STRINGSTRING
DYNC1H1 DYNC1H1 SERPINA3 SERPINA3 G3QER8_GORGO G3QER8_GORGO G3QER9_GORGO G3QER9_GORGO G3QF49_GORGO G3QF49_GORGO DNAJC3 DNAJC3 HEBP2 HEBP2 HRNR HRNR CTSC CTSC CREG1 CREG1 VCP VCP PRKCD PRKCD STK11IP STK11IP MNDA MNDA CCT2 CCT2 CCT8 CCT8 TRAPPC1 TRAPPC1 G3QUU9_GORGO G3QUU9_GORGO FUCA1 FUCA1 ACTR10 ACTR10 G3QWH3_GORGO G3QWH3_GORGO G3QX42_GORGO G3QX42_GORGO AGA AGA GGH GGH ADA2 ADA2 GLA GLA HEXB HEXB RETN RETN ANXA2 ANXA2 FUCA2 FUCA2 G3R9G9_GORGO G3R9G9_GORGO G3RD46_GORGO G3RD46_GORGO PYGB PYGB DSN1 DSN1 GM2A GM2A GRN GRN PRSS57 PRSS57 PADI2 PADI2 ENSGGOP00000043036 ENSGGOP00000043036 ENSGGOP00000051960 ENSGGOP00000051960 TXNDC5 TXNDC5 FABP5 FABP5 ENSGGOP00000051215 ENSGGOP00000051215 ENSGGOP00000050742 ENSGGOP00000050742 CAP1 CAP1 NHLRC3 NHLRC3 MPO MPO ENSGGOP00000048279 ENSGGOP00000048279 FTL FTL ENSGGOP00000043046 ENSGGOP00000043046 PYCARD PYCARD FAF2 FAF2 G3RPZ7_GORGO G3RPZ7_GORGO ARG1 ARG1 PSMD1 PSMD1 ACLY ACLY VAT1 VAT1 G3RZJ4_GORGO G3RZJ4_GORGO G3S0H1_GORGO G3S0H1_GORGO G3S0U2_GORGO G3S0U2_GORGO GDI2 GDI2 PRDX6 PRDX6 C3 C3 G3SGI1_GORGO G3SGI1_GORGO ENSGGOP00000043038 ENSGGOP00000043038 G3SJX1_GORGO G3SJX1_GORGO PTGES2 PTGES2 FRK FRK CPPED1 CPPED1 ENSGGOP00000029822 ENSGGOP00000029822 ENSGGOP00000030302 ENSGGOP00000030302 IST1 IST1 ENSGGOP00000031381 ENSGGOP00000031381 SDCBP SDCBP ENSGGOP00000032279 ENSGGOP00000032279 ENSGGOP00000032912 ENSGGOP00000032912 ENSGGOP00000033713 ENSGGOP00000033713 ENSGGOP00000034385 ENSGGOP00000034385 CTSA CTSA ENSGGOP00000035310 ENSGGOP00000035310 ENSGGOP00000035502 ENSGGOP00000035502 ENSGGOP00000035808 ENSGGOP00000035808 ARHGAP45 ARHGAP45 PA2G4 PA2G4 ENSGGOP00000036928 ENSGGOP00000036928 GLB1 GLB1 ARSB ARSB ENSGGOP00000039441 ENSGGOP00000039441 GCA GCA MAPK1 MAPK1 C6H6orf120 C6H6orf120 IMPDH-2 IMPDH-2 ENSGGOP00000042613 ENSGGOP00000042613 GALNS GALNS ENSGGOP00000042926 ENSGGOP00000042926
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DYNC1H1Dynein cytoplasmic 1 heavy chain 1. (4646 aa)
SERPINA3Serpin family A member 3; Belongs to the serpin family. (448 aa)
G3QER8_GORGOProteinase 3; Belongs to the peptidase S1 family. (256 aa)
G3QER9_GORGOElastase, neutrophil expressed; Belongs to the peptidase S1 family. (246 aa)
G3QF49_GORGOAzurocidin 1. (251 aa)
DNAJC3DnaJ heat shock protein family (Hsp40) member C3. (504 aa)
HEBP2Heme binding protein 2. (205 aa)
HRNREF-hand domain-containing protein. (2145 aa)
CTSCCathepsin C; Belongs to the peptidase C1 family. (463 aa)
CREG1Cellular repressor of E1A stimulated genes 1; Belongs to the CREG family. (220 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (806 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
STK11IPSerine/threonine kinase 11 interacting protein. (1088 aa)
MNDAMyeloid cell nuclear differentiation antigen. (407 aa)
CCT2Chaperonin containing TCP1 subunit 2. (535 aa)
CCT8Chaperonin containing TCP1 subunit 8. (548 aa)
TRAPPC1Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family. (145 aa)
G3QUU9_GORGOProtein S100; Belongs to the S-100 family. (101 aa)
FUCA1Alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. (466 aa)
ACTR10Actin related protein 10; Belongs to the actin family. (417 aa)
G3QWH3_GORGOArylsulfatase A. (465 aa)
G3QX42_GORGOBactericidal permeability increasing protein. (487 aa)
AGAAspartylglucosaminidase. (346 aa)
GGHFolate gamma-glutamyl hydrolase. (318 aa)
ADA2Adenosine deaminase 2. (511 aa)
GLAGalactosidase alpha; Belongs to the glycosyl hydrolase 27 family. (370 aa)
HEXBBeta-hexosaminidase. (519 aa)
RETNResistin. (108 aa)
ANXA2Annexin. (357 aa)
FUCA2Alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. (468 aa)
G3R9G9_GORGOToll interacting protein. (223 aa)
G3RD46_GORGOCathepsin G; Belongs to the peptidase S1 family. (255 aa)
PYGBAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (762 aa)
DSN1DSN1 component of MIS12 kinetochore complex. (356 aa)
GM2AGM2 ganglioside activator. (193 aa)
GRNGranulin precursor. (593 aa)
PRSS57Serine protease 57; Belongs to the peptidase S1 family. (282 aa)
PADI2Peptidyl arginine deiminase 2. (665 aa)
ENSGGOP00000043036Alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. (397 aa)
ENSGGOP00000051960Annexin. (330 aa)
TXNDC5Uncharacterized protein; Belongs to the protein disulfide isomerase family. (361 aa)
FABP5FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (129 aa)
ENSGGOP00000051215CBS domain-containing protein. (377 aa)
ENSGGOP00000050742Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (108 aa)
CAP1Adenylyl cyclase-associated protein; Belongs to the CAP family. (475 aa)
NHLRC3Uncharacterized protein. (135 aa)
MPOMyeloperoxidase. (747 aa)
ENSGGOP00000048279IMPDH domain-containing protein. (431 aa)
FTLFerritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (182 aa)
ENSGGOP00000043046Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (101 aa)
PYCARDPYD and CARD domain containing. (195 aa)
FAF2Fas associated factor family member 2. (445 aa)
G3RPZ7_GORGOUncharacterized protein. (482 aa)
ARG1Arginase. (322 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
ACLYATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. (1137 aa)
VAT1Vesicle amine transport 1. (394 aa)
G3RZJ4_GORGOGlucosamine (N-acetyl)-6-sulfatase. (583 aa)
G3S0H1_GORGOBeta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family. (675 aa)
G3S0U2_GORGOLipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (90 aa)
GDI2Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. (445 aa)
PRDX6Peroxiredoxin 6. (224 aa)
C3Complement C3. (1663 aa)
G3SGI1_GORGOPeptidase_M24 domain-containing protein. (181 aa)
ENSGGOP00000043038Thioredoxin domain-containing protein. (174 aa)
G3SJX1_GORGOUncharacterized protein; Belongs to the actin family. (353 aa)
PTGES2Prostaglandin E synthase 2. (377 aa)
FRKTyrosine-protein kinase. (505 aa)
CPPED1Calcineurin like phosphoesterase domain containing 1. (314 aa)
ENSGGOP00000029822NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (334 aa)
ENSGGOP00000030302PDZ domain-containing protein. (258 aa)
IST1Uncharacterized protein. (343 aa)
ENSGGOP00000031381Uncharacterized protein. (561 aa)
SDCBPSyndecan binding protein. (318 aa)
ENSGGOP00000032279Uncharacterized protein. (180 aa)
ENSGGOP00000032912Uncharacterized protein; Belongs to the actin family. (386 aa)
ENSGGOP00000033713Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (125 aa)
ENSGGOP00000034385Uncharacterized protein. (121 aa)
CTSACarboxypeptidase; Belongs to the peptidase S10 family. (501 aa)
ENSGGOP00000035310Peptidase_M24 domain-containing protein. (371 aa)
ENSGGOP00000035502Peptidase_M24 domain-containing protein. (143 aa)
ENSGGOP00000035808Uncharacterized protein. (272 aa)
ARHGAP45Rho GTPase activating protein 45. (1152 aa)
PA2G4Proliferation-associated 2G4. (394 aa)
ENSGGOP00000036928Uncharacterized protein. (504 aa)
GLB1Beta-galactosidase. (701 aa)
ARSBArylsulfatase B. (535 aa)
ENSGGOP00000039441Uncharacterized protein. (296 aa)
GCAGrancalcin. (217 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
C6H6orf120Chromosome 6 open reading frame 120. (191 aa)
IMPDH-2Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (628 aa)
ENSGGOP00000042613CBS domain-containing protein. (505 aa)
GALNSGalactosamine (N-acetyl)-6-sulfatase. (482 aa)
ENSGGOP00000042926Uncharacterized protein. (506 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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