STRINGSTRING
FLOT1 FLOT1 G3QJ42_GORGO G3QJ42_GORGO MFHAS1 MFHAS1 CD300A CD300A TLR2 TLR2 G3QH29_GORGO G3QH29_GORGO BPIFB1 BPIFB1 TNFAIP3 TNFAIP3 G3QMP2_GORGO G3QMP2_GORGO GFI1 GFI1 ARRB2 ARRB2 G3QS66_GORGO G3QS66_GORGO BIRC3 BIRC3 NFKBIL1 NFKBIL1 CD36 CD36 F2RL1 F2RL1 G3QX51_GORGO G3QX51_GORGO LTF LTF BIRC2 BIRC2 NR1H3 NR1H3 IFI35 IFI35 NR1D1 NR1D1 ESR1 ESR1 CD14 CD14 RSAD2 RSAD2 NOD2 NOD2 SARM1 SARM1 LYN LYN CACTIN CACTIN APPL2 APPL2 GPR108 GPR108 PELI1 PELI1 CD300LF CD300LF FCRL3 FCRL3 G3RD62_GORGO G3RD62_GORGO IRF1 IRF1 G3REJ1_GORGO G3REJ1_GORGO SLC15A4 SLC15A4 SMPDL3B SMPDL3B TREM2 TREM2 UBQLN1 UBQLN1 NINJ1 NINJ1 G3RQF4_GORGO G3RQF4_GORGO G3RR23_GORGO G3RR23_GORGO RTN4 RTN4 TIRAP TIRAP CXHXorf21 CXHXorf21 G3RX18_GORGO G3RX18_GORGO G3RXW1_GORGO G3RXW1_GORGO CAV1 CAV1 G3S7H0_GORGO G3S7H0_GORGO LILRA4 LILRA4 G3S905_GORGO G3S905_GORGO PDPK1 PDPK1 LGR4 LGR4 G3SFI2_GORGO G3SFI2_GORGO TLR3 TLR3 DDX3X DDX3X G3SKW3_GORGO G3SKW3_GORGO ENSGGOP00000029038 ENSGGOP00000029038 ENSGGOP00000031193 ENSGGOP00000031193 DAB2IP DAB2IP ENSGGOP00000033484 ENSGGOP00000033484 GRAMD4 GRAMD4 IRF7 IRF7 PJA2 PJA2 NLRP6 NLRP6 RAB7B RAB7B IRF4 IRF4 ACOD1 ACOD1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FLOT1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa)
G3QJ42_GORGOOTU domain-containing protein. (1058 aa)
MFHAS1Malignant fibrous histiocytoma amplified sequence 1. (1010 aa)
CD300ACD300a molecule. (299 aa)
TLR2Toll-like receptor 2; Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). May also promote apoptosis in response to lipoproteins. Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequentl [...] (784 aa)
G3QH29_GORGOG protein pathway suppressor 2. (327 aa)
BPIFB1BPI fold containing family B member 1. (484 aa)
TNFAIP3TNF alpha induced protein 3. (790 aa)
G3QMP2_GORGOProtein tyrosine phosphatase non-receptor type 22. (693 aa)
GFI1Growth factor independent 1 transcriptional repressor. (422 aa)
ARRB2Arrestin beta 2. (409 aa)
G3QS66_GORGOUncharacterized protein. (333 aa)
BIRC3Baculoviral IAP repeat containing 3. (604 aa)
NFKBIL1NFKB inhibitor like 1. (381 aa)
CD36CD36 molecule; Belongs to the CD36 family. (472 aa)
F2RL1F2R like trypsin receptor 1. (397 aa)
G3QX51_GORGOLipopolysaccharide binding protein. (481 aa)
LTFLactotransferrin; Belongs to the transferrin family. (711 aa)
BIRC2Baculoviral IAP repeat containing 2. (618 aa)
NR1H3Nuclear receptor subfamily 1 group H member 3. (453 aa)
IFI35Interferon induced protein 35. (286 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (614 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
CD14Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (375 aa)
RSAD2Elp3 domain-containing protein. (361 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1040 aa)
SARM1Sterile alpha and TIR motif containing 1. (724 aa)
LYNTyrosine-protein kinase. (512 aa)
CACTINCactin, spliceosome C complex subunit. (759 aa)
APPL2Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (670 aa)
GPR108G protein-coupled receptor 108. (543 aa)
PELI1E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
CD300LFCD300 molecule like family member f. (305 aa)
FCRL3Fc receptor like 3. (741 aa)
G3RD62_GORGOUncharacterized protein. (488 aa)
IRF1Interferon regulatory factor. (325 aa)
G3REJ1_GORGOLeucine rich repeat containing 14. (493 aa)
SLC15A4Solute carrier family 15 member 4. (577 aa)
SMPDL3BAcid sphingomyelinase-like phosphodiesterase. (455 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (230 aa)
UBQLN1Ubiquilin 1. (589 aa)
NINJ1Ninjurin 1. (152 aa)
G3RQF4_GORGOLeukocyte immunoglobulin like receptor A2. (483 aa)
G3RR23_GORGOUncharacterized protein. (210 aa)
RTN4Reticulon. (1192 aa)
TIRAPTIR domain containing adaptor protein. (221 aa)
CXHXorf21Chromosome X open reading frame 21. (301 aa)
G3RX18_GORGOUncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (805 aa)
G3RXW1_GORGOProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (372 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (147 aa)
G3S7H0_GORGOAdaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (646 aa)
LILRA4Leukocyte immunoglobulin like receptor A4. (499 aa)
G3S905_GORGOUncharacterized protein. (134 aa)
PDPK1Protein kinase domain-containing protein. (347 aa)
LGR4Leucine rich repeat containing G protein-coupled receptor 4. (929 aa)
G3SFI2_GORGOProtein tyrosine phosphatase receptor type S. (1822 aa)
TLR3Toll-like receptor 3 precursor; Belongs to the Toll-like receptor family. (904 aa)
DDX3XDEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. (733 aa)
G3SKW3_GORGOTriggering receptor expressed on myeloid cells like 4. (188 aa)
ENSGGOP00000029038TYRO3 protein tyrosine kinase. (901 aa)
ENSGGOP00000031193Uncharacterized protein. (93 aa)
DAB2IPDAB2 interacting protein. (1155 aa)
ENSGGOP00000033484Uncharacterized protein. (184 aa)
GRAMD4GRAM domain containing 4. (600 aa)
IRF7Interferon regulatory factor 7. (516 aa)
PJA2Uncharacterized protein. (437 aa)
NLRP6Uncharacterized protein. (912 aa)
RAB7BRAB7B, member RAS oncogene family. (174 aa)
IRF4Interferon regulatory factor 4. (451 aa)
ACOD1Aconitate decarboxylase 1. (481 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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