein. (568 aa)
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1. (1054 aa)
G3RKQ9_GORGOCCDC144C domain-containing protein. (314 aa)
G3RKH1_GORGOZinc finger DHHC-type containing 7. (312 aa)
SRD5A13-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (259 aa)
SRSF5Serine and arginine rich splicing factor 5. (272 aa)
G3RJZ9_GORGORB transcriptional corepressor 1. (756 aa)
ABCC8ATP binding cassette subfamily C member 8. (1582 aa)
INSIG2Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (225 aa)
TBC1D4TBC1 domain family member 4. (1298 aa)
PDK2Protein-serine/threonine kinase. (407 aa)
IRS2Insulin receptor substrate 2. (1220 aa)
INHBBInhibin subunit beta B. (407 aa)
G3RGY7_GORGOEukaryotic elongation factor 2 kinase. (638 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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