(25 nodes) Response to muscle stretch network (Gorilla gorilla)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NFKBIA	NFKB inhibitor alpha. (317 aa)
	ENSGGOP00000049072	Protein kinase domain-containing protein. (296 aa)
	CTNNB1	Catenin beta 1. (781 aa)
	ENSGGOP00000045245	Ryanodine receptor 2. (4768 aa)
	ENSGGOP00000037657	Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
	DMD	Dystrophin. (3685 aa)
	GPI	Glucose-6-phosphate isomerase; Belongs to the GPI family. (573 aa)
	TTN	Titin. (32000 aa)
	RELA	RELA proto-oncogene, NF-kB subunit. (551 aa)
	RAF1	Raf-1 proto-oncogene, serine/threonine kinase. (630 aa)
	CDH2	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (886 aa)
	PTK2	Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
	NFKB1	Nuclear factor kappa B subunit 1. (969 aa)
	ANKRD23	Ankyrin repeat domain 23. (305 aa)
	EDN1	Endothelin 1. (212 aa)
	NPPA	Natriuretic peptide A. (153 aa)
	DDR2	Discoidin domain receptor tyrosine kinase 2. (855 aa)
	GSN	Gelsolin. (787 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	ANKRD1	Ankyrin repeat domain 1. (319 aa)
	TCAP	Titin-cap. (167 aa)
	CSRP3	Cysteine and glycine rich protein 3. (194 aa)
	SLC9A1	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
	FOS	Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKRD1	CSRP3	ENSGGOP00000007978	ENSGGOP00000004726	Ankyrin repeat domain 1.	Cysteine and glycine rich protein 3.	0.535
ANKRD1	ENSGGOP00000045245	ENSGGOP00000007978	ENSGGOP00000045245	Ankyrin repeat domain 1.	Ryanodine receptor 2.	0.536
ANKRD1	TCAP	ENSGGOP00000007978	ENSGGOP00000006954	Ankyrin repeat domain 1.	Titin-cap.	0.480
ANKRD1	TTN	ENSGGOP00000007978	ENSGGOP00000029524	Ankyrin repeat domain 1.	Titin.	0.828
ANKRD23	TTN	ENSGGOP00000014222	ENSGGOP00000029524	Ankyrin repeat domain 23.	Titin.	0.746
CAV3	CSRP3	ENSGGOP00000000134	ENSGGOP00000004726	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Cysteine and glycine rich protein 3.	0.535
CAV3	CTNNB1	ENSGGOP00000000134	ENSGGOP00000048898	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Catenin beta 1.	0.443
CAV3	DMD	ENSGGOP00000000134	ENSGGOP00000037644	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Dystrophin.	0.806
CAV3	ENSGGOP00000045245	ENSGGOP00000000134	ENSGGOP00000045245	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Ryanodine receptor 2.	0.559
CAV3	TCAP	ENSGGOP00000000134	ENSGGOP00000006954	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Titin-cap.	0.523
CAV3	TTN	ENSGGOP00000000134	ENSGGOP00000029524	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Titin.	0.553
CDH2	CTNNB1	ENSGGOP00000025824	ENSGGOP00000048898	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	Catenin beta 1.	0.998
CDH2	ENSGGOP00000049072	ENSGGOP00000025824	ENSGGOP00000049072	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	Protein kinase domain-containing protein.	0.426
CDH2	PTK2	ENSGGOP00000025824	ENSGGOP00000021868	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.442
CSRP3	ANKRD1	ENSGGOP00000004726	ENSGGOP00000007978	Cysteine and glycine rich protein 3.	Ankyrin repeat domain 1.	0.535
CSRP3	CAV3	ENSGGOP00000004726	ENSGGOP00000000134	Cysteine and glycine rich protein 3.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.535
CSRP3	NPPA	ENSGGOP00000004726	ENSGGOP00000012630	Cysteine and glycine rich protein 3.	Natriuretic peptide A.	0.523
CSRP3	TCAP	ENSGGOP00000004726	ENSGGOP00000006954	Cysteine and glycine rich protein 3.	Titin-cap.	0.946
CSRP3	TTN	ENSGGOP00000004726	ENSGGOP00000029524	Cysteine and glycine rich protein 3.	Titin.	0.875
CTNNB1	CAV3	ENSGGOP00000048898	ENSGGOP00000000134	Catenin beta 1.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.443