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PELI1 PELI1 CD14 CD14 IFI35 IFI35 NR1H3 NR1H3 LTF LTF G3QX51_GORGO G3QX51_GORGO F2RL1 F2RL1 G3QS66_GORGO G3QS66_GORGO G3QMP2_GORGO G3QMP2_GORGO NINJ1 NINJ1 TIRAP TIRAP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PELI1E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
CD14Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (375 aa)
IFI35Interferon induced protein 35. (286 aa)
NR1H3Nuclear receptor subfamily 1 group H member 3. (453 aa)
LTFLactotransferrin; Belongs to the transferrin family. (711 aa)
G3QX51_GORGOLipopolysaccharide binding protein. (481 aa)
F2RL1F2R like trypsin receptor 1. (397 aa)
G3QS66_GORGOUncharacterized protein. (333 aa)
G3QMP2_GORGOProtein tyrosine phosphatase non-receptor type 22. (693 aa)
NINJ1Ninjurin 1. (152 aa)
TIRAPTIR domain containing adaptor protein. (221 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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