STRINGSTRING
ENSGGOP00000051675 ENSGGOP00000051675 SLC1A1 SLC1A1 BCL2 BCL2 PTEN PTEN TACR1 TACR1 LPAR5 LPAR5 ASIC4 ASIC4 RET RET G3QNE4_GORGO G3QNE4_GORGO MORC1 MORC1 SLC6A2 SLC6A2 BRINP1 BRINP1 HTR1A HTR1A G3QUU8_GORGO G3QUU8_GORGO NMUR2 NMUR2 MAPK8IP2 MAPK8IP2 G3QYC6_GORGO G3QYC6_GORGO TRPV1 TRPV1 P2RX2 P2RX2 NR2E1 NR2E1 HMGCS2 HMGCS2 G3R467_GORGO G3R467_GORGO EIF4E EIF4E MTOR MTOR VDAC1 VDAC1 G3R664_GORGO G3R664_GORGO NR4A2 NR4A2 SELENON SELENON UCN UCN EIF4G1 EIF4G1 CALCA CALCA EDNRB EDNRB LYPD1 LYPD1 ALS2 ALS2 G3RIH3_GORGO G3RIH3_GORGO DBH DBH PENK PENK USP46 USP46 G3RNB7_GORGO G3RNB7_GORGO RPS6KB1 RPS6KB1 TRPA1 TRPA1 MDK MDK ATP1A2 ATP1A2 ADRA2A ADRA2A G3S841_GORGO G3S841_GORGO SCN9A SCN9A THBS4 THBS4 NEUROD2 NEUROD2 ADRB1 ADRB1 NOS1 NOS1 UMOD UMOD G3SHZ0_GORGO G3SHZ0_GORGO DPP4 DPP4 G3SIC3_GORGO G3SIC3_GORGO IDO1 IDO1 HTR2C HTR2C ENSGGOP00000032712 ENSGGOP00000032712 PPP3CA PPP3CA ENSGGOP00000033982 ENSGGOP00000033982 PRKCG PRKCG P2RX3 P2RX3 NTRK1 NTRK1 DRD1 DRD1 RELN RELN GRIK2 GRIK2 ENSGGOP00000043921 ENSGGOP00000043921 MECP2 MECP2 LRP11 LRP11 FBXL20 FBXL20 GABRA5 GABRA5 ENSGGOP00000046735 ENSGGOP00000046735 TAC1 TAC1 ENSGGOP00000047330 ENSGGOP00000047330 PIRT PIRT ENSGGOP00000048104 ENSGGOP00000048104 THBS1 THBS1 ENSGGOP00000050849 ENSGGOP00000050849
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSGGOP00000051675Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (174 aa)
SLC1A1Amino acid transporter. (524 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
TACR1Tachykinin receptor 1; Belongs to the G-protein coupled receptor 1 family. (407 aa)
LPAR5Lysophosphatidic acid receptor 5; Belongs to the G-protein coupled receptor 1 family. (372 aa)
ASIC4Acid sensing ion channel subunit family member 4; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (666 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1114 aa)
G3QNE4_GORGOAcid sensing ion channel subunit 1; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (528 aa)
MORC1MORC family CW-type zinc finger 1. (984 aa)
SLC6A2Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (628 aa)
BRINP1BMP/retinoic acid inducible neural specific 1. (761 aa)
HTR1A5-hydroxytryptamine receptor 1A; G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second [...] (422 aa)
G3QUU8_GORGOUncharacterized protein. (870 aa)
NMUR2Neuromedin U receptor 2; Belongs to the G-protein coupled receptor 1 family. (414 aa)
MAPK8IP2Mitogen-activated protein kinase 8 interacting protein 2. (847 aa)
G3QYC6_GORGOCalpain 2; Belongs to the peptidase C2 family. (673 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (850 aa)
P2RX2P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (411 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (422 aa)
HMGCS23-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa)
G3R467_GORGOTranslocator protein. (169 aa)
EIF4EUncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (212 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2520 aa)
VDAC1Voltage dependent anion channel 1. (289 aa)
G3R664_GORGOUncharacterized protein. (226 aa)
NR4A2Nuclear receptor subfamily 4 group A member 2. (598 aa)
SELENONSelenoprotein N. (495 aa)
UCNUrocortin. (124 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1. (1603 aa)
CALCACalcitonin related polypeptide alpha. (141 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (532 aa)
LYPD1LY6/PLAUR domain containing 1. (141 aa)
ALS2Alsin Rho guanine nucleotide exchange factor ALS2. (1638 aa)
G3RIH3_GORGOADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (524 aa)
DBHDopamine beta-hydroxylase. (617 aa)
PENKProenkephalin. (267 aa)
USP46Ubiquitin specific peptidase 46; Belongs to the peptidase C19 family. (370 aa)
G3RNB7_GORGOUncharacterized protein. (661 aa)
RPS6KB1Protein kinase domain-containing protein. (210 aa)
TRPA1Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1119 aa)
MDKMidkine. (143 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
ADRA2AAdrenoceptor alpha 2A. (465 aa)
G3S841_GORGOUncharacterized protein. (245 aa)
SCN9ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1988 aa)
THBS4Thrombospondin 4. (961 aa)
NEUROD2Neurogenic differentiation factor. (382 aa)
ADRB1G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (291 aa)
NOS1Nitric oxide synthase 1. (1468 aa)
UMODUromodulin. (690 aa)
G3SHZ0_GORGOG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (339 aa)
DPP4Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (766 aa)
G3SIC3_GORGOUncharacterized protein. (337 aa)
IDO1Indoleamine 2,3-dioxygenase 1. (403 aa)
HTR2C5-hydroxytryptamine receptor 2C. (458 aa)
ENSGGOP00000032712Uncharacterized protein. (264 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
ENSGGOP00000033982Uncharacterized protein. (256 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (698 aa)
P2RX3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (397 aa)
NTRK1Tyrosine-protein kinase receptor. (796 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (446 aa)
RELNReelin. (3455 aa)
GRIK2Glutamate ionotropic receptor kainate type subunit 2. (908 aa)
ENSGGOP00000043921P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (395 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa)
LRP11LDL receptor related protein 11. (496 aa)
FBXL20F-box and leucine rich repeat protein 20. (438 aa)
GABRA5Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (462 aa)
ENSGGOP00000046735Non-specific serine/threonine protein kinase. (524 aa)
TAC1Tachykinin precursor 1. (129 aa)
ENSGGOP00000047330Uncharacterized protein. (261 aa)
PIRTPhosphoinositide interacting regulator of transient receptor potential channels. (137 aa)
ENSGGOP00000048104annotation not available (264 aa)
THBS1Thrombospondin 1. (1173 aa)
ENSGGOP00000050849Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (220 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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