STRINGSTRING
KMT2E KMT2E RRP8 RRP8 ENSGGOP00000051240 ENSGGOP00000051240 CBX5 CBX5 PHF1 PHF1 TDRD3 TDRD3 ENSGGOP00000050634 ENSGGOP00000050634 ENSGGOP00000050061 ENSGGOP00000050061 ZMYND8 ZMYND8 ING2 ING2 CXXC1 CXXC1 LRWD1 LRWD1 L3MBTL2 L3MBTL2 ENSGGOP00000045725 ENSGGOP00000045725 RBBP5 RBBP5 ZCWPW2 ZCWPW2 ENSGGOP00000045067 ENSGGOP00000045067 PYGO1 PYGO1 C5H17orf64 C5H17orf64 ENSGGOP00000044212 ENSGGOP00000044212 ENSGGOP00000043307 ENSGGOP00000043307 ENSGGOP00000043155 ENSGGOP00000043155 ENSGGOP00000042743 ENSGGOP00000042743 ENSGGOP00000041900 ENSGGOP00000041900 ENSGGOP00000041537 ENSGGOP00000041537 ATRX ATRX ENSGGOP00000039820 ENSGGOP00000039820 PHF19 PHF19 ENSGGOP00000038029 ENSGGOP00000038029 ENSGGOP00000035374 ENSGGOP00000035374 ENSGGOP00000035262 ENSGGOP00000035262 DPF2 DPF2 ENSGGOP00000032369 ENSGGOP00000032369 CHD8 CHD8 CHD5 CHD5 ENSGGOP00000030794 ENSGGOP00000030794 NCAPG2 NCAPG2 MBTD1 MBTD1 PHF2 PHF2 RAG2 RAG2 HDGFL2 HDGFL2 BPTF BPTF CBX1 CBX1 CDYL CDYL KDM4A KDM4A G3RVX3_GORGO G3RVX3_GORGO UHRF1 UHRF1 CBX3 CBX3 MSH6 MSH6 G3RNS0_GORGO G3RNS0_GORGO GLYR1 GLYR1 ING4 ING4 G3RFN1_GORGO G3RFN1_GORGO PHF8 PHF8 KAT8 KAT8 DPPA3 DPPA3 ING1 ING1 MORC3 MORC3 MORC4 MORC4 G3R765_GORGO G3R765_GORGO FMR1 FMR1 SUZ12 SUZ12 CBX2 CBX2 CBX4 CBX4 ZZZ3 ZZZ3 SPIN1 SPIN1 PHF13 PHF13 NCAPD3 NCAPD3 PWP1 PWP1 MSL3 MSL3 KDM8 KDM8 CDYL2 CDYL2 ZCWPW1 ZCWPW1 WDR5 WDR5 CBX7 CBX7 CBX8 CBX8 G3QNY7_GORGO G3QNY7_GORGO SETD5 SETD5 KDM7A KDM7A SPIN4 SPIN4 TP53BP1 TP53BP1 ZZEF1 ZZEF1 MTF2 MTF2 PWWP2A PWWP2A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KMT2ELysine methyltransferase 2E. (1858 aa)
RRP8Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...] (456 aa)
ENSGGOP00000051240Uncharacterized protein. (157 aa)
CBX5Chromobox 5. (191 aa)
PHF1PHD finger protein 1. (567 aa)
TDRD3Tudor domain containing 3. (730 aa)
ENSGGOP00000050634Uncharacterized protein. (61 aa)
ENSGGOP00000050061Uncharacterized protein. (106 aa)
ZMYND8Zinc finger MYND-type containing 8. (1241 aa)
ING2Inhibitor of growth protein. (280 aa)
CXXC1CXXC finger protein 1. (687 aa)
LRWD1Leucine rich repeats and WD repeat domain containing 1. (664 aa)
L3MBTL2L3MBTL histone methyl-lysine binding protein 2. (709 aa)
ENSGGOP00000045725Zinc finger MYND-type containing 11. (645 aa)
RBBP5RB binding protein 5, histone lysine methyltransferase complex subunit. (548 aa)
ZCWPW2Zinc finger CW-type and PWWP domain containing 2. (356 aa)
ENSGGOP00000045067Tudor domain containing 3. (116 aa)
PYGO1Pygopus family PHD finger 1. (419 aa)
C5H17orf64DUF4208 domain-containing protein. (143 aa)
ENSGGOP00000044212Uncharacterized protein. (257 aa)
ENSGGOP00000043307Uncharacterized protein. (421 aa)
ENSGGOP00000043155Tubulin tyrosine ligase like 12. (640 aa)
ENSGGOP00000042743ING domain-containing protein. (174 aa)
ENSGGOP00000041900Uncharacterized protein. (138 aa)
ENSGGOP00000041537Uncharacterized protein. (130 aa)
ATRXATRX chromatin remodeler. (2492 aa)
ENSGGOP00000039820Chromo domain-containing protein. (174 aa)
PHF19PHD finger protein 19. (599 aa)
ENSGGOP00000038029WD_REPEATS_REGION domain-containing protein. (276 aa)
ENSGGOP00000035374Uncharacterized protein. (150 aa)
ENSGGOP00000035262Uncharacterized protein. (173 aa)
DPF2Double PHD fingers 2. (405 aa)
ENSGGOP00000032369Uncharacterized protein. (213 aa)
CHD8Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2589 aa)
CHD5Chromodomain helicase DNA binding protein 5. (1957 aa)
ENSGGOP00000030794THAP domain containing 7. (345 aa)
NCAPG2Non-SMC condensin II complex subunit G2. (1156 aa)
MBTD1Mbt domain containing 1. (630 aa)
PHF2PHD finger protein 2. (1100 aa)
RAG2Recombination activating 2. (527 aa)
HDGFL2HDGF like 2. (707 aa)
BPTFBromodomain PHD finger transcription factor. (2869 aa)
CBX1Chromobox 1. (185 aa)
CDYLChromodomain Y like. (598 aa)
KDM4AUncharacterized protein. (1064 aa)
G3RVX3_GORGOLysine demethylase 5A. (1510 aa)
UHRF1Ubiquitin like with PHD and ring finger domains 1. (793 aa)
CBX3Uncharacterized protein. (183 aa)
MSH6DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1360 aa)
G3RNS0_GORGOJumonji domain containing 7. (316 aa)
GLYR1Glyoxylate reductase 1 homolog. (553 aa)
ING4Inhibitor of growth protein. (248 aa)
G3RFN1_GORGOUncharacterized protein. (344 aa)
PHF8PHD finger protein 8. (1060 aa)
KAT8Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (467 aa)
DPPA3Uncharacterized protein. (159 aa)
ING1Inhibitor of growth protein. (421 aa)
MORC3MORC family CW-type zinc finger 3. (939 aa)
MORC4CW-type domain-containing protein. (817 aa)
G3R765_GORGOChromodomain helicase DNA binding protein 1. (1679 aa)
FMR1Fragile X mental retardation 1. (624 aa)
SUZ12SUZ12 polycomb repressive complex 2 subunit. (610 aa)
CBX2Chromobox 2. (532 aa)
CBX4Chromobox 4. (550 aa)
ZZZ3Uncharacterized protein. (903 aa)
SPIN1Spindlin 1. (262 aa)
PHF13PHD domain-containing protein. (421 aa)
NCAPD3Condensin-2 complex subunit D3; Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. (1498 aa)
PWP1WD_REPEATS_REGION domain-containing protein. (406 aa)
MSL3MSL complex subunit 3. (521 aa)
KDM8Lysine demethylase 8. (454 aa)
CDYL2Chromodomain Y like 2. (501 aa)
ZCWPW1Zinc finger CW-type and PWWP domain containing 1. (648 aa)
WDR5WD repeat domain 5. (334 aa)
CBX7Chromobox 7. (259 aa)
CBX8Chromobox 8. (389 aa)
G3QNY7_GORGOInhibitor of growth protein. (353 aa)
SETD5SET domain containing 5. (1461 aa)
KDM7ALysine demethylase 7A. (876 aa)
SPIN4Spindlin family member 4. (249 aa)
TP53BP1Tumor protein p53 binding protein 1. (1972 aa)
ZZEF1Zinc finger ZZ-type and EF-hand domain containing 1. (2961 aa)
MTF2Metal response element binding transcription factor 2. (593 aa)
PWWP2APWWP domain containing 2A. (755 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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