STRINGSTRING
PPM1F PPM1F PTEN PTEN DKK1 DKK1 INPP5J INPP5J PWP1 PWP1 G3QW80_GORGO G3QW80_GORGO INPP5K INPP5K BAX BAX SMAD7 SMAD7 GADD45A GADD45A BDKRB2 BDKRB2 G3RLB4_GORGO G3RLB4_GORGO G3RNB7_GORGO G3RNB7_GORGO BAK1 BAK1 CAV1 CAV1 NCK1 NCK1 DMTN DMTN NCK2 NCK2 ENSGGOP00000031106 ENSGGOP00000031106 ENSGGOP00000031130 ENSGGOP00000031130 GGNBP2 GGNBP2 PAQR3 PAQR3 EPM2A EPM2A DMD DMD HGF HGF PDE4D PDE4D INPP5F INPP5F RASSF2 RASSF2 DDIT4 DDIT4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PPM1FProtein phosphatase, Mg2+/Mn2+ dependent 1F. (454 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
DKK1Dickkopf-related protein 1. (266 aa)
INPP5JInositol polyphosphate-5-phosphatase J. (1007 aa)
PWP1WD_REPEATS_REGION domain-containing protein. (406 aa)
G3QW80_GORGOGlycerol-3-phosphate dehydrogenase [NAD(+)]. (315 aa)
INPP5KInositol polyphosphate-5-phosphatase K. (448 aa)
BAXBCL2 associated X, apoptosis regulator. (217 aa)
SMAD7MH2 domain-containing protein. (211 aa)
GADD45AGrowth arrest and DNA damage inducible alpha. (165 aa)
BDKRB2Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. (391 aa)
G3RLB4_GORGOMLX interacting protein like. (764 aa)
G3RNB7_GORGOUncharacterized protein. (661 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (147 aa)
NCK1Cytoplasmic protein. (377 aa)
DMTNDematin actin binding protein. (405 aa)
NCK2Cytoplasmic protein. (380 aa)
ENSGGOP00000031106WD_REPEATS_REGION domain-containing protein. (321 aa)
ENSGGOP00000031130Uncharacterized protein. (189 aa)
GGNBP2Gametogenetin binding protein 2. (688 aa)
PAQR3Progestin and adipoQ receptor family member 3. (311 aa)
EPM2AEPM2A glucan phosphatase, laforin. (275 aa)
DMDDystrophin. (3685 aa)
HGFHepatocyte growth factor; Belongs to the peptidase S1 family. (733 aa)
PDE4DPhosphodiesterase. (748 aa)
INPP5FInositol polyphosphate-5-phosphatase F. (1129 aa)
RASSF2Ras association domain family member 2. (326 aa)
DDIT4DNA damage inducible transcript 4. (232 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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